NO333627B1 - Farmasoytisk preparat omfattende en 1,2-dihydropyridin-2-on forbindelse og et interferon, samt deres anvendelse ved behandling av demyeliniseringslidelser - Google Patents

Farmasoytisk preparat omfattende en 1,2-dihydropyridin-2-on forbindelse og et interferon, samt deres anvendelse ved behandling av demyeliniseringslidelser Download PDF

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Publication number
NO333627B1
NO333627B1 NO20042298A NO20042298A NO333627B1 NO 333627 B1 NO333627 B1 NO 333627B1 NO 20042298 A NO20042298 A NO 20042298A NO 20042298 A NO20042298 A NO 20042298A NO 333627 B1 NO333627 B1 NO 333627B1
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NO
Norway
Prior art keywords
dihydropyridin
pyridyl
compound
group
phenyl
Prior art date
Application number
NO20042298A
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English (en)
Norwegian (no)
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NO20042298L (no
Inventor
Terence Smith
Original Assignee
Eisai R&D Man Co Ltd
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Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of NO20042298L publication Critical patent/NO20042298L/no
Publication of NO333627B1 publication Critical patent/NO333627B1/no

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • A—HUMAN NECESSITIES
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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  • Pyridine Compounds (AREA)
NO20042298A 2001-12-06 2004-06-03 Farmasoytisk preparat omfattende en 1,2-dihydropyridin-2-on forbindelse og et interferon, samt deres anvendelse ved behandling av demyeliniseringslidelser NO333627B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0129260.6A GB0129260D0 (en) 2001-12-06 2001-12-06 Pharmaceutical compositions and their uses
PCT/GB2002/005542 WO2003047577A2 (en) 2001-12-06 2002-12-06 Pharmaceutical compositions comprising dihydropyridinone compounds and an immunoregulatory or an antiinflammatory agent and their uses

Publications (2)

Publication Number Publication Date
NO20042298L NO20042298L (no) 2004-09-06
NO333627B1 true NO333627B1 (no) 2013-07-29

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NO20042298A NO333627B1 (no) 2001-12-06 2004-06-03 Farmasoytisk preparat omfattende en 1,2-dihydropyridin-2-on forbindelse og et interferon, samt deres anvendelse ved behandling av demyeliniseringslidelser

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US (1) US7759367B2 (ru)
EP (1) EP1465626B1 (ru)
JP (1) JP4610898B2 (ru)
KR (1) KR100945822B1 (ru)
CN (1) CN1738618B (ru)
AT (1) ATE406893T1 (ru)
AU (1) AU2002347365B2 (ru)
BR (2) BR0214705A (ru)
CA (1) CA2469076C (ru)
CY (1) CY1108578T1 (ru)
DE (1) DE60228761D1 (ru)
DK (1) DK1465626T3 (ru)
ES (1) ES2311635T3 (ru)
GB (1) GB0129260D0 (ru)
HU (1) HU228328B1 (ru)
IL (2) IL162214A0 (ru)
MX (1) MXPA04005376A (ru)
NO (1) NO333627B1 (ru)
NZ (1) NZ533798A (ru)
PT (1) PT1465626E (ru)
RU (1) RU2358733C2 (ru)
SI (1) SI1465626T1 (ru)
WO (1) WO2003047577A2 (ru)
ZA (1) ZA200404330B (ru)

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EP1300396B1 (en) 2000-06-12 2009-01-14 Eisai R&D Management Co., Ltd. 1,2-dihydropyridine compounds, process for preparation of the same and use thereof
EP1430033A4 (en) 2001-08-31 2004-12-15 Univ Northwestern PROTEIN KINASE ANTI-INFLAMMATORY AND INHIBITOR COMPOSITION AND METHOD OF USE
TW200500341A (en) * 2002-11-12 2005-01-01 Astrazeneca Ab Novel compounds
US7189716B2 (en) * 2003-01-03 2007-03-13 Bristol-Myers Squibb Company Tyrosine kinase inhibitors
SE0302487D0 (sv) * 2003-09-18 2003-09-18 Astrazeneca Ab Novel compounds
SE0302486D0 (sv) 2003-09-18 2003-09-18 Astrazeneca Ab Novel compounds
JP4614884B2 (ja) * 2003-11-14 2011-01-19 シャンハイ ゲノミックス インク ピリドンの誘導体とその使用
GB0329498D0 (en) * 2003-12-19 2004-01-28 Novartis Ag Organic compounds
US7504403B2 (en) 2004-01-22 2009-03-17 Amgen Inc. Substituted heterocyclic compounds and methods of use
WO2005099688A2 (en) 2004-04-07 2005-10-27 Takeda Pharmaceutical Company Limited Cyclic compounds
MY148809A (en) * 2004-07-06 2013-05-31 Eisai R&D Man Co Ltd Crystals of 1,2-dihydropyridine compound and their production process
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