UA91044C2 - Жива послаблена ротавірусна вакцина для перорального застосування - Google Patents
Жива послаблена ротавірусна вакцина для перорального застосуванняInfo
- Publication number
- UA91044C2 UA91044C2 UAA200708765A UAA200708765A UA91044C2 UA 91044 C2 UA91044 C2 UA 91044C2 UA A200708765 A UAA200708765 A UA A200708765A UA A200708765 A UAA200708765 A UA A200708765A UA 91044 C2 UA91044 C2 UA 91044C2
- Authority
- UA
- Ukraine
- Prior art keywords
- oral administration
- live attenuated
- rotavirus vaccine
- attenuated rotavirus
- phosphate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/15—Reoviridae, e.g. calf diarrhea virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Abstract
Винахід стосується рідких ротавірусних композицій для перорального призначення малюкам людини, що містять ротавірусний антиген, цукор та карбоксилат, який є похідним дикарбонової кислоти. Вказана композиція має рН між 5,0 та 8,0 та містить менше 1 мМ фосфату.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0503337.8A GB0503337D0 (en) | 2005-02-17 | 2005-02-17 | Compositions |
PCT/EP2006/001442 WO2006087205A1 (en) | 2005-02-17 | 2006-02-15 | Live attenuated rotavirus vaccine for oral administration |
Publications (1)
Publication Number | Publication Date |
---|---|
UA91044C2 true UA91044C2 (uk) | 2010-06-25 |
Family
ID=34385675
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200708765A UA91044C2 (uk) | 2005-02-17 | 2006-02-15 | Жива послаблена ротавірусна вакцина для перорального застосування |
Country Status (32)
Country | Link |
---|---|
US (2) | US8192747B2 (uk) |
EP (2) | EP1863526B1 (uk) |
JP (1) | JP5118977B2 (uk) |
KR (1) | KR101319846B1 (uk) |
CN (2) | CN103357005A (uk) |
AP (1) | AP2692A (uk) |
AR (1) | AR053680A1 (uk) |
AT (1) | ATE516044T1 (uk) |
AU (1) | AU2006215761B2 (uk) |
BR (1) | BRPI0608877B8 (uk) |
CA (1) | CA2598290C (uk) |
CY (1) | CY1111916T1 (uk) |
DK (1) | DK1863526T3 (uk) |
EA (1) | EA012046B1 (uk) |
ES (1) | ES2369246T3 (uk) |
GB (1) | GB0503337D0 (uk) |
HR (1) | HRP20110668T1 (uk) |
IL (1) | IL184802A0 (uk) |
MA (1) | MA29321B1 (uk) |
MX (1) | MX2007010075A (uk) |
MY (1) | MY145790A (uk) |
NO (1) | NO341789B1 (uk) |
NZ (1) | NZ560314A (uk) |
PE (1) | PE20061094A1 (uk) |
PL (1) | PL1863526T3 (uk) |
PT (1) | PT1863526E (uk) |
SI (1) | SI1863526T1 (uk) |
TW (1) | TWI358303B (uk) |
UA (1) | UA91044C2 (uk) |
UY (1) | UY29377A1 (uk) |
WO (1) | WO2006087205A1 (uk) |
ZA (1) | ZA200706668B (uk) |
Families Citing this family (35)
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WO2007132480A2 (en) * | 2006-05-12 | 2007-11-22 | Bharat Biotech International Limited | A composition useful as a vaccine |
WO2009042202A2 (en) | 2007-09-25 | 2009-04-02 | Aridis Pharmaceuticals | Formulations for preservation of rota virus |
EP2236617A1 (en) | 2009-03-31 | 2010-10-06 | Leukocare Ag | Methods of terminal sterilization of biofunctional compositions |
US8822192B2 (en) | 2009-05-12 | 2014-09-02 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human rotavirus vaccine strains and diagnostics |
CN101972475B (zh) * | 2010-04-12 | 2014-04-09 | 李建平 | 一种细菌多糖-蛋白结合疫苗及其制备方法 |
CN101863966B (zh) * | 2010-05-21 | 2012-10-03 | 中国人民解放军第三军医大学 | 抗轮状病毒药物作用靶标及其构建方法和应用方法 |
EP3970715A1 (en) | 2010-09-24 | 2022-03-23 | University of Florida Research Foundation, Inc. | Materials and methods for improving gastrointestinal function |
EP2471554A1 (en) | 2010-12-28 | 2012-07-04 | Hexal AG | Pharmaceutical formulation comprising a biopharmaceutical drug |
WO2012103472A1 (en) * | 2011-01-28 | 2012-08-02 | Brian Pulliam | Granularized particular thermostable rotovirus vaccine preparation |
US20140242113A1 (en) * | 2011-04-28 | 2014-08-28 | Leonard P. Ruiz, JR. | Liquid vaccine preparations |
CN102349932B (zh) * | 2011-10-12 | 2012-12-26 | 刘壮华 | 一种治疗息肉的药物制剂 |
WO2013105105A2 (en) * | 2012-01-13 | 2013-07-18 | Serum Institute Of India Ltd. | Novel viral vaccine compositions and methods for preparing such vaccines |
US20140377374A1 (en) * | 2012-02-08 | 2014-12-25 | University Of Florida Research Foundation, Inc. | Materials and methods for treating diarrhea |
JP6253161B2 (ja) | 2012-03-05 | 2017-12-27 | デ スタート デル ネーデルランデン, ヴェルト. ドール デ ミニステル ヴァン ヴイダブリューエス ミニステリー ヴァン ボルクスゲツォントヘイト, ベルジーン エン シュポルトDe Staat Der Nederlanden, Vert. Door De Minister Van Vws Ministerie Van Volksgezondheid, Welzijn En Sport | 乾燥された生物学的材料を安定化するための方法及び組成物 |
WO2013160913A1 (en) | 2012-04-23 | 2013-10-31 | Bharat Biotech International Limited | Rotavirus vaccine compositions and process for preparing the same |
US9314519B2 (en) | 2012-08-21 | 2016-04-19 | Intervet Inc. | Liquid stable virus vaccines |
WO2014164736A1 (en) | 2013-03-11 | 2014-10-09 | University Of Florida Research Foundation, Incorporated | Materials and methods for improving lung function and for prevention and/or treatment of radiation-induced lung complications |
US9393298B2 (en) | 2013-03-15 | 2016-07-19 | Intervet Inc. | Liquid stable bovine virus vaccines |
US9480739B2 (en) | 2013-03-15 | 2016-11-01 | Intervet Inc. | Bovine virus vaccines that are liquid stable |
CN103316336B (zh) * | 2013-05-31 | 2015-01-28 | 北京科兴中维生物技术有限公司 | 一种适于口服的轮状病毒疫苗 |
CN103316335B (zh) * | 2013-05-31 | 2014-11-12 | 北京科兴生物制品有限公司 | 一种适于口服的脊髓灰质炎病毒疫苗 |
RU2662558C2 (ru) * | 2013-07-19 | 2018-07-26 | Хексаль Аг | Способы и композиции, которые обеспечивают модуляцию иммунных ответов, связанных с введением биофармацевтического лекарственного средства |
AR097762A1 (es) | 2013-09-27 | 2016-04-13 | Intervet Int Bv | Formulaciones secas de vacunas que son estables a temperatura ambiente |
US20160206728A1 (en) * | 2013-10-03 | 2016-07-21 | Nitto Denko Corporation | Dried influenza vaccine preparation and method of producing the same |
AR099470A1 (es) | 2014-02-17 | 2016-07-27 | Intervet Int Bv | Vacunas de virus de aves de corral líquidas |
TWI670085B (zh) | 2014-02-19 | 2019-09-01 | 荷蘭商英特威國際公司 | 液體穩定之豬病毒疫苗 |
CN113730564A (zh) * | 2014-12-08 | 2021-12-03 | 武汉生物制品研究所有限责任公司 | 口服六价重配轮状病毒活疫苗 |
CN108431214B (zh) | 2015-10-05 | 2022-03-01 | 美国政府(由卫生和人类服务部的部长所代表) | 人轮状病毒g9p[6]毒株和作为疫苗的用途 |
US10874732B2 (en) * | 2015-12-18 | 2020-12-29 | Merck Sharp & Dohme Corp. | Thermally stable rotavirus vaccine formulations and methods of use thereof |
MA44557B1 (fr) | 2016-06-16 | 2021-11-30 | Bharat Biotech Int Ltd | Vaccin contre le rotavirus sans tampon, stable en milieu acide, et d'un faible volume de dose à administrer |
GB201614799D0 (en) * | 2016-09-01 | 2016-10-19 | Glaxosmithkline Biologicals Sa | Compositions |
BR112020021134A2 (pt) * | 2018-04-16 | 2021-03-23 | Merck Patent Gmbh | aditivos para formulações de proteínas para aprimorar estabilidade térmica |
CN110946871A (zh) * | 2019-12-12 | 2020-04-03 | 浙江华康药业股份有限公司 | 槐糖在制备预防和治疗肥胖产品中的应用及对应产品 |
CN115531364B (zh) * | 2021-06-30 | 2024-02-23 | 中国科学技术大学 | 预防或治疗轮状病毒感染的微生物代谢物制剂及其用途 |
CN113994925B (zh) * | 2021-12-30 | 2022-04-26 | 北京赛尔富森生物科技有限公司 | 一种轮状病毒攻毒动物模型及其建立方法 |
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PT1212084E (pt) * | 1999-08-17 | 2006-07-31 | Glaxosmithkline Biolog Sa | Metodos para separar variantes do rotavirus e vacina do rotavirus vivo atenuado |
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-
2005
- 2005-02-17 GB GBGB0503337.8A patent/GB0503337D0/en not_active Ceased
-
2006
- 2006-02-15 WO PCT/EP2006/001442 patent/WO2006087205A1/en active Application Filing
- 2006-02-15 NZ NZ560314A patent/NZ560314A/en not_active IP Right Cessation
- 2006-02-15 BR BRPI0608877A patent/BRPI0608877B8/pt active IP Right Grant
- 2006-02-15 AT AT06707035T patent/ATE516044T1/de active
- 2006-02-15 EP EP06707035A patent/EP1863526B1/en active Active
- 2006-02-15 PT PT06707035T patent/PT1863526E/pt unknown
- 2006-02-15 EP EP10180343A patent/EP2322211A1/en not_active Withdrawn
- 2006-02-15 KR KR1020077021142A patent/KR101319846B1/ko active IP Right Grant
- 2006-02-15 PE PE2006000184A patent/PE20061094A1/es not_active Application Discontinuation
- 2006-02-15 AU AU2006215761A patent/AU2006215761B2/en active Active
- 2006-02-15 AP AP2007004087A patent/AP2692A/xx active
- 2006-02-15 MY MYPI20060654A patent/MY145790A/en unknown
- 2006-02-15 CN CN2013103024516A patent/CN103357005A/zh active Pending
- 2006-02-15 CN CN200680005318.2A patent/CN101300028B/zh active Active
- 2006-02-15 ES ES06707035T patent/ES2369246T3/es active Active
- 2006-02-15 MX MX2007010075A patent/MX2007010075A/es active IP Right Grant
- 2006-02-15 PL PL06707035T patent/PL1863526T3/pl unknown
- 2006-02-15 UY UY29377A patent/UY29377A1/es unknown
- 2006-02-15 JP JP2007555532A patent/JP5118977B2/ja active Active
- 2006-02-15 AR ARP060100551A patent/AR053680A1/es not_active Application Discontinuation
- 2006-02-15 TW TW095105102A patent/TWI358303B/zh not_active IP Right Cessation
- 2006-02-15 US US11/816,443 patent/US8192747B2/en active Active
- 2006-02-15 SI SI200631128T patent/SI1863526T1/sl unknown
- 2006-02-15 DK DK06707035.9T patent/DK1863526T3/da active
- 2006-02-15 UA UAA200708765A patent/UA91044C2/uk unknown
- 2006-02-15 EA EA200701519A patent/EA012046B1/ru not_active IP Right Cessation
- 2006-02-15 CA CA2598290A patent/CA2598290C/en active Active
-
2007
- 2007-07-24 NO NO20073868A patent/NO341789B1/no unknown
- 2007-07-24 IL IL184802A patent/IL184802A0/en active IP Right Grant
- 2007-08-10 ZA ZA200706668A patent/ZA200706668B/xx unknown
- 2007-09-10 MA MA30201A patent/MA29321B1/fr unknown
-
2011
- 2011-09-15 HR HR20110668T patent/HRP20110668T1/hr unknown
- 2011-10-06 CY CY20111100959T patent/CY1111916T1/el unknown
-
2012
- 2012-06-01 US US13/486,039 patent/US8821891B2/en active Active
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