DE69622148T2 - Chinazozin derivate und deren verwendung - Google Patents
Chinazozin derivate und deren verwendungInfo
- Publication number
- DE69622148T2 DE69622148T2 DE69622148T DE69622148T DE69622148T2 DE 69622148 T2 DE69622148 T2 DE 69622148T2 DE 69622148 T DE69622148 T DE 69622148T DE 69622148 T DE69622148 T DE 69622148T DE 69622148 T2 DE69622148 T2 DE 69622148T2
- Authority
- DE
- Germany
- Prior art keywords
- chinazozine
- derivatives
- chinazozine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
- C07F9/65128—Six-membered rings having the nitrogen atoms in positions 1 and 3 condensed with carbocyclic rings or carbocyclic ring systems
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28543795 | 1995-09-28 | ||
| JP11655796 | 1996-05-10 | ||
| PCT/JP1996/002830 WO1997011941A1 (en) | 1995-09-28 | 1996-09-27 | Quinazoline derivatives and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69622148D1 DE69622148D1 (de) | 2002-08-08 |
| DE69622148T2 true DE69622148T2 (de) | 2002-10-31 |
Family
ID=26454863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69622148T Expired - Fee Related DE69622148T2 (de) | 1995-09-28 | 1996-09-27 | Chinazozin derivate und deren verwendung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5814631A (de) |
| EP (1) | EP0795548B1 (de) |
| JP (1) | JP3992291B2 (de) |
| DE (1) | DE69622148T2 (de) |
| ES (1) | ES2175127T3 (de) |
| WO (1) | WO1997011941A1 (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000003997A1 (fr) | 1998-07-15 | 2000-01-27 | Teijin Limited | Derives de thiobenzimidazole |
| US20050267148A1 (en) * | 1998-07-15 | 2005-12-01 | Teijin Limited | Benzimidazole derivative |
| WO2000010605A2 (fr) * | 1998-08-20 | 2000-03-02 | Senju Pharmaceutical Co., Ltd. | Prophylaxie ou remedes pour la perturbation circulatoire de l'oeil |
| JP2002523404A (ja) * | 1998-08-21 | 2002-07-30 | サントリー株式会社 | キナゾリン誘導体およびその用途 |
| EP1136488A4 (de) * | 1998-12-01 | 2002-06-12 | Meiji Seika Kaisha | Sf2809-i, ii, iii. vi, v und vi-verbindungen mit chymase-inhibierender wirkung |
| JP4556371B2 (ja) * | 1999-09-30 | 2010-10-06 | 三菱化学株式会社 | アシルスルホンアミド誘導体 |
| JP4491866B2 (ja) * | 1999-09-30 | 2010-06-30 | 三菱化学株式会社 | アシルスルホンアミド誘導体 |
| ATE360423T1 (de) * | 1999-11-01 | 2007-05-15 | Daiichi Asubio Pharma Co Ltd | Verwendung von chymase hemmern gegen vaskuläre lipidablagerung |
| EP1174151B1 (de) | 2000-02-22 | 2007-01-24 | Daiichi Asubio Pharma Co., Ltd. | Therapeutische behandlung von eosinophilie durch verwendung von chymase-inhibitoren als aktiven bestandteilen |
| US6500835B2 (en) | 2000-02-22 | 2002-12-31 | Suntory Limited | Preventive or therapeutic drugs for fibrosis containing chymase inhibitors as the active ingredient |
| DE60121695T2 (de) * | 2000-02-22 | 2007-08-30 | Daiichi Asubio Pharma Co., Ltd. | Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen |
| AU2001288053A1 (en) * | 2000-09-18 | 2002-03-26 | Toa Eiyo Ltd. | N-substituted benzothiophenesulfonamide derivatives |
| US7071220B2 (en) | 2000-09-18 | 2006-07-04 | Toa Eiyo Ltd. | N-substituted benzothiophenesulfonamide derivatives |
| CA2442761A1 (en) * | 2001-08-24 | 2003-03-06 | Teijin Limited | Drugs comprising chymase inhibitors and ace inhibitors as effective ingredients |
| WO2003078419A1 (en) * | 2002-03-15 | 2003-09-25 | Toa Eiyo Ltd. | N-substituted benzothiophenesulfonamide derivative |
| EP1539171A4 (de) * | 2002-07-30 | 2007-12-19 | Sod Conseils Rech Applic | Verwendung von chymase-hemmern zur prävention und/oder behandlung von arterio-venösem implantatversagen |
| JP5010917B2 (ja) * | 2003-08-29 | 2012-08-29 | エグゼリクシス， インコーポレイテッド | ｃ−Ｋｉｔ調節因子および使用方法 |
| US7361767B2 (en) * | 2003-11-14 | 2008-04-22 | 3M Innovative Properties Company | N-sulfonyldicarboximide containing tethering compounds |
| US7423155B2 (en) | 2003-11-14 | 2008-09-09 | 3M Innovative Properties Company | N-sulfonyldicarboximide containing tethering compounds |
| NZ554374A (en) * | 2004-10-07 | 2010-11-26 | Vitae Pharmaceuticals Inc | Diaminoalkane aspartic protease inhibitors |
| US7544756B2 (en) | 2005-09-30 | 2009-06-09 | 3M Innovative Properties Company | Crosslinked polymers with amine binding groups |
| EP1956907A2 (de) * | 2005-11-25 | 2008-08-20 | Basf Se | Cyanobenzolverbindungen für die bekämpfung von tierischen schädlingen |
| EP2001875A2 (de) * | 2006-03-08 | 2008-12-17 | Takeda San Diego, Inc. | Glucokinase-aktivatoren |
| US7705034B2 (en) * | 2006-10-13 | 2010-04-27 | Hoffmann-La Roche Inc. | Vinylogous acid derivatives |
| EP2188277B1 (de) * | 2007-08-16 | 2012-11-21 | Boehringer Ingelheim International GmbH | Chinazolindionchymasehemmer |
| EP2391624B1 (de) | 2009-01-30 | 2013-01-16 | Boehringer Ingelheim International GmbH | Als chymaseinhibitoren geeignete azachinazolindione |
| CN103443085B (zh) | 2011-03-14 | 2016-03-23 | 南京英派药业有限公司 | 喹唑啉二酮及其应用 |
| TWI527800B (zh) | 2011-04-01 | 2016-04-01 | 南京英派藥業有限公司 | 作為聚（二磷酸腺苷酸－核醣）聚合酶（ｐａｒｐ）之抑制劑之１－（芳基甲基）喹唑啉－２，４（１ｈ，３ｈ）－二酮及其應用 |
| ES2834959T3 (es) | 2012-12-06 | 2021-06-21 | Celgene Quanticel Res Inc | Inhibidores de histona desmetilasa |
| MA56473A (fr) | 2015-02-16 | 2022-05-11 | The Provost Fellows Found Scholars And The Other Members Of Board Of The College Of The Holy & Undiv | Sulfonylurées, composés apparentés, et leur utilisation |
| US11840543B2 (en) | 2017-05-24 | 2023-12-12 | The University Of Queensland | Compounds and uses |
| WO2019008029A1 (en) * | 2017-07-07 | 2019-01-10 | Inflazome Limited | SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3 |
| RS62910B1 (sr) | 2017-07-07 | 2022-03-31 | Inflazome Ltd | Nova jedinjenja sulfonamid karboksamida |
| MA49903A (fr) | 2017-08-15 | 2020-06-24 | Inflazome Ltd | Sulfonylureés et sulfonylthioureés en tant qu'inhibiteurs de nlrp3 |
| US11542255B2 (en) | 2017-08-15 | 2023-01-03 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| US11926600B2 (en) | 2017-08-15 | 2024-03-12 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| CN111094267B (zh) * | 2017-09-30 | 2022-06-14 | 正大天晴药业集团股份有限公司 | 作为RORγ抑制剂的磺酰基取代的双环化合物 |
| EP3759077A1 (de) | 2018-03-02 | 2021-01-06 | Inflazome Limited | Neuartige verbindungen |
| US11077101B1 (en) * | 2018-07-18 | 2021-08-03 | Tango Therapeutics, Inc. | Compounds and methods of use |
| KR20230094196A (ko) | 2020-07-31 | 2023-06-27 | 탱고 테라퓨틱스, 인크. | Mtap-결핍 및/또는 mta 축적 암의 치료에 유용한 피페리딘-1-일-n-피리딘-3-일-2-옥소아세트아마이드 유도체 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4684654A (en) * | 1985-08-14 | 1987-08-04 | American Cyanamid Company | 3-heteroalkyl-2,4-quinzaolinediones |
| IL79249A (en) * | 1986-06-26 | 1992-02-16 | Makhteshim Chem Works Ltd | Herbicidal compositions containing haloalkylthioquinazoline di(thi)ones and some new such compounds |
-
1996
- 1996-09-27 JP JP51329697A patent/JP3992291B2/ja not_active Expired - Fee Related
- 1996-09-27 ES ES96932039T patent/ES2175127T3/es not_active Expired - Lifetime
- 1996-09-27 EP EP96932039A patent/EP0795548B1/de not_active Expired - Lifetime
- 1996-09-27 DE DE69622148T patent/DE69622148T2/de not_active Expired - Fee Related
- 1996-09-27 WO PCT/JP1996/002830 patent/WO1997011941A1/ja active IP Right Grant
- 1996-09-27 US US08/849,114 patent/US5814631A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP3992291B2 (ja) | 2007-10-17 |
| EP0795548A4 (de) | 1998-09-02 |
| ES2175127T3 (es) | 2002-11-16 |
| EP0795548B1 (de) | 2002-07-03 |
| US5814631A (en) | 1998-09-29 |
| EP0795548A1 (de) | 1997-09-17 |
| DE69622148D1 (de) | 2002-08-08 |
| WO1997011941A1 (en) | 1997-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: DAICHI SUNTORY PHARMA CO., LTD., TOKIO/TOKYO, JP |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: DAIICHI ASUBIO PHARMA CO., LTD., TOKIO/TOKYO, JP |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: ASUBIO PHARMA CO., LTD., TOKYO, JP |
|
| 8339 | Ceased/non-payment of the annual fee |