BR0112417A - Composições farmacêuticas contendo composto dds - Google Patents
Composições farmacêuticas contendo composto ddsInfo
- Publication number
- BR0112417A BR0112417A BR0112417-0A BR0112417A BR0112417A BR 0112417 A BR0112417 A BR 0112417A BR 0112417 A BR0112417 A BR 0112417A BR 0112417 A BR0112417 A BR 0112417A
- Authority
- BR
- Brazil
- Prior art keywords
- compositions containing
- pharmaceutical compositions
- compound
- dds compound
- containing dds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
"COMPOSIçõES FARMACêUTICAS CONTENDO COMPOSTO DDS". Uma composição farmacêutica tendo estabilidade assegurada de preservação, a qual contém um composto, onde um derivado de polissacarídeos tendo um grupo de carboxila é ligado a um derivado de camptotecina através de um espaçador ou sem ser mediado por espaçador, e um açúcar ou álcool de açúcar opcionalmente juntamente com uma substância para ajuste de pH.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000213083 | 2000-07-13 | ||
PCT/JP2001/006020 WO2002005855A1 (fr) | 2000-07-13 | 2001-07-11 | Compositions pharmaceutiques contenant des composes dds |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0112417A true BR0112417A (pt) | 2003-07-01 |
Family
ID=18708899
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0112417-0A BR0112417A (pt) | 2000-07-13 | 2001-07-11 | Composições farmacêuticas contendo composto dds |
Country Status (12)
Country | Link |
---|---|
US (1) | US6815435B2 (pt) |
EP (1) | EP1308171A1 (pt) |
KR (1) | KR20030023697A (pt) |
CN (1) | CN1556712A (pt) |
AR (1) | AR031714A1 (pt) |
AU (1) | AU2001271037A1 (pt) |
BR (1) | BR0112417A (pt) |
CA (1) | CA2415922A1 (pt) |
MX (1) | MXPA03000387A (pt) |
NO (1) | NO20030139L (pt) |
RU (1) | RU2003100532A (pt) |
WO (1) | WO2002005855A1 (pt) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030031502A (ko) * | 2000-06-29 | 2003-04-21 | 다이이찌 세이야꾸 가부시기가이샤 | 디디에스 화합물 및 그의 제조방법 |
TWI320713B (pt) | 2001-06-01 | 2010-02-21 | Neochemir Inc | |
TW200306314A (en) * | 2002-04-16 | 2003-11-16 | Tanabe Seiyaku Co | Liquid preparation comprising camptothecin derivative and pharmaceutical composition producible by lyophilizing the preparation |
AU2003289234A1 (en) * | 2002-12-10 | 2004-06-30 | Masaya Tanaka | Skin material for external use and antiprutiric agent for external use and wrinkle-reducing instrument using the same |
TW200727900A (en) * | 2005-07-27 | 2007-08-01 | Yakult Honsha Kk | Aqueous solution preparation containing camptothecins |
JP5736031B2 (ja) | 2010-03-29 | 2015-06-17 | フェリング ベスローテン フェンノートシャップ | 速溶解性医薬組成物 |
AU2013263795B2 (en) * | 2010-03-29 | 2015-09-17 | Ferring B.V. | A fast dissolving pharmaceutical composition |
JO3112B1 (ar) | 2010-03-29 | 2017-09-20 | Ferring Bv | تركيبة دوائية سريعة التحلل |
AU2012307530B2 (en) * | 2011-09-16 | 2016-12-08 | Ferring B.V. | A fast dissolving pharmaceutical composition |
EP3632471A1 (en) | 2012-10-11 | 2020-04-08 | Daiichi Sankyo Company, Limited | Antibody-drug conjugate |
JP6272230B2 (ja) | 2012-10-19 | 2018-01-31 | 第一三共株式会社 | 親水性構造を含むリンカーで結合させた抗体−薬物コンジュゲート |
SI3088419T1 (sl) | 2013-12-25 | 2019-01-31 | Daiichi Sankyo Company | Zdravilni konjugat anti trop2 protitelesa |
KR20230162159A (ko) | 2014-01-31 | 2023-11-28 | 다이이찌 산쿄 가부시키가이샤 | 항-her2 항체-약물 접합체 |
EP3130608B1 (en) | 2014-04-10 | 2019-09-04 | Daiichi Sankyo Co., Ltd. | (anti-her2 antibody)-drug conjugate |
IL300540B1 (en) | 2014-04-10 | 2024-04-01 | Daiichi Sankyo Co Ltd | Preparation method for drug conjugates - antibody against - HER3 |
US9855339B2 (en) | 2014-12-26 | 2018-01-02 | Nippon Kayaku Kabushiki Kaisha | Pharmaceutical preparation of camptothecin-containing polymer derivative |
CN116059395A (zh) | 2015-06-29 | 2023-05-05 | 第一三共株式会社 | 用于选择性制造抗体-药物缀合物的方法 |
KR20180039628A (ko) * | 2015-09-03 | 2018-04-18 | 니폰 가야꾸 가부시끼가이샤 | 캄프토테신류 고분자 유도체를 함유하는 의약 조성물 |
KR20180114027A (ko) | 2016-03-01 | 2018-10-17 | 니폰 가야꾸 가부시끼가이샤 | 캄프토테신류 고분자 유도체를 함유하는 의약 제제 |
CA3046293A1 (en) | 2016-12-12 | 2018-06-21 | Daiichi Sankyo Company, Limited | Combination of antibody-drug conjugate and immune checkpoint inhibitor |
BR112019012847A2 (pt) | 2017-01-17 | 2019-12-10 | Daiichi Sankyo Co Ltd | anticorpo ou fragmento funcional do anticorpo, polinucleotídeo, vetor de expressão, células hospedeiras, método para produção de um anticorpo de interesse ou de um fragmento funcional do anticorpo e para produção de um conjugado de anticorpo-fármaco, conjugado de anticorpo-fármaco, composição farmacêutica, fármaco antitumoral, e, método de tratamento de um tumor. |
TW202330036A (zh) | 2017-05-15 | 2023-08-01 | 日商第一三共股份有限公司 | 抗體-藥物結合物之製造方法 |
BR112020003466B1 (pt) | 2017-08-31 | 2023-12-12 | Daiichi Sankyo Company, Limited | Métodos de produção de composto, e, composto |
AU2018327171B2 (en) | 2017-08-31 | 2023-03-09 | Daiichi Sankyo Company, Limited | Improved method for producing antibody-drug conjugate |
BR112020023373A2 (pt) | 2018-05-18 | 2021-02-09 | Daiichi Sankyo Company, Limited | conjugado, composição, e, uso de um conjugado ou de uma composição |
CN114341162A (zh) | 2019-07-10 | 2022-04-12 | 赛博克萨2公司 | 作为治疗剂的细胞毒素的肽缀合物 |
KR20220051332A (ko) | 2019-07-10 | 2022-04-26 | 싸이브렉사 3, 인크. | 치료제로서의 미세소관 표적화제의 펩티드 접합체 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5711909A (en) * | 1980-06-23 | 1982-01-21 | Shionogi & Co Ltd | Stable freeze-dried preparation of beta-lactam |
JPS61165322A (ja) * | 1985-01-14 | 1986-07-26 | Microbial Chem Res Found | スパガリン類の注射用凍結乾燥製剤 |
EP0857484A4 (en) | 1995-09-13 | 2000-12-06 | Nippon Shinyaku Co Ltd | PGE1- FREEZING DRIED PREPARATION AND METHOD FOR THE PRODUCTION THEREOF |
IL125800A0 (en) * | 1996-02-19 | 1999-04-11 | Nycomed Imaging As | Thermally stabilized contrast agent |
AU2034097A (en) * | 1996-03-19 | 1997-10-10 | Morgan Crucible Company Plc, The | A conduit |
JPH10212241A (ja) | 1996-05-27 | 1998-08-11 | Sumitomo Pharmaceut Co Ltd | Bdnfを安定に含有する製剤 |
TW527183B (en) * | 1996-06-06 | 2003-04-11 | Daiichi Seiyaku Co | Drug complex |
CA2345612A1 (en) | 1998-09-29 | 2000-04-06 | Masao Nagao | Anti-fungal composition |
-
2001
- 2001-07-11 BR BR0112417-0A patent/BR0112417A/pt not_active Application Discontinuation
- 2001-07-11 MX MXPA03000387A patent/MXPA03000387A/es not_active Application Discontinuation
- 2001-07-11 EP EP01949945A patent/EP1308171A1/en not_active Withdrawn
- 2001-07-11 US US10/332,706 patent/US6815435B2/en not_active Expired - Fee Related
- 2001-07-11 RU RU2003100532/15A patent/RU2003100532A/ru not_active Application Discontinuation
- 2001-07-11 KR KR10-2003-7000380A patent/KR20030023697A/ko not_active Application Discontinuation
- 2001-07-11 CN CNA018153607A patent/CN1556712A/zh active Pending
- 2001-07-11 WO PCT/JP2001/006020 patent/WO2002005855A1/ja active Application Filing
- 2001-07-11 AU AU2001271037A patent/AU2001271037A1/en not_active Abandoned
- 2001-07-11 CA CA002415922A patent/CA2415922A1/en not_active Abandoned
- 2001-07-12 AR ARP010103302A patent/AR031714A1/es unknown
-
2003
- 2003-01-10 NO NO20030139A patent/NO20030139L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2001271037A1 (en) | 2002-01-30 |
MXPA03000387A (es) | 2003-09-22 |
US6815435B2 (en) | 2004-11-09 |
EP1308171A1 (en) | 2003-05-07 |
NO20030139D0 (no) | 2003-01-10 |
WO2002005855A1 (fr) | 2002-01-24 |
NO20030139L (no) | 2003-03-13 |
US20030148931A1 (en) | 2003-08-07 |
RU2003100532A (ru) | 2004-07-20 |
CA2415922A1 (en) | 2002-01-24 |
CN1556712A (zh) | 2004-12-22 |
KR20030023697A (ko) | 2003-03-19 |
AR031714A1 (es) | 2003-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Ipc: A61K 31/4745 (2006.01), A61K 9/00 (2006.01), A61K |