WO1981001145A1
(en)
|
1979-10-18 |
1981-04-30 |
Univ Illinois |
Hydrolytic enzyme-activatible pro-drugs
|
US5179017A
(en)
|
1980-02-25 |
1993-01-12 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US4634665A
(en)
|
1980-02-25 |
1987-01-06 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US4475196A
(en)
|
1981-03-06 |
1984-10-02 |
Zor Clair G |
Instrument for locating faults in aircraft passenger reading light and attendant call control system
|
US4447233A
(en)
|
1981-04-10 |
1984-05-08 |
Parker-Hannifin Corporation |
Medication infusion pump
|
US5144011A
(en)
|
1981-06-26 |
1992-09-01 |
Boston University |
Acidity-sensitive spacer molecule to control the release of pharmaceuticals from molecular carriers
|
US4631190A
(en)
|
1981-06-26 |
1986-12-23 |
Shen Wei C |
Acidity-sensitive spacer molecule to control the release of pharmaceuticals from molecular carriers
|
US4439196A
(en)
|
1982-03-18 |
1984-03-27 |
Merck & Co., Inc. |
Osmotic drug delivery system
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
US4447224A
(en)
|
1982-09-20 |
1984-05-08 |
Infusaid Corporation |
Variable flow implantable infusion apparatus
|
US4487603A
(en)
|
1982-11-26 |
1984-12-11 |
Cordis Corporation |
Implantable microinfusion pump system
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US4486194A
(en)
|
1983-06-08 |
1984-12-04 |
James Ferrara |
Therapeutic device for administering medicaments through the skin
|
EP0154316B1
(en)
|
1984-03-06 |
1989-09-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified lymphokine and production thereof
|
US4698420A
(en)
|
1985-02-25 |
1987-10-06 |
Xoma Corporation |
Antibody hybrid molecules and process for their preparation
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
US5374548A
(en)
|
1986-05-02 |
1994-12-20 |
Genentech, Inc. |
Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor
|
MX9203291A
(es)
|
1985-06-26 |
1992-08-01 |
Liposome Co Inc |
Metodo para acoplamiento de liposomas.
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
US4954617A
(en)
|
1986-07-07 |
1990-09-04 |
Trustees Of Dartmouth College |
Monoclonal antibodies to FC receptors for immunoglobulin G on human mononuclear phagocytes
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
US5260203A
(en)
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
US4881175A
(en)
|
1986-09-02 |
1989-11-14 |
Genex Corporation |
Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
|
AU600575B2
(en)
|
1987-03-18 |
1990-08-16 |
Sb2, Inc. |
Altered antibodies
|
US5013653A
(en)
|
1987-03-20 |
1991-05-07 |
Creative Biomolecules, Inc. |
Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage
|
WO1988009344A1
(en)
|
1987-05-21 |
1988-12-01 |
Creative Biomolecules, Inc. |
Targeted multifunctional proteins
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
US5091513A
(en)
|
1987-05-21 |
1992-02-25 |
Creative Biomolecules, Inc. |
Biosynthetic antibody binding sites
|
US5132405A
(en)
|
1987-05-21 |
1992-07-21 |
Creative Biomolecules, Inc. |
Biosynthetic antibody binding sites
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
US5677425A
(en)
|
1987-09-04 |
1997-10-14 |
Celltech Therapeutics Limited |
Recombinant antibody
|
GB8809129D0
(en)
|
1988-04-18 |
1988-05-18 |
Celltech Ltd |
Recombinant dna methods vectors and host cells
|
US5476996A
(en)
|
1988-06-14 |
1995-12-19 |
Lidak Pharmaceuticals |
Human immune system in non-human animal
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
KR0184860B1
(ko)
|
1988-11-11 |
1999-04-01 |
메디칼 리써어치 카운실 |
단일영역 리간드와 이를 포함하는 수용체 및 이들의 제조방법과 이용(법)
|
DE68925966T2
(de)
|
1988-12-22 |
1996-08-29 |
Kirin Amgen Inc |
Chemisch modifizierte granulocytenkolonie erregender faktor
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
US5108921A
(en)
|
1989-04-03 |
1992-04-28 |
Purdue Research Foundation |
Method for enhanced transmembrane transport of exogenous molecules
|
US6291158B1
(en)
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for tapping the immunological repertoire
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
ATE356869T1
(de)
|
1990-01-12 |
2007-04-15 |
Amgen Fremont Inc |
Bildung von xenogenen antikörpern
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
US6261774B1
(en)
|
1990-06-11 |
2001-07-17 |
Gilead Sciences, Inc. |
Truncation selex method
|
US5712375A
(en)
|
1990-06-11 |
1998-01-27 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US5763566A
(en)
|
1990-06-11 |
1998-06-09 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue SELEX
|
US5789157A
(en)
|
1990-06-11 |
1998-08-04 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US5864026A
(en)
|
1990-06-11 |
1999-01-26 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
ES2246502T3
(es)
|
1990-08-29 |
2006-02-16 |
Genpharm International, Inc. |
Animales no humanos transgenicos capaces de producir anticuerpos heterologos.
