DK1863526T3 - Levende, attenueret rotavirusvaccine til oral indgivelse - Google Patents

Levende, attenueret rotavirusvaccine til oral indgivelse

Info

Publication number
DK1863526T3
DK1863526T3 DK06707035.9T DK06707035T DK1863526T3 DK 1863526 T3 DK1863526 T3 DK 1863526T3 DK 06707035 T DK06707035 T DK 06707035T DK 1863526 T3 DK1863526 T3 DK 1863526T3
Authority
DK
Denmark
Prior art keywords
oral administration
live attenuated
rotavirus vaccine
attenuated rotavirus
vaccine
Prior art date
Application number
DK06707035.9T
Other languages
English (en)
Inventor
Velde Vincent Vande
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34385675&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1863526(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Application granted granted Critical
Publication of DK1863526T3 publication Critical patent/DK1863526T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/15—Reoviridae, e.g. calf diarrhea virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DK06707035.9T 2005-02-17 2006-02-15 Levende, attenueret rotavirusvaccine til oral indgivelse DK1863526T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0503337.8A GB0503337D0 (en) 2005-02-17 2005-02-17 Compositions
PCT/EP2006/001442 WO2006087205A1 (en) 2005-02-17 2006-02-15 Live attenuated rotavirus vaccine for oral administration

Publications (1)

Publication Number Publication Date
DK1863526T3 true DK1863526T3 (da) 2011-10-24

Family

ID=34385675

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06707035.9T DK1863526T3 (da) 2005-02-17 2006-02-15 Levende, attenueret rotavirusvaccine til oral indgivelse

Country Status (32)

