AU8190787A - Novel prostacyclines - Google Patents

Novel prostacyclines

Info

Publication number
AU8190787A
AU8190787A AU81907/87A AU8190787A AU8190787A AU 8190787 A AU8190787 A AU 8190787A AU 81907/87 A AU81907/87 A AU 81907/87A AU 8190787 A AU8190787 A AU 8190787A AU 8190787 A AU8190787 A AU 8190787A
Authority
AU
Australia
Prior art keywords
prostacyclines
novel
novel prostacyclines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU81907/87A
Other versions
AU597128B2 (en
Inventor
George William Holland
Hans Maag
Perry Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU8190787A publication Critical patent/AU8190787A/en
Application granted granted Critical
Publication of AU597128B2 publication Critical patent/AU597128B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
AU81907/87A 1986-12-01 1987-11-30 Novel prostacyclines Ceased AU597128B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93652286A 1986-12-01 1986-12-01
US936522 1986-12-01

Publications (2)

Publication Number Publication Date
AU8190787A true AU8190787A (en) 1988-06-02
AU597128B2 AU597128B2 (en) 1990-05-24

Family

ID=25468757

Family Applications (1)

Application Number Title Priority Date Filing Date
AU81907/87A Ceased AU597128B2 (en) 1986-12-01 1987-11-30 Novel prostacyclines

Country Status (14)

Country Link
JP (1) JPS63145275A (en)
AT (1) AT391697B (en)
AU (1) AU597128B2 (en)
BE (1) BE1001271A5 (en)
CH (1) CH674363A5 (en)
DE (1) DE3740595A1 (en)
DK (1) DK627787A (en)
FR (1) FR2607501A1 (en)
GB (1) GB2198130B (en)
IT (1) IT1223390B (en)
NL (1) NL8702855A (en)
NZ (1) NZ222723A (en)
SE (1) SE8704770L (en)
ZA (1) ZA878947B (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2088856B (en) * 1980-10-27 1984-06-27 Chinoin Gyogyszer Es Vegyeszet 7-substituted pg12-derivatives their preparation and pharmaceutical compositions containing them
EP0054795B1 (en) * 1980-12-09 1987-07-15 Teijin Limited Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof
US4558142A (en) * 1981-03-11 1985-12-10 Hoffmann-La Roche Inc. 7-Fluoro-prostacyclin analogs
CH648556A5 (en) * 1981-03-11 1985-03-29 Hoffmann La Roche FLUORPROSTACYCLINE.
JPS5867682A (en) * 1981-10-16 1983-04-22 Teijin Ltd Preparation of fluoro-pgi2
JPS58150583A (en) * 1982-03-04 1983-09-07 Teijin Ltd Novel halogenated prostacyclins, their preparations, and pharmaceutical compositions comprising them as active ingredients
JPS59227888A (en) * 1983-06-10 1984-12-21 Asahi Glass Co Ltd Production of 7-fluoroprostaglandin
US4634782A (en) * 1985-06-24 1987-01-06 Hoffmann-La Roche Inc. 7-fluoro-dihydro PGI compounds

Also Published As

Publication number Publication date
SE8704770D0 (en) 1987-11-30
GB2198130A (en) 1988-06-08
ATA313887A (en) 1990-05-15
BE1001271A5 (en) 1989-09-12
SE8704770L (en) 1988-06-02
CH674363A5 (en) 1990-05-31
GB8727991D0 (en) 1988-01-06
DK627787A (en) 1988-06-02
JPS63145275A (en) 1988-06-17
NL8702855A (en) 1988-07-01
DE3740595A1 (en) 1988-06-16
NZ222723A (en) 1990-11-27
FR2607501A1 (en) 1988-06-03
ZA878947B (en) 1988-06-01
AT391697B (en) 1990-11-12
IT1223390B (en) 1990-09-19
AU597128B2 (en) 1990-05-24
GB2198130B (en) 1990-08-08
IT8722814A0 (en) 1987-11-30
DK627787D0 (en) 1987-11-30

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