ATE360423T1 - Verwendung von chymase hemmern gegen vaskuläre lipidablagerung - Google Patents

Verwendung von chymase hemmern gegen vaskuläre lipidablagerung

Info

Publication number
ATE360423T1
ATE360423T1 AT00971729T AT00971729T ATE360423T1 AT E360423 T1 ATE360423 T1 AT E360423T1 AT 00971729 T AT00971729 T AT 00971729T AT 00971729 T AT00971729 T AT 00971729T AT E360423 T1 ATE360423 T1 AT E360423T1
Authority
AT
Austria
Prior art keywords
inhibitors against
against vascular
chymase inhibitors
lipid deposit
vascular lipid
Prior art date
Application number
AT00971729T
Other languages
English (en)
Inventor
Harukazu Fukami
Hidenori Urata
Original Assignee
Daiichi Asubio Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Asubio Pharma Co Ltd filed Critical Daiichi Asubio Pharma Co Ltd
Application granted granted Critical
Publication of ATE360423T1 publication Critical patent/ATE360423T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT00971729T 1999-11-01 2000-11-01 Verwendung von chymase hemmern gegen vaskuläre lipidablagerung ATE360423T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP31125799 1999-11-01

Publications (1)

Publication Number Publication Date
ATE360423T1 true ATE360423T1 (de) 2007-05-15

Family

ID=18014979

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00971729T ATE360423T1 (de) 1999-11-01 2000-11-01 Verwendung von chymase hemmern gegen vaskuläre lipidablagerung

Country Status (11)

Country Link
US (1) US6921766B1 (de)
EP (1) EP1142586B1 (de)
KR (1) KR20010100004A (de)
CN (1) CN1335778A (de)
AT (1) ATE360423T1 (de)
AU (1) AU784467B2 (de)
CA (1) CA2358314A1 (de)
DE (1) DE60034545T2 (de)
ES (1) ES2281358T3 (de)
HU (1) HUP0104952A3 (de)
WO (1) WO2001032214A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1174151B1 (de) 2000-02-22 2007-01-24 Daiichi Asubio Pharma Co., Ltd. Therapeutische behandlung von eosinophilie durch verwendung von chymase-inhibitoren als aktiven bestandteilen
DE60121695T2 (de) 2000-02-22 2007-08-30 Daiichi Asubio Pharma Co., Ltd. Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen
CA2368366A1 (en) 2000-02-22 2001-08-30 Suntory Limited Medicament for prevention or treatment of fibrosis having chymase inhibitor as effective ingredient
WO2003007964A1 (fr) * 2001-07-18 2003-01-30 Nippon Kayaku Kabushiki Kaisha Remede ou agent preventif de cardiopathie ou d'anevrysme contenant un compose d'inhibition de la chymase
US20060276455A1 (en) * 2003-02-13 2006-12-07 Lindsberg Perttu J Use of a mast cell activation or degranulation blocking agent in the manufacture of a medicament for the treatment of cerebral ischemia
US7888348B2 (en) 2004-12-02 2011-02-15 Daiichi Sankyo Company, Limited 7-membered ring compound and method of production and pharmaceutical application thereof
KR20090023583A (ko) 2006-05-31 2009-03-05 아스비오파마 가부시키가이샤 7원환 화합물, 그의 제조법 및 의약 용도
JP5291124B2 (ja) * 2008-01-30 2013-09-18 シン・プーン・ファーマシューティカル・カンパニー・リミテッド 新規なキナゾリン−２，４−ジオン誘導体、及びこれを含有する脳神経系疾患の予防及び治療用医薬組成物
JP6364362B2 (ja) * 2015-02-17 2018-07-25 学校法人福岡大学 ヒトキマーゼ阻害剤および機能性食品、並びにヒトキマーゼの活性を阻害する方法
JP7072586B2 (ja) 2017-05-24 2022-05-20 ザ ユニバーシティ オブ クィーンズランド 新規な化合物及び使用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5199279A (en) 1991-08-13 1993-04-06 Reynolds Martin M Drum contact freezer system and method
JP2982454B2 (ja) 1991-12-20 1999-11-22 王子製紙株式会社 感熱記録体
EP0644892A1 (de) 1992-06-12 1995-03-29 Pfizer Inc. Inhibitoren für Angiotensin I-Chymasen inklusive der menschlichen Herzchymase
WO1996004248A1 (fr) 1994-07-29 1996-02-15 Suntory Limited Derives d'imidazolidine et son utilisation
US5948785A (en) * 1995-04-27 1999-09-07 The Green Cross Corporation Heterocyclic amide compounds and pharmaceutical use of the same
US5596111A (en) 1995-06-05 1997-01-21 North Dakota State University Method for preparation of carboxylic acids
WO1997011941A1 (en) 1995-09-28 1997-04-03 Suntory Limited Quinazoline derivatives and use thereof
EP0906273B1 (de) 1996-05-24 2002-10-16 Neurosearch A/S Saure gruppen enthaltende phenylderivate, ihre herstellung und ihre verwendung als chloridkanalblocker
AUPO062696A0 (en) * 1996-06-24 1996-07-18 Fujisawa Pharmaceutical Co., Ltd. Novel compounds
EP0940400A4 (de) 1996-10-25 2002-10-02 Mitsubishi Pharma Corp Heterocyklische amidverbindungen und ihre medizinische anwendung
AU744739B2 (en) 1998-02-17 2002-02-28 Nippon Kayaku Kabushiki Kaisha Novel acetamide derivative and use thereof
HUP0103387A3 (en) * 1998-08-21 2002-07-29 Daiichi Asubio Pharma Co Ltd Quinazoline derivatives preparation thereof, medicament containing them and their intermediates
WO2000032587A1 (fr) * 1998-12-01 2000-06-08 Meiji Seika Kaisha, Ltd. Substances sf2809-i, ii, iii, iv, v et vi presentant une activite d'inhibition de la chymase

Also Published As

Publication number Publication date
AU784467B2 (en) 2006-04-06
AU1053601A (en) 2001-05-14
HUP0104952A2 (en) 2002-06-29
US6921766B1 (en) 2005-07-26
DE60034545T2 (de) 2007-10-25
WO2001032214A1 (fr) 2001-05-10
CN1335778A (zh) 2002-02-13
HUP0104952A3 (en) 2006-02-28
EP1142586A4 (de) 2003-03-19
CA2358314A1 (en) 2001-05-10
KR20010100004A (ko) 2001-11-09
EP1142586B1 (de) 2007-04-25
ES2281358T3 (es) 2007-10-01
DE60034545D1 (de) 2007-06-06
EP1142586A1 (de) 2001-10-10

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties