MX359733B - Antagonistas del receptor de 5-hidroxitriptamina 3 (5-ht3). - Google Patents

Antagonistas del receptor de 5-hidroxitriptamina 3 (5-ht3).

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Publication number
MX359733B
MX359733B MX2015000783A MX2015000783A MX359733B MX 359733 B MX359733 B MX 359733B MX 2015000783 A MX2015000783 A MX 2015000783A MX 2015000783 A MX2015000783 A MX 2015000783A MX 359733 B MX359733 B MX 359733B
Authority
MX
Mexico
Prior art keywords
receptor antagonists
compounds
receptor
disorders
emesis
Prior art date
Application number
MX2015000783A
Other languages
English (en)
Other versions
MX2015000783A (es
Inventor
Monenschein Holger
Hitchcock Stephen
Reichard Holly
Sun Huikai
Kikuchi Shota
Macklin Todd
Hopkins Maria
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48877569&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX359733(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of MX2015000783A publication Critical patent/MX2015000783A/es
Publication of MX359733B publication Critical patent/MX359733B/es

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Abstract

La presente invención proporciona antagonistas del receptor de 5-HT3 de la Fórmula (I): que son útiles para el tratamiento de enfermedades tratables mediante la inhibición del receptor de 5-HT3 tales como émesis, dolor, adicción a los fármacos, trastornos neurodegenerativos y psiquiátricos, y trastornos GI. También se proporcionan composiciones farmacéuticas que contienen estos compuestos y procesos para la preparación de los compuestos.
MX2015000783A 2012-07-17 2013-07-16 Antagonistas del receptor de 5-hidroxitriptamina 3 (5-ht3). MX359733B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261672709P 2012-07-17 2012-07-17
US201261708521P 2012-10-01 2012-10-01
PCT/US2013/050746 WO2014014951A1 (en) 2012-07-17 2013-07-16 5-ht3 receptor antagonists

Publications (2)

Publication Number Publication Date
MX2015000783A MX2015000783A (es) 2015-05-07
MX359733B true MX359733B (es) 2018-10-09

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ID=48877569

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MX2015000783A MX359733B (es) 2012-07-17 2013-07-16 Antagonistas del receptor de 5-hidroxitriptamina 3 (5-ht3).

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JP (5) JP5816400B2 (es)
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CL (1) CL2015000121A1 (es)
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JOP20130213B1 (ar) * 2012-07-17 2021-08-17 Takeda Pharmaceuticals Co معارضات لمستقبلht3-5
SG11201607183PA (en) * 2014-03-06 2016-10-28 Shanghai Haiyan Pharmaceutical Technology Co Ltd Piperidine derivatives as orexin receptor antagonist
US10329306B2 (en) * 2014-09-29 2019-06-25 Takeda Pharmaceutical Company Limited Crystalline form of 1-(1-methyl-1H-pyrazol-4-yl)-N-((IR,5S,7S)-9-methyl-3-oxa-9-azabicyclo[3.3.1]nonan-7-yl)-1H-indole-3-carboxamide
EP3623371A1 (en) 2014-12-16 2020-03-18 Axovant Sciences GmbH Geminal substituted quinuclidine amide compounds as agonists of alpha-7 nicotinic acetylcholine receptors
WO2016201096A1 (en) 2015-06-10 2016-12-15 Forum Pharmaceuticals, Inc. Aminobenzisoxazole compounds as agonists of a7-nicotinic acetylcholine receptors
US10428062B2 (en) 2015-08-12 2019-10-01 Axovant Sciences Gmbh Geminal substituted aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors
AU2018243718A1 (en) * 2017-03-27 2019-11-07 Chase Therapeutics Corporation Compositions and methods for treating synucleinopathies
CA3097332A1 (en) * 2017-04-24 2018-11-01 Chase Therapeutics Corporation Composition comprising pramipexole and 5ht3 antagonist for treating dep ression
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