DE19812204A1 - Verwendung von Extrakten aus Cimicifuga racemosa und Belamcanda sinensis als estrogenartiges organselektives Arzneimittel ohne uterotrope Wirkung - Google Patents

Verwendung von Extrakten aus Cimicifuga racemosa und Belamcanda sinensis als estrogenartiges organselektives Arzneimittel ohne uterotrope Wirkung

Info

Publication number
DE19812204A1
DE19812204A1 DE19812204A DE19812204A DE19812204A1 DE 19812204 A1 DE19812204 A1 DE 19812204A1 DE 19812204 A DE19812204 A DE 19812204A DE 19812204 A DE19812204 A DE 19812204A DE 19812204 A1 DE19812204 A1 DE 19812204A1
Authority
DE
Germany
Prior art keywords
estrogen
extracts
organ
cimicifuga
cimicifuga racemosa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19812204A
Other languages
German (de)
English (en)
Inventor
Wolfgang Wuttke
Hubertus Jarry
Volker Christoffel
Barbara Spengler
Michael Popp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bionorica SE
Original Assignee
Plantamed Arzneimittel GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7861630&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE19812204(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Plantamed Arzneimittel GmbH filed Critical Plantamed Arzneimittel GmbH
Priority to DE19812204A priority Critical patent/DE19812204A1/de
Priority to DK99913282T priority patent/DK1064009T4/da
Priority to DE59902932T priority patent/DE59902932D1/de
Priority to MXPA00007986A priority patent/MXPA00007986A/es
Priority to TR2000/02686T priority patent/TR200002686T2/xx
Priority to PCT/EP1999/001860 priority patent/WO1999047149A1/de
Priority to HK01104552.1A priority patent/HK1035660B/xx
Priority to BR9908256-0A priority patent/BR9908256A/pt
Priority to CNB998041238A priority patent/CN100444867C/zh
Priority to EP99913282A priority patent/EP1064009B2/de
Priority to PT99913282T priority patent/PT1064009E/pt
Priority to JP2000536389A priority patent/JP2002506827A/ja
Priority to RU2000126476/15A priority patent/RU2228188C2/ru
Priority to KR1020007008724A priority patent/KR100623333B1/ko
Priority to AT99913282T priority patent/ATE225182T1/de
Priority to AU31466/99A priority patent/AU755900C/en
Priority to RU2003137324/15A priority patent/RU2263505C2/ru
Priority to CA2321444A priority patent/CA2321444C/en
Priority to ES99913282T priority patent/ES2184427T5/es
Priority to PL99342486A priority patent/PL194096B1/pl
Priority to CN03145494A priority patent/CN100581541C/zh
Priority to CZ20002810A priority patent/CZ292684B6/cs
Priority to SE99913282T priority patent/SE1064009T4/xx
Priority to HU0200921A priority patent/HU227694B1/hu
Publication of DE19812204A1 publication Critical patent/DE19812204A1/de
Priority to US10/951,583 priority patent/US20050037100A1/en
Priority to US11/618,304 priority patent/US20070122503A1/en
Priority to JP2010044419A priority patent/JP2010132699A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE19812204A 1998-03-19 1998-03-19 Verwendung von Extrakten aus Cimicifuga racemosa und Belamcanda sinensis als estrogenartiges organselektives Arzneimittel ohne uterotrope Wirkung Withdrawn DE19812204A1 (de)

Priority Applications (27)

Application Number Priority Date Filing Date Title
DE19812204A DE19812204A1 (de) 1998-03-19 1998-03-19 Verwendung von Extrakten aus Cimicifuga racemosa und Belamcanda sinensis als estrogenartiges organselektives Arzneimittel ohne uterotrope Wirkung
HU0200921A HU227694B1 (en) 1998-03-19 1999-03-19 Utilization of extracts from iris plants, cimicifuga racemosa and tectorigenin as an estrogen-like organ-selective medicament without uterotropic effects
RU2000126476/15A RU2228188C2 (ru) 1998-03-19 1999-03-19 Применение экстрактов семейства iridaceae и cimicifuga racemosa и текторигенина в качестве действующего по типу эстрогена орган-селективного лекарственного препарата, не имеющего утеротропного эффекта
AT99913282T ATE225182T1 (de) 1998-03-19 1999-03-19 Verwendung von extrakten aus irisgewächsen und cimicifuga racemosa und tectorigenin als östrogenartiges organselektives arzneimittel ohne uterotrope wirkung
MXPA00007986A MXPA00007986A (es) 1998-03-19 1999-03-19 Utilizacion de extractos de plantas de iris, cimicifuga racemosa y tectorigenina como un medicamento organo-selectivo similar al estrogeno, sin efectos uterotroficos.
TR2000/02686T TR200002686T2 (tr) 1998-03-19 1999-03-19 Iridaceae ve Cimicifuga racemosadan elde edilen ekstrelerin ve tectorigeninin hiçbir uterotropik etkiye sahip olmayan bir estrojen-tipi, organ-seçiçi ilaç olarak kullanımı
PCT/EP1999/001860 WO1999047149A1 (de) 1998-03-19 1999-03-19 Verwendung von extrakten aus irisgewächsen und cimicifuga racemosa und tectorigenin als estrogenartiges organselektives arzneimittel ohne uterotrope wirkung
HK01104552.1A HK1035660B (en) 1998-03-19 1999-03-19 Utilization of extracts from iris plants, cimicifuga racemosa and tectorigenin as an estrogen-like organ-selective medicament without uterotropic effects
BR9908256-0A BR9908256A (pt) 1998-03-19 1999-03-19 Uso de extratos obtidos de iridáceas e cimicifuga racemosa e de tectorigenin como medicamento organoseletivo do tipo estrogênio não possuindo efeito uterotrópico
CNB998041238A CN100444867C (zh) 1998-03-19 1999-03-19 含有鸢尾黄素的射干提取物在制备雌激素型对器官有选择性而无趋子宫作用的药物中的应用
EP99913282A EP1064009B2 (de) 1998-03-19 1999-03-19 Verwendung von extrakten aus irisgewächsen und cimicifuga racemosa und tectorigenin als östrogenartiges organselektives arzneimittel ohne uterotrope wirkung
PT99913282T PT1064009E (pt) 1998-03-19 1999-03-19 Utilizacao de extractos obtidos de iridaceas e cimicifuga racemosa e de tectorigenina como medicamento organosselectivo do tipo do estrogeneo sem efeito uterotropico
JP2000536389A JP2002506827A (ja) 1998-03-19 1999-03-19 向子宮性作用を持たない、エストロゲン型の器官選択性薬剤としての、アヤメ科及びシミシフガ・ラセモサ(Cimicifugaracemosa)の抽出物、並びにテクトリゲニンの使用
DK99913282T DK1064009T4 (da) 1998-03-19 1999-03-19 Anvendelse af ekstrakter af irisplanter og Cimicifuga racemosa og tectorigenin som estrogenagtigt organselektivt lægemiddel uden uterotrop virkning
KR1020007008724A KR100623333B1 (ko) 1998-03-19 1999-03-19 향자궁성 효과가 없는 에스트로겐-유사 기관-선택적의약으로서의 붓꽃 식물, 시미시푸가 라세모사의 추출물및 텍토리게닌의 용도
DE59902932T DE59902932D1 (de) 1998-03-19 1999-03-19 Verwendung von extrakten aus irisgewächsen und cimicifuga racemosa und tectorigenin als östrogenartiges organselektives arzneimittel ohne uterotrope wirkung
AU31466/99A AU755900C (en) 1998-03-19 1999-03-19 Utilization of extracts from iris plants, cimicifuga racemosa and tectorigenin as an estrogen-like organ-selective medicament without uterotropic effects
RU2003137324/15A RU2263505C2 (ru) 1998-03-19 1999-03-19 Применение экстракта belamcanda chinensis в качестве подобного эстрогену орган-селективного лекарственного препарата, не имеющего утеротропного эффекта
CA2321444A CA2321444C (en) 1998-03-19 1999-03-19 Utilization of extracts from iris plants, cimicifuga racemosa and tectorigenin as an estrogen-like organ-selective medicament without uterotropic effects
ES99913282T ES2184427T5 (es) 1998-03-19 1999-03-19 Uso de extractos obtenidos de iridaceas y de cimifuga racemosa y de tectorigenina como medicamento organoselectivo de tipo estrogenico sin poseer efecto uterotropico.
PL99342486A PL194096B1 (pl) 1998-03-19 1999-03-19 Zastosowanie wyciągów z roślin irysa, Cimicifuga racemosa i wyciągów zawierających tektorygeninę i/lub glikozyd tektorygeniny albo wyciągów wzbogaconych tektorygeniną i/lub glikozydem tektorygeniny do wytwarzania estrogenoidowego organoselektywnego środka leczniczego
CN03145494A CN100581541C (zh) 1998-03-19 1999-03-19 总状花升麻提取物在生产用于抑制黄体生成素活性的雌激素型器官选择性药物中的用途
CZ20002810A CZ292684B6 (cs) 1998-03-19 1999-03-19 Použití extraktů rostlin Iris a Cimicifuga racemosa a tektorigeninu jako estrogenního organoselektivního léčiva bez uterotropního účinku
SE99913282T SE1064009T4 (sv) 1998-03-19 1999-03-19 Anvaendning av extract av irisvaexter och Cimicifuga racemosa och tektorigenin saesom oestrogenartat organselektivt laekemedel utan uterotrop verkan
US10/951,583 US20050037100A1 (en) 1998-03-19 2004-09-27 Utilization of extracts from iris plants, cimicifuga racemose and tectorigenin as an estrogen-like organ-selective medicament without uterotropic
US11/618,304 US20070122503A1 (en) 1998-03-19 2006-12-29 Use of extracts from cimicifuga racemosa and of tectorigenin as an estrogen-type, organoselective medicament having no uterotrophic effect
JP2010044419A JP2010132699A (ja) 1998-03-19 2010-03-01 向子宮性作用を持たない、エストロゲン型の器官選択性薬剤としての、アヤメ科及びシミシフガ・ラセモサ(Cimicifugaracemosa)の抽出物、並びにテクトリゲニンの使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19812204A DE19812204A1 (de) 1998-03-19 1998-03-19 Verwendung von Extrakten aus Cimicifuga racemosa und Belamcanda sinensis als estrogenartiges organselektives Arzneimittel ohne uterotrope Wirkung

Publications (1)

Publication Number Publication Date
DE19812204A1 true DE19812204A1 (de) 1999-11-04

Family

ID=7861630

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19812204A Withdrawn DE19812204A1 (de) 1998-03-19 1998-03-19 Verwendung von Extrakten aus Cimicifuga racemosa und Belamcanda sinensis als estrogenartiges organselektives Arzneimittel ohne uterotrope Wirkung
DE59902932T Expired - Lifetime DE59902932D1 (de) 1998-03-19 1999-03-19 Verwendung von extrakten aus irisgewächsen und cimicifuga racemosa und tectorigenin als östrogenartiges organselektives arzneimittel ohne uterotrope wirkung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE59902932T Expired - Lifetime DE59902932D1 (de) 1998-03-19 1999-03-19 Verwendung von extrakten aus irisgewächsen und cimicifuga racemosa und tectorigenin als östrogenartiges organselektives arzneimittel ohne uterotrope wirkung

Country Status (20)

Country Link
EP (1) EP1064009B2 (https=)
JP (2) JP2002506827A (https=)
KR (1) KR100623333B1 (https=)
CN (2) CN100581541C (https=)
AT (1) ATE225182T1 (https=)
AU (1) AU755900C (https=)
BR (1) BR9908256A (https=)
CA (1) CA2321444C (https=)
CZ (1) CZ292684B6 (https=)
DE (2) DE19812204A1 (https=)
DK (1) DK1064009T4 (https=)
ES (1) ES2184427T5 (https=)
HU (1) HU227694B1 (https=)
MX (1) MXPA00007986A (https=)
PL (1) PL194096B1 (https=)
PT (1) PT1064009E (https=)
RU (2) RU2228188C2 (https=)
SE (1) SE1064009T4 (https=)
TR (1) TR200002686T2 (https=)
WO (1) WO1999047149A1 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10123503A1 (de) * 2001-05-15 2002-11-21 Bionorica Ag Verwendung von Extrakten und Zubereitungen aus Irisgewächsen und Tectorigenin als organselektives Arzneimittel zur Behandlung von sexualhormon-abhängigen Erkrankungen des Urogenitaltraktes
DE10127897A1 (de) * 2001-06-08 2002-12-19 Bionorica Ag Manteltablette mit Pflanzentrockenextraktkern
DE10146159A1 (de) * 2001-09-19 2003-04-10 Bionorica Ag Verwendung von Extrakten aus Cimicifuga-Arten als organselektives Arzneimittel zur Behandlung von sexualhormonabhängigen Erkrankungen des Urogenitaltraktes
DE10206390A1 (de) * 2002-02-15 2003-08-28 Bionorica Ag Verwendung von selektiv den Estrogenrezeptor beta modulierenden phytoestrogenhaltigen Extrakten

