AR059646A1 - Compuestos analogos a los secretagogos peptidicos de la hormona de crecimiento y preparaciones que los contienen - Google Patents
Compuestos analogos a los secretagogos peptidicos de la hormona de crecimiento y preparaciones que los contienenInfo
- Publication number
- AR059646A1 AR059646A1 ARP070100806A ARP070100806A AR059646A1 AR 059646 A1 AR059646 A1 AR 059646A1 AR P070100806 A ARP070100806 A AR P070100806A AR P070100806 A ARP070100806 A AR P070100806A AR 059646 A1 AR059646 A1 AR 059646A1
- Authority
- AR
- Argentina
- Prior art keywords
- amino acids
- peptide
- thr
- leu
- gly
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 102000018997 Growth Hormone Human genes 0.000 title abstract 2
- 108010051696 Growth Hormone Proteins 0.000 title abstract 2
- 239000000122 growth hormone Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000008575 L-amino acids Chemical class 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- BGHSOEHUOOAYMY-JTZMCQEISA-N ghrelin Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)CN)C1=CC=CC=C1 BGHSOEHUOOAYMY-JTZMCQEISA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000000580 secretagogue effect Effects 0.000 abstract 2
- 101800001586 Ghrelin Proteins 0.000 abstract 1
- 102000012004 Ghrelin Human genes 0.000 abstract 1
- 150000001413 amino acids Chemical group 0.000 abstract 1
- 239000013043 chemical agent Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- -1 compound amino acid Chemical class 0.000 abstract 1
- 108010051768 des-n-octanoyl ghrelin Proteins 0.000 abstract 1
- 235000015872 dietary supplement Nutrition 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 238000000126 in silico method Methods 0.000 abstract 1
- 238000000302 molecular modelling Methods 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20060050A CU23558A1 (es) | 2006-02-28 | 2006-02-28 | Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR059646A1 true AR059646A1 (es) | 2008-04-16 |
Family
ID=40130780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070100806A AR059646A1 (es) | 2006-02-28 | 2007-02-27 | Compuestos analogos a los secretagogos peptidicos de la hormona de crecimiento y preparaciones que los contienen |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8367620B2 (https=) |
| EP (1) | EP1997827B1 (https=) |
| JP (1) | JP5183496B2 (https=) |
| KR (1) | KR101409277B1 (https=) |
| CN (1) | CN101432294B (https=) |
| AR (1) | AR059646A1 (https=) |
| AU (1) | AU2007219569B2 (https=) |
| BR (1) | BRPI0708366A2 (https=) |
| CA (1) | CA2637593C (https=) |
| CL (2) | CL2007000528A1 (https=) |
| CU (1) | CU23558A1 (https=) |
| ES (1) | ES2441441T3 (https=) |
| MX (1) | MX2008011142A (https=) |
| MY (1) | MY184130A (https=) |
| NO (1) | NO20084118L (https=) |
| RU (1) | RU2416618C2 (https=) |
| WO (1) | WO2007098716A1 (https=) |
| ZA (1) | ZA200807162B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4831551B2 (ja) * | 2008-11-06 | 2011-12-07 | 国立大学法人名古屋大学 | 非虚血性心筋障害に対する医薬 |
| CU24473B1 (es) * | 2016-11-01 | 2020-02-04 | Centro De Ingenieria Genetica Y Biotecnologia Biocubafarma | Composición vacunal que comprende un péptido secretagogo de la hormona de crecimiento como adyuvante vacunal |
| RU2734835C1 (ru) * | 2020-02-11 | 2020-10-23 | Федеральное государственное бюджетное учреждение науки Лимнологический институт Сибирского отделение Российской академии наук (ЛИН СО РАН) | Способ повышения жизнестойкости эмбрионов рыб в аквакультуре |
Family Cites Families (92)
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| UA53716C2 (uk) | 1997-06-25 | 2003-02-17 | Пфайзер Продактс Інк. | Тартратна сіль заміщеного дипептиду, спосіб її одержання, проміжні сполуки та спосіб їх одержання, фармацевтична композиція (варіанти), спосіб підвищення рівнів ендогенного гормону росту та спосіб лікування або профілактики захворювань (варіанти) |
| UA64751C2 (uk) | 1997-06-25 | 2004-03-15 | Пфайзер Продактс Інк. | Спосіб лікування інсулінової толерантності речовинами, які посилюють секрецію гормону росту (варіанти) та фармацевтична композиція (варіанти) |
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| IL137007A0 (en) | 1998-01-16 | 2001-06-14 | Novo Nordisk As | Compounds with growth hormone releasing properties |
| WO1999039730A1 (en) | 1998-02-09 | 1999-08-12 | Kaken Pharmaceutical Co., Ltd. | Oral preparations containing peptides promoting the secretion of growth hormone |
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| PT1077941E (pt) | 1998-05-11 | 2010-07-01 | Novo Nordisk As | Compostos com propriedades de libertaão da hormona de crescimento |
