MY184130A - Peptidic growth hormone secretagogues analog compounds and preparations thereof - Google Patents

Peptidic growth hormone secretagogues analog compounds and preparations thereof

Info

Publication number
MY184130A
MY184130A MYPI20083178A MYPI20083178A MY184130A MY 184130 A MY184130 A MY 184130A MY PI20083178 A MYPI20083178 A MY PI20083178A MY PI20083178 A MYPI20083178 A MY PI20083178A MY 184130 A MY184130 A MY 184130A
Authority
MY
Malaysia
Prior art keywords
growth hormone
preparations
hormone secretagogues
analog compounds
peptidic
Prior art date
Application number
MYPI20083178A
Other languages
English (en)
Inventor
Masso Julio Raul Fernandez
Rodriguez Rebeca Martinez
Lasa Alexis Musacchio
Santiago Glay Chinea
Del Barco Herrera Diana Garcia
Acosta Jorge Amador Berlanga
Fernandez Rolando Eduardo Rodriguez
La Nuez Veulens Ania De
Garcia Mario Pablo Estrada
Acosta Osvaldo Reyes
Original Assignee
Ct Ingenieria Genetica Biotecnologia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40130780&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY184130(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ct Ingenieria Genetica Biotecnologia filed Critical Ct Ingenieria Genetica Biotecnologia
Publication of MY184130A publication Critical patent/MY184130A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fodder In General (AREA)
  • Peptides Or Proteins (AREA)
MYPI20083178A 2006-02-28 2007-02-28 Peptidic growth hormone secretagogues analog compounds and preparations thereof MY184130A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CU20060050A CU23558A1 (es) 2006-02-28 2006-02-28 Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento
PCT/CU2007/000007 WO2007098716A1 (es) 2006-02-28 2007-02-28 Compuestos analogos a los secretagogos peptidicos de la hormona de crecimiento y preparaciones que los contienen

Publications (1)

Publication Number Publication Date
MY184130A true MY184130A (en) 2021-03-19

Family

ID=40130780

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20083178A MY184130A (en) 2006-02-28 2007-02-28 Peptidic growth hormone secretagogues analog compounds and preparations thereof

Country Status (18)

Country Link
US (1) US8367620B2 (https=)
EP (1) EP1997827B1 (https=)
JP (1) JP5183496B2 (https=)
KR (1) KR101409277B1 (https=)
CN (1) CN101432294B (https=)
AR (1) AR059646A1 (https=)
AU (1) AU2007219569B2 (https=)
BR (1) BRPI0708366A2 (https=)
CA (1) CA2637593C (https=)
CL (2) CL2007000528A1 (https=)
CU (1) CU23558A1 (https=)
ES (1) ES2441441T3 (https=)
MX (1) MX2008011142A (https=)
MY (1) MY184130A (https=)
NO (1) NO20084118L (https=)
RU (1) RU2416618C2 (https=)
WO (1) WO2007098716A1 (https=)
ZA (1) ZA200807162B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4831551B2 (ja) * 2008-11-06 2011-12-07 国立大学法人名古屋大学 非虚血性心筋障害に対する医薬
CU24473B1 (es) * 2016-11-01 2020-02-04 Centro De Ingenieria Genetica Y Biotecnologia Biocubafarma Composición vacunal que comprende un péptido secretagogo de la hormona de crecimiento como adyuvante vacunal
RU2734835C1 (ru) * 2020-02-11 2020-10-23 Федеральное государственное бюджетное учреждение науки Лимнологический институт Сибирского отделение Российской академии наук (ЛИН СО РАН) Способ повышения жизнестойкости эмбрионов рыб в аквакультуре

