ID18298A - Kompleks obat - Google Patents

Kompleks obat

Info

Publication number
ID18298A
ID18298A IDP971928A ID971928A ID18298A ID 18298 A ID18298 A ID 18298A ID P971928 A IDP971928 A ID P971928A ID 971928 A ID971928 A ID 971928A ID 18298 A ID18298 A ID 18298A
Authority
ID
Indonesia
Prior art keywords
spacer
complex
drug complex
drug
carboxy
Prior art date
Application number
IDP971928A
Other languages
English (en)
Inventor
Kazuhiro Inoue
Hiroshi Susaki
Masahiro Ikeda
Hiroshi Kuga
Eiji Kumazawa
Akiko Togo
Original Assignee
Daiichi Seiyaku Co
Drug Delivery System Inst Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co, Drug Delivery System Inst Ltd filed Critical Daiichi Seiyaku Co
Publication of ID18298A publication Critical patent/ID18298A/id

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
IDP971928A 1996-06-06 1997-06-05 Kompleks obat ID18298A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14442196 1996-06-06

Publications (1)

Publication Number Publication Date
ID18298A true ID18298A (id) 1998-03-26

Family

ID=15361795

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP971928A ID18298A (id) 1996-06-06 1997-06-05 Kompleks obat

Country Status (17)

