MC1805A1 - Tolunitriles substitues par des x-heterocycles - Google Patents

Tolunitriles substitues par des x-heterocycles

Info

Publication number
MC1805A1
MC1805A1 MC871874A MC1874A MC1805A1 MC 1805 A1 MC1805 A1 MC 1805A1 MC 871874 A MC871874 A MC 871874A MC 1874 A MC1874 A MC 1874A MC 1805 A1 MC1805 A1 MC 1805A1
Authority
MC
Monaco
Prior art keywords
alkyl
substd
opt
alkylene
alkylthio
Prior art date
Application number
MC871874A
Other languages
English (en)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25274596&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MC1805(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of MC1805A1 publication Critical patent/MC1805A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Indole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Hydrogenated Pyridines (AREA)
MC871874A 1986-03-07 1987-03-05 Tolunitriles substitues par des x-heterocycles MC1805A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/837,489 US4749713A (en) 1986-03-07 1986-03-07 Alpha-heterocycle substituted tolunitriles

Publications (1)

Publication Number Publication Date
MC1805A1 true MC1805A1 (fr) 1987-12-22

Family

ID=25274596

Family Applications (1)

Application Number Title Priority Date Filing Date
MC871874A MC1805A1 (fr) 1986-03-07 1987-03-05 Tolunitriles substitues par des x-heterocycles

Country Status (36)

