AU597128B2 - Novel prostacyclines - Google Patents

Novel prostacyclines

Info

Publication number
AU597128B2
AU597128B2 AU81907/87A AU8190787A AU597128B2 AU 597128 B2 AU597128 B2 AU 597128B2 AU 81907/87 A AU81907/87 A AU 81907/87A AU 8190787 A AU8190787 A AU 8190787A AU 597128 B2 AU597128 B2 AU 597128B2
Authority
AU
Australia
Prior art keywords
prostacyclines
novel
novel prostacyclines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU81907/87A
Other languages
English (en)
Other versions
AU8190787A (en
Inventor
George William Holland
Hans Maag
Perry Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU8190787A publication Critical patent/AU8190787A/en
Application granted granted Critical
Publication of AU597128B2 publication Critical patent/AU597128B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
AU81907/87A 1986-12-01 1987-11-30 Novel prostacyclines Ceased AU597128B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93652286A 1986-12-01 1986-12-01
US936522 1986-12-01

Publications (2)

Publication Number Publication Date
AU8190787A AU8190787A (en) 1988-06-02
AU597128B2 true AU597128B2 (en) 1990-05-24

Family

ID=25468757

Family Applications (1)

Application Number Title Priority Date Filing Date
AU81907/87A Ceased AU597128B2 (en) 1986-12-01 1987-11-30 Novel prostacyclines

Country Status (14)

Country Link
JP (1) JPS63145275A (ja)
AT (1) AT391697B (ja)
AU (1) AU597128B2 (ja)
BE (1) BE1001271A5 (ja)
CH (1) CH674363A5 (ja)
DE (1) DE3740595A1 (ja)
DK (1) DK627787A (ja)
FR (1) FR2607501A1 (ja)
GB (1) GB2198130B (ja)
IT (1) IT1223390B (ja)
NL (1) NL8702855A (ja)
NZ (1) NZ222723A (ja)
SE (1) SE8704770L (ja)
ZA (1) ZA878947B (ja)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58150583A (ja) * 1982-03-04 1983-09-07 Teijin Ltd 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
AU5920486A (en) * 1985-06-24 1987-01-08 F. Hoffmann-La Roche Ag 6,9-epoxy-7-fluoro-11-hydroxy-prost-5-en-1-oic acid derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4565827A (en) * 1980-10-27 1986-01-21 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Substituted PGI2 -derivatives and pharmaceutical compositions containing them
US4472428A (en) * 1980-12-09 1984-09-18 Teijin Limited Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore
US4558142A (en) * 1981-03-11 1985-12-10 Hoffmann-La Roche Inc. 7-Fluoro-prostacyclin analogs
CH648556A5 (de) * 1981-03-11 1985-03-29 Hoffmann La Roche Fluorprostacycline.
JPS5867682A (ja) * 1981-10-16 1983-04-22 Teijin Ltd フルオロｐｇｉ↓２類の製法
JPS59227888A (ja) * 1983-06-10 1984-12-21 Asahi Glass Co Ltd ７−フルオロプロスタグランジン類の製造方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58150583A (ja) * 1982-03-04 1983-09-07 Teijin Ltd 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
AU5920486A (en) * 1985-06-24 1987-01-08 F. Hoffmann-La Roche Ag 6,9-epoxy-7-fluoro-11-hydroxy-prost-5-en-1-oic acid derivatives

Also Published As

Publication number Publication date
DE3740595A1 (de) 1988-06-16
ATA313887A (de) 1990-05-15
JPS63145275A (ja) 1988-06-17
AU8190787A (en) 1988-06-02
BE1001271A5 (fr) 1989-09-12
SE8704770L (sv) 1988-06-02
ZA878947B (en) 1988-06-01
GB8727991D0 (en) 1988-01-06
SE8704770D0 (sv) 1987-11-30
NL8702855A (nl) 1988-07-01
GB2198130A (en) 1988-06-08
DK627787D0 (da) 1987-11-30
IT8722814A0 (it) 1987-11-30
FR2607501A1 (fr) 1988-06-03
NZ222723A (en) 1990-11-27
IT1223390B (it) 1990-09-19
DK627787A (da) 1988-06-02
CH674363A5 (ja) 1990-05-31
GB2198130B (en) 1990-08-08
AT391697B (de) 1990-11-12

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