MA32136B1 - Procedes de diagnostic et de traitement de maladies mediees par parp - Google Patents
Procedes de diagnostic et de traitement de maladies mediees par parpInfo
- Publication number
- MA32136B1 MA32136B1 MA33141A MA33141A MA32136B1 MA 32136 B1 MA32136 B1 MA 32136B1 MA 33141 A MA33141 A MA 33141A MA 33141 A MA33141 A MA 33141A MA 32136 B1 MA32136 B1 MA 32136B1
- Authority
- MA
- Morocco
- Prior art keywords
- disease
- differentially expressed
- expressed genes
- modulators
- parp
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B99/00—Subject matter not provided for in other groups of this subclass
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
Abstract
La présente invention concerne des procédés d'identification d'une maladie pouvant être traitée avec des modulateurs de gènes exprimés de manière différentielle dans une maladie, comprenant au moins les modulateurs de parp, par identification du niveau d'expression de gènes exprimés de manière différentielle, comprenant au moins parp, dans une pluralité d'échantillons provenant d'une population, impliquant une prise de décision concernant l'identification de la maladie pouvant être traitée par les modulateurs des gènes exprimés de manière différentielle, la décision étant prise en se basant sur le niveau d'expression des gènes exprimés de manière différentielle. Le procédé peut en outre comprendre le traitement de la maladie dans une population de sujets sans modulateurs des gènes exprimés de manière différentielle identifiés. Le procédé concerne l'identification de l'expression régulée à la hausse de gènes exprimés de manière différentielle identifiés dans une maladie et la prise d'une décision concernant le traitement de la maladie. Le niveau d'expression des gènes exprimés de manière différentielle dans une maladie peut également aider à déterminer l'efficacité du traitement avec les modulateurs des gènes exprimés de manière différentielle.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2607708P | 2008-02-04 | 2008-02-04 | |
PCT/US2009/033117 WO2009100159A2 (fr) | 2008-02-04 | 2009-02-04 | Procédés de diagnostic et de traitement de maladies médiées par parp |
Publications (1)
Publication Number | Publication Date |
---|---|
MA32136B1 true MA32136B1 (fr) | 2011-03-01 |
Family
ID=40952673
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA33141A MA32136B1 (fr) | 2008-02-04 | 2010-09-02 | Procedes de diagnostic et de traitement de maladies mediees par parp |
Country Status (13)
Country | Link |
---|---|
US (1) | US20090275608A1 (fr) |
EP (1) | EP2250282A4 (fr) |
JP (1) | JP2011521618A (fr) |
KR (1) | KR20100112192A (fr) |
CN (1) | CN101999002A (fr) |
AU (1) | AU2009212401A1 (fr) |
CA (1) | CA2713156A1 (fr) |
CO (1) | CO6331372A2 (fr) |
IL (1) | IL207360A0 (fr) |
MA (1) | MA32136B1 (fr) |
MX (1) | MX2010008572A (fr) |
RU (1) | RU2010136966A (fr) |
WO (1) | WO2009100159A2 (fr) |
Families Citing this family (89)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2447889C2 (ru) | 2005-07-18 | 2012-04-20 | Бипар Сайенсиз, Инк. | Способ лечения рака (варианты) |
US20100160442A1 (en) * | 2006-07-18 | 2010-06-24 | Ossovskaya Valeria S | Formulations for cancer treatment |
WO2008030892A2 (fr) * | 2006-09-05 | 2008-03-13 | Bipar Sciences, Inc. | Concept de médicament pour inhibiteurs de tubuline, compositions et procédés de traitement |
WO2008030883A2 (fr) | 2006-09-05 | 2008-03-13 | Bipar Sciences, Inc. | Traitement du cancer |
AU2007292306A1 (en) | 2006-09-05 | 2008-03-13 | Bipar Sciences, Inc. | Inhibition of fatty acid synthesis by PARP inhibitors and methods of treatment thereof |
US20120059228A1 (en) * | 2009-03-16 | 2012-03-08 | The Research Foundation Of State University Of New York | Methods for detecting endometriosis |
US9771618B2 (en) * | 2009-08-19 | 2017-09-26 | Bioarray Genetics, Inc. | Methods for treating breast cancer |
TWI449911B (zh) * | 2010-01-29 | 2014-08-21 | Nat Defense Medical Ct | 免疫球蛋白a型腎小球腎炎之分子標記及其應用 |
WO2011133918A1 (fr) * | 2010-04-23 | 2011-10-27 | Isis Pharmaceuticals, Inc. | Modulation de l'expression de la synthase gm3 (gm3s) |
US20120094859A1 (en) * | 2010-10-19 | 2012-04-19 | Eva Redei | Methods for detection of depressive disorders |
EP2671076A4 (fr) * | 2011-02-04 | 2016-11-16 | Bioarray Genetics Inc | Procédés d'utilisation de signatures d'expression génique pour sélectionner un procédé de traitement, prédire un pronostic, la survie, et/ou prédire une réponse à un traitement |
RU2013153096A (ru) * | 2011-04-29 | 2015-06-10 | Орхус Университет | Способ определения клинически значимой гипоксии при раке |
KR101439856B1 (ko) * | 2011-06-02 | 2014-09-17 | 한국생명공학연구원 | 항-atic 자가면역항체를 포함하는 간암 진단 마커 및 이의 항원을 포함하는 간암 진단용 조성물 |
CN104830972B (zh) * | 2011-09-16 | 2019-03-15 | 上海长海医院 | 前列腺癌的生物学标志物、治疗靶点及其用途 |
GB201202319D0 (en) * | 2012-02-10 | 2012-03-28 | Orbsen Therapeutics Ltd | Stromal stem cells |
WO2013134774A1 (fr) * | 2012-03-09 | 2013-09-12 | Cornell University | Modulation de la croissance du cancer du sein par modulation de l'activité de la xbp1 |
US9809858B2 (en) * | 2012-04-05 | 2017-11-07 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | O-glycan pathway ovarian cancer signature |
JP6263117B2 (ja) * | 2012-05-11 | 2018-01-17 | 公益財団法人微生物化学研究会 | 抗cxadr抗体 |
KR101495275B1 (ko) * | 2012-06-07 | 2015-02-24 | 한양대학교 산학협력단 | 폐암 진단 및 치료를 위한 표적 단백질 |
US9903870B2 (en) | 2012-10-04 | 2018-02-27 | The Wistar Institute Of Anatomy And Biology | Methods and compositions for the diagnosis of ovarian cancer |
WO2014061456A1 (fr) * | 2012-10-15 | 2014-04-24 | 国立大学法人名古屋大学 | Ensemble de marqueurs du syndrome du dysfonctionnement de l'intégration et son utilisation |
WO2014067038A1 (fr) * | 2012-10-29 | 2014-05-08 | 广州百赫医疗信息科技有限公司 | Point repère, préparation et méthode de traitement de carence en adsl chez l'être humain |
US20140148357A1 (en) * | 2012-11-29 | 2014-05-29 | Vanderbilt University | Characterizing Gastro-Intestinal Disease |
PL2984184T3 (pl) * | 2013-04-09 | 2021-06-14 | The Board Of Trustees Of The University Of Illinois | Stosowanie DNQ lub DNQ-87 w połączeniu z inhibitorem PARP1 do leczenia nowotworu |
US20160291024A1 (en) * | 2013-09-17 | 2016-10-06 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarkers for Ovarian Cancer |
KR101664291B1 (ko) * | 2014-04-25 | 2016-10-13 | 대한민국 | Hⅰv-1 tat의 전사 활성을 조절하는 신규 공활성인자 nucks1 |
WO2016037188A1 (fr) * | 2014-09-05 | 2016-03-10 | Duke University | Procédés et agents thérapeutiques relatifs à des biomarqueurs d'arnm pour le pronostic clinique du cancer |
WO2016113646A1 (fr) * | 2015-01-15 | 2016-07-21 | Koninklijke Philips N.V. | Tomodensitométrie ifr |
US11156599B2 (en) * | 2015-03-19 | 2021-10-26 | The Johns Hopkins University | Assay for telomere length regulators |
CN105067822B (zh) * | 2015-08-12 | 2017-05-24 | 中山大学附属肿瘤医院 | 用于食管癌诊断的标志物 |
CN105200137B (zh) * | 2015-09-28 | 2018-11-30 | 北京泱深生物信息技术有限公司 | Cers2基因及其表达产物作为骨质疏松症的诊治靶标 |
CN105256029B (zh) * | 2015-10-22 | 2018-07-24 | 山东省眼科研究所 | Chst6基因在制备检测斑块状角膜营养不良制品中的应用 |
CN105274225B (zh) * | 2015-10-22 | 2019-01-18 | 山东省眼科研究所 | 一种用于检测斑块状角膜营养不良病的snp位点 |
US20170216518A1 (en) * | 2016-02-01 | 2017-08-03 | Dexcom, Inc. | System and method for decision support using lifestyle factors |
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EP2329818A1 (fr) * | 2006-01-17 | 2011-06-08 | Abbott Laboratories | Polythérapie avec des inhibiteurs PARP |
US20080262062A1 (en) * | 2006-11-20 | 2008-10-23 | Bipar Sciences, Inc. | Method of treating diseases with parp inhibitors |
AU2007354301A1 (en) * | 2006-06-12 | 2008-12-04 | Bipar Sciences, Inc. | Method of treating diseases with PARP inhibitors |
WO2008030892A2 (fr) * | 2006-09-05 | 2008-03-13 | Bipar Sciences, Inc. | Concept de médicament pour inhibiteurs de tubuline, compositions et procédés de traitement |
US20080076778A1 (en) * | 2006-09-05 | 2008-03-27 | Bipar Sciences, Inc. | Methods for designing parp inhibitors and uses thereof |
WO2008030883A2 (fr) * | 2006-09-05 | 2008-03-13 | Bipar Sciences, Inc. | Traitement du cancer |
AU2007292306A1 (en) * | 2006-09-05 | 2008-03-13 | Bipar Sciences, Inc. | Inhibition of fatty acid synthesis by PARP inhibitors and methods of treatment thereof |
JP2010516626A (ja) * | 2007-01-16 | 2010-05-20 | バイパー サイエンシズ,インコーポレイティド | ガン治療剤 |
EP2217227B1 (fr) * | 2007-11-12 | 2013-08-21 | BiPar Sciences, Inc. | Traitement de cancer du sein avec 4-iodo-3-nitrobenzamide en combinaison avec des agents anti-tumoraux |
-
2009
- 2009-02-04 US US12/322,551 patent/US20090275608A1/en not_active Abandoned
- 2009-02-04 CA CA2713156A patent/CA2713156A1/fr not_active Abandoned
- 2009-02-04 MX MX2010008572A patent/MX2010008572A/es not_active Application Discontinuation
- 2009-02-04 AU AU2009212401A patent/AU2009212401A1/en not_active Abandoned
- 2009-02-04 EP EP09708089A patent/EP2250282A4/fr not_active Withdrawn
- 2009-02-04 WO PCT/US2009/033117 patent/WO2009100159A2/fr active Application Filing
- 2009-02-04 CN CN2009801124263A patent/CN101999002A/zh active Pending
- 2009-02-04 KR KR1020107019649A patent/KR20100112192A/ko not_active Application Discontinuation
- 2009-02-04 JP JP2010545281A patent/JP2011521618A/ja not_active Abandoned
- 2009-02-04 RU RU2010136966/10A patent/RU2010136966A/ru unknown
-
2010
- 2010-08-02 IL IL207360A patent/IL207360A0/en unknown
- 2010-08-27 CO CO10105931A patent/CO6331372A2/es not_active Application Discontinuation
- 2010-09-02 MA MA33141A patent/MA32136B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
US20090275608A1 (en) | 2009-11-05 |
RU2010136966A (ru) | 2012-03-20 |
CA2713156A1 (fr) | 2009-08-13 |
MX2010008572A (es) | 2010-11-30 |
EP2250282A2 (fr) | 2010-11-17 |
AU2009212401A1 (en) | 2009-08-13 |
EP2250282A4 (fr) | 2011-05-18 |
IL207360A0 (en) | 2010-12-30 |
CO6331372A2 (es) | 2011-10-20 |
CN101999002A (zh) | 2011-03-30 |
KR20100112192A (ko) | 2010-10-18 |
WO2009100159A3 (fr) | 2009-10-29 |
WO2009100159A2 (fr) | 2009-08-13 |
JP2011521618A (ja) | 2011-07-28 |
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