NL8702855A - Nieuwe prostacyclinen. - Google Patents

Nieuwe prostacyclinen. Download PDF

Info

Publication number
NL8702855A
NL8702855A NL8702855A NL8702855A NL8702855A NL 8702855 A NL8702855 A NL 8702855A NL 8702855 A NL8702855 A NL 8702855A NL 8702855 A NL8702855 A NL 8702855A NL 8702855 A NL8702855 A NL 8702855A
Authority
NL
Netherlands
Prior art keywords
compounds according
hydrogen
compounds
methyl
formula
Prior art date
Application number
NL8702855A
Other languages
English (en)
Dutch (nl)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NL8702855A publication Critical patent/NL8702855A/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
NL8702855A 1986-12-01 1987-11-27 Nieuwe prostacyclinen. NL8702855A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93652286A 1986-12-01 1986-12-01
US93652286 1986-12-01

Publications (1)

Publication Number Publication Date
NL8702855A true NL8702855A (nl) 1988-07-01

Family

ID=25468757

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8702855A NL8702855A (nl) 1986-12-01 1987-11-27 Nieuwe prostacyclinen.

Country Status (14)

Country Link
JP (1) JPS63145275A (ja)
AT (1) AT391697B (ja)
AU (1) AU597128B2 (ja)
BE (1) BE1001271A5 (ja)
CH (1) CH674363A5 (ja)
DE (1) DE3740595A1 (ja)
DK (1) DK627787A (ja)
FR (1) FR2607501A1 (ja)
GB (1) GB2198130B (ja)
IT (1) IT1223390B (ja)
NL (1) NL8702855A (ja)
NZ (1) NZ222723A (ja)
SE (1) SE8704770L (ja)
ZA (1) ZA878947B (ja)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4565827A (en) * 1980-10-27 1986-01-21 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Substituted PGI2 -derivatives and pharmaceutical compositions containing them
US4472428A (en) * 1980-12-09 1984-09-18 Teijin Limited Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore
US4558142A (en) * 1981-03-11 1985-12-10 Hoffmann-La Roche Inc. 7-Fluoro-prostacyclin analogs
CH648556A5 (de) * 1981-03-11 1985-03-29 Hoffmann La Roche Fluorprostacycline.
JPS5867682A (ja) * 1981-10-16 1983-04-22 Teijin Ltd フルオロpgi↓2類の製法
JPS58150583A (ja) * 1982-03-04 1983-09-07 Teijin Ltd 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
JPS59227888A (ja) * 1983-06-10 1984-12-21 Asahi Glass Co Ltd 7−フルオロプロスタグランジン類の製造方法
US4634782A (en) * 1985-06-24 1987-01-06 Hoffmann-La Roche Inc. 7-fluoro-dihydro PGI compounds

Also Published As

Publication number Publication date
DE3740595A1 (de) 1988-06-16
ATA313887A (de) 1990-05-15
JPS63145275A (ja) 1988-06-17
AU8190787A (en) 1988-06-02
BE1001271A5 (fr) 1989-09-12
SE8704770L (sv) 1988-06-02
ZA878947B (en) 1988-06-01
GB8727991D0 (en) 1988-01-06
AU597128B2 (en) 1990-05-24
SE8704770D0 (sv) 1987-11-30
GB2198130A (en) 1988-06-08
DK627787D0 (da) 1987-11-30
IT8722814A0 (it) 1987-11-30
FR2607501A1 (fr) 1988-06-03
NZ222723A (en) 1990-11-27
IT1223390B (it) 1990-09-19
DK627787A (da) 1988-06-02
CH674363A5 (ja) 1990-05-31
GB2198130B (en) 1990-08-08
AT391697B (de) 1990-11-12

Similar Documents

Publication Publication Date Title
PL118567B1 (en) Process for preparing novel esters of 4-halogen-3-ketoandrosteno-4-carbo-17 betha-thiolic acidosteno-4-karbotiolovojj-17 kisloty
NL8601206A (nl) Di- of trieenvetzuuresters van erytromycine a, werkwijze voor de bereiding ervan alsmede farmaceutische en cosmetische preparaten, die dergelijke esters bevatten.
PT100671B (pt) Sal de l-ascorbato de 16-descarboxi-16-hidroxi-metilanfotericina b e processo para a sua preparacao
JPH01193290A (ja) マクロライドおよびリンコサミド抗生物質の多環式芳香族エステル、その製法、並びに医薬・化粧品
JPH01193293A (ja) マクロライドのレチノイン酸エステル、その製造方法及びこれを含有する化粧料組成物
KR100266834B1 (ko) 프로스타글란딘 유도체
CH658189A5 (fr) Composition anti-acneique contenant en tant que compose actif un derive d'isothiazolo-(5,4b) pyridine one-3.
EP0656889B1 (de) 9-chlor-prostaglandin-ester und -amide und ihre verwendung für die herstellung von arzneimitteln
JPS61178973A (ja) 新規レチン酸誘導体とその製造方法およびこれを含有する医薬組成物ならびに化粧品組成物
NL8702855A (nl) Nieuwe prostacyclinen.
DE4229050A1 (de) Neue 9-Chlor-Prostaglandin-Ester und -amide
US4269853A (en) Composition and method for treating skin mast cells and/or delayed cellular hypersensitivity reactions
FR2550091A1 (fr) Composition pharmaceutique ou veterinaire destinee a combattre des troubles ischemiques cardiaques contenant un derive du benzofuranne
FR2528846A1 (fr) Nouveau derive de la pyrazolo (1,5-a) pyridine, sa preparation et les compositions pharmaceutiques qui le contiennent
AU651619B2 (en) Topical treatment and composition
CA1116082A (en) Pharmaceutical compositions and method of use
BE864450R (fr) Compositions pharmaceutiques a base d'anthocyanidine, leur preparation et leur utilisation
US5004729A (en) Aromatic esters of macrolidic and lincosamidic antibiotics and pharmaceutical and cosmetic compositions containing them
EP0082385B1 (de) 1-(3-Nitrophenyl)pyrido(2.3-d)pyrimidin-2.4(1H, 3H)-dione und 1-(3-Nitrophenyl)chinazolin-2.4(1H, 3H)-dione als cutane Arzneimittel
DE4229048A1 (de) Ester von 9-Chlor-Prostaglandinen, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
JPH01193289A (ja) マクロライドおよびリンコサミド抗生物質の二芳香族エステル、その製法、並びに医薬・化粧品
FR2555450A1 (fr) Composition anti-acneique contenant en tant que compose actif un derive d'isothiazolo-(5,4b) pyridine one-3
NL7908189A (nl) Nieuwe perhydrothiazine-1.3-derivaten, de bereiding ervan, alsmede geneesmiddelen die de nieuwe derivaten bevatten.
DE2246709A1 (de) Neue aminoester
JPS6160047B2 (ja)

Legal Events

Date Code Title Description
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: HOFFMANN-LA ROCHE AG. F. -

BV The patent application has lapsed