Country Link
US (2) US8192747B2 (da)
EP (2) EP2322211A1 (da)
JP (1) JP5118977B2 (da)
KR (1) KR101319846B1 (da)
CN (2) CN101300028B (da)
AP (1) AP2692A (da)
AR (1) AR053680A1 (da)
AT (1) ATE516044T1 (da)
AU (1) AU2006215761B2 (da)
BR (1) BRPI0608877B8 (da)
CA (1) CA2598290C (da)
CY (1) CY1111916T1 (da)
DK (1) DK1863526T3 (da)
EA (1) EA012046B1 (da)
ES (1) ES2369246T3 (da)
GB (1) GB0503337D0 (da)
HR (1) HRP20110668T1 (da)
IL (1) IL184802A0 (da)
MA (1) MA29321B1 (da)
MX (1) MX2007010075A (da)
MY (1) MY145790A (da)
NO (1) NO341789B1 (da)
NZ (1) NZ560314A (da)
PE (1) PE20061094A1 (da)
PL (1) PL1863526T3 (da)
PT (1) PT1863526E (da)
SI (1) SI1863526T1 (da)
TW (1) TWI358303B (da)
UA (1) UA91044C2 (da)
UY (1) UY29377A1 (da)
WO (1) WO2006087205A1 (da)
ZA (1) ZA200706668B (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2008014391A (es) * 2006-05-12 2009-03-06 Bharat Biotech Int Ltd Una composicion util como vacuna.
EP2197283B1 (en) * 2007-09-25 2013-07-17 Aridis Pharmaceuticals Formulations for preservation of rota virus
EP2236617A1 (en) 2009-03-31 2010-10-06 Leukocare Ag Methods of terminal sterilization of biofunctional compositions
US8822192B2 (en) 2009-05-12 2014-09-02 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Human rotavirus vaccine strains and diagnostics
CN101972475B (zh) * 2010-04-12 2014-04-09 李建平 一种细菌多糖-蛋白结合疫苗及其制备方法
CN101863966B (zh) * 2010-05-21 2012-10-03 中国人民解放军第三军医大学 抗轮状病毒药物作用靶标及其构建方法和应用方法
AP2013006826A0 (en) 2010-09-24 2013-04-30 Univ Florida Materials and methods for improving gastrointestinal function
EP2471554A1 (en) * 2010-12-28 2012-07-04 Hexal AG Pharmaceutical formulation comprising a biopharmaceutical drug
WO2012103472A1 (en) * 2011-01-28 2012-08-02 Brian Pulliam Granularized particular thermostable rotovirus vaccine preparation
JP2014512410A (ja) * 2011-04-28 2014-05-22 インターナショナル メディカ ファウンデーション 液体ワクチン調製物
CN102349932B (zh) * 2011-10-12 2012-12-26 刘壮华 一种治疗息肉的药物制剂
WO2013105105A2 (en) * 2012-01-13 2013-07-18 Serum Institute Of India Ltd. Novel viral vaccine compositions and methods for preparing such vaccines
KR102262179B1 (ko) * 2012-02-08 2021-06-07 유니버시티 오브 플로리다 리서치 파운데이션, 인크. 설사를 치료하기 위한 물질 및 방법
KR102108876B1 (ko) * 2012-03-05 2020-05-12 드 슈타트 데르 네덜란덴, 베르테겐부어디그트 두어 드 미니스터 반 베이웨이에스, 미니스테리 반 폭스겐트존하이트, 벨지인 엔 스포츠 건조된 생물학적 물질을 안정화시키는 방법 및 조성물
CN110227152A (zh) 2012-04-23 2019-09-13 巴拉特生物技术国际有限公司 轮状病毒疫苗组合物及其制备方法
US9314519B2 (en) 2012-08-21 2016-04-19 Intervet Inc. Liquid stable virus vaccines
CN110522744B (zh) 2013-03-11 2023-04-07 佛罗里达大学研究基金会有限公司 用于改善肺功能和用于预防和/或治疗辐射诱发的肺并发症的材料和方法
US9480739B2 (en) 2013-03-15 2016-11-01 Intervet Inc. Bovine virus vaccines that are liquid stable
US9393298B2 (en) 2013-03-15 2016-07-19 Intervet Inc. Liquid stable bovine virus vaccines
CN103316336B (zh) * 2013-05-31 2015-01-28 北京科兴中维生物技术有限公司 一种适于口服的轮状病毒疫苗
CN103316335B (zh) * 2013-05-31 2014-11-12 北京科兴生物制品有限公司 一种适于口服的脊髓灰质炎病毒疫苗
CA2914776C (en) * 2013-07-19 2018-08-07 Hexal Ag Methods and formulations which allow the modulation of immune responses related to the administration of a biopharmaceutical drug
AR097762A1 (es) 2013-09-27 2016-04-13 Intervet Int Bv Formulaciones secas de vacunas que son estables a temperatura ambiente
WO2015050177A1 (ja) * 2013-10-03 2015-04-09 日東電工株式会社 インフルエンザワクチン乾燥製剤、及び、インフルエンザワクチン乾燥製剤の製造方法
AR099470A1 (es) 2014-02-17 2016-07-27 Intervet Int Bv Vacunas de virus de aves de corral líquidas
TWI670085B (zh) 2014-02-19 2019-09-01 荷蘭商英特威國際公司 液體穩定之豬病毒疫苗
CN113730564A (zh) * 2014-12-08 2021-12-03 武汉生物制品研究所有限责任公司 口服六价重配轮状病毒活疫苗
US10548970B2 (en) 2015-10-05 2020-02-04 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Human rotavirus G9P[6] strain and use as a vaccine
KR20180095817A (ko) * 2015-12-18 2018-08-28 머크 샤프 앤드 돔 코포레이션 열적으로 안정한 로타바이러스 백신 제제 및 그의 사용 방법
MA44557B1 (fr) 2016-06-16 2021-11-30 Bharat Biotech Int Ltd Vaccin contre le rotavirus sans tampon, stable en milieu acide, et d'un faible volume de dose à administrer
GB201614799D0 (en) * 2016-09-01 2016-10-19 Glaxosmithkline Biologicals Sa Compositions
KR20200144120A (ko) * 2018-04-16 2020-12-28 메르크 파텐트 게엠베하 열 안정성을 개선하기 위한 단백질 제제에 대한 첨가제
CN110946871A (zh) * 2019-12-12 2020-04-03 浙江华康药业股份有限公司 槐糖在制备预防和治疗肥胖产品中的应用及对应产品
CN115531364B (zh) * 2021-06-30 2024-02-23 中国科学技术大学 预防或治疗轮状病毒感染的微生物代谢物制剂及其用途
CN113994925B (zh) * 2021-12-30 2022-04-26 北京赛尔富森生物科技有限公司 一种轮状病毒攻毒动物模型及其建立方法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2505657A1 (fr) 1981-05-13 1982-11-19 Pasteur Institut Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation
US4436727A (en) 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
SE8205892D0 (sv) 1982-10-18 1982-10-18 Bror Morein Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
CA1331443C (en) 1987-05-29 1994-08-16 Charlotte A. Kensil Saponin adjuvant
JP2849632B2 (ja) 1988-04-08 1999-01-20 社団法人北里研究所 ワクチン製剤
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
CA2096315C (en) 1990-11-16 1996-11-19 Richard L. Ward Human rotaviruses, vaccines and methods
NZ240818A (en) * 1990-12-14 1993-08-26 Mcneil Ppc Inc Liquid sucralose concentrate compositions containing preservative, buffer and liquid
EP0535723A1 (en) * 1991-08-05 1993-04-07 Sterling Winthrop Inc. Buffered formulation of capitals
CA2085827C (en) 1991-12-23 2003-10-14 Lucas A. T. Hilgers Adjuvant composition containing synthetic hydrophobic lipopolysaccharide
IT1253009B (it) 1991-12-31 1995-07-10 Sclavo Ricerca S R L Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini
PL170980B1 (pl) 1992-06-25 1997-02-28 Smithkline Beecham Biolog Szczepionka PL PL PL PL PL PL PL
CZ289476B6 (cs) 1993-03-23 2002-01-16 Smithkline Beecham Biologicals (S.A.) Očkovací přípravek a způsob jeho výroby
ATE195740T1 (de) 1993-11-17 2000-09-15 Om Pharma Glucosamin-disaccharide, verfahren zu deren herstellung, pharmazeutische präparate davon und ihre verwendung
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
US6019982A (en) 1994-08-26 2000-02-01 The Administrators Of The Tulane Educational Fund Mutant enterotoxin effective as a non-toxic oral adjuvant
AUPM873294A0 (en) 1994-10-12 1994-11-03 Csl Limited Saponin preparations and use thereof in iscoms
GB9620795D0 (en) 1996-10-05 1996-11-20 Smithkline Beecham Plc Vaccines
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
US5932223A (en) * 1996-09-26 1999-08-03 Merck & Co., Inc. Rotavirus vaccine formulations
EP0939648B1 (en) 1996-09-26 2007-11-07 Merck & Co., Inc. Rotavirus vaccine formulations
US6403098B1 (en) * 1996-09-26 2002-06-11 Merck & Co., Inc. Rotavirus vaccine formulations
US6616931B1 (en) * 1996-09-26 2003-09-09 Merck & Co., Inc. Rotavirus vaccine formulations
WO1998043670A2 (en) 1997-04-01 1998-10-08 Ribi Immunochem Research, Inc. Aqueous immunologic adjuvant compositions of monophosphoryl lipid a
WO1998056415A1 (en) 1997-06-11 1998-12-17 Aquila Biopharmaceuticals, Inc. Purified saponins as oral adjuvants
GB9718901D0 (en) 1997-09-05 1997-11-12 Smithkline Beecham Biolog Vaccine
EP1279401B1 (en) 1997-09-05 2008-01-09 GlaxoSmithKline Biologicals S.A. Oil in water emulsions containing saponins
GB9725084D0 (en) * 1997-11-28 1998-01-28 Medeva Europ Ltd Vaccine compositions
US6919076B1 (en) * 1998-01-20 2005-07-19 Pericor Science, Inc. Conjugates of agents and transglutaminase substrate linking molecules
AU7924598A (en) 1998-06-08 1999-12-30 Sca Emballage France Fast flattening packaging
PL195764B1 (pl) 1998-06-30 2007-10-31 Om Pharma Pseudodipeptydy N-acylowe, sposoby wytwarzania pseudodipeptydów N-acylowych i kompozycje farmaceutyczne
DE60028390T2 (de) * 1999-08-17 2006-11-02 Glaxosmithkline Biologicals S.A. Methoden um rotavirusvarianten zu trennen und lebender attenuierter rotavirus impfstoff
AU1581400A (en) 1999-12-22 2001-07-03 Om Pharma Acyl pseudopeptides bearing a functionalised auxiliary spacer
AU784344B2 (en) * 2000-01-28 2006-03-16 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Compositions and method for preventing reactogenicity associated with administration of immunogenic live rotavirus compositions

Also Published As

Publication number Publication date
JP5118977B2 (ja) 2013-01-16
UA91044C2 (uk) 2010-06-25
EA012046B1 (ru) 2009-08-28
AP2692A (en) 2013-07-16
UY29377A1 (es) 2006-10-02
US20080166372A1 (en) 2008-07-10
MY145790A (en) 2012-04-30
CA2598290A1 (en) 2006-08-24
HRP20110668T1 (hr) 2011-10-31
US8192747B2 (en) 2012-06-05
KR101319846B1 (ko) 2013-10-22
MX2007010075A (es) 2008-01-16
NZ560314A (en) 2011-02-25
CN101300028A (zh) 2008-11-05
MA29321B1 (fr) 2008-03-03
ATE516044T1 (de) 2011-07-15
NO20073868L (no) 2007-11-15
TW200640486A (en) 2006-12-01
BRPI0608877B1 (pt) 2021-02-09
EP2322211A1 (en) 2011-05-18
US20120237547A1 (en) 2012-09-20
AR053680A1 (es) 2007-05-16
PL1863526T3 (pl) 2011-12-30
BRPI0608877B8 (pt) 2021-05-25
SI1863526T1 (sl) 2011-11-30
GB0503337D0 (en) 2005-03-23
EP1863526B1 (en) 2011-07-13
JP2008530165A (ja) 2008-08-07
BRPI0608877A2 (pt) 2012-07-31
ZA200706668B (en) 2009-07-29
AU2006215761B2 (en) 2011-03-17
CA2598290C (en) 2015-08-11
CN103357005A (zh) 2013-10-23
EP1863526A1 (en) 2007-12-12
WO2006087205A1 (en) 2006-08-24
KR20070103506A (ko) 2007-10-23
AP2007004087A0 (en) 2007-08-31
CN101300028B (zh) 2014-06-04
TWI358303B (en) 2012-02-21
IL184802A0 (en) 2007-12-03
PE20061094A1 (es) 2006-11-30
CY1111916T1 (el) 2015-11-04
EA200701519A1 (ru) 2008-02-28
AU2006215761A1 (en) 2006-08-24
NO341789B1 (no) 2018-01-22
US8821891B2 (en) 2014-09-02
PT1863526E (pt) 2011-10-11
ES2369246T3 (es) 2011-11-28

Similar Documents

Publication Publication Date Title
DK1863526T3 (da) Levende, attenueret rotavirusvaccine til oral indgivelse
DK2066354T3 (da) Norovirus vaccine formuleringer
ATE462445T1 (de) Prrs-impfstoffe
DK3984528T3 (da) Farmaceutiske sammensætninger, som omfatter nilotinib
DK1896061T3 (da) Immunogen sammensætning
NL2000690A1 (nl) Gestabiliseerde farmaceutische samenstellingen omvattende fesoterodine.
DK1968631T3 (da) Vaccine
DK2139494T3 (da) Farmaceutiske formuleringer, der indeholder dapagliflozin-propylenglycolhydrat
NO20075628L (no) Farmasøytiske formuleringer
BRPI0810646A2 (pt) " compostos farmacêuticos ".
BRPI0820997A2 (pt) Comprimidos de desintegração oral compreendendo difenidramina.
ATE516817T1 (de) Impfstoffe zur immunisierung gegen helicobacter
DK3072507T3 (da) Farmaceutiske sammensætninger til glukokortikoidsubstitutionsterapi
DK2051975T3 (da) Substituerede prolinamider, fremstilling deraf og anvendelse deraf som lægemiddel.
DK1729819T3 (da) Indgivelsesanordning til lægemidler, som er röntgenstråle-synlige
ITTO20050241A1 (it) Impianto dentario intraosseo.
EP1856250A4 (en) NEW VACCINES LIVING VIRUSES
DK2233153T3 (da) Rotavirus-vaccine, som inducerer heterotypisk krydsbeskyttelse
AP2695A (en) Vaccine adjuvants
ITFI20080016A1 (it) Formulazioni farmaceutiche orali contenenti gliclazide.
EP2054081A4 (en) VACCINE AGAINST THE JC VIRUS
FR2925058B1 (fr) Maltitol parallelepipede rectangulaire.
FR2903887B1 (fr) Seringue perfectionnee pour administration orale.
ES2365717T5 (es) Vacunacion meningococica conjugada.
ATE428416T1 (de) Feste pharmazeutische zubereitung enthaltend (r)- (-)-2-ä5-(4-fluorophenyl)-3- pyridylmethylaminomethylü-chroman