MA28011A1 - Derives de piperazine et leur utilisation en tant qu'agents therapeutiques - Google Patents
Derives de piperazine et leur utilisation en tant qu'agents therapeutiquesInfo
- Publication number
- MA28011A1 MA28011A1 MA28839A MA28839A MA28011A1 MA 28011 A1 MA28011 A1 MA 28011A1 MA 28839 A MA28839 A MA 28839A MA 28839 A MA28839 A MA 28839A MA 28011 A1 MA28011 A1 MA 28011A1
- Authority
- MA
- Morocco
- Prior art keywords
- therapeutic agents
- piperazine derivatives
- formula
- mammal
- methods
- Prior art date
Links
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical class C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Abstract
Des procédés de traitement d'une maladie ou d'une condition médiée par la SCD chez un mammifère, de préférence un humain, sont décrits, dans lesquels les procédés comprennent l'administration à un mammifère le nécessitant d'un composé de formule (I) : dans laquelle x, y, W, V, R2, R3, R4, R5, R6, R6a, R7, R7a, R8, R8a, R9, et R9a sont définis ci-dedans. Des compositions pharmaceutiques comprenant les composés de formule (I) sont également: décrites.
Applications Claiming Priority (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49109503P | 2003-07-30 | 2003-07-30 | |
US54689804P | 2004-02-23 | 2004-02-23 | |
US54678604P | 2004-02-23 | 2004-02-23 | |
US54681504P | 2004-02-23 | 2004-02-23 | |
US54682004P | 2004-02-23 | 2004-02-23 | |
US54693404P | 2004-02-23 | 2004-02-23 | |
US55340304P | 2004-03-16 | 2004-03-16 | |
US55349104P | 2004-03-16 | 2004-03-16 | |
US55341604P | 2004-03-16 | 2004-03-16 | |
US55344604P | 2004-03-16 | 2004-03-16 | |
US55340404P | 2004-03-16 | 2004-03-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA28011A1 true MA28011A1 (fr) | 2006-07-03 |
Family
ID=34120234
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA28839A MA28011A1 (fr) | 2003-07-30 | 2006-02-27 | Derives de piperazine et leur utilisation en tant qu'agents therapeutiques |
Country Status (23)
Country | Link |
---|---|
US (1) | US7335658B2 (fr) |
EP (3) | EP1648874B1 (fr) |
JP (1) | JP4808616B2 (fr) |
KR (1) | KR100934554B1 (fr) |
AR (1) | AR047557A1 (fr) |
AT (1) | ATE527242T1 (fr) |
AU (2) | AU2004261252C1 (fr) |
CA (1) | CA2533899C (fr) |
CY (1) | CY1112178T1 (fr) |
DK (1) | DK1648874T3 (fr) |
EC (1) | ECSP066313A (fr) |
ES (2) | ES2568769T3 (fr) |
HK (2) | HK1097256A1 (fr) |
HR (1) | HRP20110974T1 (fr) |
IL (1) | IL173395A (fr) |
MA (1) | MA28011A1 (fr) |
NO (1) | NO332822B1 (fr) |
NZ (1) | NZ545265A (fr) |
PL (1) | PL1648874T3 (fr) |
PT (1) | PT1648874E (fr) |
TN (1) | TNSN06034A1 (fr) |
TW (2) | TW201038270A (fr) |
WO (1) | WO2005011655A2 (fr) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040226056A1 (en) * | 1998-12-22 | 2004-11-11 | Myriad Genetics, Incorporated | Compositions and methods for treating neurological disorders and diseases |
US20050119251A1 (en) * | 2001-12-21 | 2005-06-02 | Jian-Min Fu | Nicotinamide derivatives and their use as therapeutic agents |
US7390813B1 (en) * | 2001-12-21 | 2008-06-24 | Xenon Pharmaceuticals Inc. | Pyridylpiperazines and aminonicotinamides and their use as therapeutic agents |
EP2316826A1 (fr) * | 2003-07-30 | 2011-05-04 | Xenon Pharmaceuticals Inc. | Dérivés de pyridazine et utilisation de ceux-ci en tant qu'agents thérapeutiques |
NZ545265A (en) | 2003-07-30 | 2009-11-27 | Xenon Pharmaceuticals Inc | Pyridazine derivatives and their use for treating diseases mediated by stearoyl-CoA desaturase (SCD) enzymes |
US7759348B2 (en) * | 2003-07-30 | 2010-07-20 | Xenon Pharmaceuticals Inc. | Pyridazine derivatives and their use as therapeutic agents |
SG145701A1 (en) * | 2003-07-30 | 2008-09-29 | Xenon Pharmaceuticals Inc | Piperazine derivatives and their use as therapeutic agents |
US7754711B2 (en) | 2003-07-30 | 2010-07-13 | Xenon Pharmaceuticals Inc. | Pyridazine derivatives and their use as therapeutic agents |
JP2007518816A (ja) * | 2004-01-23 | 2007-07-12 | アムジエン・インコーポレーテツド | バニロイド受容体リガンド及び炎症性及び神経因性疼痛の治療におけるこれらの使用 |
US7592343B2 (en) * | 2004-09-20 | 2009-09-22 | Xenon Pharmaceuticals Inc. | Pyridazine-piperazine compounds and their use as stearoyl-CoA desaturase inhibitors |
CN101084212A (zh) * | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为硬脂酰CoA去饱和酶介导剂的用途 |
MX2007003321A (es) * | 2004-09-20 | 2007-06-05 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como agentes terapeuticos. |
EP2316458A1 (fr) * | 2004-09-20 | 2011-05-04 | Xenon Pharmaceuticals Inc. | Derives de pyridazine destines a l'inhibition du desaturase-coa-stearoyl de l'humain |
EP2289510A1 (fr) | 2004-09-20 | 2011-03-02 | Xenon Pharmaceuticals Inc. | Dérivés hétérocycliques pour le traitement des maladies induites par des enzymes stearoyl-coa desaturase |
WO2006034440A2 (fr) * | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Derives heterocycliques et leur utilisation en tant qu'agents therapeutiques |
US20080167321A1 (en) * | 2004-09-20 | 2008-07-10 | Xenon Pharmaceuticals Inc. | Pyridine Derivatives For Inhibiting Human Stearoyl-Coa-Desaturase |
CN101084207A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途 |
BRPI0515477A (pt) * | 2004-09-20 | 2008-07-22 | Xenon Pharmaceuticals Inc | derivados heterocìclicos bicìclicos e o uso dos mesmos como inibidores de estaroil-coa-desaturase (scd) |
GT200600046A (es) * | 2005-02-09 | 2006-09-25 | Terapia de combinacion | |
WO2007044085A2 (fr) * | 2005-05-19 | 2007-04-19 | Xenon Pharmaceuticals Inc. | Composes heteroaryle et leurs utilisations en tant qu'agents therapeutiques |
WO2006125180A1 (fr) * | 2005-05-19 | 2006-11-23 | Xenon Pharmaceuticals Inc. | Derives de piperazine: utilisation comme agents therapeutiques |
WO2006125179A1 (fr) * | 2005-05-19 | 2006-11-23 | Xenon Pharmaceuticals Inc. | Composes tricycliques: utilisation comme agents therapeutiques |
CN101208089A (zh) * | 2005-06-03 | 2008-06-25 | 泽农医药公司 | 氨基噻唑衍生物作为人硬酯酰-CoA去饱和酶抑制剂 |
WO2007005763A2 (fr) * | 2005-07-01 | 2007-01-11 | Novartis Ag | Combinaison de composes organiques |
JO2769B1 (en) | 2005-10-26 | 2014-03-15 | جانسين فارماسوتيكا ان. في | Rapid decomposition of physiologically antagonistic agents of the 2-dopamine receptor |
AU2006326815A1 (en) * | 2005-12-20 | 2007-06-28 | Merck Frosst Canada Ltd. | Heteroaromatic compounds as inhibitors of stearoyl-coenzyme A delta-9 desaturase |
