EA201590228A1 - Антагонисты 5-ht3 рецептора - Google Patents

Антагонисты 5-ht3 рецептора

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Publication number
EA201590228A1
EA201590228A1 EA201590228A EA201590228A EA201590228A1 EA 201590228 A1 EA201590228 A1 EA 201590228A1 EA 201590228 A EA201590228 A EA 201590228A EA 201590228 A EA201590228 A EA 201590228A EA 201590228 A1 EA201590228 A1 EA 201590228A1
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EA
Eurasian Patent Office
Prior art keywords
receptor
compounds
antagonists
vomiting
neurodegenerative
Prior art date
Application number
EA201590228A
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English (en)
Other versions
EA025986B1 (ru
Inventor
Стефен Хичкок
Холгер Моненскейн
Холли Рейчард
Хойкай Сунь
Шота Кикучи
Тодд Маклин
Мария Хопкинс
Original Assignee
Такеда Фармасьютикал Компани Лимитед
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48877569&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201590228(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Такеда Фармасьютикал Компани Лимитед filed Critical Такеда Фармасьютикал Компани Лимитед
Publication of EA201590228A1 publication Critical patent/EA201590228A1/ru
Publication of EA025986B1 publication Critical patent/EA025986B1/ru

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Abstract

Изобретение предлагает антагонисты 5-НТ3 рецептора формулы (I)которые пригодны для лечения заболеваний, поддающихся лечению путем ингибирования 5-НТ3 рецептора, таких как рвота, боль, лекарственная зависимость, нейродегенеративные и психиатрические расстройства, а также расстройства желудочно-кишечного тракта. Кроме того, предлагаются фармацевтические композиции, которые содержат такие соединения и способы получения таких соединений.
EA201590228A 2012-07-17 2013-07-16 Антагонисты 5-ht3 рецептора EA025986B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261672709P 2012-07-17 2012-07-17
US201261708521P 2012-10-01 2012-10-01
PCT/US2013/050746 WO2014014951A1 (en) 2012-07-17 2013-07-16 5-ht3 receptor antagonists

Publications (2)

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EA201590228A1 true EA201590228A1 (ru) 2015-05-29
EA025986B1 EA025986B1 (ru) 2017-02-28

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Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20130213B1 (ar) * 2012-07-17 2021-08-17 Takeda Pharmaceuticals Co معارضات لمستقبلht3-5
RU2669701C2 (ru) * 2014-03-06 2018-10-15 Шанхай Хайянь Фармасьютикал Текнолоджи Ко. Лтд Производные пиперидина в качестве антагонистов рецептора орексина
PL3201203T3 (pl) * 2014-09-29 2021-11-22 Takeda Pharmaceutical Company Limited Krystaliczna postać 1-(1-metylo-1h-pirazol-4-ilo)-n-((1r,5s,7s)-9-metylo-3-oksa-9-azabicyklo[3.3.1]nonan-7-ylo)-1h-indolo-3-karboksyamidu
JP6612874B2 (ja) 2014-12-16 2019-11-27 アクソファント サイエンシーズ ゲーエムベーハー α７−ニコチン性アセチルコリン受容体のアゴニストとしてのジェミナル置換キヌクリジンアミド化合物
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