DE69634122D1 - Heterocyclische amidverbindungen und deren medizinische verwendung - Google Patents
Heterocyclische amidverbindungen und deren medizinische verwendungInfo
- Publication number
- DE69634122D1 DE69634122D1 DE69634122T DE69634122T DE69634122D1 DE 69634122 D1 DE69634122 D1 DE 69634122D1 DE 69634122 T DE69634122 T DE 69634122T DE 69634122 T DE69634122 T DE 69634122T DE 69634122 D1 DE69634122 D1 DE 69634122D1
- Authority
- DE
- Germany
- Prior art keywords
- medicine
- amide compounds
- heterocyclic amide
- heterocyclic
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/96—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10431495 | 1995-04-27 | ||
PCT/JP1996/001171 WO1996033974A1 (fr) | 1995-04-27 | 1996-04-26 | Composes heterocycliques amides et leur utilisation medicinale |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69634122D1 true DE69634122D1 (de) | 2005-02-03 |
Family
ID=14377479
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69634122T Expired - Lifetime DE69634122D1 (de) | 1995-04-27 | 1996-04-26 | Heterocyclische amidverbindungen und deren medizinische verwendung |
Country Status (7)
Country | Link |
---|---|
US (1) | US5948785A (de) |
EP (1) | EP0826671B1 (de) |
KR (1) | KR100400639B1 (de) |
CN (2) | CN1188401C (de) |
CA (1) | CA2219364A1 (de) |
DE (1) | DE69634122D1 (de) |
WO (1) | WO1996033974A1 (de) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU723234B2 (en) | 1996-09-06 | 2000-08-24 | Nippon Kayaku Kabushiki Kaisha | Novel acetamide derivatives and protease inhibitors |
US6063794A (en) | 1996-10-11 | 2000-05-16 | Cor Therapeutics Inc. | Selective factor Xa inhibitors |
US6262047B1 (en) | 1996-10-11 | 2001-07-17 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
US6194435B1 (en) | 1996-10-11 | 2001-02-27 | Cor Therapeutics, Inc. | Lactams as selective factor Xa inhibitors |
US6369080B2 (en) * | 1996-10-11 | 2002-04-09 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
WO1998018794A1 (fr) * | 1996-10-25 | 1998-05-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Nouveaux composes d'amide heterocycliques et leur utilisation a des fins medicinales |
JP2001508796A (ja) * | 1997-01-22 | 2001-07-03 | メルク エンド カンパニー インコーポレーテッド | トロンビン阻害薬 |
JP2001523226A (ja) | 1997-04-14 | 2001-11-20 | シーオーアール セラピューティクス インコーポレイテッド | 選択的Xa因子阻害剤 |
WO1998046627A1 (en) | 1997-04-14 | 1998-10-22 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
EP0975625A1 (de) | 1997-04-14 | 2000-02-02 | Cor Therapeutics, Inc. | AUSWÄHLEND Xa KAKTOR INHIBITOREN |
US6218382B1 (en) | 1997-08-11 | 2001-04-17 | Cor Therapeutics, Inc | Selective factor Xa inhibitors |
US6228854B1 (en) | 1997-08-11 | 2001-05-08 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
US6333321B1 (en) | 1997-08-11 | 2001-12-25 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
AU1684999A (en) * | 1997-12-22 | 1999-07-12 | Yoshitomi Pharmaceutical Industries, Ltd. | Chymase inhibitors |
AU744739B2 (en) * | 1998-02-17 | 2002-02-28 | Nippon Kayaku Kabushiki Kaisha | Novel acetamide derivative and use thereof |
US6528514B1 (en) * | 1998-03-11 | 2003-03-04 | Welfide Corporation | IgE antibody production inhibitors and autoimmune diseases inhibitors |
WO2000003997A1 (fr) * | 1998-07-15 | 2000-01-27 | Teijin Limited | Derives de thiobenzimidazole |
US20050267148A1 (en) * | 1998-07-15 | 2005-12-01 | Teijin Limited | Benzimidazole derivative |
KR20010074838A (ko) * | 1998-08-20 | 2001-08-09 | 요시다 쇼지 | 안 순환 장해의 예방 또는 치료제 |
US6750342B1 (en) | 1999-05-19 | 2004-06-15 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade |
EA004867B1 (ru) * | 1999-05-19 | 2004-08-26 | Фармация Корпорейшн | Замещенные пиримидиноновые соединения, композиция и способ лечения, ингибирования или предупреждения тромботических состояний у млекопитающих |