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
WO1994025585A1
(en)
|
1993-04-26 |
1994-11-10 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
EP0616640B1
(en)
|
1991-12-02 |
2004-09-01 |
Medical Research Council |
Production of anti-self antibodies from antibody segment repertoires and displayed on phage
|
DE69233745D1
(de)
|
1991-12-02 |
2008-10-23 |
Cambridge Antibody Tech |
Herstellung von Autoantikörpern auf Phagenoberflächen ausgehend von Antikörpersegmentbibliotheken
|
EP0746609A4
(en)
|
1991-12-17 |
1997-12-17 |
Genpharm Int |
NON-HUMAN TRANSGENIC ANIMALS CAPABLE OF PRODUCING HETEROLOGOUS ANTIBODIES
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
EP0640094A1
(en)
|
1992-04-24 |
1995-03-01 |
The Board Of Regents, The University Of Texas System |
Recombinant production of immunoglobulin-like domains in prokaryotic cells
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
US6765087B1
(en)
|
1992-08-21 |
2004-07-20 |
Vrije Universiteit Brussel |
Immunoglobulins devoid of light chains
|
GB9223377D0
(en)
|
1992-11-04 |
1992-12-23 |
Medarex Inc |
Humanized antibodies to fc receptors for immunoglobulin on human mononuclear phagocytes
|
DE69427974T2
(de)
|
1993-04-29 |
2001-12-06 |
Unilever N.V., Rotterdam |
Herstellung von antikörpern oder funktionstüchtig gemachten teilen davon, abgeleitet von schweren ketten von immunglobulinen von camelidae
|
US6214345B1
(en)
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
EP0714409A1
(en)
|
1993-06-16 |
1996-06-05 |
Celltech Therapeutics Limited |
Antibodies
|
US5625825A
(en)
|
1993-10-21 |
1997-04-29 |
Lsi Logic Corporation |
Random number generating apparatus for an interface unit of a carrier sense with multiple access and collision detect (CSMA/CD) ethernet data network
|
SE9400088D0
(sv)
|
1994-01-14 |
1994-01-14 |
Kabi Pharmacia Ab |
Bacterial receptor structures
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
US6013443A
(en)
|
1995-05-03 |
2000-01-11 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue SELEX
|
DE69633227T2
(de)
|
1995-05-03 |
2005-09-15 |
Gilead Sciences, Inc., Foster City |
Systematische evoultion von liganden durch exponentielle anreicherung: gewebe-selex
|
WO1997012862A1
(en)
|
1995-10-03 |
1997-04-10 |
The Scripps Research Institute |
Cbi analogs of cc-1065 and the duocarmycins
|
US6642360B2
(en)
|
1997-12-03 |
2003-11-04 |
Genentech, Inc. |
Secreted polypeptides that stimulate release of proteoglycans from cartilage
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
US7411051B2
(en)
|
1997-03-07 |
2008-08-12 |
Human Genome Sciences, Inc. |
Antibodies to HDPPA04 polypeptide
|
US7368531B2
(en)
|
1997-03-07 |
2008-05-06 |
Human Genome Sciences, Inc. |
Human secreted proteins
|
DE69833755T2
(de)
|
1997-05-21 |
2006-12-28 |
Biovation Ltd. |
Verfahren zur herstellung von nicht-immunogenen proteinen
|
DE69825048D1
(de)
|
1997-05-22 |
2004-08-19 |
Scripps Research Inst |
Analoga von duocarmycin and cc-1065
|
DE19742706B4
(de)
|
1997-09-26 |
2013-07-25 |
Pieris Proteolab Ag |
Lipocalinmuteine
|
GB9722131D0
(en)
|
1997-10-20 |
1997-12-17 |
Medical Res Council |
Method
|
NZ527898A
(en)
|
1997-12-03 |
2005-01-28 |
Genentech Inc |
PRO347 polypeptides and nucleic acids encoding proteins with homology to cysteine-rich secretory protein-3
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
PT2180007E
(pt)
|
1998-04-20 |
2013-11-25 |
Roche Glycart Ag |
Engenharia de glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos
|
EP1077991A1
(en)
|
1998-05-07 |
2001-02-28 |
Genetics Institute, Inc. |
Secreted proteins and polynucleotides encoding them
|
IL140937A0
(en)
|
1998-08-07 |
2002-02-10 |
Immunex Corp |
Molecules designated ldcam
|
ATE415480T1
(de)
|
1998-08-07 |
2008-12-15 |
Immunex Corp |
B7l-1 moleküle
|
JP2002530062A
(ja)
|
1998-10-28 |
2002-09-17 |
ヒューマン ジノーム サイエンシーズ, インコーポレイテッド |
12個のヒト分泌タンパク質
|
US20030055231A1
(en)
|
1998-10-28 |
2003-03-20 |
Jian Ni |
12 human secreted proteins
|
WO2000028032A2
(en)
|
1998-11-12 |
2000-05-18 |
Incyte Pharmaceuticals, Inc. |
Human cell surface receptor proteins
|
JP2003524387A
(ja)
|
1998-12-01 |
2003-08-19 |
ジェネンテック・インコーポレーテッド |
分泌及び膜貫通ポリペプチドとそれをコードする核酸
|
CA2359067C
(en)
|
1999-01-15 |
2017-03-14 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
AU764092B2
(en)
|
1999-03-23 |
2003-08-07 |
Genentech Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
EP2270147B2
(en)
|
1999-04-09 |
2020-07-22 |
Kyowa Kirin Co., Ltd. |
Method for controlling the activity of immunologically functional molecule
|
US7129338B1
(en)
|
1999-07-08 |
2006-10-31 |
Research Association For Biotechnology |
Secretory protein or membrane protein
|
US6387620B1
(en)
|
1999-07-28 |
2002-05-14 |
Gilead Sciences, Inc. |
Transcription-free selex
|
NZ517372A
(en)
|
1999-07-29 |
2004-04-30 |
Medarex Inc |
Human monoclonal antibodies to HER2/neu
|
NZ517202A
(en)
|
1999-08-24 |
2004-05-28 |
Medarex Inc |
Human CTLA-4 antibodies and their uses
|
AU6802801A
(en)
|
2000-03-01 |
2001-09-24 |
Genentech Inc |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
WO2002014577A1
(fr)
*
|
2000-08-04 |
2002-02-21 |
Japan Lifeline Co., Ltd |
Procede pour produire un element metallique cylindrique a paroi mince
|
AU2001286514A1
(en)
|
2000-08-15 |
2002-02-25 |
National Cancer Center Research Institute |
Diagnosis and treatment of tumor-suppressor associated disorders
|
WO2002018424A2
(en)
|
2000-09-01 |
2002-03-07 |
Hyseq, Inc. |
Nucleic acids and polypeptides
|
WO2002020565A2
(en)
|
2000-09-08 |
2002-03-14 |
Universität Zürich |
Collections of repeat proteins comprising repeat modules
|
US20020157122A1
(en)
*
|
2000-10-27 |
2002-10-24 |
Wong Philip C. |
Beta-secretase transgenic organisms, anti-beta-secretase antibodies, and methods of use thereof
|
WO2002066643A2
(en)
|
2000-11-13 |
2002-08-29 |
Curagen Corporation |
Proteins, polynucleotides encoding them and methods of using the same
|
PT1354034E
(pt)
|
2000-11-30 |
2008-02-28 |
Medarex Inc |
Roedores transgénicos transcromossómicos para produção de anticorpos humanos
|
US20050053973A1
(en)
|
2001-04-26 |
2005-03-10 |
Avidia Research Institute |
Novel proteins with targeted binding
|
US20030082630A1
(en)
|
2001-04-26 |
2003-05-01 |
Maxygen, Inc. |
Combinatorial libraries of monomer domains
|
US20050089932A1
(en)
|
2001-04-26 |
2005-04-28 |
Avidia Research Institute |
Novel proteins with targeted binding
|
US20060223114A1
(en)
|
2001-04-26 |
2006-10-05 |
Avidia Research Institute |
Protein scaffolds and uses thereof
|
US20050048512A1
(en)
|
2001-04-26 |
2005-03-03 |
Avidia Research Institute |
Combinatorial libraries of monomer domains
|
US20030157561A1
(en)
|
2001-11-19 |
2003-08-21 |
Kolkman Joost A. |
Combinatorial libraries of monomer domains
|
US20040175756A1
(en)
|
2001-04-26 |
2004-09-09 |
Avidia Research Institute |
Methods for using combinatorial libraries of monomer domains
|
KR100583331B1
(ko)
|
2001-05-11 |
2006-05-26 |
기린 비루 가부시키가이샤 |
인간 항체 λ 경쇄 유전자를 포함하는 인간 인공 염색체 및 자손 전달 가능한 상기 인간 인공 염색체를 포함하는 비인간 동물
|
EP1421203A4
(en)
|
2001-05-17 |
2005-06-01 |
Diversa Corp |
NEW ANTIGEN-BINDING MOLECULES FOR THERAPEUTIC, DIAGNOSTIC, PROPHYLACTIC, ENZYMATIC, INDUSTRIAL AND AGRICULTURAL APPLICATIONS AND METHOD FOR THE PRODUCTION AND SCREENING THEREOF
|
WO2002096910A1
(en)
|
2001-05-31 |
2002-12-05 |
Medarex, Inc. |
Cytotoxins, prodrugs, linkers and stabilizers useful therefor
|
WO2002100353A2
(en)
|
2001-06-11 |
2002-12-19 |
Medarex, Inc. |
Cd10-activated prodrug compounds
|
JP4303105B2
(ja)
|
2001-06-28 |
2009-07-29 |
ドマンティス リミテッド |
二重特異性リガンドとその利用
|
CA2459308A1
(en)
|
2001-09-07 |
2003-03-20 |
Dale L. Boger |
Cbi analogues of cc-1065 and the duocarmycins
|
US7091186B2
(en)
|
2001-09-24 |
2006-08-15 |
Seattle Genetics, Inc. |
p-Amidobenzylethers in drug delivery agents
|
HUP0600342A3
(en)
|
2001-10-25 |
2011-03-28 |
Genentech Inc |
Glycoprotein compositions
|
AU2003217912A1
(en)
|
2002-03-01 |
2003-09-16 |
Xencor |
Antibody optimization
|
BR0309145A
(pt)
|
2002-04-09 |
2005-02-01 |
Kyowa Hakko Kogyo Kk |
Células das quais o genoma é modificado
|
ES2263984T3
(es)
|
2002-06-28 |
2006-12-16 |
Domantis Limited |
Ligandos doble-especificos con una vida media serica aumentada.
|
EP1558650A2
(en)
|
2002-11-08 |
2005-08-03 |
Ablynx N.V. |
Camelidae antibodies against immunoglobulin e and use thereof for the treatment of allergic disorders
|
AU2003290330A1
(en)
|
2002-12-27 |
2004-07-22 |
Domantis Limited |
Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand
|
CA2516128A1
(en)
|
2003-02-14 |
2004-09-02 |
Sagres Discovery, Inc. |
Therapeutic targets in cancer
|
ATE382099T1
(de)
|
2003-03-31 |
2008-01-15 |
Stichting Res Fonds Pathologie |
Nachweis von invasivem krebs induziert von hpv und dessen vorläufer läsionen mit invasionspotential
|
DE10316701A1
(de)
|
2003-04-09 |
2004-11-04 |
Hinzmann, Bernd, Dr. |
Humane Nukleinsäuresequenzen aus Bronchialkarzinomen
|
ES2340494T3
(es)
|
2003-04-15 |
2010-06-04 |
Glaxosmithkline Llc |
Mutantes de sustitucion de il-18 humana y sus conjugados.
|
AU2004239065B2
(en)
|
2003-05-14 |
2008-05-15 |
Domantis Limited |
A process for recovering polypeptides that unfold reversibly from a polypeptide repertoire
|
CN1845938B
(zh)
|
2003-06-30 |
2010-05-26 |
杜门蒂斯有限公司 |
多肽
|
CA2533512C
(en)
|
2003-07-25 |
2013-06-11 |
Amgen Inc. |
Antagonists and agonists of ldcam and methods of use
|
US7807392B1
(en)
|
2003-09-15 |
2010-10-05 |
Celera Corporation |
Lung disease targets and uses thereof
|
EP1675878A2
(en)
|
2003-10-24 |
2006-07-05 |
Avidia, Inc. |
Ldl receptor class a and egf domain monomers and multimers
|
JP4227881B2
(ja)
|
2003-11-13 |
2009-02-18 |
財団法人宮崎県産業支援財団 |
成人t細胞白血病診断薬
|
WO2005082023A2
(en)
|
2004-02-23 |
2005-09-09 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
EP1747021B1
(en)
|
2004-05-19 |
2015-09-09 |
E. R. Squibb & Sons, L.L.C. |
Self-immolative linkers and drug conjugates
|
RU2402548C2
(ru)
|
2004-05-19 |
2010-10-27 |
Медарекс, Инк. |
Химические линкеры и их конъюгаты
|
US7541330B2
(en)
|
2004-06-15 |
2009-06-02 |
Kosan Biosciences Incorporated |
Conjugates with reduced adverse systemic effects
|
US20060008844A1
(en)
|
2004-06-17 |
2006-01-12 |
Avidia Research Institute |
c-Met kinase binding proteins
|
EP3088004B1
(en)
|
2004-09-23 |
2018-03-28 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
CA2584297A1
(en)
|
2004-10-29 |
2006-05-11 |
Genentech, Inc. |
Disruptions of genes encoding secreted proteins, compositions and methods relating thereto
|
JP2008520207A
(ja)
|
2004-11-16 |
2008-06-19 |
アヴィディア リサーチ インスティテュート |
タンパク質骨格およびその使用
|
EP1844073A1
(en)
|
2005-01-31 |
2007-10-17 |
Ablynx N.V. |
Method for generating variable domain sequences of heavy chain antibodies
|
EP1860119B1
(en)
*
|
2005-02-28 |
2011-08-03 |
Institute for Antibodies Co., Ltd. |
ANTI-IgSF4 ANTIBODY AND UTILIZATION OF THE SAME
|
US7608413B1
(en)
|
2005-03-25 |
2009-10-27 |
Celera Corporation |
Kidney disease targets and uses thereof
|
US7714016B2
(en)
|
2005-04-08 |
2010-05-11 |
Medarex, Inc. |
Cytotoxic compounds and conjugates with cleavable substrates
|
JP4536588B2
(ja)
|
2005-05-11 |
2010-09-01 |
財団法人宮崎県産業支援財団 |
成人t細胞白血病の診断器具
|