| EP1093463A1 (en) | 1998-06-09 | 2001-04-25 | Novo Nordisk A/S | A method for preparing a compound with growth hormone releasing properties |
| JP2002518328A (ja) | 1998-06-16 | 2002-06-25 | ファイザー・プロダクツ・インク | 筋骨格虚弱の治療用の（選択的）エストロゲン受容体モジュレーター（ｓｅｒｍ）および成長ホルモン分泌促進薬（ｇｈｓ）の治療的組合せ |
| HN1999000097A (es) | 1998-06-16 | 1999-11-03 | Pfizer Prod Inc | Terapia de combinacion para la fragilidad muscoloesqueletica |
| BRPI9911756B1 (pt) | 1998-06-30 | 2016-06-14 | Helsinn Healthcare Sa | composto, uso do mesmo, e composição farmaceutica |
| CA2340701C (en) | 1998-08-20 | 2009-05-26 | Sumitomo Pharmaceuticals Co., Ltd. | Oxindole derivatives as growth hormone releasers |
| US6358951B1 (en) | 1998-08-21 | 2002-03-19 | Pfizer Inc. | Growth hormone secretagogues |
| ATE304373T1 (de) * | 1999-12-28 | 2005-09-15 | Kaken Pharma Co Ltd | Nervenschutzmittel |
| CA2411667A1 (en) | 2000-05-30 | 2001-12-06 | Merck & Co. Inc. | Ghrelin analogs |
| ATE446758T1 (de) | 2000-05-31 | 2009-11-15 | Pfizer Prod Inc | Verwendung von wachstumshormonsekretagoga zur förderung der beweglichkeit des verdauungstrakts |
| AR029941A1 (es) | 2000-06-13 | 2003-07-23 | Zentaris Gmbh | Compuestos utiles para elevar el nivel plasmatico de la hormona del crecimiento y las composiciones farmaceuticas que las contienen |
| AU2001274601A1 (en) | 2000-06-23 | 2002-01-02 | Kaken Pharmaceutical Co., Ltd. | Preventives or remedies for heart failure |
| ITMI20011445A1 (it) | 2001-07-06 | 2003-01-06 | Europ Geie | Analoghi della cortistantina capaci di legarsi selettivamente ai recettori dei secretagoghi dell'ormone della crescita |
| CU23043A1 (es) | 2001-12-20 | 2005-05-20 | Ct Ingenieria Genetica Biotech | Composicion farmaceutica que contiene factor de crecimiento epidrmico (egf) para la prevencion de la amputacion de pie diabetico. |
| US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
| WO2005039625A1 (en) | 2003-10-28 | 2005-05-06 | Rheoscience A/S | Growth hormone secretagogue receptor agonists |
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-
2006
- 2006-02-28 CU CU20060050A patent/CU23558A1/es active IP Right Grant
-
2007
- 2007-02-27 AR ARP070100806A patent/AR059646A1/es not_active Application Discontinuation
- 2007-02-27 CL CL2007000528A patent/CL2007000528A1/es unknown
- 2007-02-28 RU RU2008138569/10A patent/RU2416618C2/ru not_active IP Right Cessation
- 2007-02-28 EP EP07711101.1A patent/EP1997827B1/en not_active Not-in-force
- 2007-02-28 AU AU2007219569A patent/AU2007219569B2/en not_active Ceased
- 2007-02-28 CN CN2007800153594A patent/CN101432294B/zh not_active Expired - Fee Related
- 2007-02-28 JP JP2008556643A patent/JP5183496B2/ja not_active Expired - Fee Related
- 2007-02-28 MX MX2008011142A patent/MX2008011142A/es active IP Right Grant
- 2007-02-28 CA CA2637593A patent/CA2637593C/en not_active Expired - Fee Related
- 2007-02-28 US US12/281,085 patent/US8367620B2/en not_active Expired - Fee Related
- 2007-02-28 WO PCT/CU2007/000007 patent/WO2007098716A1/es not_active Ceased
- 2007-02-28 MY MYPI20083178A patent/MY184130A/en unknown
- 2007-02-28 ES ES07711101.1T patent/ES2441441T3/es active Active
- 2007-02-28 BR BRPI0708366-1A patent/BRPI0708366A2/pt not_active IP Right Cessation
- 2007-02-28 KR KR1020087023543A patent/KR101409277B1/ko not_active Expired - Fee Related
-
2008
- 2008-08-19 ZA ZA200807162A patent/ZA200807162B/xx unknown
- 2008-09-29 NO NO20084118A patent/NO20084118L/no not_active Application Discontinuation
-
2016
- 2016-06-24 CL CL2016001648A patent/CL2016001648A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101432294B (zh) | 2013-09-11 |
| NO20084118L (no) | 2008-09-29 |
| WO2007098716A8 (es) | 2008-12-18 |
| AU2007219569B2 (en) | 2012-03-15 |
| RU2008138569A (ru) | 2010-04-10 |
| ES2441441T3 (es) | 2014-02-04 |
| EP1997827A1 (en) | 2008-12-03 |
| MX2008011142A (es) | 2008-09-08 |
| WO2007098716A1 (es) | 2007-09-07 |
| MY184130A (en) | 2021-03-19 |
| CN101432294A (zh) | 2009-05-13 |
| CL2016001648A1 (es) | 2017-02-24 |
| JP2009528303A (ja) | 2009-08-06 |
| RU2416618C2 (ru) | 2011-04-20 |
| AU2007219569A1 (en) | 2007-09-07 |
| US20100055118A1 (en) | 2010-03-04 |
| JP5183496B2 (ja) | 2013-04-17 |
| ZA200807162B (en) | 2009-06-24 |
| EP1997827B1 (en) | 2013-10-09 |
| CA2637593A1 (en) | 2007-09-07 |
| US8367620B2 (en) | 2013-02-05 |
| CU23558A1 (es) | 2010-07-20 |
| KR101409277B1 (ko) | 2014-06-24 |
| CA2637593C (en) | 2015-04-14 |
| KR20080110763A (ko) | 2008-12-19 |
| CL2007000528A1 (es) | 2008-01-18 |
| BRPI0708366A2 (pt) | 2011-05-24 |
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