ATE496035T1 - Stickstoffenthaltende heterocyclische verbindungen - Google Patents
Stickstoffenthaltende heterocyclische verbindungenInfo
- Publication number
- ATE496035T1 ATE496035T1 AT99912061T AT99912061T ATE496035T1 AT E496035 T1 ATE496035 T1 AT E496035T1 AT 99912061 T AT99912061 T AT 99912061T AT 99912061 T AT99912061 T AT 99912061T AT E496035 T1 ATE496035 T1 AT E496035T1
- Authority
- AT
- Austria
- Prior art keywords
- atom
- substituted
- represent
- nitrogen
- unsubstituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8751498 | 1998-03-31 | ||
| PCT/JP1999/001665 WO1999051582A1 (en) | 1998-03-31 | 1999-03-31 | Nitrogenous heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE496035T1 true ATE496035T1 (de) | 2011-02-15 |
Family
ID=13917109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99912061T ATE496035T1 (de) | 1998-03-31 | 1999-03-31 | Stickstoffenthaltende heterocyclische verbindungen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6423716B1 (de) |
| EP (1) | EP1067123B1 (de) |
| AT (1) | ATE496035T1 (de) |
| AU (1) | AU3053999A (de) |
| CA (1) | CA2326324C (de) |
| DE (1) | DE69943144D1 (de) |
| ES (1) | ES2356886T3 (de) |
| WO (1) | WO1999051582A1 (de) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100345830C (zh) * | 2000-04-27 | 2007-10-31 | 安斯泰来制药有限公司 | 稠合杂芳基衍生物 |
| US6608053B2 (en) | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
| AU8066701A (en) | 2000-07-20 | 2002-02-05 | Neurogen Corp | Capsaicin receptor ligands |
| US6956039B2 (en) * | 2000-08-18 | 2005-10-18 | Millennium Pharmaceuticals, Inc. | Nitrogenous heterocylic compounds |
| EP2277877A1 (de) * | 2000-08-18 | 2011-01-26 | Millennium Pharmaceuticals, Inc. | Quinazolinderivate als Kinasehemmer |
| AU2001293208A1 (en) | 2000-08-18 | 2002-03-04 | Cor Therapeutics, Inc. | Nitrogenous heterocyclic compounds |
| DE60144284D1 (de) | 2000-11-01 | 2011-05-05 | Millennium Pharm Inc | Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung |
| US20040259881A1 (en) * | 2001-02-02 | 2004-12-23 | Anjali Pandey | Nitrogenous heterocyclic compounds |
| AU2002254152A1 (en) | 2001-03-08 | 2002-09-24 | Millennium Pharmaceuticals | (homo) piperazine substituted quinolines for inhibiting the phosphorylation of kinases |
| US20040106635A1 (en) * | 2001-03-29 | 2004-06-03 | Iwao Takamuro | Spiroisoquinoline compound, a method for preparing the same and an intermediate thereof |
| US6849638B2 (en) | 2001-04-30 | 2005-02-01 | Bayer Pharmaceuticals Corporation | 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same, and their use in the treatment or prevention of pde7b-mediated diseases and conditions |
| US20030211040A1 (en) | 2001-08-31 | 2003-11-13 | Paul Greengard | Phosphodiesterase activity and regulation of phosphodiesterase 1B-mediated signaling in brain |
| US6845657B2 (en) * | 2002-03-28 | 2005-01-25 | Harrison R. Cooper Systems, Inc. | Apparatus for sampling drill hole cuttings |
| IL165862A0 (en) * | 2002-06-28 | 2006-01-15 | Euro Celtique Sa | Therapeutic piperazine derivatives useful for tre ating pain |
| US7262194B2 (en) * | 2002-07-26 | 2007-08-28 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