US7842467B1
(en)
|
2005-05-12 |
2010-11-30 |
Celera Corporation |
Breast disease targets and uses thereof
|
JP5131946B2
(ja)
|
2005-09-13 |
2013-01-30 |
国立大学法人 東京大学 |
がんの診断、処置および/または予防、および/または浸潤・転移の抑制のための方法、システムおよび組成物ならびに関連するスクリーニング方法
|
CA2623652C
(en)
|
2005-09-26 |
2013-11-26 |
Medarex, Inc. |
Antibody-drug conjugates and methods of use
|
US20070191272A1
(en)
|
2005-09-27 |
2007-08-16 |
Stemmer Willem P |
Proteinaceous pharmaceuticals and uses thereof
|
WO2007051081A1
(en)
|
2005-10-26 |
2007-05-03 |
Medarex, Inc. |
Methods and compounds for preparing cc-1065 analogs
|
CA2627190A1
(en)
|
2005-11-10 |
2007-05-24 |
Medarex, Inc. |
Duocarmycin derivatives as novel cytotoxic compounds and conjugates
|
US10155816B2
(en)
|
2005-11-28 |
2018-12-18 |
Genmab A/S |
Recombinant monovalent antibodies and methods for production thereof
|
WO2007074832A1
(ja)
|
2005-12-28 |
2007-07-05 |
Japan Health Sciences Foundation |
小細胞肺がんの診断のための方法、システムおよび組成物ならびに関連するスクリーニング方法
|
US7842291B1
(en)
|
2006-05-22 |
2010-11-30 |
Celera Corporation |
Methods and compositions for diagnosing and treating diseases
|
EP2975057A1
(en)
|
2006-07-10 |
2016-01-20 |
Fujita Health University |
Novel anti-cd73 antibody
|
EP2520935A3
(en)
|
2006-08-09 |
2013-02-13 |
Homestead Clinical Corporation |
Organ-specific proteins and methods of their use
|
DK2069793T3
(en)
*
|
2006-08-29 |
2017-04-24 |
Oxford Biotherapeutics Ltd |
IDENTIFICATION OF PROTEIN IN CONNECTION WITH HEPATOCELLULAR CARCINOMA, GLIOBLASTOMA AND LUNG CANCER
|
US8026065B2
(en)
|
2006-11-02 |
2011-09-27 |
Yale University |
Assessment of oocyte competence
|
EP1918299A1
(en)
|
2006-11-03 |
2008-05-07 |
Universite De Geneve |
Modulators of cell adhesion molecules and use thereof
|
TWI412367B
(zh)
|
2006-12-28 |
2013-10-21 |
Medarex Llc |
化學鏈接劑與可裂解基質以及其之綴合物
|
WO2008143639A2
(en)
|
2007-04-06 |
2008-11-27 |
Source Precision Medicine, Inc. |
Gene expression profiling for identification, monitoring, and treatment of cervical cancer
|
US20100150924A1
(en)
|
2007-05-22 |
2010-06-17 |
Elior Peles |
Regulation of myelination by nectin-like (necl) molecules
|
WO2009020645A2
(en)
*
|
2007-08-07 |
2009-02-12 |
Oxford Genome Sciences (Uk) Ltd. |
Matriptase protein and uses thereof
|
WO2009029883A2
(en)
|
2007-08-30 |
2009-03-05 |
Genentech, Inc. |
Methods and compositions for modulating t cells
|
EP2195658A2
(en)
|
2007-09-28 |
2010-06-16 |
Royal College of Surgeons in Ireland |
A method of assessing colorectal cancer status in an individual
|
EP2128259A1
(en)
|
2008-05-27 |
2009-12-02 |
Koninklijke Philips Electronics N.V. |
Therapy delivery and monitoring using a gene of interest-reporter fusion protein and optical imaging
|
US20100190652A1
(en)
|
2009-01-27 |
2010-07-29 |
Srinivasa Nagalla |
Biomarkers for Detection of Neonatal Sepsis in Biological Fluid
|
PL2403878T3
(pl)
*
|
2009-03-05 |
2017-12-29 |
E. R. Squibb & Sons, L.L.C. |
W pełni ludzkie przeciwciała specyficzne dla CADM1
|