NZ222723A - Fluoro-prostacyclines and pharmaceutical compositions - Google Patents

Fluoro-prostacyclines and pharmaceutical compositions

Info

Publication number
NZ222723A
NZ222723A NZ222723A NZ22272387A NZ222723A NZ 222723 A NZ222723 A NZ 222723A NZ 222723 A NZ222723 A NZ 222723A NZ 22272387 A NZ22272387 A NZ 22272387A NZ 222723 A NZ222723 A NZ 222723A
Authority
NZ
New Zealand
Prior art keywords
compounds
formula
pharmaceutically acceptable
compound
pharmaceutical preparations
Prior art date
Application number
NZ222723A
Other languages
English (en)
Inventor
George William Holland
Hans Maag
Perry Rosen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NZ222723A publication Critical patent/NZ222723A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
NZ222723A 1986-12-01 1987-11-27 Fluoro-prostacyclines and pharmaceutical compositions NZ222723A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93652286A 1986-12-01 1986-12-01

Publications (1)

Publication Number Publication Date
NZ222723A true NZ222723A (en) 1990-11-27

Family

ID=25468757

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ222723A NZ222723A (en) 1986-12-01 1987-11-27 Fluoro-prostacyclines and pharmaceutical compositions

Country Status (14)

Country Link
JP (1) JPS63145275A (ja)
AT (1) AT391697B (ja)
AU (1) AU597128B2 (ja)
BE (1) BE1001271A5 (ja)
CH (1) CH674363A5 (ja)
DE (1) DE3740595A1 (ja)
DK (1) DK627787A (ja)
FR (1) FR2607501A1 (ja)
GB (1) GB2198130B (ja)
IT (1) IT1223390B (ja)
NL (1) NL8702855A (ja)
NZ (1) NZ222723A (ja)
SE (1) SE8704770L (ja)
ZA (1) ZA878947B (ja)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4565827A (en) * 1980-10-27 1986-01-21 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Substituted PGI2 -derivatives and pharmaceutical compositions containing them
US4472428A (en) * 1980-12-09 1984-09-18 Teijin Limited Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore
US4558142A (en) * 1981-03-11 1985-12-10 Hoffmann-La Roche Inc. 7-Fluoro-prostacyclin analogs
CH648556A5 (de) * 1981-03-11 1985-03-29 Hoffmann La Roche Fluorprostacycline.
JPS5867682A (ja) * 1981-10-16 1983-04-22 Teijin Ltd フルオロpgi↓2類の製法
JPS58150583A (ja) * 1982-03-04 1983-09-07 Teijin Ltd 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
JPS59227888A (ja) * 1983-06-10 1984-12-21 Asahi Glass Co Ltd 7−フルオロプロスタグランジン類の製造方法
US4634782A (en) * 1985-06-24 1987-01-06 Hoffmann-La Roche Inc. 7-fluoro-dihydro PGI compounds

Also Published As

Publication number Publication date
DE3740595A1 (de) 1988-06-16
ATA313887A (de) 1990-05-15
JPS63145275A (ja) 1988-06-17
AU8190787A (en) 1988-06-02
BE1001271A5 (fr) 1989-09-12
SE8704770L (sv) 1988-06-02
ZA878947B (en) 1988-06-01
GB8727991D0 (en) 1988-01-06
AU597128B2 (en) 1990-05-24
SE8704770D0 (sv) 1987-11-30
NL8702855A (nl) 1988-07-01
GB2198130A (en) 1988-06-08
DK627787D0 (da) 1987-11-30
IT8722814A0 (it) 1987-11-30
FR2607501A1 (fr) 1988-06-03
IT1223390B (it) 1990-09-19
DK627787A (da) 1988-06-02
CH674363A5 (ja) 1990-05-31
GB2198130B (en) 1990-08-08
AT391697B (de) 1990-11-12

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