Country Link
US (1) US4749713A (fr)
EP (1) EP0236940B3 (fr)
JP (1) JPH0755930B2 (fr)
KR (1) KR910000482B1 (fr)
AT (1) ATE94873T1 (fr)
BG (4) BG45700A3 (fr)
CA (1) CA1316928C (fr)
CY (1) CY1905A (fr)
CZ (3) CZ279027B6 (fr)
DD (1) DD264432A5 (fr)
DE (2) DE3787480T2 (fr)
DK (1) DK172190B1 (fr)
DZ (1) DZ1055A1 (fr)
ES (1) ES2059317T3 (fr)
FI (1) FI91857C (fr)
HK (1) HK50296A (fr)
HU (1) HU202843B (fr)
IE (1) IE61101B1 (fr)
IL (1) IL81746A (fr)
LU (1) LU90128I2 (fr)
LV (1) LV5769B4 (fr)
MA (1) MA20888A1 (fr)
MC (1) MC1805A1 (fr)
MT (1) MTP998B (fr)
MX (1) MX5496A (fr)
MY (1) MY102428A (fr)
NL (1) NL970011I2 (fr)
NO (2) NO170277C (fr)
PH (1) PH24159A (fr)
PL (2) PL151490B1 (fr)
PT (1) PT84410B (fr)
RO (2) RO101532B1 (fr)
SK (3) SK279102B6 (fr)
SU (3) SU1470184A3 (fr)
TN (1) TNSN87033A1 (fr)
ZA (1) ZA871637B (fr)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
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US5352795A (en) * 1986-03-07 1994-10-04 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US5112845A (en) * 1986-03-07 1992-05-12 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
GB8714013D0 (en) * 1987-06-16 1987-07-22 Ici Plc (substituted-aralkyl)heterocyclic compounds
DE3811574A1 (de) * 1988-03-31 1989-10-19 Schering Ag N-substituierte imidazole, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
DE59010171D1 (de) * 1989-07-14 1996-04-11 Ciba Geigy Ag Substituierte Benzonitrile
DE3926365A1 (de) * 1989-08-04 1991-02-07 Schering Ag Cycloalkylenazole, verfahren zu deren herstellung, pharmazeutische praeparate, die diese enthalten sowie ihre verwendung zur herstellung von arzneimitteln
JP2602456B2 (ja) * 1990-04-12 1997-04-23 雪印乳業株式会社 子宮内膜症治療剤
EP0457716A1 (fr) * 1990-04-20 1991-11-21 Ciba-Geigy Ag Dérivés de naphtaline
DE4039559A1 (de) * 1990-12-07 1992-06-11 Schering Ag Funktionalisierte vinylazole, verfahren zu deren herstellung, pharmazeutische praeparate die diese vinylazole enthalten sowie deren verwendung zur herstellung von arzneimitteln
TW210334B (fr) * 1990-12-12 1993-08-01 Ciba Geigy Ag
CH683151A5 (de) * 1991-04-24 1994-01-31 Ciba Geigy Ag Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
DE4120107A1 (de) * 1991-06-14 1992-12-17 Schering Ag Bicyclisch substituierte vinylimidazole, -triazole und -tetrazole
WO1993005027A1 (fr) 1991-09-02 1993-03-18 Yamanouchi Pharmaceutical Co., Ltd. Amine tertiaire triazolylee ou un sel de celle-ci
US5223539A (en) * 1991-11-22 1993-06-29 G. D. Searle & Co. N,n-di-alkyl(phenoxy)benzamide derivatives
AU5285593A (en) * 1992-10-21 1994-05-09 Sankyo Company Limited Azole compound
GB2273704B (en) * 1992-12-16 1997-01-22 Orion Yhtymae Oy Triazolyl diaryl selective aromatase inhibiting compounds
US5426196A (en) * 1993-12-22 1995-06-20 Glaxo Inc. Synthesis of diaryl methanes
EP0877610A4 (fr) * 1996-01-30 1999-09-15 Merck & Co Inc Inhibiteurs de farnesyl-proteine transferase
JP2000504014A (ja) * 1996-01-30 2000-04-04 メルク エンド カンパニー インコーポレーテッド ファルネシル―タンパク質転移酵素の阻害剤
CA2249615A1 (fr) * 1996-04-03 1997-10-09 Robert Gomez Inhibiteurs de la farnesyl-proteine transferase
EP0891360A4 (fr) * 1996-04-03 2002-05-15 Merck & Co Inc Inhibiteurs de la farnesyl-proteine transferase
US6063930A (en) * 1996-04-03 2000-05-16 Merck & Co., Inc. Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
US6080870A (en) * 1996-04-03 2000-06-27 Merck & Co., Inc. Biaryl substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
CZ299756B6 (cs) 2001-05-16 2008-11-12 Novartis Ag Kombinace s obsahem N-{5-[4-(4-methyl-piperazino-methyl)benzoylamido]-2-methylfenyl}-4-(3-pyridyl)-2-pyrimidin-aminu k lécení proliferativních onemocnení
BR0214868A (pt) * 2001-12-11 2004-12-14 Emory Universsity Bis-(cianofenil) metil-triazol para uso em prevenção de câncer de mama
ATE345790T1 (de) * 2002-07-30 2006-12-15 Novartis Pharma Gmbh Kombination von einem aromatasehemmer mit einem bisphosphonat
GB0217636D0 (en) * 2002-07-30 2002-09-11 Novartis Ag Organic compounds
JP2004196795A (ja) * 2002-12-16 2004-07-15 Wyeth 外部寄生虫駆除剤としてのｎ−フェニル−３−シクロプロピルピラゾール−４−カルボニトリル
WO2005047269A1 (fr) * 2003-11-14 2005-05-26 Natco Pharma Limited Procede de separation du precurseur de 4- 1-(1,2,4-triazolyl) methyl!benzonitrile et de son isomere 1,3,4-triazolyle
MXPA06006837A (es) * 2003-12-15 2006-09-04 Theramex Derivados de 1-n-fenil-amino-ih-imidazol y composiciones farmaceuticas que los contienen.
CA2608904A1 (fr) * 2005-07-06 2007-09-07 Sicor Inc. Procede ameliore de fabrication de letrozole
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US20090082413A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched letrozole
JP2013525296A (ja) 2010-04-16 2013-06-20 ノバルティス アーゲー 内分泌療法抵抗性乳癌の処置
WO2012025762A2 (fr) 2010-08-27 2012-03-01 Generics [Uk] Limited Intermédiaire pur
PT2753312T (pt) * 2011-09-08 2017-02-03 Mereo Biopharma 2 Ltd Utilização de um inibidor da aromatase para o tratamento de hipogonadismo e doenças relacionadas
SG10201706196XA (en) 2012-06-08 2017-08-30 Hoffmann La Roche Mutant selectivity and combinations of a phosphoinositide 3 kinase inhibitor compound and chemotherapeutic agents for the treatment of cancer
EP3033086B1 (fr) 2013-08-14 2021-09-22 Novartis AG Thérapie de combinaison pour le traitement du cancer
AR104068A1 (es) 2015-03-26 2017-06-21 Hoffmann La Roche Combinaciones de un compuesto inhibidor de fosfoinosítido 3-cinasa y un compuesto inhibidor de cdk4/6 para el tratamiento del cáncer
GB201614179D0 (en) 2016-08-19 2016-10-05 Mereo Biopharma 2 Ltd Dosage regimen for the treatment of endometriosis
WO2020023297A1 (fr) 2018-07-23 2020-01-30 Genentech, Inc. Méthodes de traitement du cancer avec un inhibiteur de pi3k, le gdc-0077
EP3863618A1 (fr) 2018-10-08 2021-08-18 F. Hoffmann-La Roche AG Méthodes de traitement du cancer avec des inhibiteurs de pi3k alpha et de la metformine
TW202133857A (zh) 2019-12-03 2021-09-16 美商建南德克公司 用於乳癌治療之組合療法
JP2024501445A (ja) 2020-12-11 2024-01-12 ジェネンテック， インコーポレイテッド Ｈｅｒ２がんの処置のための併用療法

