CA2303123C - Procede pour detecter des anticorps dans un echantillon - Google Patents

Procede pour detecter des anticorps dans un echantillon Download PDF

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Publication number
CA2303123C
CA2303123C CA002303123A CA2303123A CA2303123C CA 2303123 C CA2303123 C CA 2303123C CA 002303123 A CA002303123 A CA 002303123A CA 2303123 A CA2303123 A CA 2303123A CA 2303123 C CA2303123 C CA 2303123C
Authority
CA
Canada
Prior art keywords
ligand
target antigen
antibodies
coupled
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002303123A
Other languages
English (en)
Other versions
CA2303123A1 (fr
Inventor
David Y. Chien
Phillip Arcangel
Stephen Tirell
Wanda Zeigler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Grifols Worldwide Operations Ltd
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of CA2303123A1 publication Critical patent/CA2303123A1/fr
Application granted granted Critical
Publication of CA2303123C publication Critical patent/CA2303123C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/82—Hepatitis associated antigens and antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CA002303123A 1997-09-22 1998-09-22 Procede pour detecter des anticorps dans un echantillon Expired - Lifetime CA2303123C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5970397P 1997-09-22 1997-09-22
US60/059,703 1997-09-22
US8392198P 1998-05-01 1998-05-01
US60/083,921 1998-05-01
PCT/US1998/019693 WO1999015898A1 (fr) 1997-09-22 1998-09-22 Procede pour detecter des anticorps dans un echantillon

Publications (2)

Publication Number Publication Date
CA2303123A1 CA2303123A1 (fr) 1999-04-01
CA2303123C true CA2303123C (fr) 2006-04-11

Family

ID=26739077

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002303123A Expired - Lifetime CA2303123C (fr) 1997-09-22 1998-09-22 Procede pour detecter des anticorps dans un echantillon

Country Status (12)

Country Link
US (1) US6391540B1 (fr)
EP (1) EP1021719B1 (fr)
JP (1) JP4124961B2 (fr)
AT (1) ATE354800T1 (fr)
AU (1) AU9497998A (fr)
CA (1) CA2303123C (fr)
CY (1) CY1107621T1 (fr)
DE (1) DE69837155T2 (fr)
DK (1) DK1021719T3 (fr)
ES (1) ES2281934T3 (fr)
PT (1) PT1021719E (fr)
WO (1) WO1999015898A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6815160B1 (en) 1999-07-28 2004-11-09 Chiron Corporation Hepatitis C viral antigen immunoassay detection systems
JP5498637B2 (ja) * 1999-07-28 2014-05-21 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド Ｃ型肝炎ウイルス抗原免疫アッセイ検出システム
US6995299B2 (en) * 1999-11-02 2006-02-07 University Of Connecticut Propagation of human hepatocytes in non-human animals
DE10006432A1 (de) * 2000-02-14 2001-08-16 Ganzimmun Inst Fuer Ganzheitli Verfahren zum Nachweis von Helicobacter pylori in Stuhl- und Speichelproben
AU2001272945A1 (en) * 2000-06-15 2001-12-24 Chiron Corporation Immunoassays for anti-hcv antibodies
GB0325483D0 (en) * 2003-10-31 2003-12-03 Plasmacute As Assay
MXPA06011738A (es) * 2004-04-15 2007-01-25 Allied Biotech Inc Metodos y aparato para la deteccion de infeccion viral.
CN103777024B (zh) 2007-05-08 2017-04-12 霍夫曼-拉罗奇有限公司 用于检测特异性免疫球蛋白g类抗体的方法
CN105486856A (zh) * 2015-12-24 2016-04-13 泰州泽成生物技术有限公司 一种定性检测丙型肝炎抗体的试剂盒及其制备方法和应用
CN107167584B (zh) * 2017-05-27 2020-03-03 北京热景生物技术股份有限公司 化学发光免疫分析仪
EP3853612A4 (fr) 2018-09-18 2021-10-27 Siemens Healthcare Diagnostics, Inc. Méthodes et réactifs de dosages immunologiques du virus zika

