KR100623333B1 - 향자궁성 효과가 없는 에스트로겐-유사 기관-선택적의약으로서의 붓꽃 식물, 시미시푸가 라세모사의 추출물및 텍토리게닌의 용도 - Google Patents
향자궁성 효과가 없는 에스트로겐-유사 기관-선택적의약으로서의 붓꽃 식물, 시미시푸가 라세모사의 추출물및 텍토리게닌의 용도 Download PDFInfo
- Publication number
- KR100623333B1 KR100623333B1 KR1020007008724A KR20007008724A KR100623333B1 KR 100623333 B1 KR100623333 B1 KR 100623333B1 KR 1020007008724 A KR1020007008724 A KR 1020007008724A KR 20007008724 A KR20007008724 A KR 20007008724A KR 100623333 B1 KR100623333 B1 KR 100623333B1
- Authority
- KR
- South Korea
- Prior art keywords
- estrogen
- racemosa
- extract
- estradiol
- tectorigenin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- OBBCRPUNCUPUOS-UHFFFAOYSA-N COc(c(O)c(c(OC=C1c(cc2)ccc2O)c2)C1=O)c2O Chemical compound COc(c(O)c(c(OC=C1c(cc2)ccc2O)c2)C1=O)c2O OBBCRPUNCUPUOS-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19812204A DE19812204A1 (de) | 1998-03-19 | 1998-03-19 | Verwendung von Extrakten aus Cimicifuga racemosa und Belamcanda sinensis als estrogenartiges organselektives Arzneimittel ohne uterotrope Wirkung |
| DE19812204.7 | 1998-03-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20010040829A KR20010040829A (ko) | 2001-05-15 |
| KR100623333B1 true KR100623333B1 (ko) | 2006-12-05 |
Family
ID=7861630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020007008724A Expired - Fee Related KR100623333B1 (ko) | 1998-03-19 | 1999-03-19 | 향자궁성 효과가 없는 에스트로겐-유사 기관-선택적의약으로서의 붓꽃 식물, 시미시푸가 라세모사의 추출물및 텍토리게닌의 용도 |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1064009B2 (https=) |
| JP (2) | JP2002506827A (https=) |
| KR (1) | KR100623333B1 (https=) |
| CN (2) | CN100581541C (https=) |
| AT (1) | ATE225182T1 (https=) |
| AU (1) | AU755900C (https=) |
| BR (1) | BR9908256A (https=) |
| CA (1) | CA2321444C (https=) |
| CZ (1) | CZ292684B6 (https=) |
| DE (2) | DE19812204A1 (https=) |
| DK (1) | DK1064009T4 (https=) |
| ES (1) | ES2184427T5 (https=) |
| HU (1) | HU227694B1 (https=) |
| MX (1) | MXPA00007986A (https=) |
| PL (1) | PL194096B1 (https=) |
| PT (1) | PT1064009E (https=) |
| RU (2) | RU2228188C2 (https=) |
| SE (1) | SE1064009T4 (https=) |
| TR (1) | TR200002686T2 (https=) |
| WO (1) | WO1999047149A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100928013B1 (ko) * | 2008-01-25 | 2009-11-24 | 이화여자대학교 산학협력단 | 범부채 추출물을 이용한 돌피의 생장 촉진방법 및 이방법을 적용한 중금속 오염 토양의 정화방법 |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000302667A (ja) * | 1999-04-23 | 2000-10-31 | Kobe Tennenbutsu Kagaku Kk | 豊胸促進剤 |
| CA2414247C (en) * | 2000-06-29 | 2012-11-27 | Quick-Med Technologies, Inc. | Cosmetic composition and method comprising a hydroxamate mmpi and a triterpenoid glycoside |
| TWI303990B (en) | 2000-10-17 | 2008-12-11 | Pfizer Prod Inc | New use of estrogen agonists/antagonists for improving vascular health |
| DE10054641A1 (de) | 2000-11-03 | 2002-05-16 | Schaper & Bruemmer Gmbh | Verwendung einer Zubereitung von Cimicifuga racemosa |
| DE10123503A1 (de) * | 2001-05-15 | 2002-11-21 | Bionorica Ag | Verwendung von Extrakten und Zubereitungen aus Irisgewächsen und Tectorigenin als organselektives Arzneimittel zur Behandlung von sexualhormon-abhängigen Erkrankungen des Urogenitaltraktes |
| DE10127897B4 (de) * | 2001-06-08 | 2006-04-20 | Bionorica Ag | Manteltablette mit Pflanzentrockenextrakten |
| DE10146159A1 (de) * | 2001-09-19 | 2003-04-10 | Bionorica Ag | Verwendung von Extrakten aus Cimicifuga-Arten als organselektives Arzneimittel zur Behandlung von sexualhormonabhängigen Erkrankungen des Urogenitaltraktes |
