DE60039998D1 - Pentacyclische taxan-verbindungen - Google Patents

Pentacyclische taxan-verbindungen

Info

Publication number
DE60039998D1
DE60039998D1 DE60039998T DE60039998T DE60039998D1 DE 60039998 D1 DE60039998 D1 DE 60039998D1 DE 60039998 T DE60039998 T DE 60039998T DE 60039998 T DE60039998 T DE 60039998T DE 60039998 D1 DE60039998 D1 DE 60039998D1
Authority
DE
Germany
Prior art keywords
taxan
pentacyclic
compounds
taxan compounds
pentacyclic taxan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60039998T
Other languages
English (en)
Inventor
Soga
Uoto
Takeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Application granted granted Critical
Publication of DE60039998D1 publication Critical patent/DE60039998D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4355Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
DE60039998T 1999-10-15 2000-10-12 Pentacyclische taxan-verbindungen Expired - Lifetime DE60039998D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP29335699 1999-10-15
PCT/JP2000/007087 WO2001027115A1 (fr) 1999-10-15 2000-10-12 Composes pentacycliques au taxane

Publications (1)

Publication Number Publication Date
DE60039998D1 true DE60039998D1 (de) 2008-10-02

Family

ID=17793741

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60039998T Expired - Lifetime DE60039998D1 (de) 1999-10-15 2000-10-12 Pentacyclische taxan-verbindungen

Country Status (22)

Country Link
EP (1) EP1221445B1 (de)
JP (1) JP3776799B2 (de)
KR (1) KR100706566B1 (de)
CN (1) CN1203074C (de)
AR (1) AR026026A1 (de)
AT (1) ATE405569T1 (de)
AU (1) AU774787B2 (de)
BR (1) BR0014687A (de)
CA (1) CA2386772C (de)
DE (1) DE60039998D1 (de)
DK (1) DK1221445T3 (de)
ES (1) ES2311473T3 (de)
HK (1) HK1044000B (de)
IL (2) IL149007A0 (de)
MX (1) MXPA02003797A (de)
MY (1) MY125378A (de)
NO (1) NO328418B1 (de)
PT (1) PT1221445E (de)
RU (1) RU2257387C2 (de)
TW (1) TWI225062B (de)
WO (1) WO2001027115A1 (de)
ZA (1) ZA200202696B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60224440T2 (de) * 2001-11-29 2009-01-02 Daiichi Sankyo Co., Ltd. Kristalle von taxanderivaten und verfahren zu deren herstellung
TW200533339A (en) 2004-03-16 2005-10-16 Bristol Myers Squibb Co Therapeutic synergy of anti-cancer compounds
ATE526332T1 (de) 2004-04-30 2011-10-15 Daiichi Seiyaku Co Verfahren zur herstellung von pentacyclischem taxan
US20090186868A1 (en) * 2005-10-25 2009-07-23 Daiichi Sankyo Company Limited Taxane Compound Having Azetidine Ring Structure
CN100516067C (zh) * 2006-01-10 2009-07-22 上海恒瑞医药有限公司 具有抗肿瘤活性的紫杉酚衍生物
US8785669B2 (en) * 2010-06-30 2014-07-22 Gfv, Llc Taxane compounds, compositions and methods
EP2740477A1 (de) 2011-08-02 2014-06-11 Astellas Pharma Inc. Verfahren zur behandlung von krebs mittels kombinierter anwendung von wirkstoffen
FR2986526A1 (fr) 2012-02-03 2013-08-09 Sanofi Sa Procede de preparation de derives du taxol et certains composes intermediaires
CN104650109B (zh) * 2013-11-22 2019-01-01 江苏天士力帝益药业有限公司 紫杉烷类化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2712289B1 (fr) * 1993-11-08 1996-01-05 Rhone Poulenc Rorer Sa Nouveaux dérivés de taxicine, leur préparation et les compositions pharmaceutiques qui les contiennent.
CN1094940C (zh) * 1995-04-28 2002-11-27 第一制药株式会社 具有抗肿瘤活性的紫杉酚衍生物
TW527183B (en) * 1996-06-06 2003-04-11 Daiichi Seiyaku Co Drug complex

Also Published As

Publication number Publication date
IL149007A0 (en) 2002-11-10
CA2386772C (en) 2009-01-13
DK1221445T3 (da) 2008-11-24
ZA200202696B (en) 2003-09-23
NO20021753D0 (no) 2002-04-12
PT1221445E (pt) 2008-10-08
AR026026A1 (es) 2002-12-26
IL149007A (en) 2006-12-10
ATE405569T1 (de) 2008-09-15
JP3776799B2 (ja) 2006-05-17
CN1409714A (zh) 2003-04-09
NO20021753L (no) 2002-06-12
HK1044000B (zh) 2008-11-21
MXPA02003797A (es) 2002-12-13
MY125378A (en) 2006-07-31
CA2386772A1 (en) 2001-04-19
CN1203074C (zh) 2005-05-25
ES2311473T3 (es) 2009-02-16
KR20020035901A (ko) 2002-05-15
KR100706566B1 (ko) 2007-04-13
TWI225062B (en) 2004-12-11
AU774787B2 (en) 2004-07-08
EP1221445A1 (de) 2002-07-10
HK1044000A1 (en) 2002-10-04
BR0014687A (pt) 2002-11-19
AU7685100A (en) 2001-04-23
WO2001027115A1 (fr) 2001-04-19
NO328418B1 (no) 2010-02-15
EP1221445A4 (de) 2003-05-28
EP1221445B1 (de) 2008-08-20
RU2257387C2 (ru) 2005-07-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition