MX2013014468A - Derivados de oxintomodulina novedosos y composicion farmaceutica para tratar la obesidad que comprende los mismos. - Google Patents
Derivados de oxintomodulina novedosos y composicion farmaceutica para tratar la obesidad que comprende los mismos.Info
- Publication number
- MX2013014468A MX2013014468A MX2013014468A MX2013014468A MX2013014468A MX 2013014468 A MX2013014468 A MX 2013014468A MX 2013014468 A MX2013014468 A MX 2013014468A MX 2013014468 A MX2013014468 A MX 2013014468A MX 2013014468 A MX2013014468 A MX 2013014468A
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutical composition
- same
- peptide
- receptor
- treating obesity
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cell Biology (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a un péptido novedoso que muestra actividades sobre un receptor de péptido similar a glucagón de tipo 1 y un receptor de glucagón, más excelentes que la oxintomodulina nativa, y a una composición para la prevención o el tratamiento de la obesidad que comprende el péptido como un ingrediente activo. Al contrario que la oxintomodulina nativa, el péptido novedoso de la presente invención reduce la ingesta de alimento, suprime el vaciado gástrico y facilita la lipólisis con efectos secundarios reducidos, y muestra también excelentes efectos activadores de receptor. Por tanto, puede usarse ampliamente en el tratamiento de la obesidad con seguridad y eficacia.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20110056472 | 2011-06-10 | ||
PCT/KR2012/004494 WO2012169798A2 (en) | 2011-06-10 | 2012-06-07 | Novel oxyntomodulin derivatives and pharmaceutical composition for treating obesity comprising the same |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013014468A true MX2013014468A (es) | 2014-05-13 |
MX350708B MX350708B (es) | 2017-09-14 |
Family
ID=47296599
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013014468A MX350708B (es) | 2011-06-10 | 2012-06-07 | Derivados de oxintomodulina novedosos y composicion farmaceutica para tratar la obesidad que comprende los mismos. |
MX2022004041A MX2022004041A (es) | 2011-06-10 | 2013-12-09 | Derivados de oxintomodulina novedosos y composicion farmaceutica para tratar la obesidad que comprende los mismos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022004041A MX2022004041A (es) | 2011-06-10 | 2013-12-09 | Derivados de oxintomodulina novedosos y composicion farmaceutica para tratar la obesidad que comprende los mismos. |
Country Status (30)
Country | Link |
---|---|
US (4) | US9527898B2 (es) |
EP (3) | EP3434687B1 (es) |
JP (5) | JP6014127B2 (es) |
KR (2) | KR101502299B1 (es) |
CN (1) | CN103732618B (es) |
AR (1) | AR086866A1 (es) |
AU (4) | AU2012267398B2 (es) |
BR (2) | BR112013031794B1 (es) |
CA (2) | CA3064214C (es) |
CL (1) | CL2013003547A1 (es) |
CY (1) | CY1120781T1 (es) |
DK (3) | DK3878859T3 (es) |
ES (3) | ES2875748T3 (es) |
HR (1) | HRP20181591T1 (es) |
HU (1) | HUE040307T2 (es) |
IL (3) | IL245557B (es) |
LT (1) | LT2718318T (es) |
MX (2) | MX350708B (es) |
MY (1) | MY169309A (es) |
PE (3) | PE20140765A1 (es) |
PL (1) | PL2718318T3 (es) |
PT (1) | PT2718318T (es) |
RS (1) | RS57711B1 (es) |
RU (2) | RU2612906C2 (es) |
SG (2) | SG10201604564XA (es) |
SI (1) | SI2718318T1 (es) |
TW (2) | TWI674271B (es) |
UA (2) | UA114710C2 (es) |
WO (1) | WO2012169798A2 (es) |
ZA (1) | ZA201309054B (es) |
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LT2718318T (lt) | 2011-06-10 | 2018-10-25 | Hanmi Science Co., Ltd. | Nauji oksintomodulino dariniai ir farmacinė kompozicija, apimanti šiuos darinius, nutukimo gydymui |
HUE042585T2 (hu) * | 2011-06-17 | 2019-07-29 | Hanmi Science Co Ltd | Oxintomodulint és immunglobulin-fragmentumot tartalmazó konjugátum és alkalmazása |
MX354705B (es) | 2011-09-23 | 2018-03-16 | Novo Nordisk As | Analogos de glucagon novedosos. |
KR20130049671A (ko) | 2011-11-04 | 2013-05-14 | 한미사이언스 주식회사 | 생리활성 폴리펩타이드 결합체 제조 방법 |
AR090281A1 (es) | 2012-03-08 | 2014-10-29 | Hanmi Science Co Ltd | Proceso mejorado para la preparacion de un complejo polipeptidico fisiologicamente activo |
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