KR850005858A - 메틸하이드록시프로게스테론 아세테이트를 수팽윤 가능한 수불용성 폴리머에 첨가하는 방법 - Google Patents

메틸하이드록시프로게스테론 아세테이트를 수팽윤 가능한 수불용성 폴리머에 첨가하는 방법 Download PDF

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Publication number
KR850005858A
KR850005858A KR1019850000786A KR850000786A KR850005858A KR 850005858 A KR850005858 A KR 850005858A KR 1019850000786 A KR1019850000786 A KR 1019850000786A KR 850000786 A KR850000786 A KR 850000786A KR 850005858 A KR850005858 A KR 850005858A
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South Korea
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polymer
map
water insoluble
water
insoluble polymer
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KR1019850000786A
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English (en)
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KR930009897B1 (ko
Inventor
카를리 파비오
Original Assignee
죠지오 올란도
파미탈리아 카를로 에르바 에스. 피. 에이.
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Publication of KR850005858A publication Critical patent/KR850005858A/ko
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone

Abstract

내용 없음

Description

메틸하이드록시 프로게스테론 아세테이트를 수팽윤 가능한 수불용성 폴리머에 첨가하는 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. 수팽윤 가능한 수불용성 폴리머 및 메틸하이드록시-프로게스테론 아세테이트(MAP)의 혼합물을 제조한 후 분쇄하고/하거나, 후속 가열단계에 안정한 상기 폴리머와 MAP의 혼합물을 제조하여 MAP의 융점까지 가열시키고/시키거나, 상기 폴리머를 MAP 용약으로 팽윤시키고 수득된 팽윤 폴리머/MAP시스템을 건조시킴을 특징으로 하여, 수팽윤가능한 수불용성 폴리머에 MAP를 첨가하는 방법.
  2. 제1항에 있어서, MAP:팽윤가능한 폴리머의 중량비가 1:0.1 내지 1:100W/W인 방법.
  3. 제1 또는 2항에 있어서, 물중에서 팽윤될 수 있는 수불용성 폴리머 2개이상을 사용하는 방법.
  4. 제1 내지 3항중 어느 하나에 있어서, 팽윤가능한 수불용성 폴리머가 교차결합된 폴리비닐피롤리돈인 방법
  5. 제1 내지 4항중 어느 하나에 있어서, 팽윤가능한 수불용성 폴리머가 교차결합된 나트륨 카복시메틸셀룰로즈인 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019850000786A 1984-02-08 1985-02-08 메틸하이드록시프로게스테론 아세테이트를 수팽윤성 수불용성 폴리머에 첨가하는 방법 KR930009897B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8403360 1984-02-08
GB848403360A GB8403360D0 (en) 1984-02-08 1984-02-08 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
KR850005858A true KR850005858A (ko) 1985-09-26
KR930009897B1 KR930009897B1 (ko) 1993-10-13

Family

ID=10556300

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850000786A KR930009897B1 (ko) 1984-02-08 1985-02-08 메틸하이드록시프로게스테론 아세테이트를 수팽윤성 수불용성 폴리머에 첨가하는 방법

Country Status (32)

Country Link
US (1) US4632828A (ko)
JP (1) JPS60181017A (ko)
KR (1) KR930009897B1 (ko)
AT (1) AT388869B (ko)
AU (1) AU577351B2 (ko)
BE (1) BE901664A (ko)
BG (1) BG60524B2 (ko)
CA (1) CA1240928A (ko)
CH (1) CH664693A5 (ko)
CZ (1) CZ277728B6 (ko)
DE (1) DE3503679A1 (ko)
DK (1) DK164149C (ko)
ES (3) ES8607984A1 (ko)
FI (1) FI84230C (ko)
FR (1) FR2559065B1 (ko)
GB (2) GB8403360D0 (ko)
GR (1) GR850312B (ko)
HK (1) HK94290A (ko)
HU (1) HU194050B (ko)
IE (1) IE58230B1 (ko)
IL (1) IL74241A (ko)
IT (1) IT1209615B (ko)
NL (1) NL192780C (ko)
NO (1) NO170568C (ko)
NZ (1) NZ211058A (ko)
PT (1) PT79933B (ko)
SE (2) SE462547B (ko)
SG (1) SG80390G (ko)
SK (1) SK278084B6 (ko)
SU (1) SU1605926A3 (ko)
UA (1) UA6028A1 (ko)
ZA (1) ZA85943B (ko)

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US5019562A (en) * 1988-01-19 1991-05-28 The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation Growth inhibiting agent and the use thereof
GB8806367D0 (en) * 1988-03-17 1988-04-13 Erba Carlo Spa Siloxane matrices with internal non-uniform drug distribution
IE60458B1 (en) * 1989-10-26 1994-07-13 Elan Corp Plc Enhanced bioavailability adsorbates
HU222501B1 (hu) * 1991-06-28 2003-07-28 Endorecherche Inc. MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
US5547948A (en) * 1995-01-17 1996-08-20 American Home Products Corporation Controlled release of steroids from sugar coatings
US5759577A (en) * 1995-01-17 1998-06-02 American Home Products Corporation Controlled release of steroids from sugar coatings
UA65607C2 (uk) 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
DE19847252B4 (de) * 1998-10-02 2004-02-12 Jenapharm Gmbh & Co. Kg Bukkal applizierbare bioadhäsive Systeme mit zeitlich gesteuerter Wirkstofffreisetzung enthaltend Testosteronester und fakultativ zusätzlich Testosteron
AU2669700A (en) * 1999-02-24 2000-09-14 Akzo Nobel N.V. Pharmaceutical compositions containing a crystalline form of the progestagen-(17alpha)-17-hydroxy-11-methylene-19-nor-pregna- 4,15-dien-20-yn-3-one (org 30659) and lactose
US20020132839A1 (en) * 2000-06-22 2002-09-19 Ganter Sabina Maria Tablet formulations comprising valsartan
AUPS244002A0 (en) * 2002-05-20 2002-06-13 John Kohnke Products Pty Ltd Agent delivery system
DE10247037A1 (de) * 2002-10-09 2004-04-22 Abbott Gmbh & Co. Kg Herstellung von festen Dosierungsformen unter Verwendung eines vernetzten nichtthermoplastischen Trägers
JP2005094910A (ja) * 2003-09-17 2005-04-07 Aruze Corp モータ停止制御装置

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Also Published As

Publication number Publication date
SE8500553L (sv) 1985-08-09
GB8503033D0 (en) 1985-03-06
NL192780B (nl) 1997-10-01
KR930009897B1 (ko) 1993-10-13
HK94290A (en) 1990-11-23
DE3503679C2 (ko) 1992-05-07
ES8703278A1 (es) 1987-02-16
IE58230B1 (en) 1993-08-11
BE901664A (fr) 1985-08-06
DK164149C (da) 1992-10-12
ATA31685A (de) 1989-02-15
CH664693A5 (de) 1988-03-31
SK278084B6 (en) 1995-12-06
GR850312B (ko) 1985-06-05
GB2153677A (en) 1985-08-29
DK164149B (da) 1992-05-18
JPH0415769B2 (ko) 1992-03-19
BG60524B2 (bg) 1995-07-28
FR2559065B1 (fr) 1988-09-09
IT1209615B (it) 1989-08-30
FR2559065A1 (fr) 1985-08-09
FI850455L (fi) 1985-08-09
NL8500323A (nl) 1985-09-02
IE850261L (en) 1985-08-08
ES550614A0 (es) 1987-02-16
NL192780C (nl) 1998-02-03
CA1240928A (en) 1988-08-23
FI84230B (fi) 1991-07-31
NO170568B (no) 1992-07-27
NZ211058A (en) 1988-09-29
AU3848885A (en) 1985-08-15
AU577351B2 (en) 1988-09-22
JPS60181017A (ja) 1985-09-14
SU1605926A3 (ru) 1990-11-07
ZA85943B (en) 1985-10-30
SE462547B (sv) 1990-07-16
ES8703277A1 (es) 1987-02-16
UA6028A1 (uk) 1994-12-29
CZ277728B6 (en) 1993-04-14
HU194050B (en) 1988-01-28
ES8607984A1 (es) 1986-06-01
SE8500553D0 (sv) 1985-02-06
NO170568C (no) 1992-11-04
NO850477L (no) 1985-08-09
SG80390G (en) 1990-11-23
ES539874A0 (es) 1986-06-01
ES550613A0 (es) 1987-02-16
DK57085A (da) 1985-08-09
GB8403360D0 (en) 1984-03-14
HUT37890A (en) 1986-03-28
US4632828A (en) 1986-12-30
IL74241A (en) 1988-12-30
IT8519385A0 (it) 1985-02-05
PT79933B (en) 1987-02-02
PT79933A (en) 1985-03-01
FI850455A0 (fi) 1985-02-04
FI84230C (fi) 1991-11-11
IL74241A0 (en) 1985-05-31
CS78485A3 (en) 1992-11-18
DK57085D0 (da) 1985-02-07
DE3503679A1 (de) 1985-08-08
GB2153677B (en) 1988-04-13
AT388869B (de) 1989-09-11

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