NO332275B1 - Fast underlag for immunoanalyse, fremgangsmate for fremstilling derav, fremgangsmater for pavising av hepatitt C virus (HCV) infeksjon i en prove samt immunodiagnostisk testkit. - Google Patents
Fast underlag for immunoanalyse, fremgangsmate for fremstilling derav, fremgangsmater for pavising av hepatitt C virus (HCV) infeksjon i en prove samt immunodiagnostisk testkit. Download PDFInfo
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- NO332275B1 NO332275B1 NO20025878A NO20025878A NO332275B1 NO 332275 B1 NO332275 B1 NO 332275B1 NO 20025878 A NO20025878 A NO 20025878A NO 20025878 A NO20025878 A NO 20025878A NO 332275 B1 NO332275 B1 NO 332275B1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/18—Togaviridae; Flaviviridae
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/10—Detection of antigens from microorganism in sample from host
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21208200P | 2000-06-15 | 2000-06-15 | |
| US28086701P | 2001-04-02 | 2001-04-02 | |
| US28081101P | 2001-04-02 | 2001-04-02 | |
| PCT/US2001/019369 WO2001096875A2 (fr) | 2000-06-15 | 2001-06-14 | Dosage de combinaison antigene/anticorps du virus de l'hepatite c |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20025878D0 NO20025878D0 (no) | 2002-12-06 |
| NO20025878L NO20025878L (no) | 2003-02-12 |
| NO332275B1 true NO332275B1 (no) | 2012-08-13 |
Family
ID=27395684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20025878A NO332275B1 (no) | 2000-06-15 | 2002-12-06 | Fast underlag for immunoanalyse, fremgangsmate for fremstilling derav, fremgangsmater for pavising av hepatitt C virus (HCV) infeksjon i en prove samt immunodiagnostisk testkit. |
Country Status (23)
| Country | Link |
|---|---|
| US (5) | US6632601B2 (fr) |
| EP (2) | EP1354204B2 (fr) |
| JP (3) | JP4837229B2 (fr) |
| CN (3) | CN100463922C (fr) |
| AT (2) | ATE348337T1 (fr) |
| AU (2) | AU2001272945A1 (fr) |
| BG (1) | BG66205B1 (fr) |
| BR (2) | BRPI0111682B8 (fr) |
| CA (2) | CA2413003C (fr) |
| CY (2) | CY1107537T1 (fr) |
| CZ (1) | CZ304185B6 (fr) |
| DE (2) | DE60129598T2 (fr) |
| DK (2) | DK1354204T4 (fr) |
| ES (2) | ES2288969T3 (fr) |
| HK (2) | HK1061861A1 (fr) |
| HU (1) | HU228873B1 (fr) |
| MX (2) | MXPA02012424A (fr) |
| NO (1) | NO332275B1 (fr) |
| PL (1) | PL213363B1 (fr) |
| PT (2) | PT1354204E (fr) |
| SI (1) | SI1354204T2 (fr) |
| SK (1) | SK287694B6 (fr) |
| WO (2) | WO2001096875A2 (fr) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2162557C (fr) * | 1993-05-12 | 2004-09-28 | Amy J. Weiner | Motif conserve de la region e2/ns1 du virus de l'hepatite c |
| US7491808B2 (en) * | 2000-06-15 | 2009-02-17 | Novartis Vaccines And Diagnostics, Inc. | HCV non-structural protein mutants and uses thereof |
| MXPA02012424A (es) * | 2000-06-15 | 2003-04-25 | Chiron Corp | Ensayo de combinacion de antigenos/anticuerpos para el virus de hepatitis c. |
| US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
| AU9215101A (en) | 2000-08-17 | 2002-02-25 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| DE10106295C1 (de) * | 2001-02-02 | 2002-08-22 | Gaifar German American Inst Fo | Protein mit mehreren Antigen-Epitop-Sequenzen, welches immobilisiert ist |
| AU785380B2 (en) * | 2001-03-28 | 2007-03-15 | Ortho-Clinical Diagnostics, Inc. | A hepatitis C antigen - antibody combination assay for the early detection of HCV infection |
| CA2450710C (fr) | 2001-06-26 | 2013-11-26 | Abbott Laboratories | Procedes servant a detecter simultanement des antigenes de hcv et des anticorps anti-hcv |
| US7101683B2 (en) * | 2001-06-26 | 2006-09-05 | Abbott Laboratories | Methods for the simultaneous detection of HCV antigens and HCV antibodies |
| US7049060B2 (en) * | 2001-11-05 | 2006-05-23 | Ortho-Clinical Diagnostics, Inc. | HCV anti-core monoclonal antibodies |
| US7332269B2 (en) * | 2001-11-11 | 2008-02-19 | Ortho-Clinical Diagnostics, Inc. | HCV core protein sequences |
| FR2839555B1 (fr) | 2002-05-10 | 2007-07-27 | Bio Rad Pasteur | Procede de detection simultanee d'un antigene et d'un anticorps d'un microorganisme infectieux |
| WO2004021871A2 (fr) * | 2002-09-09 | 2004-03-18 | Chiron Corporation | Dosage biologique dans le cas du virus de l'hepatite c |
| US20040152070A1 (en) * | 2003-02-04 | 2004-08-05 | Shah Dinesh O. | Method of detection of HCV antibodies in combination assay or sole antibody assay |
| EP1668369B1 (fr) | 2003-08-20 | 2016-01-06 | ProMIS Neurosciences Inc. | Dosage de protection d'epitope et procede de detection de conformations proteiques |
| JP5070055B2 (ja) * | 2004-08-27 | 2012-11-07 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | 改変タンパク分解性切断部位を有するｈｃｖ多エピトープ融合抗原およびその使用 |
| US7658930B2 (en) * | 2005-02-02 | 2010-02-09 | Peng Cui | Kit for detecting the antibody of HCV and its preparing method |
| EP2360175B1 (fr) | 2005-11-22 | 2014-07-16 | Novartis Vaccines and Diagnostics, Inc. | Particules de type virus (vlps) de norovirus et de sapovirus |
| US7887803B2 (en) | 2005-12-02 | 2011-02-15 | Amorfix Life Sciences | Methods and compositions to treat misfolded-SOD1 mediated diseases |
| US7794692B2 (en) * | 2005-12-02 | 2010-09-14 | Amorfix Life Sciences Ltd. | Methods and compositions for detecting amyotrophic lateral sclerosis |
| DK2495327T3 (da) | 2006-03-03 | 2017-01-02 | Promis Neurosciences Inc | Fremgangsmåder og sammensætninger til at behandle og opdage sygdomme fremkaldt af fejlfoldet SOD1 |
| CN1908666B (zh) * | 2006-08-14 | 2010-05-12 | 武汉大学 | 一种检测乙肝核心抗体的双夹心法酶联免疫诊断试剂盒及应用 |
| EP2185195A2 (fr) | 2007-08-16 | 2010-05-19 | Tripep Ab | Plate-forme immunogène |
| EP2414839B1 (fr) * | 2009-03-30 | 2014-06-25 | Biomérieux | Support solide de détection du vhc |
| US20100297607A1 (en) | 2009-05-20 | 2010-11-25 | Jian Zheng | Reagents For HCV Antigen-Antibody Combination Assays |
| WO2011127316A1 (fr) | 2010-04-07 | 2011-10-13 | Novartis Ag | Procédé de génération de pseudo-particules virales de parvovirus b19 |
| BR112012031860A8 (pt) * | 2010-06-17 | 2016-09-13 | Koninklijke Philips Nv | Método para detecção de um alvo biológico em um ensaio de afinidade, disposição de detecção para um alvo biológico e porção de captura para uso em um método |
| US20130171185A1 (en) | 2010-07-06 | 2013-07-04 | Ethan Settembre | Norovirus derived immunogenic compositions and methods |
| WO2012006500A2 (fr) * | 2010-07-08 | 2012-01-12 | Abbott Laboratories | Anticorps monoclonaux contre la protéine de capside du virus de l'hépatite c |
| RU2588656C2 (ru) * | 2011-01-13 | 2016-07-10 | Орто-Клиникал Дайэгностикс, Инк. | Триплетный антиген treponema pallidum |
| FR2984328B1 (fr) | 2011-12-20 | 2016-12-30 | Bio-Rad Innovations | Procede de detection d'une infection par le virus de l'hepatite c |
| WO2014143342A1 (fr) | 2013-03-14 | 2014-09-18 | Abbott Laboratories | Antigènes recombinants ns3 de vhc et leurs mutants pour la détection d'anticorps améliorée |
| CA2906417C (fr) | 2013-03-14 | 2022-06-21 | Robert Ziemann | Anticorps monoclonaux a domaine de liaison a un lipide du coeur de vhc |
| EP2968526A4 (fr) * | 2013-03-14 | 2016-11-09 | Abbott Lab | Dosage de combinaison antigène-anticorps du virus de l'hépatite c et procédés et compositions destinés à être utilisés avec celui-ci |
| CN103630690B (zh) * | 2013-12-17 | 2014-08-20 | 朱之炜 | 丙型肝炎病毒抗原抗体联合检测试剂盒及其检测方法 |
| WO2016160046A1 (fr) | 2015-03-27 | 2016-10-06 | Ortho-Clinical Diagnostics, Inc. | Polypeptides ns4a/ns3 modifié du vhc et leurs utilisations |
| EP3285806A4 (fr) * | 2015-04-20 | 2019-03-27 | Qoolabs, Inc. | Anticorps contre le vhc à domaine unique de camélidé et leurs procédés d'utilisation |
| EP4209784A1 (fr) * | 2017-09-27 | 2023-07-12 | Bio-Rad Laboratories, Inc. | Essai de liaison par affinité numérique |
| CN110261616B (zh) * | 2019-04-30 | 2021-07-20 | 广东菲鹏生物有限公司 | 一种丙型肝炎病毒检测试剂盒 |
| CN115838420B (zh) * | 2022-10-31 | 2023-05-05 | 北京科跃中楷生物技术有限公司 | 一种可溶性hcv重组蛋白的制备方法及其制备的抗体检测试剂 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5683864A (en) * | 1987-11-18 | 1997-11-04 | Chiron Corporation | Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies |
| HU216017B (hu) * | 1987-11-18 | 1999-04-28 | Chiron Corp. | Eljárás HCV-1 polipeptidek, HCV-1 polinukleotidok, rekombináns vektorok és gazdasejtek, valamint immunesszé kit, hepatitis C vírusfertőzés elleni vakcinák, a fertőzés kimutatására szolgáló diagnosztikumok előállítására, és immunvizsgálati és vírustenyészt |
| US6171782B1 (en) | 1987-11-18 | 2001-01-09 | Chiron Corporation | Antibody compositions to HCV and uses thereof |
| US5350671A (en) | 1987-11-18 | 1994-09-27 | Chiron Corporation | HCV immunoassays employing C domain antigens |
| GB2212511B (en) * | 1987-11-18 | 1992-01-22 | Chiron Corp | Hepatitis c virus |
| JP2730153B2 (ja) | 1989-03-16 | 1998-03-25 | 日本合成ゴム株式会社 | 熱可塑性樹脂組成物およびその製造方法 |
| HU225068B1 (en) | 1989-03-17 | 2006-05-29 | Chiron Corp | Process for producing diagnostics and vaccine of nanbh |
| RO113059B1 (ro) * | 1989-05-18 | 1998-03-30 | Chiron Corp | Polinucleotida capabila de hibridizare pe o secventa hcv, metoda pentru detectarea unei secvente hcv si procedeu de eliminare a hcv din sange |
| US6194140B1 (en) * | 1990-04-04 | 2001-02-27 | Chiron Corporation | HCV NS3 protein fragments having helicase activity and improved solubility |
| HU217025B (hu) * | 1990-04-04 | 1999-11-29 | Chiron Corp. | Hepatitis C vírus-(HCV) antigénkészítmények az anti-HCV-antitestek kimutatására immunoassay-kben |
| US6312889B1 (en) | 1990-04-04 | 2001-11-06 | Chiron Corporation | Combinations of hepatitis c virus (HCV) antigens for use in immunoassays for anti-HCV antibodies |
| CA2049679C (fr) | 1990-08-24 | 2005-06-21 | Sushil G. Devare | Recherche des anticorps de l'hepatite c a l'aide d'antigenes recombinants |
| PT97247B (pt) * | 1991-04-03 | 1997-10-31 | Chiron Corp | Processo de preparacao de combinacoes de antigenios do virus da hepapite c (hcv) para uso em imunoensaios para anticorpos anti-hcv |
| RO117329B1 (ro) | 1991-06-24 | 2002-01-30 | Chiron Corp Emeryville | Polipeptide care contin o secventa a virusului hepatitei c |
| UA39944C2 (uk) | 1992-07-07 | 2001-07-16 | Чірон Корпорейшн | Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі |
| CA2139100C (fr) * | 1993-04-27 | 2009-06-23 | Geert Maertens | Nouvelles sequences genotypiques du virus de l'hepatite c et leur emploi a titre d'agents diagnostiques et therapeutiques |
| US6001604A (en) * | 1993-12-29 | 1999-12-14 | Bio-Technology General Corp. | Refolding of proinsulins without addition of reducing agents |
| JP3217600B2 (ja) | 1994-07-12 | 2001-10-09 | 株式会社先端生命科学研究所 | 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ |
| DE4428705A1 (de) * | 1994-08-12 | 1996-02-15 | Boehringer Mannheim Gmbh | Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus |
| US5843752A (en) | 1995-05-12 | 1998-12-01 | Schering Corporation | Soluble active hepatitis C virus protease |
| US5990276A (en) | 1996-05-10 | 1999-11-23 | Schering Corporation | Synthetic inhibitors of hepatitis C virus NS3 protease |
| US6514731B1 (en) * | 1996-05-24 | 2003-02-04 | Chiron Corporation | Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens |
| ATE311463T1 (de) | 1996-05-24 | 2005-12-15 | Chiron Corp | Fusionsprotein mit multiplen epitopen |
| US6322965B1 (en) * | 1997-02-10 | 2001-11-27 | Advanced Life Science Institute, Inc. | Chimera antigen peptide |
| CA2303123C (fr) * | 1997-09-22 | 2006-04-11 | Chiron Corporation | Procede pour detecter des anticorps dans un echantillon |
| JP3514729B2 (ja) * | 1998-07-30 | 2004-03-31 | 株式会社先端生命科学研究所 | Ｃ型肝炎ウイルスの測定方法 |
| MXPA02012424A (es) * | 2000-06-15 | 2003-04-25 | Chiron Corp | Ensayo de combinacion de antigenos/anticuerpos para el virus de hepatitis c. |
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2001
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- 2001-06-14 AT AT01952160T patent/ATE348337T1/de active
- 2001-06-14 SK SK1777-2002A patent/SK287694B6/sk not_active IP Right Cessation
- 2001-06-14 CZ CZ20024058A patent/CZ304185B6/cs not_active IP Right Cessation
- 2001-06-14 DE DE60129598T patent/DE60129598T2/de not_active Expired - Lifetime
- 2001-06-14 JP JP2002510948A patent/JP4837229B2/ja not_active Expired - Lifetime
- 2001-06-14 ES ES01952156T patent/ES2288969T3/es not_active Expired - Lifetime
- 2001-06-14 DK DK01952160.8T patent/DK1354204T4/da active
- 2001-06-14 PT PT01952160T patent/PT1354204E/pt unknown
- 2001-06-14 BR BRPI0111682A patent/BRPI0111682B8/pt not_active IP Right Cessation
- 2001-06-14 CA CA2413003A patent/CA2413003C/fr not_active Expired - Lifetime
- 2001-06-14 EP EP01952160A patent/EP1354204B2/fr not_active Expired - Lifetime
- 2001-06-14 CN CNB2004100116606A patent/CN100463922C/zh not_active Expired - Lifetime
- 2001-06-14 EP EP01952156A patent/EP1350105B1/fr not_active Expired - Lifetime
- 2001-06-14 PT PT01952156T patent/PT1350105E/pt unknown
- 2001-06-14 DE DE60125240T patent/DE60125240T3/de not_active Expired - Lifetime
- 2001-06-14 AU AU2001272945A patent/AU2001272945A1/en not_active Abandoned
- 2001-06-14 DK DK01952156T patent/DK1350105T3/da active
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- 2001-06-14 CN CNB018112463A patent/CN1214244C/zh not_active Expired - Lifetime
- 2001-06-14 WO PCT/US2001/019369 patent/WO2001096875A2/fr active IP Right Grant
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- 2001-06-14 PL PL365599A patent/PL213363B1/pl not_active IP Right Cessation
- 2001-06-14 HU HU0500444A patent/HU228873B1/hu unknown
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- 2001-06-14 MX MXPA02012401A patent/MXPA02012401A/es active IP Right Grant
- 2001-06-14 AT AT01952156T patent/ATE368221T1/de active
- 2001-06-14 SI SI200130682T patent/SI1354204T2/sl unknown
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- 2001-06-14 WO PCT/US2001/019156 patent/WO2001096870A2/fr active IP Right Grant
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- 2001-06-14 JP JP2002510953A patent/JP4834279B2/ja not_active Expired - Lifetime
- 2001-06-14 CA CA2412035A patent/CA2412035C/fr not_active Expired - Lifetime
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2002
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2003
- 2003-01-07 BG BG107441A patent/BG66205B1/bg unknown
- 2003-08-08 US US10/637,323 patent/US6797809B2/en not_active Expired - Lifetime
- 2003-08-19 US US10/643,853 patent/US7319144B2/en not_active Expired - Lifetime
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2004
- 2004-07-06 HK HK04104878A patent/HK1061861A1/xx not_active IP Right Cessation
- 2004-07-26 US US10/899,715 patent/US7241879B2/en not_active Expired - Lifetime
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2005
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2007
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2011
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