| US7157462B2 (en) * | 2002-09-24 | 2007-01-02 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
| EP1567506A4 (de) * | 2002-11-20 | 2007-06-20 | Array Biopharma Inc | Cyanoguanidine und cyanoamidine als erbb2- und egfr-inhibitoren |
| US7488823B2 (en) | 2003-11-10 | 2009-02-10 | Array Biopharma, Inc. | Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors |
| EP1684694A2 (de) * | 2003-11-21 | 2006-08-02 | Array Biopharma, Inc. | Akt-protein-kinase-hemmer |
| JP5274842B2 (ja) * | 2004-12-28 | 2013-08-28 | エグゼリクシス， インコーポレイテッド | 免疫疾患、炎症疾患および増殖疾患の処置のためのセリン−スレオニンキナーゼモジュレーター（ｐ７０Ｓ６Ｋ、Ａｋｔ−１およびＡｋｔ−２）としての［１Ｈ−ピペラゾ［３，４−ｄ］ピリミジン−４−イル］−ピペラジンまたは［１Ｈ−ピペラゾ［３，４−ｄ］ピリミジン−４−イル］−ピペラジン化合物 |
| FR2880540B1 (fr) * | 2005-01-13 | 2008-07-11 | Aventis Pharma Sa | Utilisation de derives de la purine comme inhibiteurs de la proteine hsp90 |
| JP5084725B2 (ja) | 2005-06-06 | 2012-11-28 | 武田薬品工業株式会社 | 有機化合物 |
| US20080194592A1 (en) * | 2005-08-23 | 2008-08-14 | Intra-Cellular Therapies, Inc. | Organic Compounds |
| US20070265270A1 (en) * | 2006-02-21 | 2007-11-15 | Hitchcock Stephen A | Cinnoline derivatives as phosphodiesterase 10 inhibitors |
| JP2009529060A (ja) * | 2006-03-08 | 2009-08-13 | アムゲン インコーポレイティッド | ホスホジエステラーゼ１０阻害剤としてのキノリン及びイソキノリン誘導体 |
| US8252792B2 (en) | 2006-04-26 | 2012-08-28 | F. Hoffman-La Roche Ag | Pyrimidine derivatives as PI3K inhibitors |
| PL2041139T3 (pl) | 2006-04-26 | 2012-05-31 | Hoffmann La Roche | Związki farmaceutyczne |
| US20080076924A1 (en) * | 2006-06-30 | 2008-03-27 | Patrick Betschmann | Piperazines as P2X7 antagonists |
| DE602007011628D1 (de) | 2006-07-06 | 2011-02-10 | Array Biopharma Inc | Dihydrofuropyrimidine als akt-proteinkinaseinhibitoren |
| US8063050B2 (en) | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| EP2054418B1 (de) | 2006-07-06 | 2011-11-09 | Array Biopharma Inc. | Dihydrothienopyrimidine als akt-proteinkinase-inhibitoren |
| CA2656618C (en) * | 2006-07-06 | 2014-08-26 | Array Biopharma Inc. | Cyclopenta [d] pyrimidines as akt protein kinase inhibitors |
| EP2081431B1 (de) * | 2006-11-13 | 2013-01-16 | Intra-Cellular Therapies, Inc. | Organische verbindungen |
| JP5837278B2 (ja) | 2006-12-05 | 2015-12-24 | イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． | 新規使用 |
| JP5462633B2 (ja) | 2007-01-16 | 2014-04-02 | パーデュー、ファーマ、リミテッド、パートナーシップ | 複素環置換ピペリジン化合物とその使用 |
| US8846683B2 (en) | 2007-07-05 | 2014-09-30 | Array Biopharma, Inc. | Pyrimidyl cyclopentanes as Akt protein kinase inhibitors |
| US9409886B2 (en) | 2007-07-05 | 2016-08-09 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| AR067413A1 (es) | 2007-07-05 | 2009-10-07 | Genentech Inc | Compuestos heterociclicos que contienen ciclopenta[d]pirimidina inhibidores de proteinquinasas akt, composiciones farmaceuticas que los contienen, metodo de preparacion y uso de las mismas para el tratamiento de enfermedades hiperproliferativas, tales como cancer |
| ES2533557T3 (es) * | 2007-07-05 | 2015-04-13 | Array Biopharma, Inc. | Pirimidil ciclopentanos como inhibidores de proteína cinasa AKT |
| JP5554709B2 (ja) | 2007-08-31 | 2014-07-23 | パーデュー、ファーマ、リミテッド、パートナーシップ | 置換キノキサリンタイプピペリジン化合物とその使用 |
| GB0721095D0 (en) * | 2007-10-26 | 2007-12-05 | Piramed Ltd | Pharmaceutical compounds |
| US7946206B2 (en) * | 2007-11-21 | 2011-05-24 | Rocksmart, Llc | Quick-release system |
| JP5701608B2 (ja) * | 2007-12-06 | 2015-04-15 | イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． | 有機化合物 |
| US8841304B2 (en) | 2008-01-08 | 2014-09-23 | Array Biopharma, Inc. | Pyrrolopyridines as kinase inhibitors |
| WO2009089459A1 (en) * | 2008-01-09 | 2009-07-16 | Array Biopharma Inc. | Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors |
| MX2010007546A (es) * | 2008-01-09 | 2010-09-30 | Array Biopharma Inc | Pirimidil ciclopentanos hidroxilados en forma de inhibidores de akt proteína quinasa. |
| ES2392014T3 (es) | 2008-01-09 | 2012-12-03 | Array Biopharma, Inc. | Pirazolopiridinas como inhibidores de la cinasa |
| ES2393849T7 (es) | 2008-07-21 | 2015-01-28 | Purdue Pharma Lp | Compuestos de piperidina puenteada, de tipo quinoxalina sustituida, y usos de los mismos |
| EP2370417A2 (de) * | 2008-11-21 | 2011-10-05 | Millennium Pharmaceuticals, Inc. | Lactatsalz von 4-[6-methoxy-7-(3-piperidin-1-yl-propoxy)chinazolin-4-yl]piperazin-1-carbonsäure-(4-isopropoxyphenyl)amid und pharmazeutische zusammensetzungen davon zur behandlung von krebs und anderen krankheiten bzw. störungen |
| EP2367430B1 (de) | 2008-12-06 | 2014-08-13 | Intra-Cellular Therapies, Inc. | Organische verbindungen |
| BRPI0922809A2 (pt) | 2008-12-06 | 2018-05-29 | Intracellular Therapies Inc | compostos orgânicos |
| EA201170773A1 (ru) | 2008-12-06 | 2012-01-30 | Интра-Селлулар Терапиз, Инк. | Органические соединения |
| US11464781B2 (en) | 2009-02-25 | 2022-10-11 | Intra-Cellular Therapies, Inc. | PDE1 inhibitors for ophthalmic disorders |
| JP2012526810A (ja) | 2009-05-13 | 2012-11-01 | イントラ−セルラー・セラピーズ・インコーポレイテッド | 有機化合物 |
| SG10201507362TA (en) | 2009-08-05 | 2015-10-29 | Intra Cellular Therapies Inc | Novel Regulatory Proteins And Inhibitors |
| EP2590657A4 (de) | 2010-05-31 | 2014-02-12 | Intra Cellular Therapies Inc | Organische verbindungen |
| US9434730B2 (en) | 2010-05-31 | 2016-09-06 | Intra-Cellular Therapies, Inc. | PDE1 inhibitor compounds |
| JP5954838B2 (ja) * | 2010-09-14 | 2016-07-20 | エクセリクシス， インク． | Ｐｉ３ｋ−デルタの阻害剤ならびにそれらの使用法および製造法 |
| CN103841976A (zh) | 2011-04-01 | 2014-06-04 | 基因泰克公司 | Akt和mek抑制剂化合物的组合及其使用方法 |
| CN103841975A (zh) | 2011-04-01 | 2014-06-04 | 基因泰克公司 | Akt抑制剂化合物和厄洛替尼的组合以及使用方法 |
| MX2014015648A (es) | 2012-06-28 | 2015-08-05 | Abbvie Inc | Cianoguanidinas y usos de las mismas. |
| WO2014086453A1 (en) * | 2012-12-07 | 2014-06-12 | Merck Patent Gmbh | Azaheterobicyclic compounds |
| US9714248B2 (en) * | 2012-12-20 | 2017-07-25 | Ucb Pharma S.A. | Therapeutically active pyrazolo-pyrimidine derivatives |
| USRE48622E1 (en) | 2012-12-20 | 2021-07-06 | UCB Biopharma SRL | Therapeutically active pyrazolo-pyrimidine derivatives |
| WO2014102594A2 (en) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Substituted benzimidazole-type piperidine compounds and uses thereof |
| EP2956141A4 (de) | 2013-02-17 | 2016-10-26 | Intra Cellular Therapies Inc | Neuartige verwendungen |
| PL2970279T3 (pl) | 2013-03-15 | 2021-05-31 | Intra-Cellular Therapies, Inc. | Związki organiczne |
| EP2968338B1 (de) | 2013-03-15 | 2019-01-09 | Intra-Cellular Therapies, Inc. | Pde1-inhibitoren zur verwendung bei der behandlung und/oder prävention von zns-verletzungen und pns-krankheiten, störungen oder verletzungen |
| DK3157926T3 (da) | 2014-06-20 | 2019-08-19 | Intra Cellular Therapies Inc | Organiske forbindelser |
| US9546175B2 (en) | 2014-08-07 | 2017-01-17 | Intra-Cellular Therapies, Inc. | Organic compounds |
| US10285992B2 (en) | 2014-08-07 | 2019-05-14 | Intra-Cellular Therapies, Inc. | Combinations of PDE1 inhibitors and NEP inhibitors and associated methods |
| US10131671B2 (en) | 2014-08-07 | 2018-11-20 | Intra-Cellular Therapies, Inc. | Organic compounds |
| RU2711442C2 (ru) | 2014-09-17 | 2020-01-17 | Интра-Селлулар Терапиз, Инк. | Соединения и способы |
| US10682354B2 (en) | 2016-03-28 | 2020-06-16 | Intra-Cellular Therapies, Inc. | Compositions and methods |
| EP3509589B1 (de) | 2016-09-12 | 2021-11-17 | Intra-Cellular Therapies, Inc. | Neuartige verwendungen |
| US11839614B2 (en) | 2018-01-31 | 2023-12-12 | Intra-Cellular Therapies, Inc. | Methods for treating or mitigating cardiotoxicity characterized by inhibition of adenosine A2 signaling and/or adenosine A2 receptor expression |
| JP7612672B2 (ja) | 2019-09-03 | 2025-01-14 | イントラ－セルラー・セラピーズ・インコーポレイテッド | 新規化合物 |
| US12364695B2 (en) | 2020-06-02 | 2025-07-22 | Intra-Cellular Therapies, Inc. | Methods of treating inflammatory disease |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO128657B (de) * | 1966-10-31 | 1973-12-27 | Pfizer | |
| US3723434A (en) * | 1970-07-17 | 1973-03-27 | Pfizer | Piperazino isoquinoline bronchodilators |
| SU474984A3 (ru) * | 1971-04-10 | 1975-06-25 | Д-Р Карл Томэ Гмбх (Фирма) | Способ получени пиридо (3,2- ) пиримидинов |
| JPS58172379A (ja) * | 1982-04-02 | 1983-10-11 | Showa Denko Kk | 新規なキナゾリン誘導体 |
| IL87149A (en) | 1987-07-20 | 1994-05-30 | Merck & Co Inc | 6-Piperazinyl derivatives of purine and its 3- and 9-deaza isosteres, their preparation and pharmaceutical compositions containing them |
| AU658646B2 (en) | 1991-05-10 | 1995-04-27 | Rhone-Poulenc Rorer International (Holdings) Inc. | Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
| NZ243082A (en) | 1991-06-28 | 1995-02-24 | Ici Plc | 4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof |
| US5521184A (en) | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| JP3229693B2 (ja) * | 1993-02-22 | 2001-11-19 | 協和醗酵工業株式会社 | ピペラジン誘導体 |
| US5656643A (en) | 1993-11-08 | 1997-08-12 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
| US5654307A (en) | 1994-01-25 | 1997-08-05 | Warner-Lambert Company | Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family |
| EP0682027B1 (de) | 1994-05-03 | 1997-10-15 | Novartis AG | Pyrrolopyrimidinderivate mit antiproliferativer Wirkung |
| GB9510757D0 (en) | 1994-09-19 | 1995-07-19 | Wellcome Found | Therapeuticaly active compounds |
| AU711592B2 (en) | 1995-04-03 | 1999-10-14 | Novartis Ag | Pyrazole derivatives and processes for the preparation thereof |
| CA2223081C (en) | 1995-06-07 | 2001-03-06 | Pfizer Inc. | Heterocyclic ring-fused pyrimidine derivatives |
| ATE212993T1 (de) | 1995-07-06 | 2002-02-15 | Novartis Erfind Verwalt Gmbh | Pyrolopyrimidine und verfahren zu ihrer herstellung |
| AR004010A1 (es) | 1995-10-11 | 1998-09-30 | Glaxo Group Ltd | Compuestos heterociclicos |
| WO1997017329A1 (en) | 1995-11-07 | 1997-05-15 | Kirin Beer Kabushiki Kaisha | Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same |
| US6140317A (en) | 1996-01-23 | 2000-10-31 | Novartis Ag | Pyrrolopyrimidines and processes for their preparation |
| AU719392B2 (en) * | 1996-10-01 | 2000-05-11 | Kyowa Hakko Kirin Co., Ltd. | Nitrogen-containing heterocyclic compounds |
-
1999
- 1999-03-31 ES ES99912061T patent/ES2356886T3/es not_active Expired - Lifetime
- 1999-03-31 AU AU30539/99A patent/AU3053999A/en not_active Abandoned
- 1999-03-31 EP EP99912061A patent/EP1067123B1/de not_active Expired - Lifetime
- 1999-03-31 DE DE69943144T patent/DE69943144D1/de not_active Expired - Lifetime
- 1999-03-31 US US09/647,490 patent/US6423716B1/en not_active Expired - Lifetime
- 1999-03-31 CA CA2326324A patent/CA2326324C/en not_active Expired - Fee Related
- 1999-03-31 WO PCT/JP1999/001665 patent/WO1999051582A1/ja not_active Ceased
- 1999-03-31 AT AT99912061T patent/ATE496035T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1067123A4 (de) | 2002-04-03 |
| CA2326324C (en) | 2010-05-11 |
| ES2356886T3 (es) | 2011-04-14 |
| AU3053999A (en) | 1999-10-25 |
| US6423716B1 (en) | 2002-07-23 |
| EP1067123B1 (de) | 2011-01-19 |
| EP1067123A1 (de) | 2001-01-10 |
| DE69943144D1 (de) | 2011-03-03 |
| CA2326324A1 (en) | 1999-10-14 |
| WO1999051582A1 (en) | 1999-10-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE496035T1 (de) | Stickstoffenthaltende heterocyclische verbindungen | |
| NO953305D0 (no) | Antranilsyrederivat | |
| ATE480521T1 (de) | Stickstoff enthaltende heterocyclische verbindungen | |
| AU2001230564A1 (en) | Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same | |
| ATE368655T1 (de) | Stickstoffhaltige heterocyclische verbindung und arzneimittel davon | |
| CR7727A (es) | Compuestos quimicos | |
| ATE206412T1 (de) | Heterocyclische verbindungen als bradykinin antagonisten | |
| DE60140860D1 (de) | 2-aminonicotinamid-derivate und ihre verwendung als vegf-rezeptor tyrosin-kinase inhibitoren | |
| DK0976748T3 (da) | Pyrrolidinderivater med phospholispase A2-hæmmende aktivitet | |
| GR3006247T3 (de) | ||
| WO2002028853A1 (en) | Benzylamine compound, process for producing the same, and intermediate therefor | |
| CA2273303A1 (en) | Thienylsulfonylamino(thio)carbonyl compounds | |
| EP1122253A4 (de) | Quinalozinon-derivate | |
| DE69915471D1 (de) | Analoga von distamycin-zimtsäurederivaten, verfahren zu ihrer herstellung und ihre verwendung als antitumormittel | |
| IL136510A (en) | Acylated hetero-alicyclic derivatives and pharmaceutical compositions containing the same | |
| NO20053302L (no) | Imidazolderivater med affinitet for alfa 2-reseptoraktivitet. | |
| DE60239324D1 (de) | Phenyl- und pyridyl-piperidine mit tnf-wirkung | |
| TR199901102T2 (xx) | Bisiklik amin t�revleri. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |