MX372859B - Aparatos y métodos para inyección ocular. - Google Patents

Aparatos y métodos para inyección ocular.

Info

Publication number
MX372859B
MX372859B MX2015015282A MX2015015282A MX372859B MX 372859 B MX372859 B MX 372859B MX 2015015282 A MX2015015282 A MX 2015015282A MX 2015015282 A MX2015015282 A MX 2015015282A MX 372859 B MX372859 B MX 372859B
Authority
MX
Mexico
Prior art keywords
medicament container
actuation rod
needle
disposed
end portion
Prior art date
Application number
MX2015015282A
Other languages
English (en)
Spanish (es)
Other versions
MX2015015282A (es
Inventor
Andrew Kent Bauer
Christopher John Brooks
David Jackson Trettin
Jesse Yoo
Justin William Arsenault
Rafael Victor Andino
Stephanie Elaine Lewis
Trent John Kahuate
Vladimir Zarnitsyn
Original Assignee
Clearside Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51844124&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX372859(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Clearside Biomedical Inc filed Critical Clearside Biomedical Inc
Publication of MX2015015282A publication Critical patent/MX2015015282A/es
Publication of MX372859B publication Critical patent/MX372859B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2055—Connecting means having gripping means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3293—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle hub
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M5/344—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub using additional parts, e.g. clamping rings or collets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M5/346—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub friction fit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M5/347—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub rotatable, e.g. bayonet or screw
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M5/348—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub snap lock, i.e. upon axial displacement of needle assembly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M5/349—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub using adhesive bond or glues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
    • A61M5/482—Varying injection pressure, e.g. by varying speed of injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
    • A61M5/484—Regulating injection pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0004—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable
    • A61F2250/0007—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable for adjusting length
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0069—Sealing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508—Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0612—Eyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
MX2015015282A 2013-05-03 2014-05-02 Aparatos y métodos para inyección ocular. MX372859B (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201361819052P 2013-05-03 2013-05-03
US201361819048P 2013-05-03 2013-05-03
US201361827371P 2013-05-24 2013-05-24
US201461944214P 2014-02-25 2014-02-25
US201461953147P 2014-03-14 2014-03-14
PCT/US2014/036590 WO2014179698A2 (en) 2013-05-03 2014-05-02 Apparatus and methods for ocular injection

Publications (2)

Publication Number Publication Date
MX2015015282A MX2015015282A (es) 2016-02-26
MX372859B true MX372859B (es) 2020-07-07

Family

ID=51844124

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015015282A MX372859B (es) 2013-05-03 2014-05-02 Aparatos y métodos para inyección ocular.
MX2020006004A MX2020006004A (es) 2013-05-03 2015-11-03 Aparatos y metodos para inyeccion ocular.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2020006004A MX2020006004A (es) 2013-05-03 2015-11-03 Aparatos y metodos para inyeccion ocular.

Country Status (13)

Country Link
US (11) US9539139B2 (https=)
EP (3) EP4378444A3 (https=)
JP (3) JP6379183B2 (https=)
KR (2) KR102406619B1 (https=)
CN (3) CN116327482A (https=)
AU (1) AU2014259694B2 (https=)
BR (1) BR112015027762A2 (https=)
CA (2) CA3121759C (https=)
EA (1) EA032039B1 (https=)
IL (2) IL242395B (https=)
MX (2) MX372859B (https=)
SG (2) SG10201702674PA (https=)
WO (1) WO2014179698A2 (https=)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US7909789B2 (en) 2006-06-26 2011-03-22 Sight Sciences, Inc. Intraocular implants and methods and kits therefor
US8529622B2 (en) 2010-02-05 2013-09-10 Sight Sciences, Inc. Intraocular implants and related kits and methods
JP5996544B2 (ja) 2010-10-15 2016-09-21 クリアサイド・バイオメディカル・インコーポレーテッドＣｌｅａｒｓｉｄｅ Ｂｉｏｍｅｄｉｃａｌ Ｉｎｃｏｒｐｏｒａｔｅｄ 眼球アクセス用装置
ES2961369T3 (es) 2012-03-20 2024-03-11 Sight Sciences Inc Sistemas de entrega ocular
MX373894B (es) 2012-11-08 2020-07-09 Clearside Biomedical Inc Métodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos.
BR112015027762A2 (pt) 2013-05-03 2017-08-29 Clearside Biomedical Inc Aparelho e métodos para injeção ocular
WO2014197317A1 (en) 2013-06-03 2014-12-11 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using multiple reservoirs
US10010447B2 (en) 2013-12-18 2018-07-03 Novartis Ag Systems and methods for subretinal delivery of therapeutic agents
WO2015141432A1 (ja) * 2014-03-17 2015-09-24 国立大学法人大阪大学 治療器具
EP3157598A4 (en) 2014-06-20 2018-05-16 Clearside Biomedical, Inc. Variable diameter cannula and methods for controlling insertion depth for medicament delivery
CN107249522B (zh) 2014-09-19 2021-04-20 奥叙拉尔有限公司 眼科递送装置
WO2016042163A2 (en) * 2014-09-19 2016-03-24 Medterials, Inc. Ophthalmic drug compositions
USD750223S1 (en) 2014-10-14 2016-02-23 Clearside Biomedical, Inc. Medical injector for ocular injection
US20160106587A1 (en) * 2014-10-16 2016-04-21 Incept, Llc Ocular gels or hydrogels and microinjectors
US20170304115A1 (en) * 2014-11-11 2017-10-26 Eyevation, Llc Delivery device
US11071643B2 (en) * 2014-11-28 2021-07-27 Visionisti Oy Ocular therapeutics tool
US9411111B2 (en) * 2014-12-09 2016-08-09 Sae Magnetics (H.K.) Ltd. Pluggable optical connector, lock and release mechanism therefor
US10299958B2 (en) 2015-03-31 2019-05-28 Sight Sciences, Inc. Ocular delivery systems and methods
KR20260025887A (ko) * 2015-06-06 2026-02-24 클라우드브레이크 테라퓨틱스, 엘엘씨 익상편을 치료하기 위한 조성물 및 방법
US11154420B2 (en) 2015-09-17 2021-10-26 Oxular Limited Ophthalmic injection device
US10390901B2 (en) 2016-02-10 2019-08-27 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
US11268607B1 (en) 2016-02-17 2022-03-08 Helix Linear Technologies Lead screw nuts having threads formed from different materials
WO2017158365A2 (en) * 2016-03-16 2017-09-21 Oxular Limited Ophthalmic delivery device and ophthalmic active agent containing compositions
ES2780381T3 (es) * 2016-04-06 2020-08-25 Clinica De Ortodoncia Y Cirugia Maxilofacial Sl Marcador quirúrgico
EP3452165A1 (en) 2016-05-02 2019-03-13 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
AU2017274195B2 (en) 2016-06-02 2022-04-07 Ads Therapeutics Llc Compositions and methods of using nintedanib for improving glaucoma surgery success
US10806629B2 (en) * 2016-06-17 2020-10-20 Gyroscope Therapeutics Limited Injection device for subretinal delivery of therapeutic agent
CN106038053B (zh) * 2016-07-05 2018-11-20 颜繁诚 眼球后注药装置
IL305537B2 (en) * 2016-08-12 2025-02-01 Clearside Biomedical Inc Devices and methods for adjusting the insertion depth of a needle for administering a drug
US20180092776A1 (en) 2016-09-30 2018-04-05 Sara Heikali Method and device for treating and managing diseased ocular tissue
CN106725852A (zh) * 2016-12-02 2017-05-31 上海精劢医疗科技有限公司 肺部穿刺的手术导航系统
EP3554435B1 (en) * 2016-12-15 2025-06-04 Clearside Biomedical, Inc. Systems for delivering drugs to retinal tissue
EP3554582A4 (en) * 2016-12-16 2020-06-24 The Brigham and Women's Hospital, Inc. System and method for resistance-dependent, self-regulated medical penetration
JP7153650B2 (ja) 2016-12-19 2022-10-14 ニュー ワールド メディカル インコーポレイテッド 眼球治療装置、及び関連する使用方法
USD1016599S1 (en) 2017-02-17 2024-03-05 Helix Linear Technologies Nut
WO2018167103A1 (en) * 2017-03-13 2018-09-20 Genfit Pharmaceutical compositions for combination therapy
US12090294B2 (en) 2017-05-02 2024-09-17 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
EP3681471B1 (en) * 2017-09-15 2025-03-05 Oxular Limited Ophthalmic delivery device
CN107561233B (zh) * 2017-09-25 2023-11-10 中国标准化研究院 一种禽蛋新鲜度检测装置
WO2019089573A1 (en) * 2017-10-30 2019-05-09 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Treatment of ocular conditions utilizing a histone/protein deacetylase inhibitor
EP3488819A1 (en) * 2017-11-24 2019-05-29 Chandrashekar Balachandran Delivery system
EP3717024B8 (en) 2017-11-29 2025-10-29 Copernicus Therapeutics, Inc. Gene therapy for ocular improvement
CA3096847A1 (en) * 2018-04-09 2019-10-17 Sio2 Medical Products, Inc. Stretchable plunger assemblies
CN112312868B (zh) 2018-04-12 2023-12-22 新世界医学有限公司 用于眼内流体注射的装置和方法
FR3080289B1 (fr) * 2018-04-18 2021-10-29 Nemera La Verpilliere Dispositif d'injection d'implant dote de moyens de retenue par friction
KR102709338B1 (ko) 2018-08-06 2024-09-25 이태이 초워스 안구 내 주사를 위한 멀티-루멘 주사기
CN109402127B (zh) * 2018-09-29 2021-12-10 复旦大学附属眼耳鼻喉科医院 一组与结缔组织生长因子特异性结合的高亲和力核酸适配体及其应用
CN117159272A (zh) * 2018-10-24 2023-12-05 新世界医学有限公司 眼科装置和用于该眼科装置的内部机构
US10722397B2 (en) 2018-10-24 2020-07-28 New World Medical, Inc. Ophthalmic device
CN109431679B (zh) * 2018-12-06 2024-02-06 苏州理想眼科医院有限公司 一种眼内精密器械无摩擦手柄
US11957569B2 (en) 2019-02-28 2024-04-16 Tissuecor, Llc Graft tissue injector
CA3136814A1 (en) 2019-04-16 2020-10-22 Clearside Biomedical, Inc. Injectable triamcinolone formulations
CN109999279B (zh) * 2019-05-05 2021-04-20 河南省中医院（河南中医药大学第二附属医院） 一种麻醉科用进针装置
WO2020227341A1 (en) 2019-05-06 2020-11-12 9 Meters Biopharma, Inc. Compositions and methods for treating sjogren's syndrome
CN110101423B (zh) * 2019-05-09 2021-07-13 吉林大学中日联谊医院 一种血管外科动静脉手术止血装置
EP3886946A1 (en) 2019-06-05 2021-10-06 Regeneron Pharmaceuticals, Inc. Devices and methods for precision dose delivery
WO2020251960A1 (en) 2019-06-09 2020-12-17 Banov Jacob Device and system for remote regulation and monitoring of drug delivery and method of same
EP3753601B1 (en) 2019-06-21 2024-09-18 Samia Trigo Arbache Needle improvements for drug delivery using tattoo machines
BR112022005148A2 (pt) * 2019-09-20 2023-02-23 Meiragtx Therapeutics Inc Sistemas de injeção e métodos de uso dos mesmos
WO2021113041A1 (en) 2019-12-03 2021-06-10 University Of Florida Research Foundation Devices and methods for intravitreal injection of substances
WO2021123953A1 (en) * 2019-12-19 2021-06-24 Janssen Biotech, Inc. Injection pump needle mechanics
KR102222519B1 (ko) * 2019-12-31 2021-03-04 주식회사 이노테라피 자기실링이 가능한 안구의 누공억제용 주사바늘 및 그 제조방법
IT202000001810A1 (it) * 2020-01-30 2021-07-30 Alletti Salvatore Gueli Dispositivo medico per l'iniezione di fluidi
CN115955951B (zh) * 2020-06-11 2026-03-24 亚斯库拉科技公司 用于跨各种材料特性的受控注射的装置
EP4196060A1 (en) * 2020-08-12 2023-06-21 Regeneron Pharmaceuticals, Inc. Systems and methods for drug delivery to ocular tissue
IL300504A (en) * 2020-08-13 2023-04-01 Meiragtx Uk Ii Ltd Motorized injection system and methods of use
EP4225235A4 (en) * 2020-10-09 2024-08-14 Clearside Biomedical, Inc. DEVICE AND METHOD FOR RETINAL INJECTION
US20230363941A1 (en) * 2020-10-09 2023-11-16 Clearside Biomedical, Inc. Apparatus and methods of retinal injection
CN112603646A (zh) * 2020-12-21 2021-04-06 上海昶衡生物科技有限公司 一种脉络膜上腔注射器
EP4043049B1 (en) 2021-02-15 2025-04-02 SHL Medical AG An assembly for a medicament delivery device
AU2022257597A1 (en) * 2021-04-16 2023-09-28 Alcon Inc. Implant delivery device
CN115337140B (zh) * 2021-05-13 2025-01-10 中国医学科学院北京协和医院 眼部植入器具总成
CN115337139B (zh) * 2021-05-13 2025-02-25 中国医学科学院北京协和医院 眼部穿刺装置和眼部植入器具总成
WO2022236778A1 (en) 2021-05-13 2022-11-17 Beijing Sightnovo Medical Technology Co., Ltd Medical penetration device and system
WO2022236779A1 (en) 2021-05-13 2022-11-17 Beijing Sightnovo Medical Technology Co., Ltd Medical penetration and drainage for glaucoma treatment
IL309970A (en) * 2021-07-22 2024-03-01 Chengdu Origen Biotechnology Co Ltd Eye injection assembly, injection device and method of using it
US11984211B2 (en) 2021-08-30 2024-05-14 Isaac Abadi System and method for utilization of data from remote regulation and monitoring of drug delivery
US12090262B2 (en) 2021-09-01 2024-09-17 Tissuecor, Llc Device and system for injecting biological tissue
NL2029490B1 (en) * 2021-10-22 2023-05-19 Life Science Methods B V Microinjection system and method
USD1037439S1 (en) 2022-01-17 2024-07-30 EyePoint Pharamaceuticals, Inc. Ocular injector
GB202200706D0 (en) * 2022-01-20 2022-03-09 Cambridge Univ Hospitals Nhs Foundation Trust A surgical instrument
CA3265748A1 (en) * 2022-08-23 2024-02-29 Sight Sciences, Inc. OCULAR PLACEMENT SYSTEMS AND METHODS
IL320780A (en) * 2022-11-11 2025-07-01 Beijing Sightnovo Medical Tech Co Ltd Drug-containing devices, suprachoroidal space implants, and injection adapters
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
EP4480517A1 (de) 2023-06-20 2024-12-25 Ypsomed AG Autoinjektor zur intravitrealen injektion
WO2025071724A1 (en) * 2023-09-27 2025-04-03 West Pharmaceutical Services, Inc. Precision needle advancement
TW202539597A (zh) * 2023-11-08 2025-10-16 美商再生元醫藥公司 用於眼部組織之藥物遞送的系統及方法
KR102763993B1 (ko) * 2023-12-27 2025-02-11 서울대학교병원 공막 마커 및 이를 포함하는 마킹 장치
GB2632891B (en) * 2024-01-30 2025-09-03 Alwitry Amar Cannula safety sleeve invention
WO2025169089A1 (en) 2024-02-05 2025-08-14 Sun Pharmaceutical Industries Limited Ophthalmic compositions of tyrosine kinase inhibitors and their uses
WO2025217214A2 (en) 2024-04-08 2025-10-16 Regenxbio Inc. Recombinant adeno-associated viruses and uses thereof
TW202548025A (zh) 2024-04-08 2025-12-16 美商銳進科斯生物股份有限公司 載體化抗補體抗體與補體劑及其投與

Family Cites Families (582)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2187259A (en) 1936-07-11 1940-01-16 George E Barnhart Hypodermic needle
US2841145A (en) 1956-05-07 1958-07-01 John A Epps Syringe
US2939459A (en) 1957-01-11 1960-06-07 Jorge A Lazarte Tandem syringe
US3477432A (en) 1964-07-21 1969-11-11 Joseph Denman Shaw Combination mixing and injecting medical syringe
US3376999A (en) 1967-05-31 1968-04-09 Gen Dynamics Corp Packaging, mixing and dispensing apparatus
US3892311A (en) 1969-01-31 1975-07-01 Vincent R Sneider Disposable syringe kit
AT318132B (de) 1969-08-01 1974-09-25 Dentaire Ivoclar Ets Mischbehälter für die Aufnahme von miteinander reagierenden Substanzen für die Herstellung von gebrauchsfertigen pastenförmigen Dentalpräparaten
US3762540A (en) 1970-05-19 1973-10-02 Dentaire Ivoclar Ets Receptacle having at least three chambers
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3838690A (en) 1971-07-14 1974-10-01 B Friedman Replaceable cartridge hypodermic syringe having sterile maintenance of needle
US3788320A (en) 1972-02-25 1974-01-29 Kendall & Co Spinal needle
US3962430A (en) 1974-08-07 1976-06-08 Merck & Co., Inc. Sterilization of solid non-electrolyte medicinal agents employing sodium chloride
US4230112A (en) 1978-08-07 1980-10-28 Smith Philip E Syringe-type liquid container dispenser adapter
US4303071A (en) 1978-08-07 1981-12-01 Baxa Corporation Syringe-type liquid container dispenser adapter
US4226328A (en) 1979-04-09 1980-10-07 Baxter Travenol Laboratories, Inc. Catheterization package
US4383530A (en) 1981-06-05 1983-05-17 John Bruno Hypodermic needle and method of making needles
US4377897A (en) 1981-08-04 1983-03-29 Ocular Associates Ophthalmic needle and method for manufacturing the same
US4432964A (en) 1981-08-24 1984-02-21 Alza Corporation Topical composition containing steroid in two forms released independently from polymeric carrier
JPS5828535B2 (ja) 1981-09-22 1983-06-16 茨城県 測温用センサ−
US4525346A (en) 1981-09-28 1985-06-25 Alcon Laboratories, Inc. Aqueous antimicrobial ophthalmic solutions
JPS5875563A (ja) 1981-10-30 1983-05-07 テルモ株式会社 留置カテ−テル用接続具
US4564016A (en) 1982-05-24 1986-01-14 The Board Of Trustees Of The Leland Stanford Junior University Apparatus for introducing ionized drugs into the posterior segment of the eye and method
DE3465696D1 (en) 1983-06-28 1987-10-08 Sterimed Gmbh Medical apparatus with insertion aid device
US4573993A (en) 1983-09-29 1986-03-04 Instafil, Inc. Fluid transfer apparatus
US4501363A (en) 1983-10-25 1985-02-26 Isbey Jr Edward K Surgical kit
NZ212899A (en) * 1984-07-31 1987-10-30 Phillips Pty Ltd N J Piston operated adjustable volume dose injector for animals
US4708147A (en) 1985-02-25 1987-11-24 Haaga John R Universal biopsy needle
US4826871A (en) 1985-03-13 1989-05-02 Gressel Philip D Topical ophthalmic compositions containing one or more retinoids
US4689040A (en) 1985-04-29 1987-08-25 Thompson Robert J Tip for a phacoemulsification needle
US4689042A (en) 1985-05-20 1987-08-25 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
US4826490A (en) 1985-07-29 1989-05-02 National Research Development Corporation Safety device for hypodermic needle or the like
US4601708A (en) 1985-09-09 1986-07-22 Pavel Jordan Automatic injection for syringe needle, and assembly
US4662878A (en) 1985-11-13 1987-05-05 Patents Unlimited Ltd. Medicine vial adaptor for needleless injector
US5023087A (en) 1986-02-10 1991-06-11 Liposome Technology, Inc. Efficient method for preparation of prolonged release liposome-based drug delivery system
US4627841A (en) 1986-02-18 1986-12-09 Dorr Robert T Infusion needle
US4736850A (en) 1986-10-17 1988-04-12 W. L. Gore & Associates, Inc. Endothelial cell harvesting kit
US4966773A (en) 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
US4795432A (en) 1987-02-19 1989-01-03 Karczmer Claude M Shield assembly for hypodermic injection devices
US4804371A (en) 1987-05-06 1989-02-14 Vaillancourt Vincent L Post-injection needle sheath
ES2050000T3 (es) 1987-07-10 1994-05-01 Braun Melsungen Ag Canula.
DE3802158A1 (de) 1987-08-11 1989-02-23 Hoechst Ag Vorrichtung zur applikation von implantaten
US5547467A (en) 1988-01-21 1996-08-20 Massachusettes Institute Of Technology Method for rapid temporal control of molecular transport across tissue
US5211638A (en) 1988-01-25 1993-05-18 Baxter International Inc. Pre-slit injection site
US5100394A (en) 1988-01-25 1992-03-31 Baxter International Inc. Pre-slit injection site
US5066276A (en) 1988-06-21 1991-11-19 Alcon Laboratories, Inc. Method and apparatus for injecting viscous fluid into the eye to lift pre-retinal and post-retinal membrane with linear pressure control
CA1335335C (en) 1988-09-23 1995-04-25 Frank Hunter Oral hygiene
CA2001444C (en) 1988-10-28 2000-07-25 Darrel F. Untereker Iontophoresis electrode
US5057072A (en) 1988-10-28 1991-10-15 Medtronic, Inc. Iontophoresis electrode
US5817075A (en) 1989-08-14 1998-10-06 Photogenesis, Inc. Method for preparation and transplantation of planar implants and surgical instrument therefor
US5164188A (en) 1989-11-22 1992-11-17 Visionex, Inc. Biodegradable ocular implants
US5025811A (en) 1990-02-16 1991-06-25 Dobrogowski Michael J Method for focal destruction of eye tissue by electroablation
US5024662A (en) * 1990-03-13 1991-06-18 Menes Cesar M Resistance syringe for epidural anesthesia
US5015240A (en) 1990-05-01 1991-05-14 Ian Campbell Cree Hypodermic needle shield
US5098389A (en) 1990-06-28 1992-03-24 Becton, Dickinson And Company Hypodermic needle assembly
ES2023597A6 (es) 1990-11-05 1992-01-16 Rodiera Olive Jose Javier Aguja para uso medico, en especial para funcion lumbar y anestesia regional.
US5273530A (en) 1990-11-14 1993-12-28 The University Of Rochester Intraretinal delivery and withdrawal instruments
US5292310A (en) 1990-12-27 1994-03-08 Inbae Yoon Safety needle
US5295974A (en) 1991-01-07 1994-03-22 Laughlin D Michael O Shielded hypodermic needle with I.V. cannula
EP0501034A1 (en) 1991-01-30 1992-09-02 CeramOptec GmbH Illuminated leading probe device
GB9103291D0 (en) 1991-02-15 1991-04-03 Waverley Pharma Ltd Transfer adaptor
US5137509A (en) 1991-04-17 1992-08-11 Dexide, Inc. Surgical insufflation instrument
US5206267A (en) 1991-05-09 1993-04-27 Morton Shulman Pain controlling composition and method of preparation
US5181909A (en) 1991-05-15 1993-01-26 Mcfarlane Richard H Ampule-container medical syringe and methods
GB9111049D0 (en) 1991-05-22 1991-07-17 Parkin Adrian Hypodermic needle
DE4120173A1 (de) 1991-06-19 1992-12-24 Hoechst Ag Positiv arbeitendes strahlungsempfindliches gemisch und damit hergestelltes strahlungsempfindliches aufzeichnungsmaterial
US5312361A (en) 1991-09-13 1994-05-17 Zadini Filiberto P Automatic cannulation device
US5172807A (en) 1991-09-30 1992-12-22 Centrix, Inc. Cement mixing capsule
AU4282793A (en) 1992-04-10 1993-11-18 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University A microneedle for injection of ocular blood vessels
JPH08502033A (ja) 1992-07-08 1996-03-05 セルトリックス ファーマシューティカルズ，インコーポレイテッド ＴＧＦ−βを用いる眼疾患の治療方法
US5767079A (en) 1992-07-08 1998-06-16 Celtrix Pharmaceuticals, Inc. Method of treating ophthalmic disorders using TGF -β
US5295972A (en) 1992-08-04 1994-03-22 Metatech Corporation Hypodermic syringe with protective cap
US5279564A (en) 1992-09-11 1994-01-18 Edward Weck Incorporated Cannula retention device
US5300084A (en) 1992-11-23 1994-04-05 United States Surgical Corporation Pneumoperitoneum needle
EP0674528A4 (en) 1992-12-02 1996-06-26 Insite Vision Inc DRUG DELIVERY SYSTEM BASED ON CYCLODEXTRIN AND A POLYMER.
US5320609A (en) 1992-12-07 1994-06-14 Habley Medical Technology Corporation Automatic pharmaceutical dispensing syringe
US5681825A (en) 1993-03-15 1997-10-28 Lindqvist; Bengt Surgical method
US5399159A (en) 1993-03-30 1995-03-21 Origin Medsystems, Inc. Apparatus and method for hand-held insufflation
US5358489A (en) 1993-05-27 1994-10-25 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5407070A (en) 1993-08-18 1995-04-18 Bascos; Christine M. One-time resealable package for needled medical devices
US5415629A (en) 1993-09-15 1995-05-16 Henley; Julian L. Programmable apparatus for the transdermal delivery of drugs and method
US5443505A (en) 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
US5354286A (en) 1993-12-07 1994-10-11 Survival Technology, Inc. Injection device having polyparaxylylene coated container
US5397313A (en) 1994-01-27 1995-03-14 The Kendall Company Low friction syringe
US5527306A (en) 1994-04-18 1996-06-18 Haining; Michael L. Vial adapter
US5658256A (en) 1994-08-22 1997-08-19 Shields; Jack W. Universal sharps shield
SE9402816D0 (sv) 1994-08-24 1994-08-24 Pharmacia Ab Method and meams for drug administration
AU3584895A (en) 1994-09-28 1996-04-19 Celtrix Pharmaceuticals, Inc. Method of treating macular degeneration using tgf-beta
US5792099A (en) 1995-02-14 1998-08-11 Decamp; Dennis Syringe and cannula for insertion of viscoelastic material into an eye and method of using same
IL114960A0 (en) 1995-03-20 1995-12-08 Medimop Medical Projects Ltd Flow control device
US5779668A (en) 1995-03-29 1998-07-14 Abbott Laboratories Syringe barrel for lyophilization, reconstitution and administration
US5575780A (en) 1995-04-28 1996-11-19 Saito; Yoshikuni Medical hollow needle and a method of producing thereof
US5968022A (en) 1995-04-28 1999-10-19 Saito; Yoshikuni Medical hollow needle and method of production
US5839715A (en) 1995-05-16 1998-11-24 Alaris Medical Systems, Inc. Medical adapter having needleless valve and sharpened cannula
USD383049S (en) 1995-06-30 1997-09-02 Fiskars Inc. Tool handle grip
US6280470B1 (en) 1995-10-20 2001-08-28 Gholam A. Peyman Intrastromal corneal modification
US6039093A (en) 1995-10-20 2000-03-21 Schering Aktiengesellschaft Adapter for extracting a liquid from a container closed with a stopper
WO1997025015A1 (en) 1996-01-11 1997-07-17 Duoject Medical Systems Inc. Delivery system for pharmaceuticals packed in pharmaceutical vials
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
US5766198A (en) 1996-06-10 1998-06-16 Li; Bing Surgical knife employing a vacuum to ensure precise depth of incisions
US5752942A (en) 1996-06-20 1998-05-19 Becton Dickinson And Company Five beveled point geometry for a hypodermic needle
US5788679A (en) 1996-06-26 1998-08-04 Gravlee, Jr.; Joseph F. Phacoemulsification needle
US5976573A (en) 1996-07-03 1999-11-02 Rorer Pharmaceutical Products Inc. Aqueous-based pharmaceutical composition
US5911223A (en) 1996-08-09 1999-06-15 Massachusetts Institute Of Technology Introduction of modifying agents into skin by electroporation
US5951520A (en) 1996-12-19 1999-09-14 Bio-Plexus, Inc. Self-blunting needle medical devices and methods of manufacture thereof
GB9701413D0 (en) 1997-01-24 1997-03-12 Smithkline Beecham Biolog Novel device
US5919158A (en) 1997-02-13 1999-07-06 Emory University Method and apparatus for preventing and clearing condensation on the lens during a fluid-gas exchange portion of a pars plana vitrectomy
US20050096282A1 (en) * 1997-04-21 2005-05-05 Lewin Alfred S. Adeno-associated virus-delivered ribozyme compositions and methods for the treatment of retinal diseases
YU58599A (sh) 1997-05-16 2000-12-28 Amgen Inc. Gelovi sa usporenim podržanim oslobađanjem
AUPO940697A0 (en) 1997-09-23 1997-10-16 Kaal, Joseph Hermes Retractable syringe
FR2773320B1 (fr) 1998-01-05 2000-03-03 Optisinvest Dispositif pour le transfert intraoculaire de produits actifs par iontophorese
EP1053041A4 (en) 1998-01-12 2001-02-07 Georgia Tech Res Inst ASSESSMENT AND CONTROL OF ACOUSTIC EFFECTS ON TISSUE
US6003566A (en) 1998-02-26 1999-12-21 Becton Dickinson And Company Vial transferset and method
US6059111A (en) 1998-03-04 2000-05-09 Medtronic, Inc. Medical device packaging system
US6309347B1 (en) 1998-03-17 2001-10-30 Fuji Photo Optical Co., Ltd. Air and water supply system for endoscopes
JP2951938B1 (ja) 1998-03-19 1999-09-20 日本ケミカルリサーチ株式会社 薬剤溶解機構を内蔵した注射器
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6378714B1 (en) 1998-04-20 2002-04-30 Becton Dickinson And Company Transferset for vials and other medical containers
US6209738B1 (en) 1998-04-20 2001-04-03 Becton, Dickinson And Company Transfer set for vials and medical containers
US6957745B2 (en) 1998-04-20 2005-10-25 Becton, Dickinson And Company Transfer set
US6540725B1 (en) 1998-06-04 2003-04-01 Biosense Webster, Inc. Injection catheter with controllably extendable injection needle
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6936053B1 (en) 1998-07-02 2005-08-30 Jeffrey N. Weiss Ocular implant needle
US6378526B1 (en) 1998-08-03 2002-04-30 Insite Vision, Incorporated Methods of ophthalmic administration
US6309374B1 (en) 1998-08-03 2001-10-30 Insite Vision Incorporated Injection apparatus and method of using same
FR2784034B1 (fr) 1998-10-01 2000-12-15 Marc Brunel Dispositif d'injection a usage unique destine a etre pre-rempli
US6219575B1 (en) 1998-10-23 2001-04-17 Babak Nemati Method and apparatus to enhance optical transparency of biological tissues
US20040141925A1 (en) 1998-11-12 2004-07-22 Elan Pharma International Ltd. Novel triamcinolone compositions
US6670321B1 (en) 1998-12-30 2003-12-30 The Children's Medical Center Corporation Prevention and treatment for retinal ischemia and edema
WO2000040262A1 (en) 1999-01-05 2000-07-13 The Flinders University Of South Australia Novel agents and methods for treatment and diagnosis of ocular disorders
JP3492543B2 (ja) 1999-03-15 2004-02-03 金子工業有限会社 注射針とその製造方法
DE19916979A1 (de) 1999-04-15 2000-11-02 Sican Gmbh Verfahren zur Füllstandsmessung und Füllstandssensor
EP1211184B1 (en) 1999-04-20 2010-01-20 JMS Co., Ltd. Cap for container and adaptor for liquid communication
US6699210B2 (en) 1999-04-27 2004-03-02 The Arizona Board Of Regents Glaucoma shunt and a method of making and surgically implanting the same
US6159218A (en) 1999-05-19 2000-12-12 Aramant; Robert B. Retinal tissue implantation tool
US6319240B1 (en) 1999-05-25 2001-11-20 Iomed, Inc. Methods and apparatus for ocular iontophoresis
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
FR2794650B1 (fr) 1999-06-10 2001-09-14 Marc Brunel Dispositif d'injection a usage unique
US6738526B1 (en) 1999-07-30 2004-05-18 Microsoft Corporation Method and apparatus for filtering and caching data representing images
CA2382021A1 (en) 1999-09-03 2001-03-15 Pharmaspec Corporation Multi-cannula catheter for administering therapy to disparate points in a vessel in which fluid flow past the catheter is precluded
US6569123B2 (en) 1999-10-14 2003-05-27 Becton, Dickinson And Company Prefillable intradermal injector
US6494865B1 (en) 1999-10-14 2002-12-17 Becton Dickinson And Company Intradermal delivery device including a needle assembly
JP2003511204A (ja) 1999-10-21 2003-03-25 アルコン，インコーポレイティド テノン下薬剤送出
FR2801795B1 (fr) 1999-12-07 2002-07-05 Plastef Investissements Dispositif de support de securite pour une seringue et ensemble d'un tel dispositif et d'une seringue
KR100769224B1 (ko) 1999-12-10 2007-10-22 아이싸이언스 인터벤셔날 코포레이션 안 질환의 치료방법
US20010051798A1 (en) 1999-12-28 2001-12-13 Hochman Mark N. Method of performing an injection using a bi-directional rotational insertion technique
US6726676B2 (en) 2000-01-05 2004-04-27 Grieshaber & Co. Ag Schaffhausen Method of and device for improving the flow of aqueous humor within the eye
US6139534A (en) 2000-01-24 2000-10-31 Bracco Diagnostics, Inc. Vial access adapter
US6544246B1 (en) 2000-01-24 2003-04-08 Bracco Diagnostics, Inc. Vial access adapter and vial combination
US6832994B2 (en) 2000-01-24 2004-12-21 Bracco Diagnostics Inc. Table top drug dispensing vial access adapter
US6503240B1 (en) 2000-01-24 2003-01-07 Brocco Diagnostics, Inc. Vial access adapter
US7799009B2 (en) 2000-01-24 2010-09-21 Bracco Diagnostics Inc. Tabletop drug dispensing vial access adapter
RU14351U1 (ru) 2000-02-15 2000-07-20 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" Игла-направитель для пункции ретробульбарного пространства
US6558361B1 (en) 2000-03-09 2003-05-06 Nanopass Ltd. Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems
IL134997A0 (en) 2000-03-09 2001-05-20 Yehoshua Yeshurun Health care system based on micro device
JP4372310B2 (ja) 2000-04-10 2009-11-25 ニプロ株式会社 混注用アダプター
US6622864B1 (en) 2000-06-01 2003-09-23 Osteotech, Inc. Moisture resistant package for storing sterile items
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US6530904B1 (en) 2000-08-15 2003-03-11 Evan T. Edwards Medical injector
JP4187922B2 (ja) 2000-09-14 2008-11-26 テルモ株式会社 液体注入針および液体注入装置
US6546283B1 (en) 2000-10-18 2003-04-08 Iomed, Inc. High current density iontophoretic device and method of use thereof
CA2426600A1 (en) 2000-10-31 2002-05-23 Smith & Nephew, Inc. Packaging and delivery system for bone graft particles
US20030060447A1 (en) 2002-04-24 2003-03-27 Mutlu Karakelle Non-aspirating transitional viscoelastics for use in surgery
JP2002177392A (ja) 2000-11-08 2002-06-25 West Pharmaceutical Services Inc 注射器安全装置
US6915901B2 (en) 2000-12-11 2005-07-12 Marc Feinberg Packaging assembly for surgical use
EP1345646A2 (en) 2000-12-14 2003-09-24 Georgia Tech Research Corporation Microneedle devices and production thereof
US6387078B1 (en) 2000-12-21 2002-05-14 Gillespie, Iii Richard D. Automatic mixing and injecting apparatus
US20030171722A1 (en) 2001-01-04 2003-09-11 Michel Paques Microsurgical injection and/or distending instruments and surgical method and apparatus utilizing same
MXPA03006394A (es) 2001-01-18 2003-10-15 Univ California Instrumento quirurgico paraglaucoma minimamente invasivo y metodo.
JP4083425B2 (ja) 2001-01-25 2008-04-30 テルモ株式会社 液体注入針および液体注入装置
US6656433B2 (en) 2001-03-07 2003-12-02 Churchill Medical Systems, Inc. Vial access device for use with various size drug vials
US7052829B2 (en) 2001-03-30 2006-05-30 The Arizona Board Of Regents On Behalf Of The University Of Arizona Prevascularized constructs for implantation to provide blood perfusion
US20090088721A1 (en) 2001-04-17 2009-04-02 Eyegate Pharma S.A.S. Enhanced retinal delivery of a nucleic acid through iontophoresis
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US20030073609A1 (en) 2001-06-29 2003-04-17 Pinkerton Thomas C. Enhanced pharmacokinetic profile of intradermally delivered substances
US6749792B2 (en) 2001-07-09 2004-06-15 Lifescan, Inc. Micro-needles and methods of manufacture and use thereof
MXPA04001505A (es) 2001-07-24 2004-05-31 Artes Medical Usa Inc Jeringa alargada.
JP2003052819A (ja) 2001-08-10 2003-02-25 Seikagaku Kogyo Co Ltd 薬剤充填注射器包装物およびその滅菌または殺菌方法
WO2003022330A2 (en) 2001-09-12 2003-03-20 Becton, Dickinson And Company Microneedle-based pen device for drug delivery and method for using same
US8361037B2 (en) 2001-09-19 2013-01-29 Valeritas, Inc. Microneedles, microneedle arrays, and systems and methods relating to same
US8920375B2 (en) 2001-09-21 2014-12-30 Valeritas, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
CA2461370A1 (en) 2001-09-26 2003-05-15 F. Hoffmann-La Roche Ag Method and apparatus for sampling bodily fluid
US6715520B2 (en) 2001-10-11 2004-04-06 Carmel Pharma Ab Method and assembly for fluid transfer
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US7349733B2 (en) 2001-11-02 2008-03-25 Ceramatel, Inc. Iontophoretic drug delivery systems
US7569035B1 (en) 2001-11-02 2009-08-04 Meridian Medical Technologies, Inc. Automatic injector with anti-coring needle
DE60236949D1 (de) 2001-11-09 2010-08-19 Alza Corp Pneumatisch angetriebener autoinjektor
ATE367780T1 (de) 2001-11-22 2007-08-15 Eduard Anton Haefliger Vorrichtung zur durchführung ophtalmologischer eingriffe
GB0127983D0 (en) 2001-11-22 2002-01-16 Neutec Pharma Plc Treatment of micro-organism infection
US7204823B2 (en) 2001-12-19 2007-04-17 Medtronic Minimed, Inc. Medication delivery system and monitor
US6821286B1 (en) 2002-01-23 2004-11-23 Cardica, Inc. System for preparing a graft vessel for anastomosis
US6875205B2 (en) 2002-02-08 2005-04-05 Alaris Medical Systems, Inc. Vial adapter having a needle-free valve for use with vial closures of different sizes
US20050033230A1 (en) 2002-02-15 2005-02-10 Alchas Paul G. Prefillable intradermal delivery device with hidden needle and passive shielding
WO2003070296A2 (en) * 2002-02-15 2003-08-28 Antares Pharma, Inc. Injector with bypass channel
PT1484054E (pt) 2002-02-22 2012-11-28 Santen Pharmaceutical Co Ltd Sistema de administração de fármaco para administração subconjuntival de partículas finas
MXPA04008797A (es) 2002-03-13 2004-11-26 Janssen Pharmaceutica Nv Inhibidores de histona desacetilasa.
EP1496878A4 (en) 2002-04-12 2007-12-26 Celgene Corp TECHNIQUES FOR IDENTIFYING ANGIOGENESIS MODULATORS, COMPOUNDS DISCOVERED BY THESE TECHNIQUES AND TREATMENT TECHNIQUES USING THESE COMPOUNDS
GB0208627D0 (en) * 2002-04-16 2002-05-22 Imprint Pharm Ltd Needle
