WO2012012891A8 - Compounds, compositions and methods for treatment of arthritis - Google Patents

Compounds, compositions and methods for treatment of arthritis Download PDF

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Publication number
WO2012012891A8
WO2012012891A8 PCT/CA2011/000880 CA2011000880W WO2012012891A8 WO 2012012891 A8 WO2012012891 A8 WO 2012012891A8 CA 2011000880 W CA2011000880 W CA 2011000880W WO 2012012891 A8 WO2012012891 A8 WO 2012012891A8
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
compounds
methods
arthritis
treatment
Prior art date
Application number
PCT/CA2011/000880
Other languages
French (fr)
Other versions
WO2012012891A1 (en
Inventor
Antonio Cruz
Original Assignee
Waratah Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Waratah Pharmaceuticals Inc. filed Critical Waratah Pharmaceuticals Inc.
Publication of WO2012012891A1 publication Critical patent/WO2012012891A1/en
Publication of WO2012012891A8 publication Critical patent/WO2012012891A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to compounds, compositions, formulations and dosage forms comprising N-(Cyclopropylmethyl)-6-phenyl-4-(pyridin-4-yl)pyridazin-3- amine, or a pharmaceutically acceptable salt thereof, and methods for treating arthritis in a subject using such compounds, compositions, formulations and dosage forms.
PCT/CA2011/000880 2010-07-29 2011-07-28 Compounds, compositions and methods for treatment of arthritis WO2012012891A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US36872610P 2010-07-29 2010-07-29
US61/368,726 2010-07-29
US40883810P 2010-11-01 2010-11-01
US61/408,838 2010-11-01

Publications (2)

Publication Number Publication Date
WO2012012891A1 WO2012012891A1 (en) 2012-02-02
WO2012012891A8 true WO2012012891A8 (en) 2012-12-06

Family

ID=45529323

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2011/000880 WO2012012891A1 (en) 2010-07-29 2011-07-28 Compounds, compositions and methods for treatment of arthritis

Country Status (1)

Country Link
WO (1) WO2012012891A1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1812408B1 (en) * 2004-11-02 2013-10-09 Northwestern University Pyridazine compounds, compositions and methods
WO2007127475A2 (en) * 2006-04-28 2007-11-08 Northwestern University Pyridazines for demyelinating diseases and neuropathic pain

Also Published As

Publication number Publication date
WO2012012891A1 (en) 2012-02-02

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