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3239345A (en) 1965-02-15 1966-03-08 Estrogenic compounds and animal growth promoters
US4411890A (en) 1981-04-14 1983-10-25 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4036979A (en) 1974-01-25 1977-07-19 American Cyanamid Company Compositions containing 4,5,6,7-tetrahydrobenz[b]thien-4-yl-ureas or derivatives and methods of enhancing growth rate
AU637316B2 (en) 1988-01-28 1993-05-27 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
AU628322B2 (en) 1988-01-28 1992-09-17 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
JP2670680B2 (ja) 1988-02-24 1997-10-29 株式会社ビーエムジー 生理活性物質含有ポリ乳酸系微小球およびその製造法
CA2092718C (en) 1990-10-25 2007-08-07 Grace H. W. Wong Use of protective agents against reactive oxygen species
US5663146A (en) 1991-08-22 1997-09-02 Administrators Of The Tulane Educational Fund Polypeptide analogues having growth hormone releasing activity
CA2147503A1 (en) 1992-11-06 1994-05-26 Judith M. Pisano Substituted dipeptide analogs promote release of growth hormone
US5726319A (en) 1992-11-06 1998-03-10 Merck & Co., Inc. Biphenyl substituted dipeptide analogs promote release of growth hormone
WO1994013696A1 (en) 1992-12-11 1994-06-23 Merck & Co., Inc. Spiro piperidines and homologs which promote release of growth hormone
US5578593A (en) 1992-12-11 1996-11-26 Merck & Co., Inc. Spiro piperidines and homologs promote release of growth hormone
HUT75224A (en) 1993-10-19 1997-04-28 Merck & Co Inc Combination of bisphosphonates and growth hormone secretagogues
US5494919A (en) 1993-11-09 1996-02-27 Merck & Co., Inc. 2-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone
US5492916A (en) 1993-12-23 1996-02-20 Merck & Co., Inc. Di- and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone
KR960705808A (ko) 1993-11-09 1996-11-08 조셉 에프. 디프리마 성장 호르몬의 방출을 촉진시키는 피페리딘, 피롤리딘 및 헥사하이드로-1H-아제핀(Piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone)
WO1995014666A1 (en) 1993-11-24 1995-06-01 Merck & Co., Inc. Indolyl group containing compounds and the use thereof to promote the release of growth hormone(s)
US5721251A (en) 1993-12-10 1998-02-24 Merck & Co., Inc. Piperidine, pyrrolidine and hexahydro-1H-azepines promote release of growth hormone
AU683121B2 (en) 1993-12-23 1997-10-30 Novo Nordisk A/S Compounds with growth hormone releasing properties
US5721250A (en) 1993-12-23 1998-02-24 Merck & Co. Inc. Di-and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone
WO1995017423A1 (en) 1993-12-23 1995-06-29 Novo Nordisk A/S Compounds with growth hormone releasing properties
US5777112A (en) 1994-06-13 1998-07-07 Merck & Co., Inc Piperazine compounds promote release of growth hormone
AU3128195A (en) 1994-07-20 1996-02-16 Merck & Co., Inc. Piperidines and hexahydro-1h-azepines spiro substituted at the 4-position promote release of growth hormone
US5798337A (en) 1994-11-16 1998-08-25 Genentech, Inc. Low molecular weight peptidomimetic growth hormone secretagogues
AU4495996A (en) 1995-01-25 1996-08-14 Nippon Chemiphar Co. Ltd. Dihydrophenazine derivatives
ID18218A (id) 1995-01-27 1998-03-19 Novo Nordisk As Senyawa dengan sifat-sifat pelepas hormon pertumbuhan
AU4534696A (en) 1995-02-09 1996-08-27 Novo Nordisk A/S Compounds with growth hormone releasing properties
WO1996024580A1 (en) 1995-02-09 1996-08-15 Novo Nordisk A/S Compounds with growth hormone releasing properties
US5559128A (en) 1995-04-18 1996-09-24 Merck & Co., Inc. 3-substituted piperidines promote release of growth hormone
AU5486396A (en) 1995-04-19 1996-11-07 Merck & Co., Inc. Process for the preparation of spiroindolines
WO1996035713A1 (en) 1995-05-08 1996-11-14 Pfizer, Inc. Dipeptides which promote release of growth hormone
FI974368A7 (fi) 1995-05-29 1997-11-28 Pfizer Kasvuhormonin vapautumista edistäviä dipeptidejä
AU711104B2 (en) 1995-06-22 1999-10-07 Novo Nordisk A/S Compounds with growth hormone releasing properties
EP0761219A1 (en) 1995-08-21 1997-03-12 Eli Lilly And Company 2-Acylaminopropanamines as growth hormone secretagogues
WO1997006803A1 (en) 1995-08-21 1997-02-27 Eli Lilly And Company 2-acylaminopropanamides as growth hormone secretagogues
EP0766966A3 (en) 1995-09-08 2001-02-28 Eli Lilly And Company Method of treating insulin resistance
AU7169696A (en) 1995-09-26 1997-04-17 Merck & Co., Inc. 3-spirolactam, 3-spiroamino, 3-spirolactone and 3-spirobenzopyran piperidines and pyrrolidines promote release of growth hormone
EA199800337A1 (ru) 1995-10-27 1998-10-29 Мерк Энд Ко., Инк. Способ получения гормона роста, усиливающего секрецию
US5767124A (en) 1995-10-27 1998-06-16 Merck & Co., Inc. Polymorphic forms of a growth hormone secretagogue
PL326428A1 (en) 1995-10-27 1998-09-14 Merck & Co Inc Method of obtaining a compound stimulating hormonal secretion of a growth hormone
AU7522896A (en) 1995-10-27 1997-05-15 Merck & Co., Inc. Wet granulation formulation of a growth hormone secretagogue
ES2268713T3 (es) 1995-12-13 2007-03-16 MERCK & CO., INC. Ensayos de receptores de secretagogos de la hormona de crecimiento.
JP3754084B2 (ja) 1995-12-13 2006-03-08 メルク エンド カンパニー インコーポレーテッド 成長ホルモン分泌促進薬受容体ファミリー
IT1277113B1 (it) 1995-12-20 1997-11-04 Romano Deghenghi Composti oligopeptidici contenenti d-2-alchiltriptofano in grado di promuovere la liberazione dell'ormone della crescita
WO1997022367A1 (en) 1995-12-20 1997-06-26 Merck & Co., Inc. Radiolabeled growth hormone secretagogue
CZ195098A3 (cs) * 1995-12-22 1998-10-14 Novo Nordisk A/S Sloučeniny uvolňující růstový hormon
TW432073B (en) 1995-12-28 2001-05-01 Pfizer Pyrazolopyridine compounds
WO1997034604A1 (en) 1996-03-21 1997-09-25 Merck & Co., Inc. 4-spiroindoline piperidines promote release of growth hormone
WO1997036873A1 (en) 1996-04-03 1997-10-09 Merck & Co., Inc. Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone
SE9601397D0 (sv) 1996-04-12 1996-04-12 Pharmacia Ab Use of growth hormone
JP2000510453A (ja) 1996-04-19 2000-08-15 ノボ ノルディスク アクティーゼルスカブ 成長ホルモン遊離特性を有する化合物
US5919777A (en) 1996-04-24 1999-07-06 Novo Nordisk A/S Compounds with growth hormone releasing properties
KR20000010626A (ko) 1996-04-24 2000-02-25 한센 핀 베네드, 안네 제헤르 성장호르몬 방출성을 갖는 화합물
WO1997041878A1 (en) 1996-05-07 1997-11-13 Merck & Co., Inc. Treatment of mood disorders with a growth hormone secretagogue
EP0900086A4 (en) 1996-05-07 2000-01-12 Merck & Co Inc IMPROVING THE SLEEP BY MEANS OF A SUBSTANCE PROMOTING THE SECRETION OF GROWTH HORMONES
WO1997043278A1 (en) 1996-05-14 1997-11-20 Novo Nordisk A/S Somatostatin agonists and antagonists
WO1997044042A1 (en) 1996-05-22 1997-11-27 Arch Development Corporation Sleep quality improvement using a growth hormone secretagogue
PL330239A1 (en) 1996-05-31 1999-05-10 Novo Nordisk As Growt hormone constituent and bone reserption preventing factor in cyclic (coherent) treatment
US5922770A (en) 1996-07-22 1999-07-13 Novo Nordisk A/S Compounds with growth hormone releasing properties
WO1998010653A1 (en) 1996-09-13 1998-03-19 Merck & Co., Inc. Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone
AU4993497A (en) 1996-10-25 1998-05-22 Merck & Co., Inc. Convergent process for the preparation of a growth hormone secretagogue
SE9703929D0 (sv) 1996-11-22 1997-10-28 Pharmacia & Upjohn Ab Therapeutical use and method
AU6747498A (en) 1997-04-11 1998-11-11 Sumitomo Pharmaceuticals Company, Limited Benzene derivatives
JP2000514838A (ja) 1997-05-14 2000-11-07 藤沢薬品工業株式会社 成長ホルモンの放出を促進するピペリジノ誘導体
US5861149A (en) 1997-06-04 1999-01-19 Polyheal Ltd. Methods for wound treatment
EP1005484A1 (en) 1997-06-20 2000-06-07 Novo Nordisk A/S Compounds with growth hormone releasing properties
UA64751C2 (uk) 1997-06-25 2004-03-15 Пфайзер Продактс Інк. Спосіб лікування інсулінової толерантності речовинами, які посилюють секрецію гормону росту (варіанти) та фармацевтична композиція (варіанти)
WO1998058947A1 (en) 1997-06-25 1998-12-30 Pfizer Inc. Dipeptide derivatives as growth hormone secretagogues
UA53716C2 (uk) 1997-06-25 2003-02-17 Пфайзер Продактс Інк. Тартратна сіль заміщеного дипептиду, спосіб її одержання, проміжні сполуки та спосіб їх одержання, фармацевтична композиція (варіанти), спосіб підвищення рівнів ендогенного гормону росту та спосіб лікування або профілактики захворювань (варіанти)
ZA987383B (en) 1997-08-19 2000-02-17 Lilly Co Eli Treatment of congestive heart failure with growth hormone secretagogues.
US6864250B1 (en) 1997-08-22 2005-03-08 Kaken Pharmaceutical Co., Ltd. N-acylated lipophilic amino acid derivatives
HUP0100777A3 (en) 1998-01-16 2001-12-28 Novo Nordisk As Tripeptides with growth hormone releasing properties, pharmaceutical compositions comprising thereof and their use
WO1999039730A1 (en) 1998-02-09 1999-08-12 Kaken Pharmaceutical Co., Ltd. Oral preparations containing peptides promoting the secretion of growth hormone
JP2002505340A (ja) 1998-03-03 2002-02-19 ノボ ノルディスク アクティーゼルスカブ （２ｅ）−５−アミノ−５−メチルヘキセ−２−エン酸ｎ−メチル−ｎ−（（１ｒ）−１−（ｎ−メチル−ｎ−（（１ｒ）−１−（メチルカルバモイル）−２−フェニルエチル）カルバモイル）−２−（２−ナフチル）エチル）アミドの新規な塩
JP4142253B2 (ja) 1998-05-11 2008-09-03 ノボ ノルディスク アクティーゼルスカブ 成長ホルモン放出特性を有する化合物
JP4574849B2 (ja) 1998-06-09 2010-11-04 サファイア セラピューティクス，インコーポレイティド 成長ホルモン放出特性を有する化合物を調製するための方法
CA2335112A1 (en) 1998-06-16 1999-12-23 Hua Zhu Ke Therapeutic combinations for musculoskeletal frailty
ZA993975B (en) 1998-06-16 2000-12-15 Pfizer Prod Inc Combination therapy for musculoskeletal frailty.
DK1100824T3 (da) 1998-06-30 2011-06-20 Helsinn Therapeutics Us Inc Forbindelser med væksthormonfrigivende egenskaber
CA2340701C (en) 1998-08-20 2009-05-26 Sumitomo Pharmaceuticals Co., Ltd. Oxindole derivatives as growth hormone releasers
US6358951B1 (en) 1998-08-21 2002-03-19 Pfizer Inc. Growth hormone secretagogues
CA2395996A1 (en) 1999-12-28 2001-07-05 Kaken Pharmaceutical Co., Ltd. Neuroprotective drug
US6967237B2 (en) 2000-05-30 2005-11-22 Merck & Co., Inc. Ghrelin analogs
DE60140285D1 (de) 2000-05-31 2009-12-10 Pfizer Prod Inc Verwendung von Wachstumshormonsekretagoga zur Förderung der Beweglichkeit des Verdauungstrakts
ATE370119T1 (de) 2000-06-13 2007-09-15 Zentaris Gmbh Wachstumhormonsekretionsförderer
AU2001274601A1 (en) 2000-06-23 2002-01-02 Kaken Pharmaceutical Co., Ltd. Preventives or remedies for heart failure
ITMI20011445A1 (it) 2001-07-06 2003-01-06 Europ Geie Analoghi della cortistantina capaci di legarsi selettivamente ai recettori dei secretagoghi dell'ormone della crescita
CU23043A1 (es) 2001-12-20 2005-05-20 Ct Ingenieria Genetica Biotech Composicion farmaceutica que contiene factor de crecimiento epidrmico (egf) para la prevencion de la amputacion de pie diabetico.
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
WO2005039625A1 (en) 2003-10-28 2005-05-06 Rheoscience A/S Growth hormone secretagogue receptor agonists
US7504506B2 (en) 2003-11-04 2009-03-17 Elixir Pharmaceuticals, Inc. Therapeutic compounds and uses thereof
WO2005048916A2 (en) 2003-11-20 2005-06-02 Biovitrum Ab Tetrahydrospiro-beta-carboline-1,3 '-pyrrolidine derivatives and their use in ghsr-related disorders

Also Published As

Publication number Publication date
AR059646A1 (es) 2008-04-16
US8367620B2 (en) 2013-02-05
ES2441441T3 (es) 2014-02-04
MX2008011142A (es) 2008-09-08
ZA200807162B (en) 2009-06-24
EP1997827B1 (en) 2013-10-09
KR101409277B1 (ko) 2014-06-24
AU2007219569B2 (en) 2012-03-15
JP5183496B2 (ja) 2013-04-17
RU2416618C2 (ru) 2011-04-20
EP1997827A1 (en) 2008-12-03
US20100055118A1 (en) 2010-03-04
CU23558A1 (es) 2010-07-20
WO2007098716A8 (es) 2008-12-18
CA2637593C (en) 2015-04-14
CA2637593A1 (en) 2007-09-07
RU2008138569A (ru) 2010-04-10
CL2016001648A1 (es) 2017-02-24
CN101432294A (zh) 2009-05-13
NO20084118L (no) 2008-09-29
WO2007098716A1 (es) 2007-09-07
JP2009528303A (ja) 2009-08-06
KR20080110763A (ko) 2008-12-19
BRPI0708366A2 (pt) 2011-05-24
AU2007219569A1 (en) 2007-09-07
CN101432294B (zh) 2013-09-11
CL2007000528A1 (es) 2008-01-18

Similar Documents

Publication Publication Date Title
PH12012502314A1 (en) Tube feed packages and methods for using same
ZA200810840B (en) Extracts of aphanizomenon flos aquae and nutritional, cosmetic and pharmaceutical compositions containing the same
MX2009012255A (es) Probioticos en ambiente pre y/o postquirurgico.
MX2010003574A (es) Anticuerpos il-23.
MX2009007014A (es) Carne molida y composiciones analogas de carne que tienen mayores propiedades nutritivas.
DK2073789T3 (da) Stabil sammensætning omfattende et knogle-anabolisk protein, nemlig en pthrp-analog, og anvendelser deraf
NO20090348L (no) Substituerte imidazolonderivater, sammensetninger og anvendelser av samme, samt fremgangsmater for fremstilling av samme
MY162324A (en) Immunomodulatory polypeptides derived from il-2 and their use thereof in the therapeutic of cancer and chronic infections
MX2007003013A (es) Amidas biciclicas como inhibidores de cinasa.
WO2009025196A1 (ja) Foxm1ペプチドおよびこれを含む薬剤
WO2008087367A3 (fr) Derives de (phenylthiazolyl)-phenyl-propan-1-one et de (phenyloxazodyl)-phenyl-propan-1-one substitues, preparations et utilisations
UA91044C2 (uk) Жива послаблена ротавірусна вакцина для перорального застосування
CY1116269T1 (el) Χρηση μιας πρωτεϊνης απο λουπινο
MY150226A (en) Novel h5 proteins, nucleic acid molecules and vectors encoding for those, and medicinal use
WO2006137069A3 (en) Balanites aegyptiaca saponins and uses thereof
MX2009003239A (es) Alimentacion de ancianos a largo plazo.
CY1108138T1 (el) Χρησιμοποιηση λουπινοκονγλουτινης δια την θεραπευτικη αγωγη διαβητου τυπου ιι
NZ596501A (en) Casb7439 constructs
MY184130A (en) Peptidic growth hormone secretagogues analog compounds and preparations thereof
WO2004039326A3 (en) Propofol with cysteine
MX2007004879A (es) Proteccion de ingredientes de alimentos bioactivos por medio de encapsulacion.
ATE452120T1 (de) Fettsäure-benzenediol-derivate sowie herstellungs-und verwendungsverfahren dafür
WO2006109194A3 (en) Chromium-fatty acid compounds and methods of making and using thereof
MXPA06002648A (es) Fracciones de leche y preparaciones de leche para el tratamiento y/o prevencion de las enfermedades medidas por cox-2.
PL1615656T3 (pl) Produkt immunomodulatorowy otrzymany z hodowli bifidobacterium i zawierające go kompozycje