Country Link
US (2) US6436912B1 (id)
EP (1) EP0916348B1 (id)
JP (1) JP4137183B2 (id)
KR (1) KR20000016558A (id)
CN (1) CN1227499A (id)
AT (1) ATE273715T1 (id)
AU (1) AU723392B2 (id)
CA (1) CA2257245A1 (id)
DE (1) DE69730332T2 (id)
DK (1) DK0916348T3 (id)
EA (1) EA001550B1 (id)
ES (1) ES2229354T3 (id)
ID (1) ID18298A (id)
NO (1) NO985666L (id)
PT (1) PT916348E (id)
TW (1) TW527183B (id)
WO (1) WO1997046260A1 (id)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH071238U (ja) * 1993-06-11 1995-01-10 株式会社大井製作所 ドアロック操作用のロッド連結装置
TW527183B (en) * 1996-06-06 2003-04-11 Daiichi Seiyaku Co Drug complex
TW409058B (en) 1996-06-06 2000-10-21 Daiichi Seiyaku Co Method for preparation of a drug complex
AU3733399A (en) * 1998-05-22 1999-12-13 Daiichi Pharmaceutical Co., Ltd. Drug composites
AU765409B2 (en) * 1998-10-30 2003-09-18 Daiichi Pharmaceutical Co., Ltd. DDS compounds and method for assaying the same
US6677456B2 (en) 1999-10-15 2004-01-13 Daiichi Pharmaceutical Co., Ltd. Pentacyclic taxan compound
DK1221445T3 (da) * 1999-10-15 2008-11-24 Daiichi Sankyo Co Ltd Pentacykliske taxanforbindelser
AU2001267831A1 (en) * 2000-06-29 2002-01-08 Daiichi Pharmaceutical Co., Ltd. DDS compound and process for the preparation thereof
BR0112417A (pt) * 2000-07-13 2003-07-01 Daiichi Seiyaku Co Composições farmacêuticas contendo composto dds
US20030092608A1 (en) * 2001-08-21 2003-05-15 Takayuki Kawaguchi Pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of malignant tumor
TWI313609B (en) * 2001-08-21 2009-08-21 Mitsubishi Tanabe Pharma Corp Pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of malignant tumor
TW200306314A (en) * 2002-04-16 2003-11-16 Tanabe Seiyaku Co Liquid preparation comprising camptothecin derivative and pharmaceutical composition producible by lyophilizing the preparation
AU2003288467A1 (en) * 2002-12-13 2004-07-09 Immunomedics, Inc. Immunoconjugates with an intracellularly-cleavable linkage
BR122018071968B8 (pt) 2003-11-06 2021-07-27 Seattle Genetics Inc conjugado de anticorpo-droga, composição farmacêutica, artigo de manufatura e uso de um conjugado de anticorpo-droga
CN101238142B (zh) * 2005-02-18 2012-11-14 国立大学法人德岛大学 含聚氧化烯链的脂质衍生物及含有该衍生物的脂质膜结构体
CN100516067C (zh) 2006-01-10 2009-07-22 上海恒瑞医药有限公司 具有抗肿瘤活性的紫杉酚衍生物
US9895449B2 (en) 2010-05-25 2018-02-20 Syndevrx, Inc. Polymer-conjugated MetAP2 inhibitors, and therapeutic methods of use thereof
WO2011150022A2 (en) 2010-05-25 2011-12-01 Syndevrx, Inc. Polymer-conjugated metap2 inhibitors, and therapeutic methods of use thereof
EP3632471A1 (en) 2012-10-11 2020-04-08 Daiichi Sankyo Company, Limited Antibody-drug conjugate
EP2910573B1 (en) 2012-10-19 2020-02-19 Daiichi Sankyo Company, Limited Antibody-drug conjugate produced by binding through linker having hydrophilic structure
DK2984085T3 (da) 2013-04-10 2019-10-21 Syndevrx Inc Modificerede eller polymerkonjugerede fumagillol metap2-hæmmere til anvendelse i behandling af fedme
WO2015071841A1 (en) 2013-11-12 2015-05-21 Druggability Technologies Holdings Limited Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them
KR102535900B1 (ko) 2013-12-25 2023-05-26 다이이찌 산쿄 가부시키가이샤 항 trop2 항체-약물 컨쥬게이트
SG10201800210TA (en) * 2014-01-31 2018-02-27 Daiichi Sankyo Co Ltd Anti-her2 antibody-drug conjugate
KR102127623B1 (ko) 2014-04-10 2020-06-29 다이이찌 산쿄 가부시키가이샤 항her3 항체-약물 콘주게이트
ES2754348T3 (es) * 2014-04-10 2020-04-17 Daiichi Sankyo Co Ltd Conjugado de (anticuerpo anti-HER2)-fármaco
EP4180455A1 (en) 2015-06-29 2023-05-17 Daiichi Sankyo Company, Limited Method for selectively manufacturing antibody-drug conjugate
KR20180093995A (ko) 2015-12-10 2018-08-22 신데브알엑스, 인크. 푸마길롤 유도체 및 그의 다형체
US10646463B2 (en) 2016-01-11 2020-05-12 Syndevrx, Inc. Treatment for tumors driven by metabolic dysfunction
AU2017341000A1 (en) 2016-10-07 2019-04-11 Daiichi Sankyo Company, Limited Therapy for drug-resistant cancer by administration of anti-HER2 antibody/drug conjugate
AU2017377233A1 (en) 2016-12-12 2019-06-13 Daiichi Sankyo Company, Limited Combination of antibody-drug conjugate and immune checkpoint inhibitor
AU2018210081A1 (en) 2017-01-17 2019-08-08 Daiichi Sankyo Company, Limited Anti-GPR20 antibody and anti-GPR20 antibody-drug conjugate
TW202330036A (zh) 2017-05-15 2023-08-01 日商第一三共股份有限公司 抗體-藥物結合物之製造方法
CN117838880A (zh) 2017-08-31 2024-04-09 第一三共株式会社 制备抗体-药物缀合物的新方法
SG11202000997YA (en) 2017-08-31 2020-03-30 Daiichi Sankyo Co Ltd Improved method for producing antibody-drug conjugate
DK3794042T3 (da) 2018-05-18 2024-04-15 Daiichi Sankyo Co Ltd Anti-muc1-exatecet-antistof-lægemiddelkonjugat
CN113453721A (zh) 2018-10-26 2021-09-28 辛德弗雷克斯公司 Metap2抑制剂的生物标志物及其应用
BR112022000297A2 (pt) 2019-07-10 2022-03-15 Cybrexa 3 Inc Conjugados de peptídeos de agentes de alvo de microtúbulos como terapêuticos
CN114341162A (zh) 2019-07-10 2022-04-12 赛博克萨2公司 作为治疗剂的细胞毒素的肽缀合物
US11806405B1 (en) 2021-07-19 2023-11-07 Zeno Management, Inc. Immunoconjugates and methods

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59220197A (ja) * 1983-05-30 1984-12-11 Snow Brand Milk Prod Co Ltd 新規な含窒素多糖体およびその製造方法
JP2604930B2 (ja) * 1990-12-14 1997-04-30 株式会社ディ・ディ・エス研究所 ヒアルロン酸およびコンドロイチン誘導体
CA2081025A1 (en) 1991-02-21 1992-08-22 Kazuhiro Inoue Carboxymethylmannoglucans and derivatives thereof
JP3359955B2 (ja) 1992-07-16 2002-12-24 第一製薬株式会社 抗腫瘍剤
DE69425464T2 (de) 1993-02-26 2001-05-23 Drug Delivery System Inst Ltd Polysaccharidderivat und wirkstoffträger
JPH0784481A (ja) 1993-06-26 1995-03-31 Ricoh Co Ltd 画像形成装置
US5811510A (en) * 1995-04-14 1998-09-22 General Hospital Corporation Biodegradable polyacetal polymers and methods for their formation and use
SG50747A1 (en) 1995-08-02 1998-07-20 Tanabe Seiyaku Co Comptothecin derivatives
TW527183B (en) * 1996-06-06 2003-04-11 Daiichi Seiyaku Co Drug complex
TW409058B (en) 1996-06-06 2000-10-21 Daiichi Seiyaku Co Method for preparation of a drug complex
AU3733399A (en) 1998-05-22 1999-12-13 Daiichi Pharmaceutical Co., Ltd. Drug composites
AU765409B2 (en) 1998-10-30 2003-09-18 Daiichi Pharmaceutical Co., Ltd. DDS compounds and method for assaying the same

Also Published As

Publication number Publication date
AU2978797A (en) 1998-01-05
NO985666L (no) 1999-02-04
DE69730332T2 (de) 2005-09-22
JP4137183B2 (ja) 2008-08-20
ES2229354T3 (es) 2005-04-16
US6436912B1 (en) 2002-08-20
CA2257245A1 (en) 1997-12-11
KR20000016558A (ko) 2000-03-25
TW527183B (en) 2003-04-11
CN1227499A (zh) 1999-09-01
US20030171262A1 (en) 2003-09-11
EP0916348A1 (en) 1999-05-19
DK0916348T3 (da) 2004-12-06
DE69730332D1 (de) 2004-09-23
ATE273715T1 (de) 2004-09-15
WO1997046260A1 (en) 1997-12-11
EA199900004A1 (ru) 1999-06-24
AU723392B2 (en) 2000-08-24
EA001550B1 (ru) 2001-04-23
EP0916348B1 (en) 2004-08-18
US6838450B2 (en) 2005-01-04
PT916348E (pt) 2004-10-29
NO985666D0 (no) 1998-12-04
EP0916348A4 (en) 2000-11-29

Similar Documents

Publication Publication Date Title
EA199900004A1 (ru) Лекарственный комплекс
NO301829B1 (no) 2-pyridylmetylenpolyazamakrocyklo-fosfonsyrer, komplekser og farmasöytiske preparater basert på disse
TW225532B (id)
CA2192944A1 (en) Stimulation of Hair Growth by Peptide-Copper Complexes
ATE244015T1 (de) Formulierungen fuer faktor ix
AU6701890A (en) Process for the production of biologically active protein
NL300106I1 (nl) N-terminaal chemisch gemodificeerde eiwitpreparaten en werkwijzen.
RU94017851A (ru) Ингибиторы протеолитических ферментов на основе производных сахарина, фармацевтическая композиция для лечения дегеративных заболеваний
NO302474B1 (no) Sakarinderivater, farmasöytisk sammensetning og anvendelse derav
ES2107033T3 (es) Peptidos bpc, su preparacion y su utilizacion.
DE69124705D1 (de) Hexapeptide als liganden des anaphylatoxin-rezeptors
RU92016453A (ru) Гидроксамовые кислоты и n-гидроксимочевины, способы их получения, фармацевтическая композиция и способ ингибирования липоксигеназы
DK0700898T3 (da) L-carnitinsalt og kosmetiske og farmaceutiske præparater indeholdende samme, til behandling af dermatoser.
HU912010D0 (en) Utilization of macroring amino-phosphonic acid complexes as transformation agents
MY131384A (en) Novel 2-saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof
IT8868117A0 (it) Solfonammidi di benzilidene canfora derivanti da amminoacidi e loro impiego in cosmesi particolarmente come filtri solari
DE69018275T2 (de) Peptide, deren Verwendung als Hemmer gegen Entwicklung von t-Lymphocyten und Wirksamkeit von Makrophagen und Verfahren zu deren Herstellung.
ATE91689T1 (de) Geminale bisphosphonsaeuren und deren derivate als antiarthritische mittel.
ATE164882T1 (de) Verfahren zur herstellung von aktivierten killer- monozyten und verfahren zur überprüfung ihrer tumoriziden aktivität
ATE36957T1 (de) N,n-diethyl-5-methyl-2h,1-benzothiopyrano-(4,3, - cd)-indazol-2-ethanamine, diese enthaltende zubereitungen und ihre verwendung.
ATE78828T1 (de) Verfahren und zwischenverbindungen fuer n-(s-3alkyl-heptanoyl)-d-gamma-glutamyl-glycyl-dalanine.
RU93048177A (ru) Новые 2-сахаринилметиларилкарбоксилаты, полезные в качестве ингибиторов протеолитических ферментов, и использование указанных соединений и композиция на их основе
ITMI922534A1 (it) Uso di acidi aril-, eteroaril- e alchiltartronici come agenti terapeutici
EP0239109A3 (en) Phosphonate angiotensin converting enzyme inhibitors
IT1248094B (it) Complessi costituiti da principi oftalmici basici ed acido tannico