US7989461B2 (en) * | 2005-12-23 | 2011-08-02 | Amgen Inc. | Substituted quinazolinamine compounds for the treatment of cancer |
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CN101460476B (zh) | 2006-06-05 | 2013-12-04 | 诺瓦提斯公司 | 有机化合物 |
US8314138B2 (en) | 2006-08-24 | 2012-11-20 | Novartis Ag | Pyrazole derivative as SCD1 inhibitors for the treatment of diabetes |
US8246433B2 (en) * | 2006-08-25 | 2012-08-21 | Alma Mater Sports, Llc | Team based fantasy sport contest |
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EP2099755A2 (fr) * | 2006-11-20 | 2009-09-16 | Glenmark Pharmaceuticals S.A. | Dérivés d'acétylène comme inhibiteurs de la stéaroyl coa désaturase |
US8575167B2 (en) | 2007-02-06 | 2013-11-05 | Takeda Pharmaceutical Company Limited | Spiro compounds having stearoyl-CoA desaturase action |
JO2849B1 (en) * | 2007-02-13 | 2015-03-15 | جانسين فارماسوتيكا ان. في | Dopamine 2 receptor antagonists are rapidly hydrolyzed |
WO2008104524A1 (fr) * | 2007-02-28 | 2008-09-04 | Smithkline Beecham Corporation | Dérivés de thiadiazole, inhibiteurs de stéoryl-coa désaturase |
JP5431305B2 (ja) | 2007-04-23 | 2014-03-05 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 高速解離性ドパミン2受容体アンタゴニストとしての4−アルコキシピリダジン誘導体 |
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CA2833209C (fr) * | 2007-04-27 | 2016-06-28 | Purdue Pharma L.P. | Composes de piperidine et piperazine en tant qu'antagonistes de trpv1 |
EP2581081A3 (fr) | 2007-06-01 | 2013-07-31 | The Trustees Of Princeton University | Traitement d'infections virales par modulation de voies métaboliques de cellules hôtes |
WO2008157844A1 (fr) | 2007-06-21 | 2008-12-24 | Forest Laboratories Holdings Limited | Nouveaux dérivés de pipérazine en tant qu'inhibiteurs de stéaroyl-coa désaturase |
CN101821234B (zh) | 2007-08-08 | 2014-06-25 | 格里斯威医药有限责任公司 | 苯氧基吡咯烷衍生物及其应用和组合物 |
WO2009037542A2 (fr) | 2007-09-20 | 2009-03-26 | Glenmark Pharmaceuticals, S.A. | Composés spirocycliques en tant qu'inhibiteurs de stéaroyle coa désaturase |
BRPI0817211A2 (pt) | 2007-09-20 | 2017-05-16 | Irm Llc | composto composições como moduladores da atividade de gpr119 |
BRPI0820972A2 (pt) * | 2007-12-11 | 2018-08-14 | Hoffmann La Roche | compostos inibidores de estearoil-coa dessaturase 1, processo para a sua preparação, composição farmacêutica que compreende, uso dos mesmos e método para o tratamento e profilaxia de obesidade. |
DK2307374T3 (en) | 2008-07-31 | 2017-05-01 | Janssen Pharmaceutica Nv | PIPERAZIN-1-YLTRIFLUORMETHYL-SUBSTITUTED PYRIDINES AS QUICK DISSOCATING DOPAMIN-2 RECEPTOR ANTAGONISTS |
EP2398809B1 (fr) | 2009-02-17 | 2015-07-08 | Merck Canada Inc. | Nouveaux composés spiro utiles comme inhibiteurs de la stéaroyl-coenzyme a delta-9 désaturase |
EP2459568A4 (fr) | 2009-07-28 | 2013-02-27 | Merck Frosst Canada Ltd | Nouveaux composés spiro utiles en tant qu'inhibiteurs de la stéaroyl-coenzyme a delta-9 désaturase |
WO2011014520A2 (fr) | 2009-07-29 | 2011-02-03 | Irm Llc | Composés et compositions pouvant servir de modulateurs de l'activité du gpr119 |
US20130012709A1 (en) | 2009-09-10 | 2013-01-10 | Centre National De La Recherche Scientifique | NOVEL INHIBITORS OF STEAROYL-CoA-DESATURASE-1 AND THEIR USES |
