NO20021689D0 - 5-rings heterosykliske derivater, fremstilling derav og anvendelse som medikamenter - Google Patents
5-rings heterosykliske derivater, fremstilling derav og anvendelse som medikamenterInfo
- Publication number
- NO20021689D0 NO20021689D0 NO20021689A NO20021689A NO20021689D0 NO 20021689 D0 NO20021689 D0 NO 20021689D0 NO 20021689 A NO20021689 A NO 20021689A NO 20021689 A NO20021689 A NO 20021689A NO 20021689 D0 NO20021689 D0 NO 20021689D0
- Authority
- NO
- Norway
- Prior art keywords
- drugs
- preparation
- heterocyclic derivatives
- ring heterocyclic
- ring
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9912643A FR2799461B1 (fr) | 1999-10-11 | 1999-10-11 | Derives d'heterocycles a 5 chainons, leur preparation et leur application a titre de medicaments |
| FR0010151A FR2812546B1 (fr) | 2000-08-01 | 2000-08-01 | Derives d'heterocycles a 5 chainons, leur preparation et leur application a titre de medicaments |
| FR0011169 | 2000-09-01 | ||
| PCT/FR2000/002805 WO2001026656A2 (fr) | 1999-10-11 | 2000-10-10 | Derives d'heterocycles a 5 chainons et leur application comme inhibiteurs de monoamine oxydase |
Publications (3)
| Publication Number | Publication Date |
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| NO20021689D0 true NO20021689D0 (no) | 2002-04-10 |
| NO20021689L NO20021689L (no) | 2002-05-30 |
| NO331874B1 NO331874B1 (no) | 2012-04-23 |
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| NO20021689A NO331874B1 (no) | 1999-10-11 | 2002-04-10 | 4-[2(aminometyl)-1,3-tiazol-4-yl]-2,6-di(tert-butyl)fenol, anvendelse som medikamenter samt anvendelse for behandling av sykdom. |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US20070021390A1 (no) |
| EP (3) | EP1228760B1 (no) |
| JP (1) | JP4972263B2 (no) |
| KR (2) | KR20070068491A (no) |
| CN (1) | CN100488506C (no) |
| AR (1) | AR029006A1 (no) |
| AT (2) | ATE338547T1 (no) |
| AU (1) | AU783129B2 (no) |
| BR (1) | BR0014649A (no) |
| CA (1) | CA2388505C (no) |
| CY (1) | CY1106237T1 (no) |
| CZ (1) | CZ304331B6 (no) |
| DE (1) | DE60030574T2 (no) |
| DK (2) | DK1223933T3 (no) |
| ES (2) | ES2544856T3 (no) |
| HK (1) | HK1049957B (no) |
| HU (1) | HU228254B1 (no) |
| IL (3) | IL148896A0 (no) |
| MX (1) | MXPA02003665A (no) |
| MY (1) | MY145388A (no) |
| NO (1) | NO331874B1 (no) |
| NZ (2) | NZ533429A (no) |
| PL (1) | PL215580B1 (no) |
| PT (2) | PT1223933E (no) |
| RU (1) | RU2271355C2 (no) |
| TW (2) | TWI292316B (no) |
| WO (1) | WO2001026656A2 (no) |
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| TWI292316B (en) * | 1999-10-11 | 2008-01-11 | Sod Conseils Rech Applic | Pharmaceutical composition of thiazole derivatives intended to inhibit mao and/or lipidic peroxidation and/or to act as modulators of sodium channels and the use thereof |
| US7291641B2 (en) * | 1999-10-11 | 2007-11-06 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments |
| FR2818978B1 (fr) * | 2000-12-28 | 2003-02-28 | Sod Conseils Rech Applic | Modulateurs de canaux sodiques derives de 2-piperidylimidazoles |
| TWI248438B (en) * | 2001-04-10 | 2006-02-01 | Sod Conseils Rech Applic | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments |
| FR2825926A1 (fr) * | 2001-06-14 | 2002-12-20 | Sod Conseils Rech Applic | Derives d'imidazoles modulant les canaux sodiques |
| HU228783B1 (en) | 2001-07-26 | 2013-05-28 | Greenearth Cleaning | Dry cleaning apparatus and method capable of utilizing a siloxane solvent |
| CA2459125A1 (en) * | 2001-09-26 | 2003-04-03 | Theravance, Inc. | Substituted phenol compounds useful for anesthesia and sedation |
| US7022705B2 (en) | 2001-10-25 | 2006-04-04 | Astrazeneca Ab | Isoxazoline derivatives useful as antimicrobials |
| AU2002349705A1 (en) | 2001-12-03 | 2003-06-17 | Japan Tobacco Inc. | Azole compound and medicinal use thereof |
| FR2835254B1 (fr) * | 2002-01-25 | 2006-04-07 | Sod Conseils Rech Applic | Derives de thiazoles dans le traitement de maladies neurologiques |
| FR2842808B1 (fr) * | 2002-07-25 | 2004-09-10 | Sod Conseils Rech Applic | Nouveaux derives d'arylimidazoles, leur preparation et leurs applications therapeutiques |
| AU2003264018A1 (en) * | 2002-08-09 | 2004-02-25 | Astrazeneca Ab | Compounds having an activity at metabotropic glutamate receptors |
| KR20050033070A (ko) | 2002-08-09 | 2005-04-08 | 아스트라제네카 에이비이 | 메타보트로픽 글루타메이트 수용체-5의 조절제로서[1,2,4]옥사디아졸 |
| AU2003268064A1 (en) * | 2002-08-09 | 2004-02-25 | Astrazeneca Ab | Oxadiazoles as modulators of metabotropic glutamate receptor-5 |
| WO2004071448A2 (en) * | 2003-02-12 | 2004-08-26 | Transtech Pharma Inc. | Substituted azole derivatives as inhibitors of protein tyrosine phosphatases |
