NL8500241A - - 6-gesubstitueerde furo-(3,4-c)-pyridinederivaat. - Google Patents

- 6-gesubstitueerde furo-(3,4-c)-pyridinederivaat. Download PDF

Info

Publication number
NL8500241A
NL8500241A NL8500241A NL8500241A NL8500241A NL 8500241 A NL8500241 A NL 8500241A NL 8500241 A NL8500241 A NL 8500241A NL 8500241 A NL8500241 A NL 8500241A NL 8500241 A NL8500241 A NL 8500241A
Authority
NL
Netherlands
Prior art keywords
furo
pyridine
hydroxy
dihydro
benzyloxy
Prior art date
Application number
NL8500241A
Other languages
English (en)
Dutch (nl)
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of NL8500241A publication Critical patent/NL8500241A/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
NL8500241A 1984-02-02 1985-01-29 - 6-gesubstitueerde furo-(3,4-c)-pyridinederivaat. NL8500241A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848402740A GB8402740D0 (en) 1984-02-02 1984-02-02 Furo-(3 4-c)-pyridine derivatives
GB8402740 1984-02-02

Publications (1)

Publication Number Publication Date
NL8500241A true NL8500241A (nl) 1985-09-02

Family

ID=10555953

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8500241A NL8500241A (nl) 1984-02-02 1985-01-29 - 6-gesubstitueerde furo-(3,4-c)-pyridinederivaat.

Country Status (24)

Country Link
US (1) US4581362A (fr)
JP (1) JPS60181088A (fr)
AT (1) AT391700B (fr)
BE (1) BE901545A (fr)
CA (1) CA1300148C (fr)
CH (1) CH663023A5 (fr)
DE (1) DE3503435A1 (fr)
DK (1) DK158951C (fr)
DZ (1) DZ743A1 (fr)
ES (1) ES8607308A1 (fr)
FI (1) FI82051C (fr)
FR (2) FR2559062B1 (fr)
GB (1) GB8402740D0 (fr)
HK (1) HK92587A (fr)
IE (1) IE58229B1 (fr)
IT (1) IT1200587B (fr)
LU (1) LU85744A1 (fr)
MA (1) MA20342A1 (fr)
NL (1) NL8500241A (fr)
NO (1) NO160369C (fr)
OA (1) OA07947A (fr)
PT (1) PT79913B (fr)
SE (2) SE460903B (fr)
ZA (1) ZA85508B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427218D0 (en) * 1984-10-27 1984-12-05 Scras Pyridine derivatives
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
GB8907480D0 (en) * 1989-04-03 1989-05-17 Scaras Societe De Conseils De Separation of insomers of furo(3,4-c)pyridine derivatives
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
JPH054664A (ja) * 1991-06-21 1993-01-14 Yoozuri:Kk 運搬等用の包装体及び包装方法
PE20221914A1 (es) 2011-12-28 2022-12-23 Global Blood Therapeutics Inc Compuestos de benzaldehido sustituidos y metodos para su uso en incrementar la oxigenacion del tejido
EP2797597B1 (fr) 2011-12-28 2020-02-26 Global Blood Therapeutics, Inc. Composés d'aldéhydes hétéroaryles substitués et leurs procédés d'utilisation dans l'accroissement de l'oxygénation tissulaire
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
CN112500338A (zh) 2013-03-15 2021-03-16 全球血液疗法股份有限公司 化合物及其用于调节血红蛋白的用途
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10100043B2 (en) 2013-03-15 2018-10-16 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
AU2014237330A1 (en) 2013-03-15 2015-09-17 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
KR101971385B1 (ko) 2013-03-15 2019-04-22 글로벌 블러드 테라퓨틱스, 인크. 헤모글로빈 조정을 위한 화합물 및 이의 용도
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
AU2015214182B2 (en) 2014-02-07 2020-04-30 Global Blood Therapeutics, Inc. Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
MA43373A (fr) 2015-12-04 2018-10-10 Global Blood Therapeutics Inc Régimes posologiques pour 2-hydroxy-6-((2- (1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)méthoxy)benzaldéhyde
TWI663160B (zh) 2016-05-12 2019-06-21 全球血液治療公司 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
TW202332423A (zh) 2016-10-12 2023-08-16 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
WO2020072377A1 (fr) 2018-10-01 2020-04-09 Global Blood Therapeutics, Inc. Modulateurs de l'hémoglobine pour le traitement de la drépanocytose

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA786269B (en) * 1977-11-25 1979-10-31 Scras New pyridine derivative,its preparation and use
IN156817B (fr) * 1981-02-10 1985-11-09 Scras
GB8330517D0 (en) * 1983-11-16 1983-12-21 Scras 6-vinyl-furo-(3,4-c)pyridine derivatives
GB8330658D0 (en) * 1983-11-17 1983-12-29 Scras 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives

Also Published As

Publication number Publication date
OA07947A (fr) 1987-01-31
JPS60181088A (ja) 1985-09-14
ES8607308A1 (es) 1986-05-16
FI850275L (fi) 1985-08-03
CA1300148C (fr) 1992-05-05
FI850275A0 (fi) 1985-01-22
FI82051B (fi) 1990-09-28
NO160369C (no) 1989-04-12
DK158951C (da) 1990-12-31
SE460903B (sv) 1989-12-04
FR2559152A1 (fr) 1985-08-09
PT79913B (en) 1986-11-10
AT391700B (de) 1990-11-12
ZA85508B (en) 1985-11-27
DK158951B (da) 1990-08-06
IE58229B1 (en) 1993-08-11
FR2559062B1 (fr) 1987-05-22
DK45585D0 (da) 1985-02-01
FR2559152B1 (fr) 1987-05-22
CH663023A5 (fr) 1987-11-13
FR2559062A1 (fr) 1985-08-09
DE3503435A1 (de) 1985-08-08
SE8500460L (sv) 1985-08-03
JPH0240069B2 (fr) 1990-09-10
IT1200587B (it) 1989-01-27
BE901545A (fr) 1985-07-22
IT8519327A0 (it) 1985-02-01
PT79913A (en) 1985-03-01
NO160369B (no) 1989-01-02
FI82051C (fi) 1991-01-10
ES540080A0 (es) 1986-05-16
SE8500460D0 (sv) 1985-02-01
DK45585A (da) 1985-08-03
GB8402740D0 (en) 1984-03-07
MA20342A1 (fr) 1985-10-01
US4581362A (en) 1986-04-08
DE3503435C2 (fr) 1991-11-07
IE850241L (en) 1985-08-02
HK92587A (en) 1987-12-11
DZ743A1 (fr) 2004-09-13
NO850399L (no) 1985-08-05
ATA27585A (de) 1990-05-15
LU85744A1 (fr) 1985-07-24

Similar Documents

Publication Publication Date Title
NL8500241A (nl) - 6-gesubstitueerde furo-(3,4-c)-pyridinederivaat.
FI120094B (fi) Menetelmä terapeuttisesti käyttökelpoisten 1, 4- dihydrokinoksaliini-2,3-dionijohdannaisten valmistamiseksi
Rylands et al. Structure-activity relationship studies of antiplasmodial cyclometallated ruthenium (II), rhodium (III) and iridium (III) complexes of 2-phenylbenzimidazoles
NO337933B1 (no) Analoger av benzokinon-inneholdende ansamyciner samt fremgangsmåte for fremstilling derav og farmasøytisk sammensetning
Kolli et al. NaSH in the construction of thiophene ring fused with N-heterocycles: A rapid and inexpensive synthesis of novel small molecules as potential inducers of apoptosis
DE60216610T2 (de) Verwendung von kondensierten Pyrazolverbindungen für die Herstellung eines Arzneimittels zur Behandlung von Bluthochdruck
FI82248C (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla 6-fenetylaminoalkyl-furo-(3,4-c)-pyridinderivat.
NL8502324A (nl) Werkwijze voor het bereiden van 6-gesubstitueerde furo-(3,4-c)-pyridinederivaten.
Shcherbakov et al. Modification of polyfluoro-containing 3-(ethoxycarbonyl) flavones by biogenic amines and amino acids
Hynes et al. Synthesis of 5-chloro-5, 8-dideaza analogs of folic acid and aminopterin targeted for colon adenocarcinoma
IE58041B1 (en) 4-Chloro-furo-(3,4-c)-pyridine derivatives
US20080255080A1 (en) Hydroquinone Ansamycin Formulations
GB2153824A (en) Furo-(3,4-c)-pyridine derivatives
Deželić et al. Syntheses of Some 4-Hydroxycoumarins and Their Condensation Products with Aldehydes and Carboxylic Acids. The Anticoagulant Activity of Some 4-Hydroxycoumarin Derivatives
FI84723C (fi) Foerfarande foer framstaellning av terapeutiskt aktiva 2-(1,8-naftyridin-2-yl)-isoindolin-1-oner.
US9873699B1 (en) Anti-cancer agents
Galina et al. Synthesis of 3-Diazopyrrolidin-2-ones
NL8402891A (nl) Gecondenseerde as-triazinederivaten.
Disraeli Synthesis, biological activity and physicochemical properties evaluation of antiplasmodial pyrimido [1, 2-a] benzimidazoles
FI73216B (fi) Ett nytt foerfarande foer framstaellning av kondenserade pyrimidinderivat, deras optiskt aktiva isomerer och fysiologiskt godtagbara salter.
Barnard Synthesis and profiling of antimalarial side-chain modified pyrido [1, 2-a] benzimidazoles
NL9100941A (nl) Pyrrolopyridine-derivaten, werkwijze voor de bereiding daarvan en therapeutische preparaten die ze bevatten.
CS246337B1 (cs) Cyklické amidiny odvozené od 1-benzazepinu a jejich hydrochloridy
JPH06509800A (ja) 新規な3−(置換テトラゾリル)−4−オキソ−4H−ピリド[1,2−a]ピリミジン類、それらの塩、それらを含有する医薬組成物およびそれらの製法

Legal Events

Date Code Title Description
A1B A search report has been drawn up
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed
BV The patent application has lapsed