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US8394858B2 (en) | 2009-12-03 | 2013-03-12 | Novartis Ag | Cyclohexane derivatives and uses thereof |
US8697739B2 (en) | 2010-07-29 | 2014-04-15 | Novartis Ag | Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof |
UA113288C2 (xx) | 2011-06-22 | 2017-01-10 | Trpv1 антагоністи, що містять дигідроксизамісник, і їх застосування | |
CA2850836A1 (fr) | 2011-10-15 | 2013-04-18 | Genentech, Inc. | Procedes d'utilisation d'antagonistes de scd1 |
US9260441B2 (en) | 2012-03-28 | 2016-02-16 | Intervet Inc. | Heteroaryl compounds with cyclic bridging unit |
RU2014149559A (ru) | 2012-05-22 | 2016-06-27 | Ийсум Рисёч Девелопмент Кампани Оф Зэ Хибру Юниверсити Оф Иерусалим Лтд. | Селективные ингибиторы недифференцированных клеток |
WO2014052619A1 (fr) | 2012-09-27 | 2014-04-03 | Irm Llc | Dérivés et compositions de pipéridine comme modulateurs de l'activité de gpr119 |
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WO2019084157A1 (fr) | 2017-10-24 | 2019-05-02 | Yumanity Therapeutics, Inc. | Composés et utilisations de ces composés |
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2004
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- 2004-07-29 AT AT04779562T patent/ATE527242T1/de active
- 2004-07-29 KR KR1020067002017A patent/KR100934554B1/ko not_active IP Right Cessation
- 2004-07-29 PT PT04779562T patent/PT1648874E/pt unknown
- 2004-07-29 AU AU2004261252A patent/AU2004261252C1/en not_active Ceased
- 2004-07-29 US US10/901,563 patent/US7335658B2/en not_active Expired - Fee Related
- 2004-07-29 CA CA2533899A patent/CA2533899C/fr active Active
- 2004-07-29 TW TW099123172A patent/TW201038270A/zh unknown
- 2004-07-29 ES ES10184939.6T patent/ES2568769T3/es active Active
- 2004-07-29 EP EP04779562A patent/EP1648874B1/fr active Active
- 2004-07-29 TW TW093122736A patent/TWI345974B/zh not_active IP Right Cessation
- 2004-07-29 JP JP2006522075A patent/JP4808616B2/ja not_active Expired - Fee Related
- 2004-07-29 ES ES04779562T patent/ES2375134T3/es active Active
- 2004-07-29 AR ARP040102690A patent/AR047557A1/es not_active Application Discontinuation
- 2004-07-29 EP EP16000190.5A patent/EP3042895A1/fr not_active Withdrawn
- 2004-07-29 PL PL04779562T patent/PL1648874T3/pl unknown
- 2004-07-29 EP EP10184939.6A patent/EP2316827B1/fr active Active
- 2004-07-29 DK DK04779562.0T patent/DK1648874T3/da active
- 2004-07-29 WO PCT/US2004/024548 patent/WO2005011655A2/fr active Application Filing
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- 2006-01-26 IL IL173395A patent/IL173395A/en not_active IP Right Cessation
- 2006-01-27 TN TNP2006000034A patent/TNSN06034A1/en unknown
- 2006-02-27 MA MA28839A patent/MA28011A1/fr unknown
- 2006-02-28 NO NO20060981A patent/NO332822B1/no not_active IP Right Cessation
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2007
- 2007-02-01 HK HK07101166.9A patent/HK1097256A1/xx not_active IP Right Cessation
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- 2009-05-05 AU AU2009201788A patent/AU2009201788B2/en not_active Ceased
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