NO20022481D0 - NPYY5 antagonister - Google Patents
NPYY5 antagonisterInfo
- Publication number
- NO20022481D0 NO20022481D0 NO20022481A NO20022481A NO20022481D0 NO 20022481 D0 NO20022481 D0 NO 20022481D0 NO 20022481 A NO20022481 A NO 20022481A NO 20022481 A NO20022481 A NO 20022481A NO 20022481 D0 NO20022481 D0 NO 20022481D0
- Authority
- NO
- Norway
- Prior art keywords
- optionally substituted
- alkyl
- alkylene
- neuropeptide
- cycloalkyl
- Prior art date
Links
Classifications
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
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- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
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- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
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- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
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- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
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JP33646999 | 1999-11-26 | ||
JP35378699 | 1999-12-14 | ||
PCT/JP2000/008197 WO2001037826A1 (fr) | 1999-11-26 | 2000-11-21 | Antagonistes npyy5 |
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JP (1) | JP3910446B2 (no) |
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Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60040021D1 (de) * | 1999-11-26 | 2008-10-02 | Shionogi & Co | Npyy5-antagonisten |
US6894063B2 (en) | 2000-09-14 | 2005-05-17 | Schering Corporation | Substituted urea neuropeptide Y Y5 Receptor antagonists |
US6946476B2 (en) | 2000-12-21 | 2005-09-20 | Schering Corporation | Heteroaryl urea neuropeptide Y Y5 receptor antagonists |
IL156157A0 (en) | 2000-12-21 | 2003-12-23 | Schering Corp | Heteroaryl urea neuropeptide y y5 receptor antagonists |
US7067539B2 (en) | 2001-02-08 | 2006-06-27 | Schering Corporation | Cannabinoid receptor ligands |
US7507767B2 (en) | 2001-02-08 | 2009-03-24 | Schering Corporation | Cannabinoid receptor ligands |
GB0121709D0 (en) * | 2001-09-07 | 2001-10-31 | Imp College Innovations Ltd | Food inhibition agent |
DE60230818D1 (de) * | 2001-09-24 | 2009-02-26 | Imp Innovations Ltd | Pyy3-36 zur zur reduzierung oder vorbeugung von fettleibigkeit |
IL161439A0 (en) | 2001-11-14 | 2004-09-27 | Schering Corp | Cannabinoid receptor ligands |
US8058233B2 (en) * | 2002-01-10 | 2011-11-15 | Oregon Health And Science University | Modification of feeding behavior using PYY and GLP-1 |
MXPA04008728A (es) * | 2002-03-12 | 2004-12-06 | Shionogi & Co | Procedimiento para producir derivados de acido trans-4-amino-1-ciclohexanocarboxilico. |
JP2005533809A (ja) | 2002-06-19 | 2005-11-10 | シェーリング コーポレイション | カンナビノイドレセプタアゴニスト |
AR040335A1 (es) * | 2002-06-26 | 2005-03-30 | Glaxo Group Ltd | Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto |
TW200409637A (en) | 2002-06-26 | 2004-06-16 | Glaxo Group Ltd | Compounds |
US7166575B2 (en) * | 2002-12-17 | 2007-01-23 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of peptide YY and methods for treating and preventing obesity |
GB0300571D0 (en) * | 2003-01-10 | 2003-02-12 | Imp College Innovations Ltd | Modification of feeding behaviour |
AR043633A1 (es) | 2003-03-20 | 2005-08-03 | Schering Corp | Ligandos de receptores de canabinoides |
GB0312609D0 (en) * | 2003-06-02 | 2003-07-09 | Astrazeneca Ab | Novel compounds |
WO2005080348A1 (ja) * | 2004-02-19 | 2005-09-01 | Banyu Pharmaceutical Co., Ltd. | 新規スルホンアミド誘導体 |
US7534892B2 (en) | 2004-06-24 | 2009-05-19 | Shionogi & Co., Ltd. | Sulfonamide compound |
ATE472531T1 (de) * | 2004-08-06 | 2010-07-15 | Merck Sharp & Dohme | Sulfonylverbindungen als hemmer von 11-beta- hydroxysteroiddehydrogenase-1 |
DE102004039789A1 (de) | 2004-08-16 | 2006-03-02 | Sanofi-Aventis Deutschland Gmbh | Arylsubstituierte polycyclische Amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
TW200630337A (en) * | 2004-10-14 | 2006-09-01 | Euro Celtique Sa | Piperidinyl compounds and the use thereof |
BRPI0607308A2 (pt) * | 2005-01-25 | 2009-08-25 | Synta Pharmaceuticals Corp | compostos, composições farmacêuticas e usos dos referidos compostos |
BRPI0609529A2 (pt) * | 2005-03-31 | 2010-04-13 | Shionogi & Co | processo para a preparação de compostos derivados de sulfamato-carboxilato e composto |
GB0511986D0 (en) * | 2005-06-13 | 2005-07-20 | Imp College Innovations Ltd | Novel compounds and their effects on feeding behaviour |
US20060293341A1 (en) * | 2005-06-23 | 2006-12-28 | Vrej Jubian | Alkyl sulfonamide derivatives |
EP1991528A2 (en) * | 2006-01-18 | 2008-11-19 | Siena Biotech S.p.A. | Modulators of alpha7 nicotinic acetylcholine receptors and therapeutic uses thereof |
TW200800979A (en) * | 2006-03-07 | 2008-01-01 | Lundbeck & Co As H | Halogenated sulfonamide derivatives |
WO2007110449A1 (en) | 2006-03-29 | 2007-10-04 | Euro-Celtique S.A. | Benzenesulfonamide compounds and their use |
WO2007118854A1 (en) * | 2006-04-13 | 2007-10-25 | Euro-Celtique S.A. | Benzenesulfonamide compounds and the use thereof |
US8791264B2 (en) | 2006-04-13 | 2014-07-29 | Purdue Pharma L.P. | Benzenesulfonamide compounds and their use as blockers of calcium channels |
US9150507B2 (en) | 2006-04-28 | 2015-10-06 | Shionogi & Co., Ltd. | Amine derivative having NPY Y5 receptor antagonistic activity |
DE102006039003A1 (de) | 2006-08-19 | 2008-02-21 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Verbindungen |
WO2008026564A1 (fr) | 2006-08-30 | 2008-03-06 | Shionogi & Co., Ltd. | Dérivés d'urée |
JP5187901B2 (ja) * | 2006-08-30 | 2013-04-24 | 塩野義製薬株式会社 | ヒドラジンアミド誘導体 |
JP5235887B2 (ja) | 2006-09-20 | 2013-07-10 | アエリー ファーマシューティカルズ インコーポレイテッド | Rhoキナーゼ阻害剤 |
JP5019396B2 (ja) * | 2006-10-18 | 2012-09-05 | 塩野義製薬株式会社 | 糖代謝改善剤 |
TWI428346B (zh) * | 2006-12-13 | 2014-03-01 | Imp Innovations Ltd | 新穎化合物及其等對進食行為影響 |
US8455513B2 (en) | 2007-01-10 | 2013-06-04 | Aerie Pharmaceuticals, Inc. | 6-aminoisoquinoline compounds |
MX2009010059A (es) | 2007-03-22 | 2009-10-12 | Astrazeneca Ab | Derivados de quinolina para el tratamiento de enfermedades inflamatorias. |
WO2008124118A1 (en) | 2007-04-09 | 2008-10-16 | Purdue Pharma L.P. | Benzenesulfonyl compounds and the use therof |
MX2010001664A (es) | 2007-08-14 | 2010-03-10 | Boehringer Ingelheim Int | Nuevos compuestos. |
EP2025675A1 (de) | 2007-08-14 | 2009-02-18 | Boehringer Ingelheim International GmbH | Arylsulfonamide mit analgetischer Wirkung |
WO2009038112A1 (ja) | 2007-09-21 | 2009-03-26 | Shionogi & Co., Ltd. | Npyy5受容体拮抗剤を含有する固形製剤 |
US8765736B2 (en) * | 2007-09-28 | 2014-07-01 | Purdue Pharma L.P. | Benzenesulfonamide compounds and the use thereof |
SA08290668B1 (ar) | 2007-10-25 | 2012-02-12 | شيونوجي آند كو.، ليمتد | مشتقات أمين لها نشاط مضاد لمستقبل npy y5 واستخداماتها |
PE20091036A1 (es) | 2007-11-30 | 2009-08-15 | Astrazeneca Ab | Derivado de quinolina como antagonista del receptor p2x7 |
US8455514B2 (en) * | 2008-01-17 | 2013-06-04 | Aerie Pharmaceuticals, Inc. | 6-and 7-amino isoquinoline compounds and methods for making and using the same |
CL2009000904A1 (es) | 2008-04-21 | 2010-04-30 | Shionogi & Co | Compuestos derivados de ciclohexil sulfonamidas que tienen actividad antagonista en el receptor npy y5, composicion farmaceutica y formulacion farmaceutica que los comprende. |
CL2009001088A1 (es) * | 2008-05-08 | 2011-06-17 | Shionogi & Co | Forma cristalina (ii) de (1r,4r)-4-(1,1-dimetiletilsulfonamido)-n-(5-(trifluorometil) piridin-2-il) ciclohexancarboxamida; procesos de preparacion; utiles como antagonistas del receptor npyy5. |
US8450344B2 (en) | 2008-07-25 | 2013-05-28 | Aerie Pharmaceuticals, Inc. | Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds |
CN102272120B (zh) * | 2008-11-07 | 2013-12-25 | H.隆德贝克有限公司 | 生物活性酰胺 |
WO2010098298A1 (ja) * | 2009-02-27 | 2010-09-02 | 塩野義製薬株式会社 | 栄養素の消化吸収抑制作用を有する化合物とシクロヘキサンカルボキサミド誘導体を組み合わせてなる医薬組成物 |
EP2404896A1 (en) * | 2009-03-05 | 2012-01-11 | Shionogi&Co., Ltd. | Cyclohexane derivative having npy y5 receptor antagonism |
JP5642661B2 (ja) * | 2009-03-05 | 2014-12-17 | 塩野義製薬株式会社 | Npyy5受容体拮抗作用を有するピペリジンおよびピロリジン誘導体 |
WO2010107040A1 (ja) * | 2009-03-19 | 2010-09-23 | 塩野義製薬株式会社 | Npyy5受容体拮抗剤を含有する固形製剤 |
US8227618B2 (en) | 2009-04-23 | 2012-07-24 | Shionogi & Co., Ltd. | Amine-derivatives having NPY Y5 receptor antagonistic activity and the uses thereof |
CA2929545C (en) | 2009-05-01 | 2019-04-09 | Aerie Pharmaceuticals, Inc. | Dual mechanism inhibitors for the treatment of disease |
WO2011058943A1 (ja) * | 2009-11-11 | 2011-05-19 | 塩野義製薬株式会社 | Mch r1アンタゴニスト活性を有する化合物とnpy y5受容体アンタゴニスト活性を有する化合物を組み合わせてなる医薬組成物 |
US8946197B2 (en) | 2009-11-16 | 2015-02-03 | Chdi Foundation, Inc. | Transglutaminase TG2 inhibitors, pharmaceutical compositions, and methods of use thereof |
US8394858B2 (en) | 2009-12-03 | 2013-03-12 | Novartis Ag | Cyclohexane derivatives and uses thereof |
BR112013027342A2 (pt) * | 2011-04-27 | 2017-01-17 | Shionogi & Co | derivados heteroaromáticos com 5 membros no anel tendo atividade antagonista para o receptor y5 de npy |
US8889716B2 (en) | 2011-05-10 | 2014-11-18 | Chdi Foundation, Inc. | Transglutaminase TG2 inhibitors, pharmaceutical compositions, and methods of use thereof |
WO2013002313A1 (ja) * | 2011-06-29 | 2013-01-03 | 塩野義製薬株式会社 | 体重管理薬 |
US10092574B2 (en) | 2012-09-26 | 2018-10-09 | Valorisation-Recherche, Limited Partnership | Inhibitors of polynucleotide repeat-associated RNA foci and uses thereof |
BR112015010186A2 (pt) | 2012-11-05 | 2017-07-11 | Nant Holdings Ip Llc | sulfonamida cíclica contendo derivados como inibidores da via de sinalização de hedgehog |
ES2852377T3 (es) | 2013-03-15 | 2021-09-13 | Aerie Pharmaceuticals Inc | Sales dimesilato de 4-(3-amino-1-(isoquinolin-6-ilamino)-1-oxopropan-2-il)bencilo, sus combinaciones con prostaglandinas y el uso de las mismas en el tratamiento de trastornos oculares |
WO2015187673A1 (en) | 2014-06-02 | 2015-12-10 | Afshari Thomas | Linear actuator assembly and system |
US9765050B2 (en) | 2014-12-30 | 2017-09-19 | Novira Therapeutics, Inc. | Pyridyl reverse sulfonamides for HBV treatment |
CN108601355B (zh) | 2015-11-17 | 2021-03-30 | 爱瑞制药公司 | 制备激酶抑制剂及其中间体的方法 |
US9643927B1 (en) | 2015-11-17 | 2017-05-09 | Aerie Pharmaceuticals, Inc. | Process for the preparation of kinase inhibitors and intermediates thereof |
CN108602758B (zh) | 2016-02-05 | 2021-01-26 | 斯福瑞股份公司 | 制备反式-4-氨基-1-环己烷基羧酸及其衍生物的方法 |
WO2018045091A1 (en) | 2016-08-31 | 2018-03-08 | Aerie Pharmaceuticals, Inc. | Ophthalmic compositions |
DK3483164T3 (da) | 2017-03-20 | 2020-03-23 | Forma Therapeutics Inc | Pyrrolopyrrolsammensætninger som pyruvatkinase (pkr) aktivatorer |
CA3057872A1 (en) | 2017-03-31 | 2018-10-04 | Aerie Pharmaceuticals, Inc. | Aryl cyclopropyl-amino-isoquinolinyl amide compounds |
US11427563B2 (en) | 2018-09-14 | 2022-08-30 | Aerie Pharmaceuticals, Inc. | Aryl cyclopropyl-amino-isoquinolinyl amide compounds |
US20220031671A1 (en) | 2018-09-19 | 2022-02-03 | Forma Therapeutics, Inc. | Treating sickle cell disease with a pyruvate kinase r activating compound |
US20230055923A1 (en) | 2018-09-19 | 2023-02-23 | Forma Therapeutics, Inc. | Activating pyruvate kinase r |
Family Cites Families (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3704290A (en) | 1970-12-09 | 1972-11-28 | American Home Prod | 6-(1 - substituted aminocycloalkane-carboxamido)-penicillanic acid and salts |
JPS5916871A (ja) * | 1982-07-20 | 1984-01-28 | Shionogi & Co Ltd | スルホンアミド系ベンズアミド類 |
AU567140B2 (en) * | 1984-01-06 | 1987-11-12 | Shionogi & Co., Ltd. | Sulphonamido-benzamide derivatives |
DE3535167A1 (de) | 1985-10-02 | 1987-04-09 | Boehringer Mannheim Gmbh | Neue sulfonyl-phenyl(alkyl)amine, verfahren zu ihrer herstellung sowie arzneimittel |
CA1278577C (en) | 1985-11-18 | 1991-01-02 | Tatsuo Tsuri | Bicyclic sulfonamide derivatives |
JP2565746B2 (ja) | 1987-10-23 | 1996-12-18 | 小野薬品工業株式会社 | 新規な炭素環系スルホンアミド誘導体 |
US5378691A (en) * | 1988-04-14 | 1995-01-03 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Amino acid derivatives |
DE3821540A1 (de) | 1988-06-25 | 1989-12-28 | Boehringer Mannheim Gmbh | Neue sulfonamide, verfahren zu ihrer herstellung sowie solche sulfonamide enthaltende arzneimittel |
US5189211A (en) | 1990-08-01 | 1993-02-23 | Taisho Pharmaceutical Co., Ltd. | Sulfonamide derivatives |
JP3052010B2 (ja) | 1991-07-18 | 2000-06-12 | 本田技研工業株式会社 | 摺動部材 |
JPH05194370A (ja) | 1992-01-22 | 1993-08-03 | Taisho Pharmaceut Co Ltd | スルホンアミド誘導体 |
JPH05262643A (ja) | 1992-01-23 | 1993-10-12 | Taisho Pharmaceut Co Ltd | トロンボキサンa2拮抗剤 |
US5506242A (en) | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
NZ288299A (en) | 1994-06-22 | 1998-06-26 | British Biotech Pharm | Substituted (hetero)aryl-sulphonylaminomethyl-hydroxamic acid and medicaments |
FI97148C (fi) | 1994-07-14 | 1996-10-25 | Lahden Polttimo Ab Oy | Menetelmä kasvien käsittelemiseksi siementen laatuominaisuuksien parantamiseksi |
JPH0892249A (ja) | 1994-07-20 | 1996-04-09 | Sankyo Co Ltd | スルホンアミド誘導体 |
US6172113B1 (en) | 1995-06-21 | 2001-01-09 | Shionogi & Co., Ltd. | Bicyclic amino derivatives and PGD2 antagonist containing the same |
KR980009238A (ko) | 1995-07-28 | 1998-04-30 | 우에노 도시오 | 설포닐아미노산 유도체 |
EP0858457A1 (de) | 1995-10-20 | 1998-08-19 | Dr. Karl Thomae GmbH | 5-gliedrige heterocyclen, diese verbindungen enthaltende arzneimittel und deren verwendung sowie verfahren zu ihrer herstellung |
AU7692696A (en) * | 1995-12-01 | 1997-06-27 | Novartis Ag | Heteroaryl derivatives |
AU7692996A (en) | 1995-12-01 | 1997-06-27 | Ciba-Geigy Ag | Receptor antagonists |
AU1328197A (en) | 1995-12-01 | 1997-06-19 | Synaptic Pharmaceutical Corporation | Aryl sulfonamide and sulfamide derivatives and uses thereof |
WO1997020820A1 (en) * | 1995-12-01 | 1997-06-12 | Novartis Ag | Heteroaryl compounds |
KR100338857B1 (ko) | 1996-01-23 | 2002-05-30 | 시오노 요시히코 | 술폰화 아미노산 유도체 및 이를 함유한메탈로프로테이나제 저해제 |
EP0882029B1 (en) | 1996-02-02 | 2003-04-02 | Merck & Co., Inc. | Heterocyclic derivatives as antidiabetic and antiobesity agents |
PL186416B1 (pl) | 1996-05-17 | 2004-01-30 | Warner Lambert Co | Związek bifenylosulfonamidowy i preparat farmaceutyczny zawierający ten związek |
AU2792097A (en) | 1996-05-24 | 1998-01-05 | Ono Pharmaceutical Co. Ltd. | Phenylsulfonamide derivatives |
CO5011105A1 (es) * | 1997-12-22 | 2001-02-28 | Novartis Ag | Compuestos organicos para tratar la obesidad y desordenes relacionados, composiciones farmaceuticas que los comprenden y procesos para su preparacion |
PT1076644E (pt) * | 1998-04-29 | 2004-10-29 | Ortho Mcneil Pharm Inc | Aminotetralinas substituidas emn como ligandos para o receptor de neuropeptideoy y5 util no tratamento da obesidade e de outras perturbacoes |
JP2002517483A (ja) | 1998-06-08 | 2002-06-18 | シェーリング コーポレイション | 神経ペプチドy5レセプターアンタゴニスト |
DE19830431A1 (de) | 1998-07-08 | 2000-01-13 | Hoechst Marion Roussel De Gmbh | Sulfonylamino-carbonsäure-N-arylamide als Guanylatcyclase-Aktivatoren |
ES2251200T3 (es) * | 1998-07-08 | 2006-04-16 | Sanofi-Aventis Deutschland Gmbh | N-arilamidas del acido sulfonilaminocarboxilico sustituidas con azufre, su uso y preparaciones farmaceuticas que las comprenden. |
ES2161594B1 (es) | 1998-12-17 | 2003-04-01 | Servier Lab | Nuevos derivados de la hidrazida, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. |
EP1184373A4 (en) | 1999-04-20 | 2004-10-20 | Meiji Seika Kaisha | TRICYCLIC CONNECTIONS |
PT1183245E (pt) | 1999-04-22 | 2007-07-12 | Lundbeck & Co As H | Antagonistas selectivos de npy (y5) |
US6124331A (en) * | 1999-06-30 | 2000-09-26 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (tricyclics) |
CA2373035A1 (en) | 1999-05-05 | 2000-11-16 | Scott Dax | 3a,4,5,9b-tetrahydro-1h-benz[e]indol-2-yl amine-derived neuropeptide y receptors ligands useful in the treatment of obesity and other disorders |
DK1194421T3 (da) | 1999-06-30 | 2006-02-13 | Lundbeck & Co As H | Selektive NPY (Y5) antagonister |
WO2001007409A1 (en) | 1999-07-23 | 2001-02-01 | Astrazeneca Uk Limited | Carbazole derivatives and their use as neuropeptide y5 receptor ligands |
JP2003506367A (ja) | 1999-07-28 | 2003-02-18 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 肥満症および他の障害の処置に有用な神経ペプチドyy5レセプターのリガンドとしてのアミンおよびアミド誘導体 |
JP2001172257A (ja) | 1999-10-05 | 2001-06-26 | Fujisawa Pharmaceut Co Ltd | 有機スルホンアミド化合物 |
CA2387493A1 (en) * | 1999-10-08 | 2001-04-19 | Lorin Andrew Thompson | Amino lactam sulfonamides as inhibitors of a.beta. protein production |
JP2001122865A (ja) | 1999-10-27 | 2001-05-08 | Meiji Seika Kaisha Ltd | ベンゾチアゾロン誘導体 |
DE60040021D1 (de) | 1999-11-26 | 2008-10-02 | Shionogi & Co | Npyy5-antagonisten |
MXPA04008728A (es) | 2002-03-12 | 2004-12-06 | Shionogi & Co | Procedimiento para producir derivados de acido trans-4-amino-1-ciclohexanocarboxilico. |
TW200422280A (en) * | 2002-12-11 | 2004-11-01 | Asahi Glass Co Ltd | Fluorinated adamantane derivatives |
GB0514203D0 (en) * | 2005-07-11 | 2005-08-17 | Novartis Ag | Organic compounds |
US9150507B2 (en) | 2006-04-28 | 2015-10-06 | Shionogi & Co., Ltd. | Amine derivative having NPY Y5 receptor antagonistic activity |
JP5187901B2 (ja) | 2006-08-30 | 2013-04-24 | 塩野義製薬株式会社 | ヒドラジンアミド誘導体 |
WO2008026564A1 (fr) | 2006-08-30 | 2008-03-06 | Shionogi & Co., Ltd. | Dérivés d'urée |
JP5019396B2 (ja) | 2006-10-18 | 2012-09-05 | 塩野義製薬株式会社 | 糖代謝改善剤 |
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