AT387380B - Verfahren und zwischenprodukte fuer n-(s-3alkyl-heptanoyl)-d-gamma-glutamyl-glycyl-dalanin - Google Patents

Verfahren und zwischenprodukte fuer n-(s-3alkyl-heptanoyl)-d-gamma-glutamyl-glycyl-dalanin

Info

Publication number
AT387380B
AT387380B AT0262887A AT262887A AT387380B AT 387380 B AT387380 B AT 387380B AT 0262887 A AT0262887 A AT 0262887A AT 262887 A AT262887 A AT 262887A AT 387380 B AT387380 B AT 387380B
Authority
AT
Austria
Prior art keywords
glycyl
glutamyl
gamma
dalanine
3alkyl
Prior art date
Application number
AT0262887A
Other languages
English (en)
Other versions
ATA262887A (de
Inventor
Charles William Murtiashaw
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ATA262887A publication Critical patent/ATA262887A/de
Application granted granted Critical
Publication of AT387380B publication Critical patent/AT387380B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/62—Preparation of carboxylic acid halides by reactions not involving the carboxylic acid halide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/27—Preparation of carboxylic acid esters from ortho-esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/303—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/533—Monocarboxylic acid esters having only one carbon-to-carbon double bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0262887A 1986-08-27 1987-10-08 Verfahren und zwischenprodukte fuer n-(s-3alkyl-heptanoyl)-d-gamma-glutamyl-glycyl-dalanin AT387380B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1986/001772 WO1988001612A1 (en) 1986-08-27 1986-08-27 Processes and intermediates for n-(s-3-alkyl-heptanoyl)-d-gamma-glutamyl-glycyl-d-alanine

Publications (2)

Publication Number Publication Date
ATA262887A ATA262887A (de) 1988-06-15
AT387380B true AT387380B (de) 1989-01-10

Family

ID=22195617

Family Applications (2)

Application Number Title Priority Date Filing Date
AT87307492T ATE78828T1 (de) 1986-08-27 1987-08-25 Verfahren und zwischenverbindungen fuer n-(s-3alkyl-heptanoyl)-d-gamma-glutamyl-glycyl-dalanine.
AT0262887A AT387380B (de) 1986-08-27 1987-10-08 Verfahren und zwischenprodukte fuer n-(s-3alkyl-heptanoyl)-d-gamma-glutamyl-glycyl-dalanin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT87307492T ATE78828T1 (de) 1986-08-27 1987-08-25 Verfahren und zwischenverbindungen fuer n-(s-3alkyl-heptanoyl)-d-gamma-glutamyl-glycyl-dalanine.

Country Status (11)

Country Link
EP (1) EP0258032B1 (de)
AT (2) ATE78828T1 (de)
AU (1) AU589543B2 (de)
DE (1) DE3780726T2 (de)
ES (1) ES2042572T3 (de)
FI (1) FI890885L (de)
GR (1) GR3005495T3 (de)
IE (1) IE60040B1 (de)
NO (1) NO881811L (de)
WO (1) WO1988001612A1 (de)
ZA (1) ZA876354B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1295784C (en) * 1985-11-25 1992-02-11 James Patrick Rizzi Peptide immunostimulants

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0060640A1 (de) * 1981-03-03 1982-09-22 Toray Industries, Inc. 5,6,7-Trinor-4,8-inter-m-phenylen-PGI-Derivate und ihre pharmazeutischen Zusammensetzungen

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US45475A (en) * 1864-12-20 Improved submarine port-hole
US3985722A (en) * 1973-12-12 1976-10-12 Ajinomoto Co., Inc. Process for preparing N-higher aliphatic acyl derivatives of amino acids, peptides or proteins
US4113968A (en) * 1974-10-03 1978-09-12 Kuraray Co., Ltd. Process for preparation of substituted cyclopropane carboxylic acids and esters thereof and intermediates of said acids and esters
US4374264A (en) * 1980-06-02 1983-02-15 Ici Australia Limited Process for the preparation of γ-unsaturated carboxylates
FR2496654A1 (fr) * 1980-12-19 1982-06-25 Rhone Poulenc Sante Nouveaux tri-, tetra- et pentapeptides, leur preparation et les medicaments qui les contiennent
US4565653A (en) * 1984-03-30 1986-01-21 Pfizer Inc. Acyltripeptide immunostimulants
WO1986001612A1 (fr) * 1984-08-29 1986-03-13 Optische Werke G. Rodenstock Systeme de projection pour un rayon de guidage
DE3665593D1 (en) * 1985-11-25 1989-10-19 Pfizer Peptide immunostimulants
WO1988001613A1 (en) * 1986-08-27 1988-03-10 Pfizer Inc. Crystalline n-(s-3-methylheptanoyl)-d-gamma-glutamyl-glycyl-d-alanine, and processes and intermediates therefor

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0060640A1 (de) * 1981-03-03 1982-09-22 Toray Industries, Inc. 5,6,7-Trinor-4,8-inter-m-phenylen-PGI-Derivate und ihre pharmazeutischen Zusammensetzungen

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEM. ABSTR. 100 *
CHEM. ABSTR. 91, 193003P *

Also Published As

Publication number Publication date
FI890885A7 (fi) 1989-02-24
FI890885A0 (fi) 1989-02-24
GR3005495T3 (de) 1993-05-24
NO881811D0 (no) 1988-04-26
ATE78828T1 (de) 1992-08-15
EP0258032B1 (de) 1992-07-29
IE60040B1 (en) 1994-05-18
AU7746287A (en) 1988-03-03
ES2042572T3 (es) 1993-12-16
ATA262887A (de) 1988-06-15
AU589543B2 (en) 1989-10-12
DE3780726T2 (de) 1992-12-17
DE3780726D1 (de) 1992-09-03
FI890885L (fi) 1989-02-24
EP0258032A3 (en) 1989-10-11
IE872278L (en) 1988-02-27
ZA876354B (en) 1989-03-29
WO1988001612A1 (en) 1988-03-10
NO881811L (no) 1988-04-26
EP0258032A2 (de) 1988-03-02

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Legal Events

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ELJ Ceased due to non-payment of the annual fee