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US3290281A (en) * 1963-07-18 1966-12-06 Weinstein Julius Photochromic nitrobenzylpyridines
US3397273A (en) * 1966-02-18 1968-08-13 Lilly Co Eli Controlling phytopathogenic fungi on plants with 3-pyridyl methane derivatives
GB1170188A (en) * 1967-09-15 1969-11-12 Bayer Ag N-trityl-imidazoles and salts and uses thereof
DE1670976B2 (de) * 1968-01-29 1976-07-22 N-trityl-imidazole
DE1908991B2 (de) * 1969-02-22 1977-05-26 Bayer Ag, 5090 Leverkusen Alpha, alpha-disubstituierte n- benzylimidazole und deren salze
BR6915465D0 (pt) * 1969-03-07 1973-01-04 Bayer Ag Processo para preparar n-benzimidazois substituidos na posicao alfa por heterociclos penta-membrados com atividade antimicotica
DE2007794A1 (de) * 1970-02-20 1971-09-02 Farbenfabriken Bayer Aktiengesell schaft, 5090 Leverkusen Fungizide Mittel
DE2009020C3 (de) * 1970-02-26 1979-09-13 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von N-(l,l,l-trisubstituierten)-Methylazolen
US3764690A (en) * 1972-03-03 1973-10-09 Bayer Ag Substituted n-benzylimidazoles as antimycotic agents
US3927017A (en) * 1974-06-27 1975-12-16 Janssen Pharmaceutica Nv 1-({62 -Aryl-{62 -R-ethyl)imidazoles
DE2628152C2 (de) * 1976-06-23 1985-03-28 Bayer Ag, 5090 Leverkusen Fungizide und nematizide Mittel
DE2732531A1 (de) * 1977-07-19 1979-02-01 Hoechst Ag Imidazolcarbonsaeuren und deren derivate
DE2735314A1 (de) * 1977-08-05 1979-02-22 Basf Ag Alpha-azolylsulfide und deren derivate
US4431815A (en) * 1977-08-26 1984-02-14 Burroughs Wellcome Co. 1-[3-(2,4-Dichlorophenyl)propyl]imidazole and salts thereof
DE2862340D1 (en) * 1978-02-01 1983-11-24 Wellcome Found Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof
DE2808086A1 (de) * 1978-02-24 1979-08-30 Bayer Ag Substituierte diphenyl-imidazolyl- methane, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2821829A1 (de) * 1978-05-19 1979-11-22 Basf Ag Mittel zur regulierung des pflanzenwachstums
JPS55313A (en) * 1978-06-13 1980-01-05 Kissei Pharmaceut Co Ltd Imidazole derivative
DE2847441A1 (de) * 1978-11-02 1980-05-22 Basf Ag Imidazol-kupferkomplexverbindungen
DK157860C (da) * 1979-06-07 1990-07-30 Shionogi & Co Analogifremgangsmaade til fremstilling af benzylimidazolderivater samt farmaceutisk acceptable syreadditionssalte deraf
US4281141A (en) * 1980-05-30 1981-07-28 Eli Lilly And Company 3-(Imidazol-4-yl)-2-phenylpropanenitriles
US4617307A (en) * 1984-06-20 1986-10-14 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors
US4562199A (en) * 1983-08-11 1985-12-31 Thorogood Peter B Imidazole derivatives, compositions and use
EP0149976A3 (fr) * 1983-12-30 1986-12-10 Ciba-Geigy Ag Imidazoles substitués
US4755526A (en) * 1984-06-18 1988-07-05 Eli Lilly And Company Method of inhibiting aromatase
US4605661A (en) * 1984-06-18 1986-08-12 Eli Lilly And Company Aromastase inhibiting α,α-diarylimidazole-4(5)-propionitriles, α,α-diarylimidazole-4(5)-propionamides, and 4(5)-(2,2-diarylethyl)imidazoles
US4766140A (en) * 1984-06-18 1988-08-23 Eli Lilly And Company Method of inhibiting aromatase
US4801594A (en) * 1984-06-18 1989-01-31 Eli Lilly And Company Aromatase inhibitors
US4602025A (en) * 1984-06-18 1986-07-22 Eli Lilly And Company Aromatase inhibitors

Also Published As

Publication number Publication date
RO101533B1 (en) 1992-06-25
CY1905A (en) 1987-03-05
CS8707367A2 (en) 1991-02-12
HU202843B (en) 1991-04-29
HUT43822A (en) 1987-12-28
CZ279028B6 (en) 1994-11-16
ZA871637B (en) 1987-10-28
SK736787A3 (en) 1998-06-03
LV5769B4 (lv) 1997-04-20
NO170277B (no) 1992-06-22
FI91857B (fi) 1994-05-13
PL264460A1 (en) 1988-07-21
SU1549478A3 (ru) 1990-03-07
IE61101B1 (en) 1994-10-05
EP0236940A2 (fr) 1987-09-16
NO870937L (no) 1987-09-08
NO1998010I1 (no) 1998-03-04
DK117687A (da) 1987-09-08
DE3787480T2 (de) 1994-02-24
KR910000482B1 (ko) 1991-01-25
JPH0755930B2 (ja) 1995-06-14
IE870575L (en) 1987-09-07
MA20888A1 (fr) 1987-10-01
MY102428A (en) 1992-06-30
FI870903A0 (fi) 1987-03-02
IL81746A (en) 1992-02-16
NL970011I2 (nl) 1997-09-01
ATE94873T1 (de) 1993-10-15
NO170277C (no) 1992-09-30
PL151490B1 (en) 1990-09-28
PH24159A (en) 1990-03-22
CZ279027B6 (en) 1994-11-16
CS8707368A2 (en) 1991-02-12
LU90128I2 (fr) 1997-10-06
DD264432A5 (de) 1989-02-01
AU604011B2 (en) 1990-12-06
NO870937D0 (no) 1987-03-06
SU1470184A3 (ru) 1989-03-30
CS8701512A2 (en) 1991-02-12
SK151287A3 (en) 1998-06-03
NL970011I1 (nl) 1997-05-01
US4749713A (en) 1988-06-07
DK172190B1 (da) 1997-12-22
IL81746A0 (en) 1987-10-20
KR870008851A (ko) 1987-10-21
EP0236940B1 (fr) 1993-09-22
CA1316928C (fr) 1993-04-27
PT84410A (en) 1987-04-01
BG45700A3 (en) 1989-07-14
SK279103B6 (sk) 1998-06-03
ES2059317T3 (es) 1994-11-16
HK50296A (en) 1996-03-29
FI870903A (fi) 1987-09-08
SU1577695A3 (ru) 1990-07-07
RO101532B1 (en) 1992-11-03
CZ279026B6 (en) 1994-11-16
TNSN87033A1 (fr) 1990-01-01
JPS62212369A (ja) 1987-09-18
LV5769A4 (lv) 1996-12-20
EP0236940A3 (en) 1989-10-18
DE3787480D1 (de) 1993-10-28
SK736887A3 (en) 1998-06-03
PT84410B (pt) 1989-10-04
BG61204B2 (bg) 1997-02-28
BG45701A3 (en) 1989-07-14
SK279101B6 (sk) 1998-06-03
FI91857C (fi) 1994-08-25
MX5496A (es) 1993-12-01
DE19775016I2 (de) 2002-02-21
SK279102B6 (sk) 1998-06-03
EP0236940B3 (fr) 2011-03-23
MTP998B (en) 1987-08-21
DZ1055A1 (fr) 2004-09-13
DK117687D0 (da) 1987-03-06
PL152025B1 (en) 1990-10-31
AU6976887A (en) 1987-09-10
BG46598A3 (en) 1990-01-15

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