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2556840B1 (fr) 1983-12-16 1987-12-24 Immunotech Sa Procede de dosage in vitro des immunoglobulines specifiques d'un ou plusieurs allergenes et reactifs et moyens pour la mise en oeuvre de ce procede
US4737453A (en) * 1984-12-12 1988-04-12 Immunomedics, Inc. Sandwich immunoassay utilizing a separation specific binding substance
ES2059601T3 (es) 1988-05-11 1994-11-16 Abbott Lab Un inmunoensayo para la deteccion de anti-hbc en una muestra biologica.
US5656426A (en) 1988-08-01 1997-08-12 Chiron Diagnostics Corporation Functionaized hydrophilic acridinium esters
JP2733138B2 (ja) * 1990-04-04 1998-03-30 カイロン コーポレイション 抗ｈｃｖ抗体の免疫アッセイに使用するｃ型肝炎ウイルス（ｈｃｖ）抗原の組合せ
EP0473065A3 (en) * 1990-08-29 1992-08-26 Abbott Laboratories Simultaneous assay for detecting two or more analytes
KR930702680A (ko) * 1990-11-09 1993-09-09 찰스 엠.브룩 증폭된 불균질 화학발광 면역 검정법
JPH04310861A (ja) * 1991-04-09 1992-11-02 Kazuo Yanagi 抗ｅｂｎａ抗体の測定方法および抗ｅｂｎａ抗体測定キット
CA2104596A1 (fr) * 1992-01-06 1993-07-07 Dade International Inc. Reactif immunochimique multi-test et methode d'utilisation
JPH06213895A (ja) * 1992-10-16 1994-08-05 Evernew Biotec Inc Ｃ型肝炎の急性期の決定方法
US5395752A (en) 1993-03-19 1995-03-07 Ciba Corning Diagnostics Corp. Long emission wavelength chemiluminescent compounds and their use in test assays
JPH07508102A (ja) 1993-04-14 1995-09-07 ミュレクス　ダイアノスティクス　コーポレイション アッセイ
KR100312534B1 (ko) 1993-04-28 2002-05-13 성재갑 씨(c)형간염및비(b)형간염동시측정면역블롯검정키트및면역블롯검정법
EP0698101B1 (fr) * 1993-05-05 2004-11-03 Common Services Agency Virus de l'hepatite c de type 4, 5 et 6
WO1994026932A1 (fr) 1993-05-13 1994-11-24 United States Of America, As Represented By The Secretary, Department Of Health And Human Services Dosage immonologique marque a l'acide nucleique
DE19502386A1 (de) 1995-01-26 1996-08-01 Boehringer Mannheim Gmbh Stabilisierung von Peptiden und Polypeptiden in immunologischen Tests durch Zusatz von kleinen Hitzeschockproteinen
US5705330A (en) 1995-04-14 1998-01-06 Abbott Laboratories Chemiluminescent immunoassay for antibody detection
US5616460A (en) 1995-06-07 1997-04-01 Abbott Laboratories Buffer composition for reagents for immunoassay
AU719929B2 (en) 1996-05-24 2000-05-18 Grifols Worldwide Operations Limited Multiple epitope fusion protein

Also Published As

Publication number Publication date
ES2281934T3 (es) 2007-10-01
CY1107621T1 (el) 2013-03-13
WO1999015898A1 (fr) 1999-04-01
DE69837155T2 (de) 2007-06-21
DK1021719T3 (da) 2007-06-18
DE69837155D1 (de) 2007-04-05
US6391540B1 (en) 2002-05-21
EP1021719B1 (fr) 2007-02-21
JP4124961B2 (ja) 2008-07-23
AU9497998A (en) 1999-04-12
JP2001517797A (ja) 2001-10-09
CA2303123A1 (fr) 1999-04-01
PT1021719E (pt) 2007-03-30
EP1021719A1 (fr) 2000-07-26
ATE354800T1 (de) 2007-03-15

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Effective date: 20180924