ZA878947B - Novel prostracyclines - Google Patents

Novel prostracyclines

Info

Publication number
ZA878947B
ZA878947B ZA878947A ZA878947A ZA878947B ZA 878947 B ZA878947 B ZA 878947B ZA 878947 A ZA878947 A ZA 878947A ZA 878947 A ZA878947 A ZA 878947A ZA 878947 B ZA878947 B ZA 878947B
Authority
ZA
South Africa
Prior art keywords
prostracyclines
novel
novel prostracyclines
Prior art date
Application number
ZA878947A
Other languages
English (en)
Inventor
William Holland George
Maag Hans
Rosen Perry
Original Assignee
F. Hoffmann-La Roche & Co. Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche & Co. Aktiengesellschaft filed Critical F. Hoffmann-La Roche & Co. Aktiengesellschaft
Publication of ZA878947B publication Critical patent/ZA878947B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
ZA878947A 1986-12-01 1987-11-27 Novel prostracyclines ZA878947B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93652286A 1986-12-01 1986-12-01

Publications (1)

Publication Number Publication Date
ZA878947B true ZA878947B (en) 1988-06-01

Family

ID=25468757

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA878947A ZA878947B (en) 1986-12-01 1987-11-27 Novel prostracyclines

Country Status (14)

Country Link
JP (1) JPS63145275A (ja)
AT (1) AT391697B (ja)
AU (1) AU597128B2 (ja)
BE (1) BE1001271A5 (ja)
CH (1) CH674363A5 (ja)
DE (1) DE3740595A1 (ja)
DK (1) DK627787A (ja)
FR (1) FR2607501A1 (ja)
GB (1) GB2198130B (ja)
IT (1) IT1223390B (ja)
NL (1) NL8702855A (ja)
NZ (1) NZ222723A (ja)
SE (1) SE8704770L (ja)
ZA (1) ZA878947B (ja)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4565827A (en) * 1980-10-27 1986-01-21 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Substituted PGI2 -derivatives and pharmaceutical compositions containing them
US4472428A (en) * 1980-12-09 1984-09-18 Teijin Limited Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore
US4558142A (en) * 1981-03-11 1985-12-10 Hoffmann-La Roche Inc. 7-Fluoro-prostacyclin analogs
CH648556A5 (de) * 1981-03-11 1985-03-29 Hoffmann La Roche Fluorprostacycline.
JPS5867682A (ja) * 1981-10-16 1983-04-22 Teijin Ltd フルオロpgi↓2類の製法
JPS58150583A (ja) * 1982-03-04 1983-09-07 Teijin Ltd 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
JPS59227888A (ja) * 1983-06-10 1984-12-21 Asahi Glass Co Ltd 7−フルオロプロスタグランジン類の製造方法
US4634782A (en) * 1985-06-24 1987-01-06 Hoffmann-La Roche Inc. 7-fluoro-dihydro PGI compounds

Also Published As

Publication number Publication date
DE3740595A1 (de) 1988-06-16
ATA313887A (de) 1990-05-15
JPS63145275A (ja) 1988-06-17
AU8190787A (en) 1988-06-02
BE1001271A5 (fr) 1989-09-12
SE8704770L (sv) 1988-06-02
GB8727991D0 (en) 1988-01-06
AU597128B2 (en) 1990-05-24
SE8704770D0 (sv) 1987-11-30
NL8702855A (nl) 1988-07-01
GB2198130A (en) 1988-06-08
DK627787D0 (da) 1987-11-30
IT8722814A0 (it) 1987-11-30
FR2607501A1 (fr) 1988-06-03
NZ222723A (en) 1990-11-27
IT1223390B (it) 1990-09-19
DK627787A (da) 1988-06-02
CH674363A5 (ja) 1990-05-31
GB2198130B (en) 1990-08-08
AT391697B (de) 1990-11-12

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