| EP1325681A1 (en) * | 2001-12-11 | 2003-07-09 | Société des Produits Nestlé S.A. | Composition for promotion of bone growth and maintenance of bone health |
| DE10206390A1 (de) * | 2002-02-15 | 2003-08-28 | Bionorica Ag | Verwendung von selektiv den Estrogenrezeptor beta modulierenden phytoestrogenhaltigen Extrakten |
| JP4605984B2 (ja) * | 2002-12-20 | 2011-01-05 | アサヒビール株式会社 | ストレス緩和剤 |
| DE602004020463D1 (de) * | 2003-05-15 | 2009-05-20 | Chengdu Dikang Pharmaceutical | Isoflavonderivative von tectoridin, deren herstellung und antivirale medikamente, die diese als wirksame bestandteile enthalten |
| EP1588739A1 (en) * | 2004-04-23 | 2005-10-26 | Schaper & Brümmer Gmbh & Co. Kg | Composition comprising a combination of calcium, Cimicifugae racemosae rhizoma and vitamin D and its use as a pharmaceutical in conditions or disorders associated with or resulting from calcium deficiency or as a nutritional supplement |
| EP1591143A1 (en) * | 2004-04-26 | 2005-11-02 | Schaper & Brümmer Gmbh & Co. Kg | Composition comprising a combination of Calcium, Cimicifugae racemosae rhizoma and vitamin D and its use as a pharmaceutical in conditions or disorders associated with or resulting from calcium deficiency or as a nutritional supplement |
| US7887851B2 (en) | 2004-06-07 | 2011-02-15 | Kao Corporation | Aromatase activator |
| CN100381435C (zh) * | 2005-03-24 | 2008-04-16 | 深圳海王药业有限公司 | 射干总黄酮提取物及其制备方法和其在药物制备中的应用 |
| EP1745796A1 (de) | 2005-07-19 | 2007-01-24 | Bionorica Research GmbH | Kombinationspräparat insbesondere zur Therapie des Prostatakarzinoms |
| CN101057854B (zh) * | 2006-05-31 | 2010-05-12 | 南京大学 | 升麻环菠萝蜜烷型三萜类化合物在抗骨质疏松及更年期综合症的用途 |
| DE102007044916A1 (de) | 2007-09-19 | 2009-04-23 | Bionorica Ag | Kosmetische oder dermatologische Zusammensetzung zur topischen Verwendung |
| CN101797265A (zh) * | 2010-04-09 | 2010-08-11 | 中国人民解放军第二军医大学 | 射干总异黄酮或异黄酮类化合物在制备防治妇女病的药物或食品中的应用 |
| EP2545932A1 (de) | 2011-07-12 | 2013-01-16 | Bionorica Se | Ausgewählte Cimicifuga-Fraktionen zur Behandlung von Osteoporose |
| WO2013007807A1 (de) | 2011-07-12 | 2013-01-17 | Bionorica Se | Ausgewählte cimicifuga-fraktionen zur behandlung von osteoporose |
| EP2620155A1 (de) | 2012-01-30 | 2013-07-31 | Bionorica SE | Arzneimittel enthaltend Cimicifuga zur Anwendung bei der Behandlung von Sarkopenie und Herzmuskelschwäche |
| CN102525907B (zh) * | 2012-02-22 | 2013-06-05 | 四川省中医药科学院 | 鸢尾苷元磺酸钠注射液 |
| CN102631363A (zh) * | 2012-04-11 | 2012-08-15 | 李超生 | 鸢尾苷在制备防治骨质疏松症的药物中的应用 |
| KR20150018831A (ko) * | 2012-06-22 | 2015-02-24 | 골든 바이오테크놀러지 코포레이션 | 동맥경화성 혈관 질환을 치료하기 위한 방법 및 조성물 |
| AU2013285492B2 (en) | 2012-07-03 | 2015-11-12 | Max Zeller Soehne Ag | Novel pharmacological use of Cimicifuga extract |
| JP2014091706A (ja) * | 2012-11-02 | 2014-05-19 | Kao Corp | Glp−1分泌促進剤 |
| KR101965849B1 (ko) * | 2017-03-07 | 2019-04-04 | 주식회사 엘지생활건강 | 텍토리게닌 7-0-자일로실글루코시드를 포함하는 여성 갱년기 증상 완화용 조성물 |
| KR101964841B1 (ko) * | 2017-03-07 | 2019-08-07 | 주식회사 엘지생활건강 | 여성 갱년기 증상 개선용 조성물 |
| TWI761372B (zh) * | 2017-09-22 | 2022-04-21 | 日商東洋新藥股份有限公司 | 組合物 |
| WO2020141083A1 (en) | 2018-12-31 | 2020-07-09 | Max Zeller Soehne Ag | Combination of cimicifuga and petasites extracts for anticancer therapy and prophylaxis |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6330417A (ja) * | 1986-07-23 | 1988-02-09 | Tsumura Juntendo Inc | 抗アレルギ−剤 |
| US5411733A (en) * | 1992-04-27 | 1995-05-02 | Hozumi; Toyoharu | Antiviral agent containing crude drug |
| RU2012348C1 (ru) * | 1992-10-30 | 1994-05-15 | Анна Геннадиевна Пономарева | Сбор лекарственных трав, обладающий общеукрепляющим действием, "нежность", "осень", "наташа" |
| ES2132855T3 (es) * | 1995-09-07 | 1999-08-16 | Oreal | Extracto de iridaceas y composiciones que lo contienen. |
| KR19990067010A (ko) * | 1995-10-23 | 1999-08-16 | 오스테오스크린, 인코포레이티드 | 골결핍 상태의 치료용 조성물 및 그 치료방법 |
| JPH09301884A (ja) * | 1996-05-15 | 1997-11-25 | Ichimaru Pharcos Co Ltd | ヒオウギ抽出物及びα−ヒドロキシ酸を含有するテストステロン5α−リダクターゼ阻害剤とその応用 |
| JPH107580A (ja) * | 1996-06-15 | 1998-01-13 | Michio Yoshida | コラゲナ−ゼ阻害剤 |
| JP3665848B2 (ja) * | 1996-09-18 | 2005-06-29 | 木村 幸代 | ヒメヒオウギズイセン球根抽出液の発酵飲料及びその製造方法 |
| US5753266A (en) * | 1996-12-03 | 1998-05-19 | Youssefyeh; Parvin | Safflower seed powder compositions for the treatment of rheumatoid based arthritic diseases |
| DE19652183C1 (de) * | 1996-12-14 | 1998-02-12 | Schaper & Bruemmer Gmbh | Verwendung eines Extraktes aus Cimicifuga racemosa |
| RU2114629C1 (ru) * | 1997-04-10 | 1998-07-10 | Бабаскина Людмила Ивановна | Сбор лекарственных трав, обладающий общеукрепляющим и нормализующим гормональный статус в климактерическом периоде действием |
-
1998
- 1998-03-19 DE DE19812204A patent/DE19812204A1/de not_active Withdrawn
-
1999
- 1999-03-19 TR TR2000/02686T patent/TR200002686T2/xx unknown
- 1999-03-19 CN CN03145494A patent/CN100581541C/zh not_active Expired - Fee Related
- 1999-03-19 PT PT99913282T patent/PT1064009E/pt unknown
- 1999-03-19 BR BR9908256-0A patent/BR9908256A/pt not_active IP Right Cessation
- 1999-03-19 MX MXPA00007986A patent/MXPA00007986A/es active IP Right Grant
- 1999-03-19 RU RU2000126476/15A patent/RU2228188C2/ru not_active IP Right Cessation
- 1999-03-19 ES ES99913282T patent/ES2184427T5/es not_active Expired - Lifetime
- 1999-03-19 JP JP2000536389A patent/JP2002506827A/ja not_active Withdrawn
- 1999-03-19 EP EP99913282A patent/EP1064009B2/de not_active Expired - Lifetime
- 1999-03-19 SE SE99913282T patent/SE1064009T4/xx unknown
- 1999-03-19 DE DE59902932T patent/DE59902932D1/de not_active Expired - Lifetime
- 1999-03-19 AU AU31466/99A patent/AU755900C/en not_active Ceased
- 1999-03-19 CZ CZ20002810A patent/CZ292684B6/cs not_active IP Right Cessation
- 1999-03-19 RU RU2003137324/15A patent/RU2263505C2/ru not_active IP Right Cessation
- 1999-03-19 DK DK99913282T patent/DK1064009T4/da active
- 1999-03-19 AT AT99913282T patent/ATE225182T1/de active
- 1999-03-19 WO PCT/EP1999/001860 patent/WO1999047149A1/de not_active Ceased
- 1999-03-19 HU HU0200921A patent/HU227694B1/hu not_active IP Right Cessation
- 1999-03-19 CN CNB998041238A patent/CN100444867C/zh not_active Expired - Fee Related
- 1999-03-19 CA CA2321444A patent/CA2321444C/en not_active Expired - Fee Related
- 1999-03-19 KR KR1020007008724A patent/KR100623333B1/ko not_active Expired - Fee Related
- 1999-03-19 PL PL99342486A patent/PL194096B1/pl not_active IP Right Cessation
-
2010
- 2010-03-01 JP JP2010044419A patent/JP2010132699A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100928013B1 (ko) * | 2008-01-25 | 2009-11-24 | 이화여자대학교 산학협력단 | 범부채 추출물을 이용한 돌피의 생장 촉진방법 및 이방법을 적용한 중금속 오염 토양의 정화방법 |
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