NO20084672L - Binder for C-reaktiv protein - Google Patents
Binder for C-reaktiv proteinInfo
- Publication number
- NO20084672L NO20084672L NO20084672A NO20084672A NO20084672L NO 20084672 L NO20084672 L NO 20084672L NO 20084672 A NO20084672 A NO 20084672A NO 20084672 A NO20084672 A NO 20084672A NO 20084672 L NO20084672 L NO 20084672L
- Authority
- NO
- Norway
- Prior art keywords
- crp
- polypeptide
- reactive protein
- binds
- relates
- Prior art date
Links
- 108010074051 C-Reactive Protein Proteins 0.000 title abstract 6
- 102100032752 C-reactive protein Human genes 0.000 title abstract 6
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- YHHSONZFOIEMCP-UHFFFAOYSA-N 2-(trimethylazaniumyl)ethyl hydrogen phosphate Chemical class C[N+](C)(C)CCOP(O)([O-])=O YHHSONZFOIEMCP-UHFFFAOYSA-N 0.000 abstract 1
- 102000002067 Protein Subunits Human genes 0.000 abstract 1
- 108010001267 Protein Subunits Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000000539 dimer Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
- A61K47/544—Phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4737—C-reactive protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4737—C-reactive protein
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
Abstract
Oppfinnelsen angår en polypeptiddimer, hvori begge protomerer har en sekvens ifølge SEQ ID NO: 1, hvori minst ett fosfocholinderivat er festet til nevnte polypeptid. Nevnte polypeptid viser en spesifikk binding for C-reaktivt protein (CRP). Oppfinnelsen angår videre anvendelsen av polypeptidet i undersøkelser for å bestemme konsentrasjonen av CRP, rensing av CRP og sammensetningen omfattende CRP.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0600794 | 2006-04-07 | ||
PCT/SE2007/050227 WO2007117215A1 (en) | 2006-04-07 | 2007-04-10 | Binder for c-reactive protein |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20084672L true NO20084672L (no) | 2008-12-10 |
Family
ID=38581404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20084672A NO20084672L (no) | 2006-04-07 | 2008-11-07 | Binder for C-reaktiv protein |
Country Status (7)
Country | Link |
---|---|
US (2) | US8017347B2 (no) |
EP (1) | EP2007801A4 (no) |
JP (1) | JP5232769B2 (no) |
CN (1) | CN101415727A (no) |
CA (1) | CA2647271A1 (no) |
NO (1) | NO20084672L (no) |
WO (1) | WO2007117215A1 (no) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105063001A (zh) | 2009-09-16 | 2015-11-18 | 新基阿维罗米克斯研究公司 | 蛋白激酶复合物和含有该复合物的药物组合物以及它们的用途 |
KR101118760B1 (ko) * | 2009-12-29 | 2012-03-13 | 재단법인대구경북과학기술원 | 펜트락신 단백질 검출용 분자각인 고분자 및 그 제조방법 |
KR20130067487A (ko) | 2009-12-30 | 2013-06-25 | 아빌라 테라퓨틱스, 인크. | 단백질의 리간드-지정 공유 변형 |
EP2571487B1 (en) * | 2010-05-21 | 2023-01-04 | Siemens Healthcare Diagnostics Inc. | Zwitterionic reagents |
CN103313724A (zh) * | 2010-09-06 | 2013-09-18 | 莫徳普罗有限公司 | 化合物和方法 |
EP2957563A1 (en) * | 2014-06-19 | 2015-12-23 | Pentracor GmbH | Separation material comprising phosphoryl choline derivatives |
EP3020726A1 (de) * | 2014-11-12 | 2016-05-18 | Pentracor GmbH | Verwendung einer Citrat-Lösung zur affinitätschromatographischen Aufreinigung von CRP mittels Phosphocholin und dessen Derivaten |
CN109946273A (zh) * | 2019-03-13 | 2019-06-28 | 长春理工大学 | 一种用于检测c-反应蛋白的荧光探针及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH095325A (ja) * | 1995-06-19 | 1997-01-10 | Nissui Pharm Co Ltd | 免疫凝集反応試薬および免疫分析方法 |
JP4242499B2 (ja) * | 1999-03-03 | 2009-03-25 | オリエンタル酵母工業株式会社 | ホスホリルコリンを用いたcrpの測定方法 |
US7390795B2 (en) | 2000-12-18 | 2008-06-24 | Pentraxin Therapeutics Limited | Treatment and prevention of tissue damage |
SE0202473D0 (sv) * | 2001-11-21 | 2002-08-19 | A & Science Ab | Site selective acylation |
SE0200968D0 (sv) * | 2002-03-26 | 2002-03-26 | Lars Baltzer | Novel polypeptide scaffolds and use thereof |
DE10228103A1 (de) | 2002-06-24 | 2004-01-15 | Bayer Cropscience Ag | Fungizide Wirkstoffkombinationen |
EP1597281A1 (en) | 2003-02-27 | 2005-11-23 | TheraVision GmbH | Method for reducing levels of c-reactive protein |
-
2007
- 2007-04-10 EP EP07748388A patent/EP2007801A4/en not_active Withdrawn
- 2007-04-10 CN CNA2007800126012A patent/CN101415727A/zh active Pending
- 2007-04-10 US US12/225,386 patent/US8017347B2/en not_active Expired - Fee Related
- 2007-04-10 WO PCT/SE2007/050227 patent/WO2007117215A1/en active Application Filing
- 2007-04-10 CA CA002647271A patent/CA2647271A1/en not_active Abandoned
- 2007-04-10 JP JP2009504167A patent/JP5232769B2/ja not_active Expired - Fee Related
-
2008
- 2008-11-07 NO NO20084672A patent/NO20084672L/no not_active Application Discontinuation
-
2011
- 2011-08-26 US US13/218,875 patent/US8436138B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN101415727A (zh) | 2009-04-22 |
US8436138B2 (en) | 2013-05-07 |
US20120053124A1 (en) | 2012-03-01 |
WO2007117215A1 (en) | 2007-10-18 |
US8017347B2 (en) | 2011-09-13 |
US20090305298A1 (en) | 2009-12-10 |
EP2007801A4 (en) | 2010-08-04 |
EP2007801A1 (en) | 2008-12-31 |
JP5232769B2 (ja) | 2013-07-10 |
WO2007117215A8 (en) | 2009-11-05 |
JP2009533339A (ja) | 2009-09-17 |
CA2647271A1 (en) | 2007-10-18 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |