BE1001271A5 - Nouvelles prostacyclines. - Google Patents

Nouvelles prostacyclines. Download PDF

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Publication number
BE1001271A5
BE1001271A5 BE8701358A BE8701358A BE1001271A5 BE 1001271 A5 BE1001271 A5 BE 1001271A5 BE 8701358 A BE8701358 A BE 8701358A BE 8701358 A BE8701358 A BE 8701358A BE 1001271 A5 BE1001271 A5 BE 1001271A5
Authority
BE
Belgium
Prior art keywords
sep
compounds according
formula
compounds
acid
Prior art date
Application number
BE8701358A
Other languages
English (en)
French (fr)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of BE1001271A5 publication Critical patent/BE1001271A5/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
BE8701358A 1986-12-01 1987-11-30 Nouvelles prostacyclines. BE1001271A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93652286A 1986-12-01 1986-12-01

Publications (1)

Publication Number Publication Date
BE1001271A5 true BE1001271A5 (fr) 1989-09-12

Family

ID=25468757

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8701358A BE1001271A5 (fr) 1986-12-01 1987-11-30 Nouvelles prostacyclines.

Country Status (14)

Country Link
JP (1) JPS63145275A (ja)
AT (1) AT391697B (ja)
AU (1) AU597128B2 (ja)
BE (1) BE1001271A5 (ja)
CH (1) CH674363A5 (ja)
DE (1) DE3740595A1 (ja)
DK (1) DK627787A (ja)
FR (1) FR2607501A1 (ja)
GB (1) GB2198130B (ja)
IT (1) IT1223390B (ja)
NL (1) NL8702855A (ja)
NZ (1) NZ222723A (ja)
SE (1) SE8704770L (ja)
ZA (1) ZA878947B (ja)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2088856A (en) * 1980-10-27 1982-06-16 Chinoin Gyogyszer Es Vegyeszet 7-substituted pg12-derivatives their preparation and pharmaceutical compositions containing them
EP0054795A2 (en) * 1980-12-09 1982-06-30 Teijin Limited Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof
JPS5867682A (ja) * 1981-10-16 1983-04-22 Teijin Ltd フルオロｐｇｉ↓２類の製法
JPS58150583A (ja) * 1982-03-04 1983-09-07 Teijin Ltd 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
EP0148953A1 (en) * 1983-06-10 1985-07-24 Asahi Glass Company Ltd. 7-fluoroprostaglandins and process for their preparation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558142A (en) * 1981-03-11 1985-12-10 Hoffmann-La Roche Inc. 7-Fluoro-prostacyclin analogs
CH648556A5 (de) * 1981-03-11 1985-03-29 Hoffmann La Roche Fluorprostacycline.
US4634782A (en) * 1985-06-24 1987-01-06 Hoffmann-La Roche Inc. 7-fluoro-dihydro PGI compounds

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2088856A (en) * 1980-10-27 1982-06-16 Chinoin Gyogyszer Es Vegyeszet 7-substituted pg12-derivatives their preparation and pharmaceutical compositions containing them
EP0054795A2 (en) * 1980-12-09 1982-06-30 Teijin Limited Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof
JPS5867682A (ja) * 1981-10-16 1983-04-22 Teijin Ltd フルオロｐｇｉ↓２類の製法
JPS58150583A (ja) * 1982-03-04 1983-09-07 Teijin Ltd 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
EP0148953A1 (en) * 1983-06-10 1985-07-24 Asahi Glass Company Ltd. 7-fluoroprostaglandins and process for their preparation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 100, no. 11, 12 mars 1984, page 525, résumé no. 85494v, Columbus, Ohio, US; & JP-A-58 150 583 (TEIJIN LTD) 07-09-1983 *
CHEMICAL ABSTRACTS, vol. 99, no. 11, 12 septembre 1983, page 543, résumé no. 87908t, Columbus, Ohio, US; & JP-A-58 67 682 (TEIJIN LTD) 22-04-1983 *
TETRAHEDRON, vol. 39, no. 22, 1983, pages 3807-3819, Pergamon Press Ltd, Oxford, GB; K. BANNAI et al.: "Synthesis of chemically stable prostacyclin analogs" *

Also Published As

Publication number Publication date
DE3740595A1 (de) 1988-06-16
ATA313887A (de) 1990-05-15
JPS63145275A (ja) 1988-06-17
AU8190787A (en) 1988-06-02
SE8704770L (sv) 1988-06-02
ZA878947B (en) 1988-06-01
GB8727991D0 (en) 1988-01-06
AU597128B2 (en) 1990-05-24
SE8704770D0 (sv) 1987-11-30
NL8702855A (nl) 1988-07-01
GB2198130A (en) 1988-06-08
DK627787D0 (da) 1987-11-30
IT8722814A0 (it) 1987-11-30
FR2607501A1 (fr) 1988-06-03
NZ222723A (en) 1990-11-27
IT1223390B (it) 1990-09-19
DK627787A (da) 1988-06-02
CH674363A5 (ja) 1990-05-31
GB2198130B (en) 1990-08-08
AT391697B (de) 1990-11-12

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE A.G.

Effective date: 19911130