KR102359214B1 - 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체 - Google Patents
폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체 Download PDFInfo
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- KR102359214B1 KR102359214B1 KR1020167030879A KR20167030879A KR102359214B1 KR 102359214 B1 KR102359214 B1 KR 102359214B1 KR 1020167030879 A KR1020167030879 A KR 1020167030879A KR 20167030879 A KR20167030879 A KR 20167030879A KR 102359214 B1 KR102359214 B1 KR 102359214B1
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- Prior art keywords
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- methyl
- dianhydrogalactitol
- phenyl
- inhibitors
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- BTMGLVPEZNZOIG-UHFFFAOYSA-N CC(C1[O]2C1)(C(C)(C1OC1)OC2=O)OC(C)=O Chemical compound CC(C1[O]2C1)(C(C)(C1OC1)OC2=O)OC(C)=O BTMGLVPEZNZOIG-UHFFFAOYSA-N 0.000 description 1
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020227003524A KR102456088B1 (ko) | 2014-04-04 | 2015-04-06 | 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461975587P | 2014-04-04 | 2014-04-04 | |
| US61/975,587 | 2014-04-04 | ||
| US201462062246P | 2014-10-10 | 2014-10-10 | |
| US62/062,246 | 2014-10-10 | ||
| PCT/US2015/024462 WO2015154064A2 (en) | 2014-04-04 | 2015-04-06 | Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020227003524A Division KR102456088B1 (ko) | 2014-04-04 | 2015-04-06 | 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20160132130A KR20160132130A (ko) | 2016-11-16 |
| KR102359214B1 true KR102359214B1 (ko) | 2022-02-07 |
Family
ID=54241453
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167030879A Expired - Fee Related KR102359214B1 (ko) | 2014-04-04 | 2015-04-06 | 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체 |
| KR1020227003524A Active KR102456088B1 (ko) | 2014-04-04 | 2015-04-06 | 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020227003524A Active KR102456088B1 (ko) | 2014-04-04 | 2015-04-06 | 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11541027B2 (https=) |
| EP (2) | EP3125920B1 (https=) |
| JP (2) | JP6783224B2 (https=) |
| KR (2) | KR102359214B1 (https=) |
| CN (1) | CN106659765B (https=) |
| AU (2) | AU2015240465B2 (https=) |
| CA (1) | CA2946538A1 (https=) |
| CL (1) | CL2016002514A1 (https=) |
| IL (1) | IL248189B (https=) |
| MX (1) | MX385778B (https=) |
| SG (1) | SG11201608303QA (https=) |
| TW (1) | TW201713326A (https=) |
| WO (2) | WO2015154064A2 (https=) |
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| US10745467B2 (en) | 2010-03-26 | 2020-08-18 | The Trustees Of Dartmouth College | VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders |
| US20150231215A1 (en) | 2012-06-22 | 2015-08-20 | Randolph J. Noelle | VISTA Antagonist and Methods of Use |
| MX374075B (es) * | 2010-03-26 | 2025-03-05 | Dartmouth College | Proteina mediadora de celula t regulatoria vista, agentes de enlace de vista y uso de los mismos. |
| US9890215B2 (en) | 2012-06-22 | 2018-02-13 | King's College London | Vista modulators for diagnosis and treatment of cancer |
| JP6285923B2 (ja) | 2012-06-22 | 2018-02-28 | トラスティーズ・オブ・ダートマス・カレッジ | 新規VISTA−Igコンストラクト及び自己免疫、アレルギー性及び炎症性障害の処置のためのVISTA−Igの使用 |
| US9381244B2 (en) | 2012-09-07 | 2016-07-05 | King's College London | VISTA modulators for diagnosis and treatment of cancer |
| US11014987B2 (en) | 2013-12-24 | 2021-05-25 | Janssen Pharmaceutics Nv | Anti-vista antibodies and fragments, uses thereof, and methods of identifying same |
| WO2015097536A2 (en) | 2013-12-24 | 2015-07-02 | Janssen Pharmaceutical Nv | Anti-vista antibodies and fragments |
| US11123426B2 (en) | 2014-06-11 | 2021-09-21 | The Trustees Of Dartmouth College | Use of vista agonists and antagonists to suppress or enhance humoral immunity |
| IL252192B2 (en) * | 2014-11-10 | 2024-03-01 | Del Mar Pharmaceuticals | Dianhydrogalactitol together with radiation to treat non-small-cell carcinoma of the lung and glioblastoma multiforme |
| CA2969730A1 (en) | 2014-12-05 | 2016-06-09 | Immunext, Inc. | Identification of vsig8 as the putative vista receptor and its use thereof to produce vista/vsig8 modulators |
| CA2990360C (en) | 2015-06-24 | 2024-02-13 | Janssen Pharmaceutica Nv | Anti-vista antibodies and fragments |
| WO2017042634A2 (en) * | 2015-09-10 | 2017-03-16 | Del Mar Pharmaceuticals | Use of dianhydrogalactitol or derivatives and analogs thereof for treatment of non-small-cell lung carcinoma, glioblastoma, and ovarian carcinoma by induction of dna damage and stalling of cell cycle |
| US11784303B2 (en) | 2015-09-22 | 2023-10-10 | Ii-Vi Delaware, Inc. | Immobilized chalcogen and use thereof in a rechargeable battery |
| US12155058B2 (en) | 2015-09-22 | 2024-11-26 | Ii-Vi Delaware, Inc. | Immobilized chalcogen comprising a chalcogen element, an electrically conductive material, and hydrophilic membrane gate and use thereof in a rechargeable battery |
| US11588149B2 (en) | 2015-09-22 | 2023-02-21 | Ii-Vi Delaware, Inc. | Immobilized selenium in a porous carbon with the presence of oxygen, a method of making, and uses of immobilized selenium in a rechargeable battery |
| US12159994B2 (en) | 2015-09-22 | 2024-12-03 | Ii-Vi Delaware, Inc. | Immobilized selenium, a method of making, and uses of immobilized selenium in a rechargeable battery |
| WO2017075052A1 (en) * | 2015-10-28 | 2017-05-04 | Delmar Pharmaceuticals, Inc. | Use of dianhydrogalactitol or derivatives or analogs thereof for treatment of pediatric central nervous system malignancies |
| WO2017137830A1 (en) | 2016-02-12 | 2017-08-17 | Janssen Pharmaceutica Nv | Anti-vista (b7h5) antibodies |
| KR20230119259A (ko) | 2016-04-15 | 2023-08-16 | 이뮤넥스트, 인크. | 항-인간 vista 항체 및 이의 용도 |
| US11870059B2 (en) | 2017-02-16 | 2024-01-09 | Consejo Superior De Investigaciones Cientificas (Csic) | Immobilized selenium in a porous carbon with the presence of oxygen, a method of making, and uses of immobilized selenium in a rechargeable battery |
| WO2018160758A1 (en) * | 2017-02-28 | 2018-09-07 | Bacha Jeffrey A | Use of dianhydrogalactitol or analogs and derivatives in combination with a p53 modulator or a parp inhibitor |
| WO2018165520A1 (en) | 2017-03-10 | 2018-09-13 | Vps-3, Inc. | Metalloenzyme inhibitor compounds |
| CN106947821B (zh) * | 2017-04-11 | 2020-06-30 | 成都望路医药技术有限公司 | 用于诊治结肠腺癌的生物标志物 |
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| AU2015240465A1 (en) | 2016-10-27 |
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