KR20110005320A - S1p 수용체 아고니스트 및 당 알콜을 포함하는 고형 제약 조성물 - Google Patents

S1p 수용체 아고니스트 및 당 알콜을 포함하는 고형 제약 조성물 Download PDF

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Publication number
KR20110005320A
KR20110005320A KR1020107029859A KR20107029859A KR20110005320A KR 20110005320 A KR20110005320 A KR 20110005320A KR 1020107029859 A KR1020107029859 A KR 1020107029859A KR 20107029859 A KR20107029859 A KR 20107029859A KR 20110005320 A KR20110005320 A KR 20110005320A
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South Korea
Prior art keywords
receptor agonist
composition
alkyl
mixing
sugar alcohol
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Ceased
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KR1020107029859A
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English (en)
Korean (ko)
Inventor
도모유끼 오오무라
마드후수드한 푸디페띠
알랜 에드워드 로이스
콜린 루에거
마사끼 사사끼
도꾸히로 다무라
Original Assignee
노파르티스 아게
미쯔비시 웰 파마 가부시키가이샤
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Application filed by 노파르티스 아게, 미쯔비시 웰 파마 가부시키가이샤 filed Critical 노파르티스 아게
Publication of KR20110005320A publication Critical patent/KR20110005320A/ko
Ceased legal-status Critical Current

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
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    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
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    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
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    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020107029859A 2003-04-08 2004-04-06 S1p 수용체 아고니스트 및 당 알콜을 포함하는 고형 제약 조성물 Ceased KR20110005320A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46121503P 2003-04-08 2003-04-08
US60/461,215 2003-04-08

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020057019066A Division KR20050121712A (ko) 2003-04-08 2004-04-06 유기 화합물

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020127019448A Division KR101367574B1 (ko) 2003-04-08 2004-04-06 S1p 수용체 아고니스트 및 당 알콜을 포함하는 고형 제약 조성물

Publications (1)

Publication Number Publication Date
KR20110005320A true KR20110005320A (ko) 2011-01-17

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ID=32326722

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Application Number Title Priority Date Filing Date
KR1020107029859A Ceased KR20110005320A (ko) 2003-04-08 2004-04-06 S1p 수용체 아고니스트 및 당 알콜을 포함하는 고형 제약 조성물
KR1020127019448A Expired - Lifetime KR101367574B1 (ko) 2003-04-08 2004-04-06 S1p 수용체 아고니스트 및 당 알콜을 포함하는 고형 제약 조성물
KR1020057019066A Ceased KR20050121712A (ko) 2003-04-08 2004-04-06 유기 화합물

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1020127019448A Expired - Lifetime KR101367574B1 (ko) 2003-04-08 2004-04-06 S1p 수용체 아고니스트 및 당 알콜을 포함하는 고형 제약 조성물
KR1020057019066A Ceased KR20050121712A (ko) 2003-04-08 2004-04-06 유기 화합물

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