LU92488I2 - Dimethyl fumarate - Google Patents

Dimethyl fumarate Download PDF

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Publication number
LU92488I2
LU92488I2 LU92488C LU92488C LU92488I2 LU 92488 I2 LU92488 I2 LU 92488I2 LU 92488 C LU92488 C LU 92488C LU 92488 C LU92488 C LU 92488C LU 92488 I2 LU92488 I2 LU 92488I2
Authority
LU
Luxembourg
Prior art keywords
dimethyl fumarate
dialkyl fumarates
transplantation medicine
cyclosporines
pellets
Prior art date
Application number
LU92488C
Other languages
English (en)
French (fr)
Original Assignee
Biogen Idec Internat Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7888396&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU92488(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Idec Internat Gmbh filed Critical Biogen Idec Internat Gmbh
Publication of LU92488I2 publication Critical patent/LU92488I2/xx

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
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    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
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    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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    • A61K9/2022—Organic macromolecular compounds
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    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)
LU92488C 1998-11-19 2014-06-27 Dimethyl fumarate LU92488I2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853487A DE19853487A1 (de) 1998-11-19 1998-11-19 Verwendung von Dialkylfumaraten

Publications (1)

Publication Number Publication Date
LU92488I2 true LU92488I2 (fr) 2015-11-02

Family

ID=7888396

Family Applications (1)

Application Number Title Priority Date Filing Date
LU92488C LU92488I2 (fr) 1998-11-19 2014-06-27 Dimethyl fumarate

Country Status (34)

Country Link
US (9) US6509376B1 (es)
EP (1) EP1131065B1 (es)
JP (7) JP2002530324A (es)
CN (2) CN1615839A (es)
AT (1) ATE242633T1 (es)
BE (1) BE2014C040I2 (es)
BG (1) BG64837B1 (es)
BR (1) BR9914606A (es)
CA (1) CA2346438C (es)
CY (1) CY2014027I1 (es)
CZ (1) CZ299409B6 (es)
DE (2) DE19853487A1 (es)
DK (1) DK1131065T3 (es)
EE (1) EE04389B1 (es)
ES (1) ES2195664T3 (es)
FR (1) FR14C0051I2 (es)
HK (1) HK1042242B (es)
HU (2) HU226689B1 (es)
IL (2) IL142728A0 (es)
LT (1) LTC1131065I2 (es)
LU (1) LU92488I2 (es)
ME (1) ME00731B (es)
MX (1) MXPA01005007A (es)
NO (3) NO333257B1 (es)
NZ (1) NZ510247A (es)
PL (2) PL205948B1 (es)
PT (1) PT1131065E (es)
RS (1) RS49995B (es)
RU (1) RU2215524C2 (es)
SI (1) SI1131065T1 (es)
SK (1) SK285601B6 (es)
TR (1) TR200101204T2 (es)
WO (1) WO2000030622A2 (es)
ZA (1) ZA200202335B (es)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19853487A1 (de) * 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
DE10000577A1 (de) * 2000-01-10 2001-07-26 Fumapharm Ag Muri Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten
US6912052B2 (en) * 2000-11-17 2005-06-28 Cymer, Inc. Gas discharge MOPA laser spectral analysis module
CZ304198B6 (cs) * 2001-01-12 2013-12-27 Fumapharm Ag Amidy kyseliny fumarové
DE10101307A1 (de) * 2001-01-12 2002-08-01 Fumapharm Ag Muri Fumarsäurederivate als NF-kappaB-Inhibitor
US20050259709A1 (en) * 2002-05-07 2005-11-24 Cymer, Inc. Systems and methods for implementing an interaction between a laser shaped as a line beam and a film deposited on a substrate
DE10217314A1 (de) * 2002-04-18 2003-11-13 Fumapharm Ag Muri Carbocyclische und Oxacarboncyclische Fumarsäure-Oligomere
WO2004112773A1 (fr) * 2003-04-24 2004-12-29 Shin-Jen Shiao Compositions pharmaceutiques utilisees pour le traitement de maladie immune et amelioration
US7277188B2 (en) * 2003-04-29 2007-10-02 Cymer, Inc. Systems and methods for implementing an interaction between a laser shaped as a line beam and a film deposited on a substrate
PL1663197T3 (pl) * 2003-09-09 2008-09-30 Biogen Idec Int Gmbh Zastosowanie pochodnych kwasu fumarowego do leczenia niewydolności serca oraz astmy
DE10360869A1 (de) * 2003-09-09 2005-04-07 Fumapharm Ag Verwendung von Fumarsäurederivaten zur Therapie der Herzinsuffizienz, der Hyperkeratose und von Asthma
DE10342423A1 (de) * 2003-09-13 2005-04-14 Heidland, August, Prof. Dr.med. Dr.h.c. Verwendung von Fumarsäurederivaten zur Prophylaxe und zur Behandlung von Genomschäden
US6873418B1 (en) 2003-09-30 2005-03-29 Cymer, Inc. Optical mountings for gas discharge MOPA laser spectral analysis module
US6894785B2 (en) * 2003-09-30 2005-05-17 Cymer, Inc. Gas discharge MOPA laser spectral analysis module
CA2478458A1 (en) * 2004-08-20 2006-02-20 Michael Panzara Treatment of pediatric multiple sclerosis
DK1799196T3 (en) 2004-10-08 2016-08-15 Forward Pharma As Controlled release pharmaceutical compositions comprising a fumaric acid ester
US20080004344A1 (en) * 2004-11-10 2008-01-03 Aditech Pharma Ab Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use
US7653095B2 (en) * 2005-06-30 2010-01-26 Cymer, Inc. Active bandwidth control for a laser
EP1915334A2 (en) * 2005-07-07 2008-04-30 Aditech Pharma AB Novel salts of fumaric acid monoalkylesters and their pharmaceutical use
US20100144651A1 (en) * 2005-07-07 2010-06-10 Aditech Pharma Ab Novel glucopyranose esters and glucofuranose esters of alkyl- fumarates and their pharmaceutical use
WO2007042035A2 (en) * 2005-10-07 2007-04-19 Aditech Pharma Ab Combination therapy with fumaric acid esters for the treatment of autoimmune and/or inflammatory disorders
US20080299196A1 (en) * 2005-10-07 2008-12-04 Aditech Pharma Ab Controlled Release Pharmaceutical Compositions Comprising a Fumaric Acid Ester
US7679029B2 (en) * 2005-10-28 2010-03-16 Cymer, Inc. Systems and methods to shape laser light as a line beam for interaction with a substrate having surface variations
US7317179B2 (en) * 2005-10-28 2008-01-08 Cymer, Inc. Systems and methods to shape laser light as a homogeneous line beam for interaction with a film deposited on a substrate
LT2653873T (lt) * 2007-02-08 2022-10-10 Biogen Ma Inc. Kompozicijos ir naudojimas, skirti išsėtinei sklerozei gydyti
ES2599227T3 (es) * 2007-02-08 2017-01-31 Biogen Ma Inc. Neuroprotección en enfermedades desmielinizantes
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US7803840B2 (en) 2010-09-28
BG105396A (en) 2001-12-29
RS49995B (sr) 2008-09-29
EP1131065A2 (de) 2001-09-12
US20070248663A1 (en) 2007-10-25
BG64837B1 (bg) 2006-06-30
AU1157200A (en) 2000-06-13
CA2346438A1 (en) 2000-06-02
HK1042242B (zh) 2005-08-19
ES2195664T3 (es) 2003-12-01
DE59905954D1 (de) 2003-07-17
BR9914606A (pt) 2001-07-03
JP2002530324A (ja) 2002-09-17
IL142728A (en) 2006-12-10
JP2005097323A (ja) 2005-04-14
HUP0103182A2 (hu) 2002-01-28
EE04389B1 (et) 2004-12-15
CY2014027I1 (el) 2015-12-09
US20090182047A1 (en) 2009-07-16
US20030018072A1 (en) 2003-01-23
BE2014C040I2 (es) 2019-03-13
SI1131065T1 (en) 2003-10-31
US20140066505A1 (en) 2014-03-06
PL205948B1 (pl) 2010-06-30
NO20121479L (no) 2001-05-18
RU2215524C2 (ru) 2003-11-10
ATE242633T1 (de) 2003-06-15
US8524773B2 (en) 2013-09-03
FR14C0051I2 (fr) 2019-01-18
ZA200202335B (en) 2003-08-27
CA2346438C (en) 2006-10-03
US7320999B2 (en) 2008-01-22
CZ299409B6 (cs) 2008-07-16
NO2014016I2 (no) 2018-08-20
MXPA01005007A (es) 2002-04-24
PT1131065E (pt) 2003-10-31
NO20011242L (no) 2001-05-18
US7915310B2 (en) 2011-03-29
EP1131065B1 (de) 2003-06-11
SK285601B6 (sk) 2007-04-05
DK1131065T3 (da) 2003-08-25
US20110293711A1 (en) 2011-12-01

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