KR20180053419A - 무조(無調)의 동소체 1 (atoh1)에 대한 자연 안티센스 전사체의 저해에 의한 atoh1 관련된 질환의 치료 - Google Patents

무조(無調)의 동소체 1 (atoh1)에 대한 자연 안티센스 전사체의 저해에 의한 atoh1 관련된 질환의 치료 Download PDF

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KR20180053419A
KR20180053419A KR1020187012859A KR20187012859A KR20180053419A KR 20180053419 A KR20180053419 A KR 20180053419A KR 1020187012859 A KR1020187012859 A KR 1020187012859A KR 20187012859 A KR20187012859 A KR 20187012859A KR 20180053419 A KR20180053419 A KR 20180053419A
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atoh1
oligonucleotide
antisense
polynucleotide
nucleic acid
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Korean (ko)
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조셉 콜라드
올가 크로코바 셔만
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큐알엔에이, 인크.
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KR1020187012859A 2010-05-26 2011-05-25 무조(無調)의 동소체 1 (atoh1)에 대한 자연 안티센스 전사체의 저해에 의한 atoh1 관련된 질환의 치료 Ceased KR20180053419A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34865610P 2010-05-26 2010-05-26
US61/348,656 2010-05-26
PCT/US2011/037833 WO2011150005A2 (en) 2010-05-26 2011-05-25 Treatment of atonal homolog 1 (atoh1) related diseases by inhibition of natural antisense transcript to atoh1

Related Parent Applications (1)

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KR1020127031569A Division KR101857090B1 (ko) 2010-05-26 2011-05-25 무조(無調)의 동소체 1 (atoh1)에 대한 자연 안티센스 전사체의 저해에 의한 atoh1 관련된 질환의 치료

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KR20180053419A true KR20180053419A (ko) 2018-05-21

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KR1020187012859A Ceased KR20180053419A (ko) 2010-05-26 2011-05-25 무조(無調)의 동소체 1 (atoh1)에 대한 자연 안티센스 전사체의 저해에 의한 atoh1 관련된 질환의 치료
KR1020127031569A Active KR101857090B1 (ko) 2010-05-26 2011-05-25 무조(無調)의 동소체 1 (atoh1)에 대한 자연 안티센스 전사체의 저해에 의한 atoh1 관련된 질환의 치료

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US (4) US8895528B2 (enExample)
EP (2) EP3299464B1 (enExample)
JP (2) JP5973996B2 (enExample)
KR (2) KR20180053419A (enExample)
CN (2) CN107412251A (enExample)
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EP3299464B1 (en) 2010-05-26 2019-10-02 CuRNA, Inc. Treatment of atonal homolog 1 (atoh1) related diseases by inhibition of natural antisense transcript to atoh1
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EP2850188A4 (en) 2012-05-16 2016-01-20 Rana Therapeutics Inc COMPOSITIONS AND METHOD FOR MODULATING THE EXPRESSION OF THE HEMOGLOBIN GENE FAMILIES
US10837014B2 (en) 2012-05-16 2020-11-17 Translate Bio Ma, Inc. Compositions and methods for modulating SMN gene family expression
JP2015518713A (ja) 2012-05-16 2015-07-06 ラナ セラピューティクス インコーポレイテッド Ｕｔｒｎ発現を調節するための組成物及び方法
EA201492114A1 (ru) 2012-05-16 2015-04-30 Рана Терапьютикс, Инк. Композиции и способы для модулирования экспрессии генов
EP3970725B1 (en) 2012-09-07 2025-08-20 Massachusetts Eye & Ear Infirmary A gamma secretase inhibitor for treating hearing loss
AU2013337422A1 (en) * 2012-11-02 2015-05-07 Genesys Research Institute Compositions and methods for auditory therapy
US9572815B2 (en) 2013-03-15 2017-02-21 St. Jude Children's Research Hospital Methods and compositions of p27KIP1 transcriptional modulators
WO2016022776A2 (en) * 2014-08-06 2016-02-11 Massachusetts Eye And Ear Infirmary Increasing atoh1 life to drive sensorineural hair cell differentiantion
TWI710635B (zh) * 2014-10-09 2020-11-21 美商珍維克公司 編碼人類無調同源物-1(hath1)之腺病毒載體
US10858650B2 (en) 2014-10-30 2020-12-08 The General Hospital Corporation Methods for modulating ATRX-dependent gene repression
WO2016149455A2 (en) 2015-03-17 2016-09-22 The General Hospital Corporation The rna interactome of polycomb repressive complex 1 (prc1)
CN108137595B (zh) 2015-06-18 2021-04-20 听治疗有限责任公司 预防和治疗听力损失的方法和组合物
WO2017096233A1 (en) 2015-12-04 2017-06-08 Massachusetts Eye And Ear Infirmary Treatment of hearing loss by inhibition of casein kinase 1
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