NO20076056L - Fremgangsmater for rensing av FC region inneholdende proteiner - Google Patents

Fremgangsmater for rensing av FC region inneholdende proteiner

Info

Publication number
NO20076056L
NO20076056L NO20076056A NO20076056A NO20076056L NO 20076056 L NO20076056 L NO 20076056L NO 20076056 A NO20076056 A NO 20076056A NO 20076056 A NO20076056 A NO 20076056A NO 20076056 L NO20076056 L NO 20076056L
Authority
NO
Norway
Prior art keywords
methods
polypeptides
purifying
protein
present application
Prior art date
Application number
NO20076056A
Other languages
English (en)
Inventor
Ranganathan Godavarti
Timothy Iskra
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20076056L publication Critical patent/NO20076056L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SAMMENDRAG Foreliggende søknad tilveiebringer metoder for rensing av polypeptider som har en Fc-region, for eksempel antistoffer eller antistoff-fusjoner, ved adsorbering av polypeptidene til et Fc-bindende middel, så som for eksempel Protein A eller Protein G, fulgt av vask med en divalent kationsalt-buffer for å fjerne urenheter og påfølgende gjenvinning av de adsorberte polypeptider. Foreliggende søknad angår også metoder for eluering av det rensede polypeptid så vel som innføring av metodene i en renseserie. Sett omfattende komponenter for å utføre metodene og instruksjoner for anvendelse er også gitt.
NO20076056A 2005-06-17 2007-11-26 Fremgangsmater for rensing av FC region inneholdende proteiner NO20076056L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69182105P 2005-06-17 2005-06-17
PCT/US2006/023478 WO2006138553A2 (en) 2005-06-17 2006-06-16 Methods of purifying fc region containing proteins

Publications (1)

Publication Number Publication Date
NO20076056L true NO20076056L (no) 2008-01-11

Family

ID=37433887

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20076082A NO20076082L (no) 2005-06-17 2007-11-26 Fremgangsmater for rensing av anti A beta antistoffer
NO20076056A NO20076056L (no) 2005-06-17 2007-11-26 Fremgangsmater for rensing av FC region inneholdende proteiner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20076082A NO20076082L (no) 2005-06-17 2007-11-26 Fremgangsmater for rensing av anti A beta antistoffer

Country Status (26)

Country Link
US (3) US7825223B2 (no)
EP (3) EP1896504B1 (no)
JP (2) JP5150488B2 (no)
KR (2) KR101247836B1 (no)
CN (3) CN101365722A (no)
AR (2) AR053632A1 (no)
AU (2) AU2006261185B2 (no)
BR (2) BRPI0611599A2 (no)
CA (2) CA2611816C (no)
CR (2) CR9576A (no)
EA (2) EA015148B1 (no)
EC (1) ECSP088086A (no)
ES (2) ES2402650T3 (no)
HK (1) HK1117174A1 (no)
IL (2) IL187642A (no)
MA (1) MA29609B1 (no)
MX (2) MX2007015952A (no)
MY (1) MY144484A (no)
NI (1) NI200700329A (no)
NO (2) NO20076082L (no)
NZ (1) NZ565044A (no)
RU (1) RU2415865C2 (no)
SG (1) SG162806A1 (no)
TW (2) TW200740839A (no)
WO (2) WO2006138737A2 (no)
ZA (2) ZA200710330B (no)

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