ZA876354B - Process and intermediates for n-(s-3-alkylheptanoyl)-d-gamma-glutamyl-d-alanine - Google Patents

Process and intermediates for n-(s-3-alkylheptanoyl)-d-gamma-glutamyl-d-alanine

Info

Publication number
ZA876354B
ZA876354B ZA876354A ZA876354A ZA876354B ZA 876354 B ZA876354 B ZA 876354B ZA 876354 A ZA876354 A ZA 876354A ZA 876354 A ZA876354 A ZA 876354A ZA 876354 B ZA876354 B ZA 876354B
Authority
ZA
South Africa
Prior art keywords
alkylheptanoyl
glutamyl
alanine
gamma
intermediates
Prior art date
Application number
ZA876354A
Other languages
English (en)
Inventor
Charles William Murtiashaw
William Murtiashaw Charles
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA876354B publication Critical patent/ZA876354B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/62—Preparation of carboxylic acid halides by reactions not involving the carboxylic acid halide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/27—Preparation of carboxylic acid esters from ortho-esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/303—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/533—Monocarboxylic acid esters having only one carbon-to-carbon double bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA876354A 1986-08-27 1987-08-26 Process and intermediates for n-(s-3-alkylheptanoyl)-d-gamma-glutamyl-d-alanine ZA876354B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1986/001772 WO1988001612A1 (en) 1986-08-27 1986-08-27 Processes and intermediates for n-(s-3-alkyl-heptanoyl)-d-gamma-glutamyl-glycyl-d-alanine

Publications (1)

Publication Number Publication Date
ZA876354B true ZA876354B (en) 1989-03-29

Family

ID=22195617

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA876354A ZA876354B (en) 1986-08-27 1987-08-26 Process and intermediates for n-(s-3-alkylheptanoyl)-d-gamma-glutamyl-d-alanine

Country Status (11)

Country Link
EP (1) EP0258032B1 (xx)
AT (2) ATE78828T1 (xx)
AU (1) AU589543B2 (xx)
DE (1) DE3780726T2 (xx)
ES (1) ES2042572T3 (xx)
FI (1) FI890885A (xx)
GR (1) GR3005495T3 (xx)
IE (1) IE60040B1 (xx)
NO (1) NO881811L (xx)
WO (1) WO1988001612A1 (xx)
ZA (1) ZA876354B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1295784C (en) * 1985-11-25 1992-02-11 James Patrick Rizzi Peptide immunostimulants

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US45475A (en) * 1864-12-20 Improved submarine port-hole
US3985722A (en) * 1973-12-12 1976-10-12 Ajinomoto Co., Inc. Process for preparing N-higher aliphatic acyl derivatives of amino acids, peptides or proteins
US4113968A (en) * 1974-10-03 1978-09-12 Kuraray Co., Ltd. Process for preparation of substituted cyclopropane carboxylic acids and esters thereof and intermediates of said acids and esters
US4374264A (en) * 1980-06-02 1983-02-15 Ici Australia Limited Process for the preparation of γ-unsaturated carboxylates
FR2496654A1 (fr) * 1980-12-19 1982-06-25 Rhone Poulenc Sante Nouveaux tri-, tetra- et pentapeptides, leur preparation et les medicaments qui les contiennent
JPS57144276A (en) * 1981-03-03 1982-09-06 Toray Ind Inc 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative
US4565653A (en) * 1984-03-30 1986-01-21 Pfizer Inc. Acyltripeptide immunostimulants
EP0191079B1 (de) * 1984-08-29 1989-03-15 Optische Werke G. Rodenstock Projektionseinrichtung für einen leitstrahl
ATE46347T1 (de) * 1985-11-25 1989-09-15 Pfizer Immunostimulierende peptide.
WO1988001613A1 (en) * 1986-08-27 1988-03-10 Pfizer Inc. Crystalline n-(s-3-methylheptanoyl)-d-gamma-glutamyl-glycyl-d-alanine, and processes and intermediates therefor

Also Published As

Publication number Publication date
FI890885A0 (fi) 1989-02-24
EP0258032B1 (en) 1992-07-29
GR3005495T3 (xx) 1993-05-24
WO1988001612A1 (en) 1988-03-10
AU7746287A (en) 1988-03-03
EP0258032A3 (en) 1989-10-11
IE872278L (en) 1988-02-27
EP0258032A2 (en) 1988-03-02
NO881811D0 (no) 1988-04-26
ATA262887A (de) 1988-06-15
NO881811L (no) 1988-04-26
DE3780726D1 (de) 1992-09-03
AT387380B (de) 1989-01-10
ES2042572T3 (es) 1993-12-16
ATE78828T1 (de) 1992-08-15
DE3780726T2 (de) 1992-12-17
FI890885A (fi) 1989-02-24
IE60040B1 (en) 1994-05-18
AU589543B2 (en) 1989-10-12

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