| WO2004089918A1 (ja) * | 2003-04-09 | 2004-10-21 | Japan Tobacco Inc. | 複素芳香5員環化合物及びその医薬用途 |
| US7732162B2 (en) | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
| US7446127B2 (en) * | 2003-08-27 | 2008-11-04 | Sk Holdings Co, Ltd. | Chroman carboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| EP1533295A1 (en) * | 2003-11-24 | 2005-05-25 | Newron Pharmaceuticals S.p.A. | Cyclopentyl Derivatives |
| ES2530579T3 (es) * | 2003-12-23 | 2015-03-03 | Abraxis Bioscience Llc | Análogos de propofol, procedimiento para su preparación, y procedimientos de uso |
| US7453002B2 (en) | 2004-06-15 | 2008-11-18 | Bristol-Myers Squibb Company | Five-membered heterocycles useful as serine protease inhibitors |
| JP4836280B2 (ja) | 2004-06-18 | 2011-12-14 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 癌を治療するためのキネシンスピンドルタンパク質(ksp)阻害剤としてのn−(1−(1−ベンジル−4−フェニル−1h−イミダゾール−2−イル)−2,2−ジメチルプロピル)ベンズアミド誘導体および関連化合物 |
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| DE602006021535D1 (de) * | 2005-01-19 | 2011-06-09 | Merck Sharp & Dohme | Als inhibitoren von beta-secretase aktive tertiäre carbinamine mit substituierten heterocyclen zur behandlung der alzheimer-krankheit |
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| JP5379692B2 (ja) | 2006-11-09 | 2013-12-25 | プロビオドルグ エージー | 潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての3−ヒドロキシ−1,5−ジヒドロ−ピロール−2−オン誘導体 |
| EP2091948B1 (en) | 2006-11-30 | 2012-04-18 | Probiodrug AG | Novel inhibitors of glutaminyl cyclase |
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| GB0822486D0 (en) * | 2008-12-10 | 2009-01-14 | Univ Liverpool | Compounds for use in the treatment of pain |
| KR101220182B1 (ko) * | 2009-02-25 | 2013-01-11 | 에스케이바이오팜 주식회사 | 치환된 아졸 유도체 화합물, 이를 포함하는 약제학적 조성물 및 이를 이용한 파킨슨씨 병 치료방법 |
| BR112012008346B1 (pt) | 2009-09-11 | 2021-12-21 | Vivoryon Therapeutics N.V. | Derivados heterocíclicos, seu processo de preparação, e composição farmacêutica |
| WO2011107530A2 (en) | 2010-03-03 | 2011-09-09 | Probiodrug Ag | Novel inhibitors |
| DK2545047T3 (da) | 2010-03-10 | 2014-07-28 | Probiodrug Ag | Heterocycliske inhibitorer af glutaminylcyclase (QC, EC 2.3.2.5) |
| EP2560953B1 (en) | 2010-04-21 | 2016-01-06 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
| WO2012123563A1 (en) | 2011-03-16 | 2012-09-20 | Probiodrug Ag | Benz imidazole derivatives as inhibitors of glutaminyl cyclase |
| RU2506082C2 (ru) * | 2011-05-24 | 2014-02-10 | Государственное учебно-научное учреждение Химический факультет Московского государственного университета им. М.В. Ломоносова | Антигипотоническое средство |
| UA109220C2 (uk) * | 2011-10-26 | 2015-07-27 | Пфайзер Лімітед | Похідні (4-фенілімідазол-2-іл)етиламіну як модулятори натрієвих каналів |
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| US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| HRP20251187T1 (hr) | 2013-07-12 | 2025-11-21 | Areteia Therapeutics, Inc. | Liječenje povišenih razina eozinofila i/ili bazofila |
| US9763918B2 (en) | 2013-08-13 | 2017-09-19 | Knopp Biosciences Llc | Compositions and methods for treating chronic urticaria |
| US9642840B2 (en) | 2013-08-13 | 2017-05-09 | Knopp Biosciences, Llc | Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders |
| PL3461819T3 (pl) | 2017-09-29 | 2020-11-30 | Probiodrug Ag | Inhibitory cyklazy glutaminylowej |
| US12030875B2 (en) | 2018-09-07 | 2024-07-09 | PIC Therapeutics, Inc. | EIF4E inhibitors and uses thereof |
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| WO2022015782A1 (en) * | 2020-07-15 | 2022-01-20 | Board Of Trustees Of Michigan State University | Compositions and related methods for closed-loop recycling of polyesters |
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- 2000-10-09 TW TW093132951A patent/TWI292316B/zh not_active IP Right Cessation
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- 2000-10-10 ES ES05076749.0T patent/ES2544856T3/es not_active Expired - Lifetime
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- 2000-10-10 PT PT00967988T patent/PT1223933E/pt unknown
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- 2000-10-10 PL PL355147A patent/PL215580B1/pl not_active IP Right Cessation
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- 2000-10-10 CZ CZ2002-1292A patent/CZ304331B6/cs not_active IP Right Cessation
- 2000-10-10 RU RU2002112227/15A patent/RU2271355C2/ru not_active IP Right Cessation
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- 2000-10-10 EP EP02076763A patent/EP1228760B1/fr not_active Expired - Lifetime
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