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
EP1511528A4 (en) 2002-05-16 2008-07-02 Scott Lab Inc MECHANISMS FOR PENETRATION IN A MEDICINAL CONTAINER, AND ASSOCIATED METHOD
US6979316B1 (en) 2002-05-23 2005-12-27 Seedlings Life Science Ventures Llc Apparatus and method for rapid auto-injection of medication
AU2003243750A1 (en) 2002-06-25 2004-01-06 Sung-Yun Kwon Rapidly dissolving micro-perforator for drug delivery and other applications
US6945952B2 (en) 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
ATE349235T1 (de) 2002-07-11 2007-01-15 Tecpharma Licensing Ag Vorrichtung für die intradermale und subkutane injektion
US7316676B2 (en) 2002-08-20 2008-01-08 Gholam A. Peyman Treatment of retinal detachment
DE10242984B4 (de) 2002-09-17 2010-09-23 Sanatis Gmbh Vorrichtung zum Herstellen von Gemischen aus zwei Komponenten
CN1301692C (zh) 2002-09-18 2007-02-28 阿勒根公司 眼植入物导入的器械
EP1590034B1 (en) 2002-10-07 2014-05-14 Biovalve Technologies, Inc. Microneedle array patch
IL152271A (en) 2002-10-13 2006-04-10 Meir Hefetz Structures of micro needles and manufacturing methods
US6883222B2 (en) 2002-10-16 2005-04-26 Bioject Inc. Drug cartridge assembly and method of manufacture
JP2004196787A (ja) 2002-12-04 2004-07-15 Santen Pharmaceut Co Ltd 結膜下デポによるドラッグデリバリーシステム
CN100453066C (zh) 2002-12-04 2009-01-21 参天制药株式会社 利用结膜下储存库的药物释放系统
CA2510196C (en) 2002-12-20 2014-04-01 Generipharm, Inc. Intracutaneous injection
KR100563330B1 (ko) 2003-01-16 2006-03-22 포스트마이크로 주식회사 Ｌｉｇａ공정을 이용한 폴리머 재질의 미세 바늘 어레이제조방법
EP1590024B1 (en) 2003-01-21 2016-04-27 Carmel Pharma AB A needle for penetrating a membrane
GB0301934D0 (en) 2003-01-28 2003-02-26 Sundar Satish Delivery apparatus and location method
US7578954B2 (en) 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
WO2004082745A1 (fr) 2003-02-24 2004-09-30 Becton Dickinson France Plateau pour le groupage d'objets de corps de seringue
DK1454609T3 (da) 2003-03-05 2013-02-11 Csl Behring Gmbh Overføringsindretning
US20040186084A1 (en) 2003-03-21 2004-09-23 Akorn, Inc. Triamcinolone formulations and methods for their preparation and use
US20050070819A1 (en) 2003-03-31 2005-03-31 Rosedale Medical, Inc. Body fluid sampling constructions and techniques
US20040199130A1 (en) 2003-04-03 2004-10-07 Chornenky Victor I. Apparatus and method for treatment of macular degeneration
US7533514B2 (en) 2003-04-25 2009-05-19 Boston Scientific Scimed, Inc. Method and apparatus for automated handling of medical devices during manufacture
US7824373B2 (en) * 2003-05-28 2010-11-02 Ducksoo Kim Self-contained power-assisted syringe
US8403941B2 (en) 2003-06-02 2013-03-26 Abbott Medical Optics Inc. Intraocular lens and cartridge packaging with lens-loading function
US7435237B2 (en) 2003-06-02 2008-10-14 Boston Scientific Scimed, Inc. Mixing syringes with breakable septums
FR2855761B1 (fr) 2003-06-03 2006-02-24 Optis France Sa Dispositif oculaire de delivrance variable de principes actifs par iontophorese
AU2004251699A1 (en) 2003-06-04 2005-01-06 Georgia Tech Research Corporation Drilling microneedle device
US7025389B2 (en) 2003-06-06 2006-04-11 Baxter International Inc. Method and device for transferring fluid
DE10327119A1 (de) 2003-06-13 2004-12-30 Aventis Pharma Deutschland Gmbh Kappe für Injektionsvorrichtungen
US7914803B2 (en) 2003-06-13 2011-03-29 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of three polymers
JP2007526013A (ja) 2003-06-16 2007-09-13 ソルクス インコーポレイテッド 緑内障を治療するためのシャント装置
PL1638468T3 (pl) 2003-06-30 2008-01-31 Alza Corp Sposób powlekania mikrowystępów do przekłuwania skóry
USD499153S1 (en) 2003-07-08 2004-11-30 Test Rite International Company, Ltd Handle for jump rope
US20050009910A1 (en) 2003-07-10 2005-01-13 Allergan, Inc. Delivery of an active drug to the posterior part of the eye via subconjunctival or periocular delivery of a prodrug
RU2006113593A (ru) 2003-09-23 2006-08-27 Алькон, Инк. (Ch) Препаративные формы триамцинолона ацетонида и анекортава ацетата для инъекций
US7481818B2 (en) 2003-10-20 2009-01-27 Lifescan Lancing device with a floating probe for control of penetration depth
WO2005044364A1 (en) 2003-11-10 2005-05-19 Agency For Science, Technology And Research Microneedles and microneedle fabrication
US20050101582A1 (en) 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
US20070224278A1 (en) 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
US20090148527A1 (en) 2007-12-07 2009-06-11 Robinson Michael R Intraocular formulation
US20060141049A1 (en) 2003-11-12 2006-06-29 Allergan, Inc. Triamcinolone compositions for intravitreal administration to treat ocular conditions
US20050101882A1 (en) 2003-11-12 2005-05-12 Leira Enrique C. Safety pressure device for body fluid extraction
CN1950124B (zh) 2004-01-12 2010-11-10 Ⅰ科学外科公司 一种输送粘性材料的注射器
DE602005011928D1 (de) 2004-01-20 2009-02-05 Allergan Inc Zusammensetzungen für die lokalisierte therapie des auges, vorzugsweise enthaltend triamcinolon-acetonid und hyaluronsäure
DE602005025599D1 (de) 2004-01-23 2011-02-10 Iscience Interventional Corp Zusammengesetzte ophthalmische mikrokanüle
EP1711186A4 (en) 2004-02-04 2009-03-18 Retmed Pty Ltd SLOWLY RELEASED STEROID COMPOSITION
US7678077B2 (en) 2004-02-20 2010-03-16 Boston Scientific Scimed, Inc. Variable depth injection device and method
WO2005091922A2 (en) 2004-03-03 2005-10-06 Becton, Dickinson And Company Methods and devices for improving delivery of a substance to skin
US7819822B2 (en) 2004-03-06 2010-10-26 Roche Diagnostics Operations, Inc. Body fluid sampling device
US7108679B2 (en) 2004-03-11 2006-09-19 Becton, Dickinson And Company Intradermal syringe and needle assembly
US20050203575A1 (en) 2004-03-15 2005-09-15 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Skin microactivation system and method
US7361168B2 (en) 2004-04-21 2008-04-22 Acclarent, Inc. Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders
EP2380622A1 (en) 2004-04-29 2011-10-26 iScience Interventional Corporation Method for ocular treatment
US20100173866A1 (en) 2004-04-29 2010-07-08 Iscience Interventional Corporation Apparatus and method for ocular treatment
US20080058704A1 (en) 2004-04-29 2008-03-06 Michael Hee Apparatus and Method for Ocular Treatment
US8685435B2 (en) 2004-04-30 2014-04-01 Allergan, Inc. Extended release biodegradable ocular implants
AU2005247122C1 (en) 2004-04-30 2012-02-02 Eyegate Pharma S.A. Irritation-reducing ocular iontophoretic device
US20050244462A1 (en) 2004-04-30 2005-11-03 Allergan, Inc. Devices and methods for treating a mammalian eye
US20050244469A1 (en) 2004-04-30 2005-11-03 Allergan, Inc. Extended therapeutic effect ocular implant treatments
US20050244463A1 (en) 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular vasculopathies
US8690865B2 (en) 2004-05-28 2014-04-08 Georgia Tech Research Corporation Methods and devices for thermal treatment
US8323227B2 (en) 2004-07-02 2012-12-04 C. R. Bard, Inc. Tip configurations for a multi-lumen catheter
WO2006017347A2 (en) 2004-07-12 2006-02-16 Allergan, Inc. Opthalmic compositions and methods for treating ophthalmic conditions
US7615041B2 (en) 2004-07-29 2009-11-10 Boston Scientific Scimed, Inc. Vial adaptor
US7503920B2 (en) 2004-08-11 2009-03-17 Tzony Siegal Spinal surgery system and method
US7722669B2 (en) 2004-08-13 2010-05-25 Richard Foulkes Method and insert for modifying eye color
JP4771043B2 (ja) 2004-09-06 2011-09-14 日本電気株式会社 薄膜半導体素子及びその駆動回路並びにそれらを用いた装置
US8114110B2 (en) 2004-09-22 2012-02-14 St. Jude Medical, Atrial Fibrillation Division, Inc. Transseptal puncture needle and needle assemblies
WO2006042252A2 (en) 2004-10-08 2006-04-20 Potentia Pharmeceuticals, Inc. Viral complement control proteins for eye disorders
US7627938B2 (en) 2004-10-15 2009-12-08 Board Of Regents, The Univeristy Of Texas System Tapered hollow metallic microneedle array assembly and method of making and using the same
US7097776B2 (en) 2004-10-22 2006-08-29 Hewlett-Packard Development Company, L.P. Method of fabricating microneedles
US7604647B2 (en) 2004-10-22 2009-10-20 Medical Instrument Development Laboratories, Inc. Ophthalmic cannula insertion tool and method
AU2005306309A1 (en) 2004-11-17 2006-05-26 Government Of The U.S.A., As Represented By The Secretary, Department Of Health & Human Services Steroid formulation and methods of treatment using same
US7648482B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems, and methods for medicament delivery
JP2008520397A (ja) 2004-11-23 2008-06-19 エドワード・ケイ・ジュニアー・ウォング 眼及び眼の周囲組織の温度制御及び治療のための医療装置
US8262715B2 (en) 2004-11-23 2012-09-11 Eye Delivery System, Llc Medical device and method for temperature control and treatment of the eye and surrounding tissues via magnetic drug therapy
US20060173418A1 (en) 2004-12-13 2006-08-03 Arrow International, Inc. Loss of resistance syringe
EP2505168A1 (en) 2004-12-16 2012-10-03 Iscience Interventional Corporation Ophthalmic Implant for Treatment of Glaucoma
US20060169664A1 (en) 2004-12-28 2006-08-03 Holopack International Corp. Vial for filling a syringe
US7803142B2 (en) 2005-02-02 2010-09-28 Summit Access Llc Microtaper needle and method of use
TW200640443A (en) 2005-02-23 2006-12-01 Alcon Inc Methods for treating ocular angiogenesis, retinal edema, retinal ischemia, and diabetic retinopathy using selective RTK inhibitors
US20060233858A1 (en) 2005-03-08 2006-10-19 Allergan, Inc. Systems and methods providing targeted intraocular drug delivery
WO2006099353A1 (en) 2005-03-11 2006-09-21 Alcon, Inc. Rnai-mediated inhibition of frizzled related protein-1 for treatment of glaucoma
US20070060904A1 (en) 2005-03-14 2007-03-15 Becton, Dickinson And Company Filling system and method for syringes with short needles
US8003124B2 (en) 2005-04-08 2011-08-23 Surmodics, Inc. Sustained release implants and methods for subretinal delivery of bioactive agents to treat or prevent retinal disease
US7722581B2 (en) 2005-04-11 2010-05-25 Gholam A. Peyman Crystalline lens drug delivery
US7645264B2 (en) * 2005-04-11 2010-01-12 Becton, Dickinson And Company Injection device with secondary reservoir
WO2006123248A2 (en) 2005-04-18 2006-11-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Improved methods and devices for delivering a therapeutic product to the ocular sphere of a subject
WO2006116621A2 (en) 2005-04-26 2006-11-02 Biolase Technology, Inc. Methods for treating eye conditions
US20060259008A1 (en) 2005-04-27 2006-11-16 Allergan, Inc. Apparatus and methods useful for intravitreal injection of drugs
CN100463668C (zh) 2005-05-09 2009-02-25 凌沛学 可逆性热凝胶化水性药物组合物
US7648491B2 (en) 2005-05-13 2010-01-19 Bob Rogers Medical substance transfer system
US20080269666A1 (en) 2005-05-25 2008-10-30 Georgia Tech Research Corporation Microneedles and Methods for Microinfusion
AU2006254825A1 (en) 2005-06-08 2006-12-14 Targegen, Inc. Methods and compositions for the treatment of ocular disorders
WO2006138719A2 (en) 2005-06-17 2006-12-28 Georgia Tech Research Corporation Coated microstructures and method of manufacture thereof
CN100430069C (zh) 2005-07-28 2008-11-05 凌沛学 一种中药及其复方的可逆性热凝胶化水性药物组合物
ES2371557T3 (es) 2005-08-11 2012-01-05 Medimop Medical Projects Ltd. Dispositivos de transferencia de fármacos líquidos para un correcto ajuste a presión a prueba de fallos en viales medicinales.
WO2007038687A2 (en) 2005-09-27 2007-04-05 Aciont, Inc. Ocular administration of immunosuppressive agents
US20090082321A1 (en) 2007-09-21 2009-03-26 Allergan, Inc. Steroid containing drug delivery systems
US8634907B2 (en) 2005-10-24 2014-01-21 Aciont, Inc. Intraocular iontophoretic device and associated methods
US20070093877A1 (en) 2005-10-26 2007-04-26 Beecham Michael C System for maintaining normal health of retinal cells and promoting regeneration of retinal cells
WO2007058966A1 (en) 2005-11-11 2007-05-24 Massachusetts Institute Of Technology Controlled needle-free eye injector
CA2627392A1 (en) 2005-11-14 2007-05-24 Pactiv Corporation Container having internal reservoir
FR2893852B1 (fr) 2005-11-29 2010-09-03 Eyegate Pharma Sa Dispositif d'iontophorese oculaire
US8099162B2 (en) 2005-11-29 2012-01-17 Eyegate Pharma, S.A.S. Ocular iontophoresis device
US20070123947A1 (en) 2005-11-30 2007-05-31 Wenger William K Medical device packaging system
JP2007159658A (ja) 2005-12-09 2007-06-28 Fujifilm Corp 採血針
JP4358821B2 (ja) 2005-12-15 2009-11-04 オリンパス株式会社 被検体内導入装置
US9107673B2 (en) 2005-12-23 2015-08-18 Cathrx Ltd. Irrigation catheter
US7981101B2 (en) 2005-12-30 2011-07-19 Carefusion 303, Inc. Medical vial adapter with reduced diameter cannula and enlarged vent lumen
EP1978892B1 (en) 2006-01-17 2017-11-15 Novartis Ag Drug delivery treatment device
EP1979023B1 (en) 2006-01-17 2015-07-22 Transcend Medical, Inc. Glaucoma treatment device
US20070185495A1 (en) 2006-01-30 2007-08-09 Howmedica International S. De R. L. Plug-in syringe stand
DE502006005333D1 (de) 2006-02-16 2009-12-24 Roche Diagnostics Gmbh System und Vorrichtung zum Entnehmen von Pharmazeutika
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US20080015539A1 (en) 2006-02-28 2008-01-17 Robert Pieroni Bottle with adapter for receiving needleless syringe
FR2898812B1 (fr) 2006-03-24 2008-06-13 Technoflex Sa Connecteur luer, connecteur medical et set de transfert comportant un tel connecteur
US7547300B2 (en) 2006-04-12 2009-06-16 Icu Medical, Inc. Vial adaptor for regulating pressure
DE602006016996D1 (de) 2006-04-27 2010-10-28 Ecolab Inc Produktgehäuse für einen Festproduktspender
US7918814B2 (en) 2006-05-02 2011-04-05 Georgia Tech Research Corporation Method for drug delivery to ocular tissue using microneedle
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US20210393436A1 (en) 2006-05-02 2021-12-23 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US20070270768A1 (en) 2006-05-17 2007-11-22 Bruno Dacquay Mechanical Linkage Mechanism For Ophthalmic Injection Device
US20070270745A1 (en) 2006-05-18 2007-11-22 Camran Nezhat Vacuum actuated tissue lifting device
USD598543S1 (en) 2006-06-13 2009-08-18 Angiomed Gmbh & Co. Medizintechnik Kg Handle for a medical delivery device
US8668676B2 (en) 2006-06-19 2014-03-11 Allergan, Inc. Apparatus and methods for implanting particulate ocular implants
US20070299386A1 (en) 2006-06-23 2007-12-27 Minu, L.L.C. Delivery of an ocular agent using iontophoresis
US8802128B2 (en) 2006-06-23 2014-08-12 Allergan, Inc. Steroid-containing sustained release intraocular implants and related methods
US8974511B2 (en) 2010-11-15 2015-03-10 Aquesys, Inc. Methods for treating closed angle glaucoma
US8852137B2 (en) 2010-11-15 2014-10-07 Aquesys, Inc. Methods for implanting a soft gel shunt in the suprachoroidal space
US8663303B2 (en) 2010-11-15 2014-03-04 Aquesys, Inc. Methods for deploying an intraocular shunt from a deployment device and into an eye
US9205075B2 (en) 2006-07-12 2015-12-08 Mobius Therapeutics, Llc Apparatus and method for reconstituting a pharmaceutical and preparing the reconstituted pharmaceutical for transient application
WO2008011125A2 (en) 2006-07-20 2008-01-24 Neurosystec Corporation Devices, systems and methods for ophthalmic drug delivery
WO2008013913A2 (en) 2006-07-26 2008-01-31 Aciont, Inc. Method and device for minimally invasive site specific ocular drug delivery
US9039761B2 (en) 2006-08-04 2015-05-26 Allergan, Inc. Ocular implant delivery assemblies with distal caps
WO2008020632A1 (en) 2006-08-18 2008-02-21 Toppan Printing Co., Ltd. Microneedle and microneedle patch
US20080058717A1 (en) 2006-09-04 2008-03-06 Spector David M Oral cavity liquid delivery system including pre-angled needle guidance assembly and method for using the same
US20080065002A1 (en) 2006-09-07 2008-03-13 Neurosystec Corporation Catheter for Localized Drug Delivery and/or Electrical Stimulation
WO2008033426A1 (en) 2006-09-12 2008-03-20 Psivida Inc. Injector apparatus and method of use
US8944069B2 (en) 2006-09-12 2015-02-03 Vidacare Corporation Assemblies for coupling intraosseous (IO) devices to powered drivers
US20080097346A1 (en) 2006-09-19 2008-04-24 Alcon, Inc. Trocar cannula
US20080097379A1 (en) * 2006-09-26 2008-04-24 Alcon Manufacturing, Ltd. Ophthalmic injection method
US20080097390A1 (en) 2006-09-27 2008-04-24 Alcon Manufacturing, Ltd. Spring actuated delivery system
US7849334B2 (en) 2006-09-29 2010-12-07 Intel Coporation Transitioning a computing platform to a low power system state
US8167863B2 (en) 2006-10-16 2012-05-01 Carefusion 303, Inc. Vented vial adapter with filter for aerosol retention
US20080234625A1 (en) 2006-10-16 2008-09-25 Bruno Dacquay Fuse Assembly For Single Use Medical Device
WO2008061043A2 (en) 2006-11-10 2008-05-22 Glaukos Corporation Uveoscleral shunt and methods for implanting same
EP2091482A2 (en) 2006-12-01 2009-08-26 Allergan, Inc. Method for determining optimum intraocular locations for drug delivery systems
US8969415B2 (en) 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems
RU2344767C2 (ru) 2006-12-18 2009-01-27 Наталья Александровна Уракова Способ внутриартериальной инъекции по а.л. уракову
DK2124856T3 (en) 2007-01-09 2019-02-11 Fovea Pharmaceuticals DEVICE FOR INTRAOCULAR INJECTION
US20080177239A1 (en) 2007-01-18 2008-07-24 Yong Li Trocar cannula system
ES2438041T3 (es) 2007-02-08 2014-01-15 Arnaldo Goncalves Dispositivo para administración intraocular de una substancia, por ejemplo un medicamento, en un ojo humano o animal mediante una aguja hipodérmica
US7883499B2 (en) 2007-03-09 2011-02-08 Icu Medical, Inc. Vial adaptors and vials for regulating pressure
GB0705782D0 (en) 2007-03-26 2007-05-02 Novartis Ag Vial assemblies
DE102007018696A1 (de) 2007-04-18 2008-10-23 Sanofi-Aventis Deutschland Gmbh Injektionsvorrichtung zur Abgabe eines Medikaments
US7975733B2 (en) 2007-05-08 2011-07-12 Carmel Pharma Ab Fluid transfer device
USD590690S1 (en) 2007-05-24 2009-04-21 Domino S.P.A. Handlebar hand grip
US8216312B2 (en) 2007-05-31 2012-07-10 Zimmer Spine, Inc. Spinal interbody system and method
WO2009012406A1 (en) 2007-07-17 2009-01-22 Transcend Medical, Inc. Ocular implant with hydrogel expansion capabilities reference to priority document
US20090030381A1 (en) 2007-07-23 2009-01-29 Lind Casey J Arced Hypodermic Needle
WO2009023247A1 (en) 2007-08-16 2009-02-19 East Carolina University Smart injection syringe systems providing real-time user feedback of correct needle position
CA2704933A1 (en) 2007-08-21 2009-02-26 Yukon Medical, Llc Vial access and injection system
CA2639322C (en) 2007-09-07 2016-11-08 Becton, Dickinson And Company Pen needle hub having increased contact area
RU2482822C2 (ru) 2007-09-07 2013-05-27 Клт Инк. Инструменты для вставления и извлечения лакримальных имплантатов
US20090076463A1 (en) 2007-09-17 2009-03-19 Jurg Attinger Trocar Cannula
US20090082713A1 (en) 2007-09-20 2009-03-26 Friden Phillip M Method of enhancing iontophoretic delivery of a peptide
US20090081277A1 (en) 2007-09-21 2009-03-26 Allergan, Inc. Pharmaceutical formulations and methods for treating ocular conditions
IL186290A0 (en) 2007-09-25 2008-01-20 Medimop Medical Projects Ltd Liquid drug delivery devices for use with syringe having widened distal tip
US8083759B2 (en) 2007-11-02 2011-12-27 Refocus Ocular, Inc. Apparatuses and methods for forming incisions in ocular tissue
CA2708445C (en) 2007-12-17 2016-11-01 New World Pharmaceuticals, Llc Integrated intra-dermal delivery, diagnostic and communication system
US8631935B2 (en) 2009-06-03 2014-01-21 Medline Industries, Inc. Catheter tray, packaging system, and associated methods
US8448786B2 (en) 2009-06-30 2013-05-28 Medline Industries, Inc. Catheter tray, packaging system, instruction insert, and associated methods
US8602959B1 (en) 2010-05-21 2013-12-10 Robert Park Methods and devices for delivery of radiation to the posterior portion of the eye
CA2711588C (en) 2008-01-09 2017-03-14 Novartis Ag Unitary withdrawal spike unit suitable for factory fitting
JP2009183441A (ja) 2008-02-06 2009-08-20 Ken Kondo 静脈留置針組立体
US8469939B2 (en) 2008-02-18 2013-06-25 Icu Medical, Inc. Vial adaptor
US20100081707A1 (en) 2008-02-21 2010-04-01 Ali Robin R Devices and methods for delivering polynucleotides into retinal cells of the macula and fovea
US20100152646A1 (en) 2008-02-29 2010-06-17 Reshma Girijavallabhan Intravitreal injection device and method
JP5581227B2 (ja) 2008-03-11 2014-08-27 アルコン リサーチ， リミテッド 硝子体内注射のための低粘度、高凝集トリアムシノロンアセトニド懸濁剤
FR2928536B1 (fr) 2008-03-14 2012-04-27 Inst Nat Sante Rech Med Dispositif d'injection dans l'oeil
US20090259180A1 (en) 2008-04-11 2009-10-15 Jong Soo Choi Injection method using injector with length-adjustable needle and injection apparatus using the same
CN201192452Y (zh) 2008-04-15 2009-02-11 黄蛟龙 一种气动式按摩装置
CN101559249A (zh) 2008-04-18 2009-10-21 崔钟洙 使用具有长度可调针头的注射器的注射方法及注射装置
US20090287161A1 (en) 2008-05-15 2009-11-19 Allergan, Inc Metered, multiple dose/aliquot syringe
US20090312782A1 (en) 2008-06-13 2009-12-17 Maxwell Choongwon Park Method and apparatus for repairing tendons
US9022940B2 (en) 2008-07-18 2015-05-05 Joseph H. Meier Handheld imaging devices and related methods
US8821870B2 (en) 2008-07-18 2014-09-02 Allergan, Inc. Method for treating atrophic age related macular degeneration
WO2010011270A2 (en) 2008-07-21 2010-01-28 Smiths Medical Asd, Inc. Tray assembly
JP5476062B2 (ja) 2008-07-25 2014-04-23 南部化成株式会社 経皮投薬デバイス
CA2735289A1 (en) 2008-08-30 2010-03-04 Sanofi-Aventis Deutschland Gmbh Cartridge and needle system therefor
TWI580441B (zh) 2008-09-19 2017-05-01 愛爾康研究有限公司 穩定的藥學次微米懸浮液及其形成方法
US7678078B1 (en) 2008-10-21 2010-03-16 KMG Pharma LLC Intravitreal injection device, system and method
US20100098772A1 (en) 2008-10-21 2010-04-22 Allergan, Inc. Drug delivery systems and methods for treating neovascularization
US8221353B2 (en) * 2008-10-21 2012-07-17 KMG Pharma, Inc Intravitreal injection device and system
WO2010054660A1 (en) 2008-11-11 2010-05-20 Herlev Hospital Double cannula system for anaesthetic needle
US20120059346A1 (en) 2008-11-12 2012-03-08 British Columbia Cancer Agency Branch Vial handling and injection safety systems and connectors
WO2010065970A1 (en) 2008-12-05 2010-06-10 Ivantis, Inc. Methods and apparatus for delivering ocular implants into the eye
US20110282298A1 (en) 2008-12-09 2011-11-17 Nadav Agian Device for injecting fluid isolated from microneedle hub with dead-space-reducing insert
WO2010066590A1 (en) 2008-12-12 2010-06-17 Shl Group Ab Medicament delivery device
US20100152676A1 (en) * 2008-12-16 2010-06-17 Alcon Research, Ltd. Drug Loading Through Plunger
US20100160889A1 (en) 2008-12-22 2010-06-24 Baxter International Inc. Vial access spike assembly
US8512309B2 (en) 2009-01-15 2013-08-20 Teva Medical Ltd. Vial adapter element
US8545554B2 (en) 2009-01-16 2013-10-01 Allergan, Inc. Intraocular injector
US8425473B2 (en) 2009-01-23 2013-04-23 Iscience Interventional Corporation Subretinal access device
US20100191177A1 (en) 2009-01-23 2010-07-29 Iscience Interventional Corporation Device for aspirating fluids
ES2378012B1 (es) 2009-01-29 2013-02-12 Innova Salud Desarrollos Sanitarios S.L. Dispositivo para la administración de productos inyectables con caudal controlado.
US8162914B2 (en) 2009-02-10 2012-04-24 Kraushaar Timothy Y Cap adapters for medicament vial and associated methods
WO2010093662A2 (en) 2009-02-10 2010-08-19 Psivida Us, Inc. Ocular trocar assembly
US8123736B2 (en) 2009-02-10 2012-02-28 Kraushaar Timothy Y Cap adapters for medicament vial and associated methods
US8057483B2 (en) 2009-02-14 2011-11-15 Ocular Transplantation Llc Subretinal implantation instrument
CN201356711Y (zh) 2009-02-23 2009-12-09 徐学农 玻璃体腔冲洗针头
US20120095438A1 (en) 2009-03-02 2012-04-19 Sanofi-Aventis Deutschland Gmbh Medication delivery device with foldable finger pad
CA2753919A1 (en) 2009-03-05 2010-09-10 Sanofi-Aventis Deutschland Gmbh Drug delivery device
JP5570533B2 (ja) 2009-03-05 2014-08-13 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ニードルユニット
CA2763555A1 (en) 2009-03-05 2010-09-10 Sanofi-Aventis Deutschland Gmbh Needle assembly
JP5608686B2 (ja) 2009-03-05 2014-10-15 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 後退可能な針を備えた薬物送達デバイス
WO2010100245A1 (en) 2009-03-06 2010-09-10 Sanofi-Aventis Deutschland Gmbh Drug delivery device with retractable needle
US8287494B2 (en) * 2009-03-23 2012-10-16 Colin Ma Intravitreal injection devices and methods of injecting a substance into the vitreous chamber of the eye
SE0900371A1 (sv) 2009-03-24 2010-09-25 Istvan Bartha Anordning för distribution av flytande läkemedel
JP4505561B1 (ja) 2009-03-30 2010-07-21 篤志 今津 圧力式穿刺注射器
WO2010119392A1 (en) 2009-04-15 2010-10-21 Koninklijke Philips Electronics N.V. Needle with integrated fibers in the cutting facets of the bevel
US20120130207A1 (en) 2009-04-29 2012-05-24 Janisys Limited micro-needle device and apparatus and a method for applying a micro-needle element to a site on the skin of a subject
JP2012526637A (ja) 2009-05-15 2012-11-01 アイサイエンス・インターベンショナル・コーポレーション 網膜下カテーテル挿入のための方法及び装置
US8795226B2 (en) 2009-06-25 2014-08-05 Sanofi-Aventis Deutschland Gmbh Cannula assembly for co-delivery of medicaments
RU2428956C2 (ru) 2009-07-13 2011-09-20 Александр Дмитриевич Ромащенко Способ лечения атрофии зрительного нерва посредством трансплантации аутологичных стволовых клеток
US9089655B2 (en) * 2009-07-23 2015-07-28 Sid Technologies, Llc Intradermal injection adapter
US8535333B2 (en) 2009-07-29 2013-09-17 Transcend Medical, Inc. Ocular implant applier and methods of use
IN2012DN02101A (https=) * 2009-08-10 2015-08-21 Evonik Corp
EP2464400B1 (en) 2009-08-12 2015-01-28 Sanofi-Aventis Deutschland GmbH Cap for a portable medical delivery device and such a medical delivery device
JP5762413B2 (ja) 2009-08-28 2015-08-12 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 事前に充填されたシリンジを製造するための組立体キット
EP2480270A4 (en) 2009-09-21 2015-07-08 Harvard Apparatus Regenerative Technology Inc METHOD AND DEVICE FOR INTRODUCING CELLS TO A TISSUE POSITION
WO2011050333A1 (en) 2009-10-23 2011-04-28 Amgen Inc. Vial adapter and system
WO2011057065A1 (en) 2009-11-06 2011-05-12 The Uab Research Foundation Apparatuses and methods for delivering substances to the inner eye
AU2010317659B2 (en) 2009-11-11 2014-01-23 Unitract Syringe Pty Ltd Clinical syringe
IL202069A0 (en) 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Fluid transfer device with sealing arrangement
US8480646B2 (en) 2009-11-20 2013-07-09 Carmel Pharma Ab Medical device connector
KR101875172B1 (ko) 2009-12-22 2018-07-06 유니트랙트 시린지 피티와이 엘티디 향상된 전달 효율 및 잠금 시스템을 갖는 퇴각 가능한 주사기
US8529492B2 (en) 2009-12-23 2013-09-10 Trascend Medical, Inc. Drug delivery devices and methods
US8343106B2 (en) 2009-12-23 2013-01-01 Alcon Research, Ltd. Ophthalmic valved trocar vent
US8961474B2 (en) 2010-01-05 2015-02-24 Allergan, Inc. Syringe
CN201591741U (zh) 2010-01-22 2010-09-29 苏开志 一种套管式针灸针
WO2011109388A2 (en) 2010-03-01 2011-09-09 Medical Instrument Development Laboratories, Inc. Cannula for intraocular surgery
EP2364740A1 (en) 2010-03-09 2011-09-14 Sanofi-Aventis Deutschland GmbH Arrangement for transferring a translation of a drive means to a plunger
GB201004102D0 (en) 2010-03-12 2010-04-28 Liversidge Barry P Syringe barrels and handling systems
US9327105B2 (en) 2010-03-26 2016-05-03 Itrace Biomedical Inc. Active transdermal drug delivery system and the method thereof
CN106137528B (zh) * 2010-03-31 2020-12-01 奥库杰克特有限责任公司 用于眼内药物递送的设备和方法
WO2011123722A1 (en) 2010-03-31 2011-10-06 Ocuject, Llc Device and method for intraocular drug delivery
US9320647B2 (en) 2010-03-31 2016-04-26 Ocuject, Llc Device and method for intraocular drug delivery
US9408746B2 (en) * 2010-03-31 2016-08-09 Ocuject, Llc Device and method for intraocular drug delivery
US8652118B2 (en) 2010-04-08 2014-02-18 Kmg Pharma, Llc Sub-mucosal agent delivery, apparatus, system and method
US8574217B2 (en) 2010-04-08 2013-11-05 Kmg Pharma, Llc Sub-mucosal agent delivery method for the eye
US8430862B2 (en) 2010-04-08 2013-04-30 KMG Pharma LLC Subconjunctival agent delivery apparatus, system and method
CN102869398B (zh) 2010-05-04 2015-08-26 尤尼特拉克特注射器公司 注射器筒适配器和针组件
US8632589B2 (en) 2010-05-04 2014-01-21 Abbott Medical Optics Inc. IOL insertion system with semi-automatic trailing haptic configuration management
US8932258B2 (en) 2010-05-14 2015-01-13 C. R. Bard, Inc. Catheter placement device and method
US8758306B2 (en) 2010-05-17 2014-06-24 Icu Medical, Inc. Medical connectors and methods of use
US20110295152A1 (en) 2010-05-25 2011-12-01 Nextier Corporation Puncture method, incision needle, puncture needle, needle cap and instrument for blood purification treatment
US8545430B2 (en) 2010-06-09 2013-10-01 Transcend Medical, Inc. Expandable ocular devices
EP2600923B1 (en) 2010-06-10 2018-08-08 Anthony J. Colantonio Apparatus and method for safely inserting an introducer needle into epidural space
EP2588098A1 (en) 2010-07-02 2013-05-08 Alcon Research, Ltd. Compounds for the treatment of posterior segment disorders and diseases
US8475009B2 (en) 2010-07-08 2013-07-02 Excelitas Technologies Corp. Tailored side-emitter perimeter beacon
KR101180032B1 (ko) 2010-07-12 2012-09-05 인싸이토(주) 외형 조절이 가능한 중공형 마이크로니들의 제조방법
TW201216948A (en) 2010-07-19 2012-05-01 Sanofi Aventis Deutschland Medicament cartridges with non-standard dimensions
EP3861969A1 (en) 2010-08-05 2021-08-11 ForSight Vision4, Inc. Injector apparatus for drug delivery
EP2621581A4 (en) 2010-09-30 2014-03-12 Evonik Corp BLADE FOR DRUG DELIVERY, AND METHODS OF DELIVERY OF A MEDICINE DEPOSIT TO A TARGET SITE
JP5843870B2 (ja) 2010-10-01 2016-01-13 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 解除機構を備えたニードルアセンブリ
EP2438939A1 (en) 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Arrangement for coupling a plunger to either a syringe or a stopper
JP5996544B2 (ja) 2010-10-15 2016-09-21 クリアサイド・バイオメディカル・インコーポレーテッドＣｌｅａｒｓｉｄｅ Ｂｉｏｍｅｄｉｃａｌ Ｉｎｃｏｒｐｏｒａｔｅｄ 眼球アクセス用装置
US20120101475A1 (en) 2010-10-21 2012-04-26 Meridian Medical Technologies, Inc. High Efficiency Auto-Injector
JP2013540028A (ja) 2010-10-25 2013-10-31 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 注射針の刺入深さを制御するためのデバイス
EP2446866A1 (en) 2010-11-02 2012-05-02 Fovea Pharmaceuticals Apparatus for injection into an eye
WO2012059456A1 (en) 2010-11-03 2012-05-10 Sanofi-Aventis Deutschland Gmbh Needle cannula containing medicament
US9241701B2 (en) 2010-11-11 2016-01-26 Depuy Mitek, Inc. Cannula system and method for partial thickness rotator cuff repair
JP5704389B2 (ja) 2010-11-29 2015-04-22 ニプロ株式会社 医療用中空針および医療用中空針の製造方法
US10285852B2 (en) 2010-12-02 2019-05-14 Tel Hashomer Medical Research Infrastructure And Services Ltd., The Chaim Sheba Medical Center Subretinal delivery of therapeutic compositions
US8608710B2 (en) 2010-12-09 2013-12-17 Becton Dickinson & Company Pen needle assembly with different gauge needle cannulas
US9968337B2 (en) 2010-12-20 2018-05-15 Cook Medical Technologies Llc Coring tissue biopsy needle and method of use
BR112013023724A2 (pt) 2011-03-15 2019-09-24 Univ Utah Res Found métodos para tratar doença ou sintoma, detriagem para um agente ou uma combinação de agentes, e para determinar a eficácia de um agente e de um tratamento
USD667111S1 (en) 2011-03-17 2012-09-11 Surgical Innovations Limited Handle for surgical instrument
EP2500002A1 (en) 2011-03-17 2012-09-19 Sanofi-Aventis Deutschland GmbH Apparatus for intraocular injection
US20140088552A1 (en) 2011-03-25 2014-03-27 The Curators Of The University Of Missouri Intravitreal Injection Device
WO2012131583A2 (en) 2011-03-27 2012-10-04 Microsert Ltd. Miniature implanted drug delivery devices and inserter systems for introducing such devices
EP2510911A1 (en) 2011-04-13 2012-10-17 Sanofi-Aventis Deutschland GmbH Apparatus for intraocular injection
EP2510902A1 (en) 2011-04-15 2012-10-17 Sanofi-Aventis Deutschland GmbH Intraocular injection device
IL212420A0 (en) 2011-04-17 2011-06-30 Medimop Medical Projects Ltd Liquid drug transfer assembly
EP2514684A1 (en) 2011-04-20 2012-10-24 Becton Dickinson France Packaging for medical containers
EP2514461A1 (en) 2011-04-20 2012-10-24 Sanofi-Aventis Deutschland GmbH Needle assembly for a medical device
EP2522318A1 (en) 2011-05-12 2012-11-14 Sanofi-Aventis Deutschland GmbH Guide device for intraocular injection
WO2012162459A1 (en) 2011-05-26 2012-11-29 Pepose Jay Device and method for administering eye medications
EP2540261A1 (en) 2011-06-30 2013-01-02 Sanofi-Aventis Deutschland GmbH Intraocular medicament delivery device
JP2014521460A (ja) 2011-08-05 2014-08-28 ユニトラクト シリンジ プロプライエタリイ リミテッド 挿入深さを制限したカニューレ
WO2013025696A1 (en) 2011-08-15 2013-02-21 Teva Pharmaceutical Industries Ltd. Ophthalmic formulations and processes for their preparation
US20150110717A1 (en) 2011-09-07 2015-04-23 Screencell Methods of increasing the number of target cells recovered from a fluid sample
EP2755705B1 (en) 2011-09-13 2015-11-25 Sanofi-Aventis Deutschland GmbH Injection device
EP2574355A1 (en) 2011-09-27 2013-04-03 Sanofi-Aventis Deutschland GmbH Package for a medicament delivery device
EP2578190A1 (en) 2011-10-07 2013-04-10 Sanofi-Aventis Deutschland GmbH Intraocular injection device
EP2578189A1 (en) 2011-10-07 2013-04-10 Sanofi-Aventis Deutschland GmbH Apparatus for intraocular injection
EP2578260A1 (en) 2011-10-07 2013-04-10 Sanofi-Aventis Deutschland GmbH Apparatus for intraocular injection
EP2578191A1 (en) 2011-10-07 2013-04-10 Sanofi-Aventis Deutschland GmbH Apparatus for intraocular injection
EP2586407A1 (en) 2011-10-31 2013-05-01 Sanofi-Aventis Deutschland GmbH Aid device for intraocular injection
EP2596826A1 (en) 2011-11-24 2013-05-29 Sanofi-Aventis Deutschland GmbH Safety syringe
EP2601988A1 (en) 2011-12-08 2013-06-12 Sanofi-Aventis Deutschland GmbH Syringe carrier
JP6298946B2 (ja) 2011-12-08 2018-03-28 ユーエヌエル ホールディングス エルエルシーＵＮＬ Ｈｏｌｄｉｎｇｓ ＬＬＣ 正確な投与制御機構及び薬物送達用注射器
EP2601990A1 (en) 2011-12-08 2013-06-12 Sanofi-Aventis Deutschland GmbH Syringe carrier
EP2601992A1 (en) 2011-12-08 2013-06-12 Sanofi-Aventis Deutschland GmbH Syringe carrier
EP2790754A1 (en) 2011-12-15 2014-10-22 Sanofi-Aventis Deutschland GmbH Reservoir or medicated module for a drug delivery system and method of and assembly for filling the same
ES2533576T3 (es) 2011-12-30 2015-04-13 Q-Med Ab Cánula sin hematomas
AU2013208998B2 (en) 2012-01-09 2016-10-06 Fresenius Kabi Deutschland Gmbh Port cannula for puncturing port catheters
CN102688542B (zh) * 2012-01-09 2013-09-25 吴晓楠 一种配合医用注射针筒使用的集成注射针头的装置
AU344164S (en) 2012-02-02 2012-09-04 Terumo Corp Safety device for indwelling needle
EP2626096A1 (en) 2012-02-10 2013-08-14 Sanofi-Aventis Deutschland GmbH Medicament delivery device with needle assembly removal mechanism
WO2013125443A1 (ja) 2012-02-20 2013-08-29 テルモ株式会社 医療用具梱包体
US9474594B2 (en) 2012-02-22 2016-10-25 Ira H. Schachar Device and method for treatment of retinal detachment and other maladies of the eye
MX364009B (es) 2012-02-23 2019-04-10 Unitract Syringe Pty Ltd Dispositivos para el suministro dirigido de implantes terapeuticos.
IN2014DN07707A (https=) 2012-02-23 2015-05-15 Shinmaywa Ind Ltd
USD672506S1 (en) 2012-02-28 2012-12-11 Idea Village Products, Inc. Exfoliating device
CN104135986A (zh) 2012-02-29 2014-11-05 赛诺菲-安万特德国有限公司 用于从容器单次提取药物的提取装置
AU2013232259B2 (en) 2012-03-12 2017-10-19 Unitract Syringe Pty Ltd Fill-finish cartridges for sterile fluid pathway assemblies and drug delivery devices incorporating fill-finish cartridges
EP2641629A1 (en) 2012-03-22 2013-09-25 Sanofi-Aventis Deutschland GmbH Medical injection device with injection site pain reduction device
US9421129B2 (en) 2012-04-02 2016-08-23 Ocuject, Llc Intraocular delivery devices and methods therefor
CN202554227U (zh) * 2012-04-23 2012-11-28 郭涛 眼内冲洗器
US9833523B2 (en) 2012-04-24 2017-12-05 The Ohio State University Pharmacokinetic determination of intravitreal agents
US9889248B2 (en) 2012-05-21 2018-02-13 Baxalta GmbH Syringe storage tray
ES2664719T3 (es) 2012-06-14 2018-04-23 Asahi Kasei Medical Co., Ltd. Aguja de punción
US9956341B2 (en) 2012-07-03 2018-05-01 Milestone Scientific, Inc. Drug infusion with pressure sensing and non-continuous flow for identification of and injection into fluid-filled anatomic spaces
US8727117B2 (en) 2012-07-16 2014-05-20 Becton, Dickinson And Company Package for syringe
US10201655B2 (en) 2012-08-13 2019-02-12 The Brigham And Women's Hospital, Inc. Methods and devices for inserting a needle
EP2887982B1 (en) 2012-08-27 2022-11-23 Clearside Biomedical, Inc. Apparatus for drug delivery using microneedles
USD715125S1 (en) 2012-10-08 2014-10-14 The Ames Companies, Inc. Grip
MX373894B (es) 2012-11-08 2020-07-09 Clearside Biomedical Inc Métodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos.
WO2014105635A1 (en) 2012-12-27 2014-07-03 Sentiss Pharma Pvt.Ltd. Sterile ophthalmic pharmaceutical suspensions
US9022968B2 (en) 2013-01-08 2015-05-05 University Of South Florida Auto-regulation system for intraocular pressure
WO2014152959A1 (en) 2013-03-14 2014-09-25 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
US9211231B2 (en) 2013-03-14 2015-12-15 Carefusion 303, Inc. Vial adapter for side engagement of vial cap
US9597260B2 (en) 2013-03-15 2017-03-21 Becton Dickinson and Company Ltd. System for closed transfer of fluids
USD740098S1 (en) 2013-03-19 2015-10-06 Tong Yah Electronic Technology Co., Ltd. Vehicular handle
US9987163B2 (en) 2013-04-16 2018-06-05 Novartis Ag Device for dispensing intraocular substances
BR112015027762A2 (pt) 2013-05-03 2017-08-29 Clearside Biomedical Inc Aparelho e métodos para injeção ocular
WO2014197317A1 (en) 2013-06-03 2014-12-11 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using multiple reservoirs
SG11201600331YA (en) 2013-07-16 2016-02-26 3M Innovative Properties Co Hollow microneedle with bevel opening
JP6594869B2 (ja) 2013-08-02 2019-10-23 テル ハショメール メディカル リサーチ インフラストラクチュアー アンド サービス エルティーディー． 目に組成物を輸送するためのデバイス
CA2920632A1 (en) 2013-08-07 2015-02-12 Unitract Syringe Pty Ltd Luer connection adapters for syringes
EP3030292A4 (en) 2013-08-07 2017-03-15 Unitract Syringe Pty Ltd Luer connection adapters for retractable needle syringes
USD718602S1 (en) 2013-09-09 2014-12-02 Midwest Tool And Cutlery Company Hand grip for hand tools
WO2015036947A1 (fr) 2013-09-11 2015-03-19 Debiotech S.A. Dispositif d'insertion d'aiguille
TWI569841B (zh) 2013-10-10 2017-02-11 卡貝歐洲有限公司 藥物輸送裝置
USD713958S1 (en) 2013-12-05 2014-09-23 Becton, Dickinson And Company Pen needle outer cover
CA2933900A1 (en) 2013-12-20 2015-06-25 Georgia Tech Research Corporation Formulations and methods for targeted ocular delivery of therapeutic agents
ES2672327T3 (es) 2014-01-27 2018-06-13 Opia Technologies Dispositivo de iontoforesis ocular
USD726908S1 (en) 2014-02-06 2015-04-14 St. Jude Medical, Cardiology Division, Inc. Catheter handle
BR112016018570B1 (pt) 2014-02-12 2022-08-30 Gyroscope Therapeutics Limited Aparelho para a liberação de agente terapêutico em um olho
WO2015175954A1 (en) 2014-05-16 2015-11-19 Scifluor Life Sciences, Inc. Alpha v integrin antagonist compositions
BR112016029864A2 (pt) 2014-06-17 2017-08-22 Clearside Biomedical Inc métodos e dispositivos para tratamento de desordens oculares posteriores.
EP3157598A4 (en) 2014-06-20 2018-05-16 Clearside Biomedical, Inc. Variable diameter cannula and methods for controlling insertion depth for medicament delivery
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
CN107249522B (zh) 2014-09-19 2021-04-20 奥叙拉尔有限公司 眼科递送装置
WO2016042163A2 (en) 2014-09-19 2016-03-24 Medterials, Inc. Ophthalmic drug compositions
JP5828535B1 (ja) 2014-10-10 2015-12-09 石根 三井 矯正角膜クロスリンキング用コンタクトレンズ
USD750223S1 (en) 2014-10-14 2016-02-23 Clearside Biomedical, Inc. Medical injector for ocular injection
US20160106587A1 (en) 2014-10-16 2016-04-21 Incept, Llc Ocular gels or hydrogels and microinjectors
CN204364577U (zh) 2014-12-26 2015-06-03 林才桥 肌肉注射装置
EP4279064A3 (en) 2015-05-12 2024-02-28 Incept, LLC Drug delivery from hydrogels
CA3193470A1 (en) 2015-06-03 2016-12-08 Aquesys, Inc. Ab externo intraocular shunt placement
KR102398204B1 (ko) 2015-09-24 2022-05-16 벡톤 디킨슨 앤드 컴퍼니 바늘, 바늘을 구비한 주사기 조립체, 및 바늘을 구비한 채혈 장치
WO2017120600A1 (en) 2016-01-08 2017-07-13 Clearside Biomedical, Inc. Compositions and methods of treating wet age-related macular degeneration
CA3010862A1 (en) 2016-01-08 2017-07-13 Clearside Biomedical, Inc. Methods and devices for treating posterior ocular disorderswith aflibercept and other biologics
US10390901B2 (en) 2016-02-10 2019-08-27 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
WO2017158365A2 (en) 2016-03-16 2017-09-21 Oxular Limited Ophthalmic delivery device and ophthalmic active agent containing compositions
WO2017190142A1 (en) 2016-04-29 2017-11-02 Clearside Biomedical, Inc. Formulations and methods for reduction of intraocular pressure
EP3452165A1 (en) 2016-05-02 2019-03-13 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
IL305537B2 (en) 2016-08-12 2025-02-01 Clearside Biomedical Inc Devices and methods for adjusting the insertion depth of a needle for administering a drug
EP3554435B1 (en) 2016-12-15 2025-06-04 Clearside Biomedical, Inc. Systems for delivering drugs to retinal tissue
US12090294B2 (en) 2017-05-02 2024-09-17 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
US20190269702A1 (en) 2018-03-05 2019-09-05 Clearside Biomedical, Inc. Compositions and methods for treating noninfectious uveitis
US12142157B2 (en) 2020-05-22 2024-11-12 Clearside Biomedical, Inc. Apparatus and methods for fabricating and using a simulated anatomical tissue structure
EP4225235A4 (en) 2020-10-09 2024-08-14 Clearside Biomedical, Inc. DEVICE AND METHOD FOR RETINAL INJECTION
US20230363941A1 (en) 2020-10-09 2023-11-16 Clearside Biomedical, Inc. Apparatus and methods of retinal injection
WO2024015652A1 (en) 2022-07-15 2024-01-18 Clearside Biomedical, Inc. Systems, devices, and methods for needle-less ocular injections

Also Published As

Publication number Publication date
CA2911290C (en) 2021-07-27
US12201558B2 (en) 2025-01-21
BR112015027762A2 (pt) 2017-08-29
KR102282973B1 (ko) 2021-07-27
US20230157869A1 (en) 2023-05-25
EP4378444A3 (en) 2024-07-03
US20190231592A1 (en) 2019-08-01
IL286808A (en) 2021-10-31
US9180047B2 (en) 2015-11-10
JP6613342B2 (ja) 2019-11-27
US9636253B1 (en) 2017-05-02
EA032039B1 (ru) 2019-03-29
US20180333297A1 (en) 2018-11-22
EP2991706A2 (en) 2016-03-09
WO2014179698A4 (en) 2015-04-16
AU2014259694A1 (en) 2015-12-03
KR102406619B1 (ko) 2022-06-07
CN105246529A (zh) 2016-01-13
US20170112665A1 (en) 2017-04-27
IL242395B (en) 2021-10-31
EP2991706B1 (en) 2021-06-23
US20200030143A1 (en) 2020-01-30
CA3121759A1 (en) 2014-11-06
KR20160005735A (ko) 2016-01-15
CA2911290A1 (en) 2014-11-06
EP3417896A2 (en) 2018-12-26
EP4378444A2 (en) 2024-06-05
US20190350755A1 (en) 2019-11-21
CN116327482A (zh) 2023-06-27
EP3417896A3 (en) 2019-03-06
KR20210093394A (ko) 2021-07-27
US20150051581A1 (en) 2015-02-19
US20180028358A1 (en) 2018-02-01
US10555833B2 (en) 2020-02-11
US9770361B2 (en) 2017-09-26
WO2014179698A3 (en) 2015-02-12
JP2016520383A (ja) 2016-07-14
US10517756B2 (en) 2019-12-31
MX2020006004A (es) 2020-08-17
US9539139B2 (en) 2017-01-10
US20170224534A1 (en) 2017-08-10
US20150038905A1 (en) 2015-02-05
US20250345206A1 (en) 2025-11-13
CN110302004B (zh) 2023-04-28
US10722396B2 (en) 2020-07-28
CN110302004A (zh) 2019-10-08
JP2020014938A (ja) 2020-01-30
SG10201702674PA (en) 2017-06-29
HK1216304A1 (zh) 2016-11-04
EP3417896B1 (en) 2024-01-24
US9937075B2 (en) 2018-04-10
EA201592109A1 (ru) 2016-11-30
JP2018164763A (ja) 2018-10-25
SG11201509051VA (en) 2015-12-30
EP2991706A4 (en) 2016-12-21
CA3121759C (en) 2024-01-02
JP6379183B2 (ja) 2018-08-22
MX2015015282A (es) 2016-02-26
CN105246529B (zh) 2019-06-14
US11559428B2 (en) 2023-01-24
AU2014259694B2 (en) 2018-11-08
WO2014179698A2 (en) 2014-11-06

Similar Documents

Publication Publication Date Title
MX372859B (es) Aparatos y métodos para inyección ocular.
MX395072B (es) Autoinyector de uso unico.
MX2016001281A (es) Dispositivo de inyeccion.
MX2019010543A (es) Insercion de agujas por sobrepresion.
MA40630A (fr) Dispositif d'administration d'un agent thérapeutique muni d'une canule et d'une aiguille pouvant avancer.
AR098076A1 (es) Dispositivo de inyección
AR095988A1 (es) Dispositivo inyector de lente intraocular automatizado
BR112018075456A2 (pt) conjunto de atuador para sistema de administração de fármacos
MX2017004005A (es) Mecanismo de insercion para aguja rigida para una bomba para el suministro de un farmaco.
WO2014145906A3 (en) A prefilled medication device, method of making and using the same
MX374440B (es) Dispositivo de administracion de farmacos.
WO2012049484A3 (en) Injection devices
HK1199414A1 (en) Medicament delivery device with needle assembly removal mechanism
AR095813A1 (es) Dispositivo de inyección
NZ720182A (en) Auto-injector
MX2016010376A (es) Herramienta de auto-inyección con protección de aguja móvil.
EP4434562A3 (en) Medicament delivery device and actuation mechanism for a drug delivery device
MX359960B (es) Aguja de jeringa retráctil mejorada.
HK1220930A1 (zh) 用於药物输送装置的组件及其操作方法
MX2016006670A (es) Dispositivo de administracion de farmacos asistido por resorte.
IN2014KN02290A (https=)
EP4410333A3 (en) Auto-injector device
TR201903181T4 (tr) Güvenli şırınga.
GB2515602A (en) Safety syringe
EA202090623A1 (ru) Вращательно смещаемый механизм введения для помпы подачи лекарства

Legal Events

Date Code Title Description
FG Grant or registration