NO20052626L - Middel for forhindring eller behandling av neuropati - Google Patents
Middel for forhindring eller behandling av neuropatiInfo
- Publication number
- NO20052626L NO20052626L NO20052626A NO20052626A NO20052626L NO 20052626 L NO20052626 L NO 20052626L NO 20052626 A NO20052626 A NO 20052626A NO 20052626 A NO20052626 A NO 20052626A NO 20052626 L NO20052626 L NO 20052626L
- Authority
- NO
- Norway
- Prior art keywords
- optionally substituted
- group
- hydrocarbon group
- ring
- neuropathy
- Prior art date
Links
Classifications
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- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/402—1-aryl substituted, e.g. piretanide
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- C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
Abstract
Foreliggende oppfinnelse angår et middel for å hindre eller behandle neuropati som har overlegen virkning og lav toksisitet. Dette middelet innbefatter en forbindelse representert ved formelen, hvori ring A er et 5-leddet heterosykel som inneholder to eller flere nitrogenatomer, som ytterligere kan ha substituenter; B er en eventuelt substituert hydrokarbongruppe eller en eventuelt substituert heterosyklisk gruppe; X er en divalent asyklisk hydrokarbongruppe; Z er -0-, -S-, -NR2-, -CONR2- eller -NR2CO- (R2 er et hydrogenatom og en eventuelt substituert alkylgruppe); Y er en binding eller en divalent asyklisk hydrokarbongruppe; R1 er en eventuelt substituert syklisk gruppe, en eventuelt substituert aminogruppe eller en eventuelt substituert acylgruppe, forutsatt at når det 5-leddede aromatiske heterosykelet representert ved ring A er imidazol, da kan Z ikke være -O-, eller et salt derav.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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JP2002320153 | 2002-11-01 | ||
PCT/JP2003/013901 WO2004039365A1 (en) | 2002-11-01 | 2003-10-30 | Agent for preventing or treating neuropathy |
Publications (2)
Publication Number | Publication Date |
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NO20052626D0 NO20052626D0 (no) | 2005-05-31 |
NO20052626L true NO20052626L (no) | 2005-07-01 |
Family
ID=32211840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20052626A NO20052626L (no) | 2002-11-01 | 2005-05-31 | Middel for forhindring eller behandling av neuropati |
Country Status (20)
Country | Link |
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US (2) | US7423159B2 (no) |
EP (1) | EP1556032A1 (no) |
JP (1) | JP2008231115A (no) |
KR (1) | KR20050062645A (no) |
CN (1) | CN1731994A (no) |
AR (1) | AR041867A1 (no) |
AU (1) | AU2003278600A1 (no) |
BR (1) | BR0315815A (no) |
CA (1) | CA2504511A1 (no) |
CO (1) | CO5570666A2 (no) |
CR (2) | CR7849A (no) |
MX (1) | MXPA05004505A (no) |
NO (1) | NO20052626L (no) |
NZ (1) | NZ540381A (no) |
PE (1) | PE20040609A1 (no) |
PL (1) | PL376733A1 (no) |
RU (1) | RU2337682C2 (no) |
TW (1) | TW200416029A (no) |
WO (1) | WO2004039365A1 (no) |
ZA (1) | ZA200503967B (no) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7339052B2 (en) * | 2005-02-08 | 2008-03-04 | Honeywell International Inc. | Phosphoramidite activator for oligonucleotide synthesis |
EP1754476A1 (en) * | 2005-08-18 | 2007-02-21 | Schwarz Pharma Ag | Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia |
US20070043120A1 (en) * | 2005-08-18 | 2007-02-22 | Bettina Beyreuther | Therapeutic combination for painful medical conditions |
MX2008016000A (es) | 2006-06-15 | 2009-03-05 | Sanol Arznei Schwarz Gmbh | Composicion farmaceutica con efecto anticonvulsivante sinergistico. |
JPWO2008010511A1 (ja) | 2006-07-19 | 2009-12-17 | 武田薬品工業株式会社 | スクリーニング方法 |
EP1939180A1 (en) | 2006-12-20 | 2008-07-02 | sanofi-aventis | Heteroarylacrylamides and their use as pharmaceuticals for the stimulation of the expression of endothelial NO synthase |
SG176464A1 (en) * | 2008-05-09 | 2011-12-29 | Agency Science Tech & Res | Diagnosis and treatment of kawasaki disease |
TW201014850A (en) | 2008-09-25 | 2010-04-16 | Takeda Pharmaceutical | Solid pharmaceutical composition |
JP5535931B2 (ja) | 2008-10-27 | 2014-07-02 | 武田薬品工業株式会社 | 二環性化合物 |
US8557805B2 (en) | 2008-12-29 | 2013-10-15 | Takeda Pharmaceutical Company Limited | Fused ring compound and use thereof |
FR2943246B1 (fr) * | 2009-03-19 | 2011-07-29 | Biocodex | Compose pour son utilisation dans le traitement des neuropathies peripheriques |
EP2440541A1 (en) | 2009-06-09 | 2012-04-18 | Takeda Pharmaceutical Company Limited | Novel fused cyclic compound and use thereof |
IN2012DN00954A (no) | 2009-07-28 | 2015-04-10 | Takeda Pharmaceutical | |
KR101149821B1 (ko) | 2010-04-05 | 2012-05-24 | 하나제약 주식회사 | 디페닐아세테이트 유도체의 새로운 제조방법 |
JP5693611B2 (ja) | 2010-04-27 | 2015-04-01 | 武田薬品工業株式会社 | 二環性化合物 |
GEP20146195B (en) | 2010-06-16 | 2014-11-10 | Takeda Pharmaceuticals Co | Crystal of amide compound |
EP2617726A4 (en) | 2010-09-17 | 2014-05-14 | Takeda Pharmaceutical | DIABETES THERAPEUTIC |
US8729102B2 (en) | 2010-11-30 | 2014-05-20 | Takeda Pharmaceutical Company Limited | Bicyclic compound |
RU2445066C1 (ru) * | 2011-01-13 | 2012-03-20 | Государственное образовательное учреждение высшего профессионального образования "Астраханская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО АГМА Росздрава) | Способ лечения невропатии лицевого нерва |
KR20140015371A (ko) | 2011-02-17 | 2014-02-06 | 다케다 야쿠힌 고교 가부시키가이샤 | 광학적 활성 디히드로벤조푸란 유도체 제조 방법 |
EA201490406A1 (ru) * | 2011-07-29 | 2014-07-30 | Кариофарм Терапевтикс, Инк. | Модуляторы ядерного транспорта и их применение |
PL3333164T3 (pl) | 2011-07-29 | 2023-12-18 | Karyopharm Therapeutics Inc. | Modulatory transportu jądrowego zawierające ugrupowanie hydrazydu i ich zastosowania |
CA2853221A1 (en) | 2011-10-24 | 2013-05-02 | Tohru Yamashita | Bicyclic compound |
RU2486918C1 (ru) * | 2011-10-25 | 2013-07-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Способ стимулирования восстановления периферической иннервации тканей с помощью векторных конструкций |
WO2013105676A1 (en) | 2012-01-12 | 2013-07-18 | Takeda Pharmaceutical Company Limited | Benzimidazole derivatives as mch receptor antagonists |
WO2013122029A1 (ja) | 2012-02-13 | 2013-08-22 | 武田薬品工業株式会社 | 芳香環化合物 |
WO2013122028A1 (ja) | 2012-02-13 | 2013-08-22 | 武田薬品工業株式会社 | 芳香環化合物 |
WO2013122260A1 (en) | 2012-02-15 | 2013-08-22 | Takeda Pharmaceutical Company Limited | Tablet |
JP6106179B2 (ja) | 2012-02-24 | 2017-03-29 | 武田薬品工業株式会社 | 芳香環化合物 |
WO2013147026A1 (ja) | 2012-03-29 | 2013-10-03 | 武田薬品工業株式会社 | 芳香環化合物 |
EP3404027B1 (en) | 2012-05-09 | 2020-03-04 | Biogen MA Inc. | Nuclear transport modulators and uses thereof |
WO2013168759A1 (ja) | 2012-05-10 | 2013-11-14 | 武田薬品工業株式会社 | 芳香環化合物 |
WO2013168760A1 (ja) | 2012-05-10 | 2013-11-14 | 武田薬品工業株式会社 | 芳香環化合物 |
CA2874820C (en) | 2012-06-05 | 2020-06-09 | Takeda Pharmaceutical Company Limited | Disintegrable and preservation stable solid preparation |
JP2015127299A (ja) | 2012-07-19 | 2015-07-09 | 武田薬品工業株式会社 | 固形製剤 |
JP6247697B2 (ja) | 2013-03-14 | 2017-12-13 | 武田薬品工業株式会社 | スピロアゼチジンイソキサゾール誘導体及びそのsstr5アンタゴニストとしての使用 |
WO2014144772A1 (en) | 2013-03-15 | 2014-09-18 | Karyopharm Therapeutics Inc. | Methods of promoting wound healing using crm1 inhibitors |
US10005720B2 (en) | 2013-04-05 | 2018-06-26 | North Carolina Central University | Compounds useful for the treatment of metabolic disorders and synthesis of the same |
RU2538621C2 (ru) * | 2013-05-08 | 2015-01-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Способ стимулирования восстановления иннервации тканей после травм и ишемии с помощью векторной конструкции |
CN110183422B (zh) | 2013-06-21 | 2023-07-14 | 卡尔约药物治疗公司 | 核转运调节剂及其用途 |
WO2015005489A1 (en) | 2013-07-09 | 2015-01-15 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
WO2015020184A1 (ja) | 2013-08-09 | 2015-02-12 | 武田薬品工業株式会社 | 芳香環化合物 |
JO3442B1 (ar) | 2013-10-07 | 2019-10-20 | Takeda Pharmaceuticals Co | مضادات ذات نوع فرعي من مستقبل سوماتوستاتين 5 (sstr5) |
ITMI20132201A1 (it) | 2013-12-23 | 2015-06-24 | Isagro Spa | Processo per la sintesi regioselettiva di pirazoli |
US9346776B2 (en) | 2014-02-13 | 2016-05-24 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
US9428470B2 (en) | 2014-02-13 | 2016-08-30 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
WO2015155713A1 (en) | 2014-04-09 | 2015-10-15 | Isagro S.P.A. | Process for the regioselective synthesis of 1,3, 4 -substituted pyrazoles |
DK3180331T3 (da) | 2014-08-15 | 2022-09-12 | Karyopharm Therapeutics Inc | Polymorfer af selinexor |
MA43529A (fr) | 2015-12-31 | 2018-11-07 | Karyopharm Therapeutics Inc | Modulateurs de transport nucléaire et leurs utilisations |
US10709706B2 (en) | 2015-12-31 | 2020-07-14 | Karopharm Therapeutics Inc. | Nuclear transport modulators and uses thereof |
WO2018098472A1 (en) | 2016-11-28 | 2018-05-31 | Karyopharm Therapeutics Inc. | Crm1 inhibitors for treating epilepsy |
JOP20180029A1 (ar) | 2017-03-30 | 2019-01-30 | Takeda Pharmaceuticals Co | مركب حلقي غير متجانس |
JOP20180028A1 (ar) | 2017-03-31 | 2019-01-30 | Takeda Pharmaceuticals Co | مركب ببتيد |
AR111199A1 (es) | 2017-03-31 | 2019-06-12 | Takeda Pharmaceuticals Co | Compuesto aromático agonista de gpr40 |
CA3058578A1 (en) | 2017-03-31 | 2018-10-04 | Takeda Pharmaceutical Company Limited | Aromatic compound |
MX2020009950A (es) | 2018-03-23 | 2021-04-28 | Carmot Therapeutics Inc | Moduladores de receptores acoplados a proteina g. |
WO2020045326A1 (ja) | 2018-08-27 | 2020-03-05 | 株式会社スコヒアファーマ | 安息香酸エステル化合物 |
US20220135638A1 (en) | 2018-09-24 | 2022-05-05 | Takeda Pharmaceutical Company Limited | Gip receptor agonist peptide compounds and uses thereof |
JP2022500483A (ja) | 2018-09-24 | 2022-01-04 | 武田薬品工業株式会社 | Gip受容体アゴニストペプチド化合物及びその使用 |
GB201901559D0 (en) * | 2019-02-05 | 2019-03-27 | Syngenta Crop Protection Ag | Herbicidal compositions |
MX2022011816A (es) | 2020-03-25 | 2022-10-10 | Takeda Pharmaceuticals Co | Dosificacion qd de compuestos peptidicos agonistas del receptor de gip y sus usos. |
KR20220157409A (ko) | 2020-03-25 | 2022-11-29 | 다케다 야쿠힌 고교 가부시키가이샤 | Gip 수용체 작용제 펩티드 화합물 및 이의 용도 |
BR112023023559A2 (pt) | 2021-05-13 | 2024-02-06 | Carmot Therapeutics Inc | Moduladores de receptores acoplados à proteína g |
WO2023169456A1 (en) | 2022-03-09 | 2023-09-14 | Gasherbrum Bio , Inc. | Heterocyclic glp-1 agonists |
WO2023179542A1 (en) | 2022-03-21 | 2023-09-28 | Gasherbrum Bio , Inc. | 5,8-dihydro-1,7-naphthyridine derivatives as glp-1 agonists for the treatment of diabetes |
WO2023198140A1 (en) | 2022-04-14 | 2023-10-19 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3702330A (en) * | 1970-10-05 | 1972-11-07 | Merck & Co Inc | Imidazolyl acrylic acid derivatives |
US4172136A (en) | 1975-12-23 | 1979-10-23 | Boehringer Mannheim Gmbh | 3-Nitropyrazole compounds and anti-microbial compositions |
DE2739689C2 (de) * | 1977-09-02 | 1986-10-16 | Euratom | Thermische Wärmepumpe |
DE2853854A1 (de) * | 1978-12-13 | 1980-07-03 | Patra Patent Treuhand | Leuchtstofflampen-set |
DE3002413A1 (de) * | 1980-01-24 | 1981-07-30 | Hoechst Ag, 6000 Frankfurt | N,n-dialkyl-o-(pyrazol-5-yl)-carbaminsaeureester, verfahren zu ihrer herstellung und ihre verwendung als insektizide |
JPH064584B2 (ja) | 1984-02-29 | 1994-01-19 | 沢井製薬株式会社 | 新規アニリド誘導体 |
KR890001651B1 (ko) | 1984-06-22 | 1989-05-12 | 산도즈 파마슈티칼스 코포레이션 | 메발로노락톤의 피라졸 동족체 및 이의 유도체의 제조방법 |
US4835280A (en) * | 1985-01-18 | 1989-05-30 | Boehringer Mannheim Gmbh | Indoline compounds for synthesis of pharmaceutically active pyrrolobenzimidazoles |
US5464860A (en) * | 1988-11-30 | 1995-11-07 | Novapharme | N(pyrazol-3-yl) benzamides and pharmaceutical compositions |
JPH04184435A (ja) | 1990-11-20 | 1992-07-01 | Fuji Photo Film Co Ltd | ハロゲン化銀カラー写真感光材料及びその処理方法 |
US5172136A (en) * | 1991-09-06 | 1992-12-15 | Eastman Kodak Company | Color registration is scanning thermal printer |
US5250504A (en) * | 1991-11-20 | 1993-10-05 | Fmc Corporation | Herbicidal β-pyrazolylacrylic acids |
US5541213A (en) | 1993-06-24 | 1996-07-30 | Eisai Co., Ltd. | Propenoic acid derivatives diazole propenoic acid compounds which have useful pharmaceutical utility |
US5552420A (en) * | 1994-05-13 | 1996-09-03 | Sterling Winthrop Inc. | Therapeutic phenoxyalkylazoles and phenoxyalkylazines |
JPH10195063A (ja) * | 1996-10-21 | 1998-07-28 | Dai Ichi Seiyaku Co Ltd | エチニルチアゾール誘導体 |
EP1092711A4 (en) | 1998-07-01 | 2002-07-31 | Takeda Chemical Industries Ltd | RETINOID ASSOCIATED RECEPTOR REGULATORS |
AU3076700A (en) | 1999-01-26 | 2000-08-18 | Ono Pharmaceutical Co. Ltd. | 2h-phthalazin-1-one derivatives and drugs comprising these derivatives as the active ingredient |
UA71971C2 (en) | 1999-06-04 | 2005-01-17 | Agoron Pharmaceuticals Inc | Diaminothiazoles, composition based thereon, a method for modulation of protein kinases activity, a method for the treatment of diseases mediated by protein kinases |
AR035016A1 (es) | 1999-08-25 | 2004-04-14 | Takeda Chemical Industries Ltd | Composicion de azol promotor de produccion/secrecion de neurotrofina, compuesto prodroga del mismo, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima. |
FR2825706B1 (fr) * | 2001-06-06 | 2003-12-12 | Pf Medicament | Nouveaux derives de benzothienyle ou d'indole, leur preparation et leur utilisation comme inhibiteurs de proteines prenyl transferase |
JP2005518371A (ja) * | 2001-12-10 | 2005-06-23 | アムジエン・インコーポレーテツド | バニロイド受容体リガンド及び治療に於けるこれらの使用 |
US7183276B2 (en) | 2002-02-28 | 2007-02-27 | Takeda Pharmaceutical Company Limited | Azole compounds |
WO2003099793A1 (en) | 2002-05-24 | 2003-12-04 | Takeda Pharmaceutical Company Limited | 1,2-azole derivatives with hypoglycemic and hypolipidemic activity |
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-
2008
- 2008-05-15 JP JP2008128851A patent/JP2008231115A/ja not_active Abandoned
- 2008-07-01 CR CR10127A patent/CR10127A/es not_active Application Discontinuation
- 2008-07-15 US US12/219,073 patent/US20080287438A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
RU2337682C2 (ru) | 2008-11-10 |
CN1731994A (zh) | 2006-02-08 |
MXPA05004505A (es) | 2005-07-26 |
NO20052626D0 (no) | 2005-05-31 |
PE20040609A1 (es) | 2004-10-29 |
RU2005116689A (ru) | 2006-01-20 |
US7423159B2 (en) | 2008-09-09 |
CR7849A (es) | 2005-09-19 |
AR041867A1 (es) | 2005-06-01 |
EP1556032A1 (en) | 2005-07-27 |
CO5570666A2 (es) | 2005-10-31 |
JP2008231115A (ja) | 2008-10-02 |
ZA200503967B (en) | 2006-11-29 |
PL376733A1 (pl) | 2006-01-09 |
NZ540381A (en) | 2007-11-30 |
BR0315815A (pt) | 2005-09-13 |
US20080287438A1 (en) | 2008-11-20 |
AU2003278600A1 (en) | 2004-05-25 |
US20060004069A1 (en) | 2006-01-05 |
KR20050062645A (ko) | 2005-06-23 |
TW200416029A (en) | 2004-09-01 |
WO2004039365A1 (en) | 2004-05-13 |
CA2504511A1 (en) | 2004-05-13 |
CR10127A (es) | 2008-08-18 |
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