US6867217B1 (en) | 1999-05-19 | 2005-03-15 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade |
US6716838B1 (en) | 1999-05-19 | 2004-04-06 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl uracils as anticoagulative agents |
US7015230B1 (en) | 1999-05-19 | 2006-03-21 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade |
US6458952B1 (en) | 1999-05-19 | 2002-10-01 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade |
US6653316B1 (en) | 1999-05-19 | 2003-11-25 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade |
US6664255B1 (en) | 1999-05-19 | 2003-12-16 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade |
JP4556371B2 (ja) * | 1999-09-30 | 2010-10-06 | 三菱化学株式会社 | アシルスルホンアミド誘導体 |
AU7954900A (en) * | 1999-10-25 | 2001-05-08 | Senju Pharmaceutical Co., Ltd. | Tension-relieving agents for ciliary muscle |
CN1335778A (zh) | 1999-11-01 | 2002-02-13 | 三得利株式会社 | 含有糜蛋白酶抑制物质的血管脂质沉积抑制剂 |
CA2368366A1 (en) | 2000-02-22 | 2001-08-30 | Suntory Limited | Medicament for prevention or treatment of fibrosis having chymase inhibitor as effective ingredient |
AU3413501A (en) | 2000-02-22 | 2001-09-03 | Daiichi Asubio Pharma Co., Ltd. | Preventive or therapeutic drugs for various eosinophilia-related diseases containing chymase inhibitors as the active ingredient |
KR20010109356A (ko) | 2000-02-22 | 2001-12-08 | 도리이 신이치로 | 키마제 억제제를 유효성분으로 함유하는 피부염의 예방또는 치료제 |
WO2001068605A1 (en) | 2000-03-13 | 2001-09-20 | Pharmacia Corporation | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade |
US6693121B2 (en) | 2000-04-05 | 2004-02-17 | Pharmacia Corporation | Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the coagulation cascade |
US20020022604A1 (en) | 2000-04-05 | 2002-02-21 | South Michael S. | Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade |
EP1274676A2 (de) | 2000-04-17 | 2003-01-15 | Pharmacia Corporation | Polycyclische aryl- und heteroaryl- substuierte 1,4-chinone zur selektiven hemmung des blutgerinnungsprozesses |
WO2001087851A1 (en) * | 2000-05-18 | 2001-11-22 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade |
ES2320973T3 (es) * | 2000-06-12 | 2009-06-01 | EISAI R&D MANAGEMENT CO., LTD. | Compuestos de 1,2-dihidropiridina, procedimiento para su preparacion y uso de los mismos. |
US6943173B2 (en) * | 2000-07-18 | 2005-09-13 | Neurogen Corporation | 5-substituted 2-aryl-4-pyrimidinones |
CA2430037A1 (en) | 2000-11-20 | 2002-05-30 | Michael S. South | Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade |
US7015223B1 (en) | 2000-11-20 | 2006-03-21 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl 1,2,4-triazinones useful for selective inhibition of the coagulation cascade |
US7119094B1 (en) | 2000-11-20 | 2006-10-10 | Warner-Lambert Company | Substituted polycyclic aryl and heteroarpyl pyrazinones useful for selective inhibition of the coagulation cascade |
HUP0303631A2 (hu) * | 2000-12-26 | 2004-03-01 | Ono Pharmaceutical Co., Ltd. | Pirimidinszármazékok és eljárás előállításukra |
WO2003007964A1 (fr) * | 2001-07-18 | 2003-01-30 | Nippon Kayaku Kabushiki Kaisha | Remede ou agent preventif de cardiopathie ou d'anevrysme contenant un compose d'inhibition de la chymase |
US7105559B2 (en) | 2001-10-03 | 2006-09-12 | Pharmacia Corporation | Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade |
EP1438292A1 (de) | 2001-10-03 | 2004-07-21 | Pharmacia Corporation | 6-gliedrige heterocyclische verbindungen, die sich zur selektiven inhibierung der koagulationskaskade eignen |
GB0129260D0 (en) | 2001-12-06 | 2002-01-23 | Eisai London Res Lab Ltd | Pharmaceutical compositions and their uses |
EP1553090A4 (de) * | 2002-06-14 | 2006-07-05 | Ajinomoto Kk | Verfahren zur herstellung einer pyrimidinverbindung |
AU2003259261B2 (en) * | 2002-07-30 | 2005-11-24 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Use of chymase inhibitors for the prevention and/or treatment of arterio-venous graft failure |
PE20050159A1 (es) * | 2003-05-27 | 2005-04-19 | Vertex Pharma | Derivados de acido 3-[2-(3-amino-2-oxo-2h-piridin-1-il)-acetilamino]-4-oxo-pentanoico como inhibidores de caspasa |
AU2004266536A1 (en) * | 2003-08-22 | 2005-03-03 | Teijin Pharma Limited | Drug containing chymase inhibitor as the active ingredient |
EP1695967A1 (de) * | 2003-11-04 | 2006-08-30 | Ajinomoto Co., Inc. | Verfahren zur herstellung von pyrimidinderivaten und zwischenprodukten |
EP1529778A1 (de) * | 2003-11-04 | 2005-05-11 | Ajinomoto Co., Inc. | Verfahren zu Herstellung von Pyrimidin- Derivat, Zwischenprodukt dafür |
EP1533306A1 (de) * | 2003-11-04 | 2005-05-25 | Ajinomoto Co., Inc. | Azlactone und Verfahren zu deren Herstellung |
MY148809A (en) | 2004-07-06 | 2013-05-31 | Eisai R&D Man Co Ltd | Crystals of 1,2-dihydropyridine compound and their production process |
RU2412936C2 (ru) | 2004-11-24 | 2011-02-27 | Вертекс Фармасьютикалз Инкорпорейтед | Производные 3-[2-(3-ациламино-2-оксо-2н-пиридин-1-ил)-ацетиламино]-4-оксо-пентановой кислоты и их применение в качестве ингибиторов каспазы |
AR059898A1 (es) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2 |
TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
BRPI0816767B8 (pt) | 2007-09-14 | 2021-05-25 | Addex Pharmaceuticals Sa | composto 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridi¬nil-2'-onas 1',3'-dissubstituídas, composição farmacêutica e uso dos mesmos |
ES2439291T3 (es) | 2008-09-02 | 2014-01-22 | Janssen Pharmaceuticals, Inc. | Derivados de 3-azabiciclo[3.1.0]hexilo como moduladores de receptores de glutamato metabotrópicos |
WO2010060589A1 (en) | 2008-11-28 | 2010-06-03 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
WO2010088195A1 (en) | 2009-01-30 | 2010-08-05 | Boehringer Ingelheim International Gmbh | Azaquinazolinediones useful as chymase inhibitors |
CN102439008B (zh) | 2009-05-12 | 2015-04-29 | 杨森制药有限公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途 |
NZ596053A (en) | 2009-05-12 | 2013-05-31 | Janssen Pharmaceuticals Inc | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
MX2012002973A (es) * | 2009-09-09 | 2012-04-19 | Du Pont | Derivados de pirimidona herbicidas. |
US9271967B2 (en) | 2010-11-08 | 2016-03-01 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
ES2536433T3 (es) | 2010-11-08 | 2015-05-25 | Janssen Pharmaceuticals, Inc. | Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2 |
US8993591B2 (en) | 2010-11-08 | 2015-03-31 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a] pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors |
JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
US9695131B2 (en) | 2013-11-08 | 2017-07-04 | Bayer Pharma Aktiengesellschaft | Substituted uracils as chymase inhibitors |
DK3096790T3 (da) | 2014-01-21 | 2019-10-07 | Janssen Pharmaceutica Nv | Kombinationer omfattende positive allosteriske modulatorer eller orthosteriske agonister af metabotrop glutamaterg subtype 2-receptor og anvendelse af disse |
DK3431106T3 (da) | 2014-01-21 | 2021-03-15 | Janssen Pharmaceutica Nv | Kombinationer omfattende positive allosteriske modulatorer eller orthosteriske agonister af metabotrop glutamaterg subtype 2-receptor og anvendelse af disse |
WO2016039936A2 (en) * | 2014-09-09 | 2016-03-17 | Ptc Therapeutics, Inc. | Monocyclic substituted 2-pyridinone antibacterial compounds |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9207145D0 (en) * | 1991-04-18 | 1992-05-13 | Ici Plc | Heterocyclic amides |
GB9216272D0 (en) * | 1991-08-15 | 1992-09-09 | Ici Plc | Substituted heterocycles |
US5441960A (en) * | 1992-04-16 | 1995-08-15 | Zeneca Limited | 1-pyrimidinylacetamide human leukocyte elastate inhibitors |
GB9307555D0 (en) * | 1992-04-16 | 1993-06-02 | Zeneca Ltd | Heterocyclic compounds |
US5486529A (en) * | 1992-04-16 | 1996-01-23 | Zeneca Limited | Certain pyridyl ketones for treating diseases involving leukocyte elastase |
AU703451B2 (en) * | 1994-03-31 | 1999-03-25 | Vertex Pharmaceuticals Incorporated | N-(pyrimidinyl)-aspartic acid analogs as interleukin-1beta converting enzyme inhibitors |
-
1996
- 1996-04-26 EP EP96912273A patent/EP0826671B1/de not_active Expired - Lifetime
- 1996-04-26 CA CA002219364A patent/CA2219364A1/en not_active Abandoned
- 1996-04-26 KR KR1019970707522A patent/KR100400639B1/ko not_active IP Right Cessation
- 1996-04-26 DE DE69634122T patent/DE69634122D1/de not_active Expired - Lifetime
- 1996-04-26 CN CNB001217976A patent/CN1188401C/zh not_active Expired - Fee Related
- 1996-04-26 CN CN96194926A patent/CN1131210C/zh not_active Expired - Fee Related
- 1996-04-26 WO PCT/JP1996/001171 patent/WO1996033974A1/ja active IP Right Grant
- 1996-04-26 US US08/952,319 patent/US5948785A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0826671A1 (de) | 1998-03-04 |
CN1304931A (zh) | 2001-07-25 |
CA2219364A1 (en) | 1996-10-31 |
CN1188472A (zh) | 1998-07-22 |
WO1996033974A1 (fr) | 1996-10-31 |
KR19990007998A (ko) | 1999-01-25 |
US5948785A (en) | 1999-09-07 |
KR100400639B1 (ko) | 2003-12-31 |
CN1131210C (zh) | 2003-12-17 |
EP0826671A4 (de) | 1998-09-02 |
EP0826671B1 (de) | 2004-12-29 |
CN1188401C (zh) | 2005-02-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69634122D1 (de) | Heterocyclische amidverbindungen und deren medizinische verwendung | |
DE69424853D1 (de) | Morphinan-derivate und ihre medizinische verwendung | |
ATE205185T1 (de) | Benzamid-derivate und deren verwendung als vasopressin-antagonisten | |
DE69622148D1 (de) | Chinazozin derivate und deren verwendung | |
DE69425905T2 (de) | Spinndüse und deren Verwendung | |
DE69631240D1 (de) | Schaltvorrichtung und deren verwendung | |
DE69123915D1 (de) | Indol-Verbindungen und deren Verwendung | |
DE59802439D1 (de) | Spiroverbindungen und deren verwendung | |
DE59711847D1 (de) | Substituierte aza- und diazacycloheptan- und -cyclooctanverbindungen und deren verwendung | |
DE69223266D1 (de) | Peptidderivate und deren Verwendung | |
DE69620270D1 (de) | Backfett und dessen Verwendung | |
ATE186447T1 (de) | Zusammensetzung und verwendung | |
DE69632678D1 (de) | Harzzusammensetzung und deren verwendung | |
DE59603788D1 (de) | 1-fluorisochinolinderivate und ihre verwendung in flüssigkristallinen mischungen | |
DE69713512D1 (de) | Substituierte phtalocyanine und deren verwendung | |
DE59603790D1 (de) | Trifluortetrahydroisochinolin-derivate und ihre verwendung in flüssigkristallinen mischungen | |
DE69600829T2 (de) | Mikrobizide Zusammensetzung und deren Verwendung | |
DE59603287D1 (de) | 1-fluor-5,6,7,8-tetrahydroisochinolin-derivate und ihre verwendung in flüssigkristallinen mischungen | |
DE69631632D1 (de) | Schaltvorrichtung und deren verwendung | |
DE59806523D1 (de) | Substituierte heterocyclische Benzocycloalkene und ihre Verwendung als analgetisch wirksame Substanzen | |
DE69304538D1 (de) | Aminosäure-derivate und deren verwendung | |
DE69521174D1 (de) | Anthrachinonderivate mit antitumorwirkung und ihre verwendung | |
DE69736972D1 (de) | Raffinose-Synthetase-Gene und deren Verwendung | |
DE59606922D1 (de) | Difluorphenylpyrimidylpyridin-derivate und ihre verwendung in flüssigkristallinen mischungen | |
DE69328467T2 (de) | Polyamidzusammensetzung und Verwendung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |