ME03005B - Antagonisti receptora 5-ht3 - Google Patents

Antagonisti receptora 5-ht3

Info

Publication number
ME03005B
ME03005B MEP-2018-89A MEP201889A ME03005B ME 03005 B ME03005 B ME 03005B ME P201889 A MEP201889 A ME P201889A ME 03005 B ME03005 B ME 03005B
Authority
ME
Montenegro
Prior art keywords
receptor antagonists
antagonists
receptor
Prior art date
Application number
MEP-2018-89A
Other languages
German (de)
English (en)
French (fr)
Unknown language (me)
Inventor
Stephen Hitchcock
Holger Monenschein
Holly Reichard
Huikai Sun
Shota Kikuchi
Todd Macklin
Maria Hopkins
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48877569&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME03005(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of ME03005B publication Critical patent/ME03005B/me

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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
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    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
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    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Chemical & Material Sciences (AREA)
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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
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  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MEP-2018-89A 2012-07-17 2013-07-16 Antagonisti receptora 5-ht3 ME03005B (me)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261672709P 2012-07-17 2012-07-17
US201261708521P 2012-10-01 2012-10-01
PCT/US2013/050746 WO2014014951A1 (en) 2012-07-17 2013-07-16 5-ht3 receptor antagonists
EP13742355.4A EP2875011B1 (en) 2012-07-17 2013-07-16 5-ht3 receptor antagonists

Publications (1)

Publication Number Publication Date
ME03005B true ME03005B (me) 2018-10-20

Family

ID=48877569

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2018-89A ME03005B (me) 2012-07-17 2013-07-16 Antagonisti receptora 5-ht3

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US (8) US9012447B2 (enEXAMPLES)
EP (3) EP3312169B1 (enEXAMPLES)
JP (5) JP5816400B2 (enEXAMPLES)
KR (1) KR102148969B1 (enEXAMPLES)
CN (2) CN106478662B (enEXAMPLES)
AP (1) AP2015008240A0 (enEXAMPLES)
AR (1) AR091781A1 (enEXAMPLES)
AU (1) AU2013290375B2 (enEXAMPLES)
BR (1) BR112015001028B1 (enEXAMPLES)
CA (1) CA2879115C (enEXAMPLES)
CL (1) CL2015000121A1 (enEXAMPLES)
CO (1) CO7280468A2 (enEXAMPLES)
CR (1) CR20150057A (enEXAMPLES)
CY (1) CY1120881T1 (enEXAMPLES)
DK (2) DK3312169T3 (enEXAMPLES)
DO (1) DOP2015000009A (enEXAMPLES)
EA (1) EA025986B1 (enEXAMPLES)
EC (1) ECSP15004780A (enEXAMPLES)
ES (2) ES2897881T3 (enEXAMPLES)
GE (1) GEP201606526B (enEXAMPLES)
HR (1) HRP20180523T1 (enEXAMPLES)
HU (2) HUE038757T2 (enEXAMPLES)
IL (1) IL236702B (enEXAMPLES)
IN (1) IN2015DN00957A (enEXAMPLES)
JO (1) JOP20130213B1 (enEXAMPLES)
LT (1) LT2875011T (enEXAMPLES)
ME (1) ME03005B (enEXAMPLES)
MX (1) MX359733B (enEXAMPLES)
MY (1) MY182432A (enEXAMPLES)
NZ (1) NZ704814A (enEXAMPLES)
PE (1) PE20150671A1 (enEXAMPLES)
PH (1) PH12015500085A1 (enEXAMPLES)
PL (2) PL3312169T3 (enEXAMPLES)
PT (2) PT3312169T (enEXAMPLES)
RS (1) RS57096B1 (enEXAMPLES)
SG (1) SG11201500302UA (enEXAMPLES)
SI (1) SI2875011T1 (enEXAMPLES)
SM (1) SMT201800177T1 (enEXAMPLES)
TN (1) TN2015000018A1 (enEXAMPLES)
TW (1) TWI602821B (enEXAMPLES)
UY (1) UY34912A (enEXAMPLES)
WO (2) WO2014014962A1 (enEXAMPLES)
ZA (1) ZA201500781B (enEXAMPLES)

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JOP20130213B1 (ar) * 2012-07-17 2021-08-17 Takeda Pharmaceuticals Co معارضات لمستقبلht3-5
NZ723671A (en) * 2014-03-06 2017-05-26 Shanghai Haiyan Pharmaceutical Tech Co Ltd Piperidine derivatives as orexin receptor antagonist
PT3201203T (pt) 2014-09-29 2021-08-09 Takeda Pharmaceuticals Co Forma cristalina de 1-(1-metil-1h-pirazol-4-il)-n-((1r,5s,7s)-9-metil-3-oxa-9-azabiciclo[3.3.1]nonan-7-il)-1hindol-3-carboxamida
ES2764660T3 (es) 2014-12-16 2020-06-04 Axovant Sciences Gmbh Compuestos de amida de quinuclidina sustituida geminal como agonistas de receptores alfa-7 nicotínicos de acetilcolina
RU2017145964A (ru) 2015-06-10 2019-07-10 Аксовант Сайенсиз Гмбх Аминобензизоксазольные соединения в качестве агонистов α7-никотиновых ацетилхолиновых рецепторов
US10428062B2 (en) 2015-08-12 2019-10-01 Axovant Sciences Gmbh Geminal substituted aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors
MX389282B (es) * 2017-03-27 2025-03-20 Chase Therapeutics Corp Composiciones y métodos para tratar sinucleinopatías.
CA3097332A1 (en) * 2017-04-24 2018-11-01 Chase Therapeutics Corporation Composition comprising pramipexole and 5ht3 antagonist for treating dep ression
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