GB2088856B - 7-substituted pg12-derivatives their preparation and pharmaceutical compositions containing them - Google Patents

7-substituted pg12-derivatives their preparation and pharmaceutical compositions containing them

Info

Publication number
GB2088856B
GB2088856B GB8132351A GB8132351A GB2088856B GB 2088856 B GB2088856 B GB 2088856B GB 8132351 A GB8132351 A GB 8132351A GB 8132351 A GB8132351 A GB 8132351A GB 2088856 B GB2088856 B GB 2088856B
Authority
GB
United Kingdom
Prior art keywords
derivatives
substituted
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8132351A
Other versions
GB2088856A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VEGYESZETI TERMEKEK GYAR RT
Chinoin Private Co Ltd
Original Assignee
VEGYESZETI TERMEKEK GYAR RT
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU258980A external-priority patent/HU184341B/en
Priority claimed from HU258780A external-priority patent/HU184917B/en
Priority claimed from HU258880A external-priority patent/HU184918B/en
Application filed by VEGYESZETI TERMEKEK GYAR RT, Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical VEGYESZETI TERMEKEK GYAR RT
Publication of GB2088856A publication Critical patent/GB2088856A/en
Application granted granted Critical
Publication of GB2088856B publication Critical patent/GB2088856B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB8132351A 1980-10-27 1981-10-27 7-substituted pg12-derivatives their preparation and pharmaceutical compositions containing them Expired GB2088856B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU258980A HU184341B (en) 1980-10-27 1980-10-27 Process for preparing 7-substituted pgi down 1 derivatives
HU258780A HU184917B (en) 1980-10-27 1980-10-27 Process for preparing 7-substituted pgi down 2 derivatives
HU258880A HU184918B (en) 1980-10-27 1980-10-27 Process for producing simultaneously pgf-2 down alpha derivatives substituted at the 4 or 7 position

Publications (2)

Publication Number Publication Date
GB2088856A GB2088856A (en) 1982-06-16
GB2088856B true GB2088856B (en) 1984-06-27

Family

ID=27269997

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8132351A Expired GB2088856B (en) 1980-10-27 1981-10-27 7-substituted pg12-derivatives their preparation and pharmaceutical compositions containing them

Country Status (2)

Country Link
US (1) US4565827A (en)
GB (1) GB2088856B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558142A (en) * 1981-03-11 1985-12-10 Hoffmann-La Roche Inc. 7-Fluoro-prostacyclin analogs
US4650883A (en) * 1981-03-11 1987-03-17 Hoffmann-La Roche Inc. Hexahydro-3-fluoro-4-octenyl-2H-cyclopenta[β]furan-2-ones
CH648556A5 (en) * 1981-03-11 1985-03-29 Hoffmann La Roche FLUORPROSTACYCLINE.
DE3322893A1 (en) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen NEW PROSTACYCLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
US4634782A (en) * 1985-06-24 1987-01-06 Hoffmann-La Roche Inc. 7-fluoro-dihydro PGI compounds
US4681962A (en) * 1985-06-24 1987-07-21 Hoffmann-La Roche Inc. Novel 7-fluoro-dihydro PGI compounds
US4680415A (en) * 1985-06-24 1987-07-14 Hoffmann-La Roche Inc. Intermediates for 7-fluoro dihydro PGI compounds
US4808734A (en) * 1986-12-01 1989-02-28 Hoffmann-La Roche Inc. 16-cycloalkyl-7-fluoro-prostacyclins
CH674363A5 (en) * 1986-12-01 1990-05-31 Hoffmann La Roche
DE69228235T2 (en) * 1991-10-25 1999-07-01 Toray Industries Use of an agent for the manufacture of a medicament for the treatment of liver disease
ES2116630T3 (en) * 1994-02-17 1998-07-16 Asahi Glass Co Ltd DIFLUORPROSTACICLINAS; INTERMEDIARY PRODUCTS AND PROCEDURES FOR ITS PREPARATION.
EP2343292B1 (en) * 2008-09-10 2014-08-06 Asahi Glass Company, Limited Novel prostaglandin i2 derivative

Also Published As

Publication number Publication date
US4565827A (en) 1986-01-21
GB2088856A (en) 1982-06-16

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee