AU2007219569B2 - Compounds analogous to growth hormone peptide secretagogues and preparations containing them - Google Patents
Compounds analogous to growth hormone peptide secretagogues and preparations containing themInfo
- Publication number
- AU2007219569B2 AU2007219569B2 AU2007219569A AU2007219569A AU2007219569B2 AU 2007219569 B2 AU2007219569 B2 AU 2007219569B2 AU 2007219569 A AU2007219569 A AU 2007219569A AU 2007219569 A AU2007219569 A AU 2007219569A AU 2007219569 B2 AU2007219569 B2 AU 2007219569B2
- Authority
- AU
- Australia
- Prior art keywords
- ghrelin
- ghs
- growth hormone
- receptor
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
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- Endocrinology (AREA)
- Diabetes (AREA)
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- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
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- Zoology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20060050A CU23558A1 (es) | 2006-02-28 | 2006-02-28 | Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento |
| CU2006-0050 | 2006-05-28 | ||
| PCT/CU2007/000007 WO2007098716A1 (es) | 2006-02-28 | 2007-02-28 | Compuestos analogos a los secretagogos peptidicos de la hormona de crecimiento y preparaciones que los contienen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2007219569A1 AU2007219569A1 (en) | 2007-09-07 |
| AU2007219569B2 true AU2007219569B2 (en) | 2012-03-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2007219569A Ceased AU2007219569B2 (en) | 2006-02-28 | 2007-02-28 | Compounds analogous to growth hormone peptide secretagogues and preparations containing them |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8367620B2 (https=) |
| EP (1) | EP1997827B1 (https=) |
| JP (1) | JP5183496B2 (https=) |
| KR (1) | KR101409277B1 (https=) |
| CN (1) | CN101432294B (https=) |
| AR (1) | AR059646A1 (https=) |
| AU (1) | AU2007219569B2 (https=) |
| BR (1) | BRPI0708366A2 (https=) |
| CA (1) | CA2637593C (https=) |
| CL (2) | CL2007000528A1 (https=) |
| CU (1) | CU23558A1 (https=) |
| ES (1) | ES2441441T3 (https=) |
| MX (1) | MX2008011142A (https=) |
| MY (1) | MY184130A (https=) |
| NO (1) | NO20084118L (https=) |
| RU (1) | RU2416618C2 (https=) |
| WO (1) | WO2007098716A1 (https=) |
| ZA (1) | ZA200807162B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP4831551B2 (ja) * | 2008-11-06 | 2011-12-07 | 国立大学法人名古屋大学 | 非虚血性心筋障害に対する医薬 |
| CU24473B1 (es) * | 2016-11-01 | 2020-02-04 | Centro De Ingenieria Genetica Y Biotecnologia Biocubafarma | Composición vacunal que comprende un péptido secretagogo de la hormona de crecimiento como adyuvante vacunal |
| RU2734835C1 (ru) * | 2020-02-11 | 2020-10-23 | Федеральное государственное бюджетное учреждение науки Лимнологический институт Сибирского отделение Российской академии наук (ЛИН СО РАН) | Способ повышения жизнестойкости эмбрионов рыб в аквакультуре |
Family Cites Families (92)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US3239345A (en) | 1965-02-15 | 1966-03-08 | Estrogenic compounds and animal growth promoters | |
| US4411890A (en) | 1981-04-14 | 1983-10-25 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
| US4036979A (en) | 1974-01-25 | 1977-07-19 | American Cyanamid Company | Compositions containing 4,5,6,7-tetrahydrobenz[b]thien-4-yl-ureas or derivatives and methods of enhancing growth rate |
| AU628322B2 (en) | 1988-01-28 | 1992-09-17 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
| DE68922602T2 (de) | 1988-01-28 | 1995-12-07 | Polygen Holding Corp | Polypeptide mit hormonwachstumsbefreiender wirkung. |
| JP2670680B2 (ja) | 1988-02-24 | 1997-10-29 | 株式会社ビーエムジー | 生理活性物質含有ポリ乳酸系微小球およびその製造法 |
| DK0554381T3 (da) | 1990-10-25 | 1996-04-09 | Genentech Inc | Anvendelse af beskyttende midler mod reaktive oxygenforbindelser |
| US5663146A (en) | 1991-08-22 | 1997-09-02 | Administrators Of The Tulane Educational Fund | Polypeptide analogues having growth hormone releasing activity |
| EP0669830A4 (en) | 1992-11-06 | 1997-02-26 | Merck & Co Inc | SUBSTITUTED DIPEPTIDE ANALOGS, WHICH SUPPORT THE RELEASE OF GROWTH HORMONE. |
| US5726319A (en) | 1992-11-06 | 1998-03-10 | Merck & Co., Inc. | Biphenyl substituted dipeptide analogs promote release of growth hormone |
| US5536716A (en) | 1992-12-11 | 1996-07-16 | Merck & Co., Inc. | Spiro piperidines and homologs which promote release of growth hormone |
| NZ258412A (en) | 1992-12-11 | 1997-01-29 | Merck & Co Inc | Spiro-fused piperidine derivatives and pharmaceutical compositions |
| HUT75224A (en) | 1993-10-19 | 1997-04-28 | Merck & Co Inc | Combination of bisphosphonates and growth hormone secretagogues |
| PL322706A1 (en) | 1993-11-09 | 1998-02-16 | Merck & Co Inc | Piperidines, pyrolidines and hexahydro-1h-azepins enhancing growth hormone liberation |
| US5494919A (en) | 1993-11-09 | 1996-02-27 | Merck & Co., Inc. | 2-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone |
| US5492916A (en) | 1993-12-23 | 1996-02-20 | Merck & Co., Inc. | Di- and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone |
| CA2176140A1 (en) | 1993-11-24 | 1995-06-01 | Meng Hsin Chen | Indolyl group containing compounds and the use thereof to promote the release of growth hormone(s) |
| US5721251A (en) | 1993-12-10 | 1998-02-24 | Merck & Co., Inc. | Piperidine, pyrrolidine and hexahydro-1H-azepines promote release of growth hormone |
| HU224345B1 (hu) | 1993-12-23 | 2005-08-29 | Novo Nordisk A/S. | Növekedési hormont felszabadító tulajdonságú peptidek, ezeket hatóanyagként tartalmazó gyógyszerkészítmények és alkalmazásuk |
| US5721250A (en) | 1993-12-23 | 1998-02-24 | Merck & Co. Inc. | Di-and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone |
| JP3759748B2 (ja) | 1993-12-23 | 2006-03-29 | ノボ ノルディスク アクティーゼルスカブ | 成長ホルモン放出性を有する化合物 |
| WO1995034311A1 (en) | 1994-06-13 | 1995-12-21 | Merck & Co., Inc. | Piperazine compounds promote release of growth hormone |
| US5783582A (en) | 1994-07-20 | 1998-07-21 | Merck & Co., Inc. | Piperidines and hexahydro-1H-azepines spiro substituted at the 4-position promote release of growth hormone |
| US5798337A (en) | 1994-11-16 | 1998-08-25 | Genentech, Inc. | Low molecular weight peptidomimetic growth hormone secretagogues |
| WO1996022996A1 (en) | 1995-01-25 | 1996-08-01 | Nippon Chemiphar Co., Ltd. | Dihydrophenazine derivatives |
| WO1996022997A1 (en) | 1995-01-27 | 1996-08-01 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
| AU4534696A (en) | 1995-02-09 | 1996-08-27 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
| WO1996024580A1 (en) | 1995-02-09 | 1996-08-15 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
| US5559128A (en) | 1995-04-18 | 1996-09-24 | Merck & Co., Inc. | 3-substituted piperidines promote release of growth hormone |
| EP0823904A4 (en) | 1995-04-19 | 1998-09-09 | Merck & Co Inc | Process for the preparation of spiroindolines |
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| ATE288444T1 (de) | 1995-05-29 | 2005-02-15 | Pfizer | Dipeptide, die die ausschüttung von wachstumshormonen stimulieren |
| BR9608909A (pt) | 1995-06-22 | 1999-03-02 | Novo Nordisk As | Composto composição farmacêutica processos para estimular a liberação do hormônio do crescimento da patuitária e aumentar a velocidade e extensão do crescimento dos animais para aumentar a produção de leite ou lã de animais ou para para doenças e uso do composto |
| WO1997007117A1 (en) | 1995-08-21 | 1997-02-27 | Eli Lilly And Company | 2-acylaminopropanamines as growth hormone secretagogues |
| CA2203428A1 (en) | 1995-08-21 | 1997-02-27 | Philip Arthur Hipskind | 2-acylaminopropanamides as growth hormone secretagogues |
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| US5767124A (en) | 1995-10-27 | 1998-06-16 | Merck & Co., Inc. | Polymorphic forms of a growth hormone secretagogue |
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| SK51198A3 (en) | 1995-10-27 | 1998-11-04 | Merck & Co Inc | Method for producing n-[1(r)-[(1,2-dihydro-1- -methanesulfonylspiro[3h-indole-3,4'-piperidine-1'-yl)carbonyl]- -2-(phenylmethyloxy)ethyl]-2-amino-2-methylpropanamide |
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| TW432073B (en) | 1995-12-28 | 2001-05-01 | Pfizer | Pyrazolopyridine compounds |
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| SE9601397D0 (sv) | 1996-04-12 | 1996-04-12 | Pharmacia Ab | Use of growth hormone |
| JP2000510453A (ja) | 1996-04-19 | 2000-08-15 | ノボ ノルディスク アクティーゼルスカブ | 成長ホルモン遊離特性を有する化合物 |
| WO1997040023A1 (en) | 1996-04-24 | 1997-10-30 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
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Also Published As
| Publication number | Publication date |
|---|---|
| CN101432294B (zh) | 2013-09-11 |
| NO20084118L (no) | 2008-09-29 |
| WO2007098716A8 (es) | 2008-12-18 |
| RU2008138569A (ru) | 2010-04-10 |
| ES2441441T3 (es) | 2014-02-04 |
| EP1997827A1 (en) | 2008-12-03 |
| MX2008011142A (es) | 2008-09-08 |
| WO2007098716A1 (es) | 2007-09-07 |
| MY184130A (en) | 2021-03-19 |
| CN101432294A (zh) | 2009-05-13 |
| CL2016001648A1 (es) | 2017-02-24 |
| JP2009528303A (ja) | 2009-08-06 |
| AR059646A1 (es) | 2008-04-16 |
| RU2416618C2 (ru) | 2011-04-20 |
| AU2007219569A1 (en) | 2007-09-07 |
| US20100055118A1 (en) | 2010-03-04 |
| JP5183496B2 (ja) | 2013-04-17 |
| ZA200807162B (en) | 2009-06-24 |
| EP1997827B1 (en) | 2013-10-09 |
| CA2637593A1 (en) | 2007-09-07 |
| US8367620B2 (en) | 2013-02-05 |
| CU23558A1 (es) | 2010-07-20 |
| KR101409277B1 (ko) | 2014-06-24 |
| CA2637593C (en) | 2015-04-14 |
| KR20080110763A (ko) | 2008-12-19 |
| CL2007000528A1 (es) | 2008-01-18 |
| BRPI0708366A2 (pt) | 2011-05-24 |
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