LV10960B - Process for preparation of intermediate products - Google Patents

Process for preparation of intermediate products Download PDF

Info

Publication number
LV10960B
LV10960B LVP-93-818A LV930818A LV10960B LV 10960 B LV10960 B LV 10960B LV 930818 A LV930818 A LV 930818A LV 10960 B LV10960 B LV 10960B
Authority
LV
Latvia
Prior art keywords
sub
hjih
hydrogen
quot
mji
Prior art date
Application number
LVP-93-818A
Other languages
English (en)
Latvian (lv)
Other versions
LV10960A (lv
Inventor
Paul Hakan Andersson
Per Ture Andersson
Bengt Ingemar Axelsson
Bror Arne Thalen
Jan William Trofast
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Publication of LV10960A publication Critical patent/LV10960A/xx
Publication of LV10960B publication Critical patent/LV10960B/lv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Threshing Machine Elements (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
LVP-93-818A 1985-04-04 1993-06-30 Process for preparation of intermediate products LV10960B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8501693A SE8501693D0 (sv) 1985-04-04 1985-04-04 Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters

Publications (2)

Publication Number Publication Date
LV10960A LV10960A (lv) 1995-12-20
LV10960B true LV10960B (en) 1996-08-20

Family

ID=20359775

Family Applications (3)

Application Number Title Priority Date Filing Date
LVP-93-861A LV10281B (en) 1985-04-04 1993-06-30 Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
LVP-93-818A LV10960B (en) 1985-04-04 1993-06-30 Process for preparation of intermediate products
LVP-93-1006A LV10957B (en) 1985-04-04 1993-07-30 16 alpha, 17alpha-acetalsubstituted androstan-17betha-carboxyl acid esters, method of their preparation, intermediates, method of their producing, pharmaceutical compositions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LVP-93-861A LV10281B (en) 1985-04-04 1993-06-30 Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters

Family Applications After (1)

Application Number Title Priority Date Filing Date
LVP-93-1006A LV10957B (en) 1985-04-04 1993-07-30 16 alpha, 17alpha-acetalsubstituted androstan-17betha-carboxyl acid esters, method of their preparation, intermediates, method of their producing, pharmaceutical compositions

Country Status (31)

Country Link
US (1) US4950659A (da)
EP (2) EP0197018B1 (da)
JP (1) JPH0762028B2 (da)
KR (1) KR930009444B1 (da)
CN (1) CN1021444C (da)
AT (2) ATE107657T1 (da)
AU (1) AU590545B2 (da)
CA (1) CA1333597C (da)
CS (1) CS266581B2 (da)
DD (2) DD247681A5 (da)
DE (2) DE3687239T2 (da)
DK (3) DK165638C (da)
ES (2) ES8800264A1 (da)
FI (1) FI85378C (da)
GR (1) GR860902B (da)
HU (2) HU196830B (da)
IE (1) IE61474B1 (da)
IL (1) IL78143A0 (da)
JO (1) JO1479B1 (da)
LT (3) LT3913B (da)
LV (3) LV10281B (da)
MY (1) MY102056A (da)
NO (1) NO165298C (da)
NZ (1) NZ215586A (da)
PH (2) PH23547A (da)
PL (2) PL148272B1 (da)
PT (1) PT82340B (da)
RU (3) RU1795972C (da)
SE (1) SE8501693D0 (da)
UA (2) UA19288A (da)
ZA (1) ZA861884B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8501693D0 (sv) 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
HU203769B (en) * 1989-03-09 1991-09-30 Richter Gedeon Vegyeszet Process for producing new steroide derivatives and pharmaceutical compositions containing them
AU672669B2 (en) * 1992-12-24 1996-10-10 Rhone-Poulenc Rorer Limited New steroids
GB9423919D0 (en) * 1994-11-26 1995-01-11 Rhone Poulenc Rorer Ltd Chemical process
GB0110411D0 (en) * 2001-04-27 2001-06-20 Astrazeneca Ab Chemical process

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3828080A (en) * 1972-01-20 1974-08-06 Glaxo Lab Ltd Androstane-17beta-carboxylic acids and processes for the preparation thereof
SE378109B (da) * 1972-05-19 1975-08-18 Bofors Ab
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
GB1517278A (en) * 1974-08-30 1978-07-12 Glaxo Lab Ltd Alkyl and haloalkyl androsta-1,4,15-triene and-4,15-diene-17beta-carboxylates
CH628355A5 (de) * 1976-02-24 1982-02-26 Ciba Geigy Ag Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.
US4198336A (en) * 1978-04-05 1980-04-15 Syntex (U.S.A.) Inc. Chemical process for preparing androsta-4-ene 17α-carboxylic acids
SE449106B (sv) * 1980-07-10 1987-04-06 Otsuka Pharma Co Ltd Steroid med anti-inflammatorisk verkan samt komposition innehallande denna
ZA814440B (en) * 1980-07-10 1982-10-27 Otsuka Pharma Co Ltd Soft steroids having anti-inflammatory activity
ZA817929B (en) * 1980-12-22 1982-10-27 Upjohn Co 5alpha-and 5beta-androstane-17beta-carboxylates
SE8306370D0 (sv) * 1983-11-18 1983-11-18 Draco Ab Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
SE8501693D0 (sv) 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
JP2687768B2 (ja) * 1991-07-30 1997-12-08 トヨタ自動車株式会社 エンジンの制御装置

Also Published As

Publication number Publication date
DE3687239D1 (de) 1993-01-21
CN1021444C (zh) 1993-06-30
UA13319A (uk) 1997-02-28
RU2081879C1 (ru) 1997-06-20
JPS61236794A (ja) 1986-10-22
CS266581B2 (en) 1990-01-12
LV10957A (lv) 1995-12-20
LV10281B (en) 1995-04-20
KR930009444B1 (ko) 1993-10-04
DE3689936D1 (de) 1994-07-28
DK59392D0 (da) 1992-05-05
DK59392A (da) 1992-05-05
DK167574B1 (da) 1993-11-22
IE61474B1 (en) 1994-11-02
DK138386D0 (da) 1986-03-25
FI861275A0 (fi) 1986-03-25
CA1333597C (en) 1994-12-20
LTIP1677A (en) 1995-07-25
IL78143A0 (en) 1986-07-31
FI85378B (fi) 1991-12-31
RU1795972C (ru) 1993-02-15
DE3689936T2 (de) 1994-09-29
PL150052B1 (en) 1990-04-30
HUT40809A (en) 1987-02-27
DD247681A5 (de) 1987-07-15
SE8501693D0 (sv) 1985-04-04
EP0197018A1 (en) 1986-10-08
LTIP1678A (en) 1995-07-25
LT3812B (en) 1996-03-25
LV10957B (en) 1996-04-20
JPH0762028B2 (ja) 1995-07-05
PL148272B1 (en) 1989-09-30
UA19288A (uk) 1997-12-25
LV10960A (lv) 1995-12-20
MY102056A (en) 1992-03-31
DK138386A (da) 1986-10-05
NZ215586A (en) 1990-01-29
PT82340B (pt) 1988-10-14
AU5486886A (en) 1986-10-16
ES557314A0 (es) 1988-05-16
FI861275A (fi) 1986-10-05
GR860902B (en) 1986-07-29
EP0355859A1 (en) 1990-02-28
LV10281A (lv) 1994-10-20
AU590545B2 (en) 1989-11-09
NO165298B (no) 1990-10-15
FI85378C (fi) 1992-04-10
RU1779257C (ru) 1992-11-30
LTIP1676A (en) 1995-07-25
CS232886A2 (en) 1989-04-14
HU196830B (en) 1989-01-30
ES8800264A1 (es) 1987-10-16
NO861313L (no) 1986-10-06
ATE83241T1 (de) 1992-12-15
EP0355859B1 (en) 1994-06-22
DK59693A (da) 1993-05-21
DK165638C (da) 1993-06-01
PL265699A1 (en) 1988-03-03
DE3687239T2 (de) 1993-04-15
DK167150B1 (da) 1993-09-06
DK165638B (da) 1992-12-28
PT82340A (en) 1986-05-01
JO1479B1 (en) 1988-03-10
KR860008208A (ko) 1986-11-14
PH24369A (en) 1990-06-13
EP0197018B1 (en) 1992-12-09
LT3913B (en) 1996-04-25
NO165298C (no) 1991-01-23
ZA861884B (en) 1987-07-29
ATE107657T1 (de) 1994-07-15
DK59693D0 (da) 1993-05-21
US4950659A (en) 1990-08-21
ES8802392A1 (es) 1988-05-16
ES553675A0 (es) 1987-10-16
IE860879L (en) 1986-10-04
PH23547A (en) 1989-08-25
DD261364A5 (de) 1988-10-26
HU199872B (en) 1990-03-28
CN86102193A (zh) 1987-09-02
LT3811B (en) 1996-03-25

Similar Documents

Publication Publication Date Title
RU2016110718A (ru) Композиции, содержащие фторзамещенные олефины
AU2017281903B2 (en) Degradation of bromodomain-containing protein 9 (BRD9) by conjugation of BRD9 inhibitors with E3 ligase ligand and methods of use
NZ744349A (en) Pyrazolo[1,5-a]pyrazin-4-yl derivatives as jak-inhibitors
MX2018002916A (es) Metodos, composiciones y usos de nuevos inhibidores de fyn quinasa.
LV10960B (en) Process for preparation of intermediate products
SI3880676T1 (sl) Derivati 2,3-dihidro-1h-pirolo(3,4-c)piridin-1-ona kot zaviralci hpk1 za zdravljenje raka
WO2010143168A3 (en) Compounds useful for treating cancer
AR023836A1 (es) Metodo y composicion para inhibir la corrosion en los sistemas acuosos
FR2918061A1 (fr) Derives de 6-cycloamino-3-(pyridin-4-yl)imidazo[1,2-b]- pyridazine,leur preparation et leur application en therapeutique.
PE20191236A1 (es) Compuestos de pirazolopirimidina y metodos de uso de los mismos
MX2021002051A (es) Imidazo[1,2-b]piridaziinas como inhibidores de trk.
EP4072548A4 (en) COMPOSITIONS AND METHODS FOR SUBSTITUTED 7-(PIPERAZINE-1-YL)PYRAZOLO[ 1,5-A]PYRIMIDINE ANALOGUES AS INHIBITORS BY KRAS
WO2020061252A1 (en) Inhibiting ubiquitin specific peptidase 9x
FR2934994A1 (fr) Derives de 2-alkyl-6cycloamino-3-(pyridin-4-yl)imidaz°1,2-b! pyridazine, leur preparation et leur application en therapeutique
MX2023009379A (es) Derivados de tetrahidroazepina biciclicos para el tratamiento del cancer.
PH12018501489A1 (en) Compounds and compositions for the treatment of cryptosporidiosis
MX367633B (es) Nueva sintesis quiral de n-acil-(3-sustituidas)-(8-sustituidas)-5, 6-dihidro-[1,2,4]triazolo[4,3-a]pirazinas.
ZA202106014B (en) Solid forms of condensed pyrazines as syk inhibitors
Koch et al. Electrochemical reduction of di-Schiff bases. Synthesis of piperazines, indoloindoles, diazepines, and diazocines
PH12016502344A1 (en) Pyridine derivative
ES8505684A1 (es) Procedimiento para preparar (1, 2, 4) triazol (1, 5-c)pirimidin-2-aminas 5-sustituidas
GB772109A (en) Unsaturated polyfluorinated organic compounds
MX2021015772A (es) Compuesto de carbonato novedoso que tiene esqueleto de pirrolopirimidina o sal farmaceuticamente aceptable del mismo.
US2889372A (en) Certificate of correction
EP3172216B1 (en) 2,3'-anhydro-2'-déoxy-5-fluorouridine derivatives with cytotoxic activity, a manufacturing process and use thereof