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Publication number Priority date Publication date Assignee Title
JP2000302667A (ja) * 1999-04-23 2000-10-31 Kobe Tennenbutsu Kagaku Kk 豊胸促進剤
CA2414247C (en) * 2000-06-29 2012-11-27 Quick-Med Technologies, Inc. Cosmetic composition and method comprising a hydroxamate mmpi and a triterpenoid glycoside
TWI303990B (en) 2000-10-17 2008-12-11 Pfizer Prod Inc New use of estrogen agonists/antagonists for improving vascular health
DE10054641A1 (de) 2000-11-03 2002-05-16 Schaper & Bruemmer Gmbh Verwendung einer Zubereitung von Cimicifuga racemosa
EP1325681A1 (en) * 2001-12-11 2003-07-09 Société des Produits Nestlé S.A. Composition for promotion of bone growth and maintenance of bone health
JP4605984B2 (ja) * 2002-12-20 2011-01-05 アサヒビール株式会社 ストレス緩和剤
DE602004020463D1 (de) * 2003-05-15 2009-05-20 Chengdu Dikang Pharmaceutical Isoflavonderivative von tectoridin, deren herstellung und antivirale medikamente, die diese als wirksame bestandteile enthalten
EP1588739A1 (en) * 2004-04-23 2005-10-26 Schaper & Brümmer Gmbh & Co. Kg Composition comprising a combination of calcium, Cimicifugae racemosae rhizoma and vitamin D and its use as a pharmaceutical in conditions or disorders associated with or resulting from calcium deficiency or as a nutritional supplement
EP1591143A1 (en) * 2004-04-26 2005-11-02 Schaper & Brümmer Gmbh & Co. Kg Composition comprising a combination of Calcium, Cimicifugae racemosae rhizoma and vitamin D and its use as a pharmaceutical in conditions or disorders associated with or resulting from calcium deficiency or as a nutritional supplement
US7887851B2 (en) 2004-06-07 2011-02-15 Kao Corporation Aromatase activator
CN100381435C (zh) * 2005-03-24 2008-04-16 深圳海王药业有限公司 射干总黄酮提取物及其制备方法和其在药物制备中的应用
EP1745796A1 (de) 2005-07-19 2007-01-24 Bionorica Research GmbH Kombinationspräparat insbesondere zur Therapie des Prostatakarzinoms
CN101057854B (zh) * 2006-05-31 2010-05-12 南京大学 升麻环菠萝蜜烷型三萜类化合物在抗骨质疏松及更年期综合症的用途
DE102007044916A1 (de) 2007-09-19 2009-04-23 Bionorica Ag Kosmetische oder dermatologische Zusammensetzung zur topischen Verwendung
KR100928013B1 (ko) * 2008-01-25 2009-11-24 이화여자대학교 산학협력단 범부채 추출물을 이용한 돌피의 생장 촉진방법 및 이방법을 적용한 중금속 오염 토양의 정화방법
CN101797265A (zh) * 2010-04-09 2010-08-11 中国人民解放军第二军医大学 射干总异黄酮或异黄酮类化合物在制备防治妇女病的药物或食品中的应用
EP2545932A1 (de) 2011-07-12 2013-01-16 Bionorica Se Ausgewählte Cimicifuga-Fraktionen zur Behandlung von Osteoporose
WO2013007807A1 (de) 2011-07-12 2013-01-17 Bionorica Se Ausgewählte cimicifuga-fraktionen zur behandlung von osteoporose
EP2620155A1 (de) 2012-01-30 2013-07-31 Bionorica SE Arzneimittel enthaltend Cimicifuga zur Anwendung bei der Behandlung von Sarkopenie und Herzmuskelschwäche
CN102525907B (zh) * 2012-02-22 2013-06-05 四川省中医药科学院 鸢尾苷元磺酸钠注射液
CN102631363A (zh) * 2012-04-11 2012-08-15 李超生 鸢尾苷在制备防治骨质疏松症的药物中的应用
KR20150018831A (ko) * 2012-06-22 2015-02-24 골든 바이오테크놀러지 코포레이션 동맥경화성 혈관 질환을 치료하기 위한 방법 및 조성물
AU2013285492B2 (en) 2012-07-03 2015-11-12 Max Zeller Soehne Ag Novel pharmacological use of Cimicifuga extract
JP2014091706A (ja) * 2012-11-02 2014-05-19 Kao Corp Glp−1分泌促進剤
KR101965849B1 (ko) * 2017-03-07 2019-04-04 주식회사 엘지생활건강 텍토리게닌 7-0-자일로실글루코시드를 포함하는 여성 갱년기 증상 완화용 조성물
KR101964841B1 (ko) * 2017-03-07 2019-08-07 주식회사 엘지생활건강 여성 갱년기 증상 개선용 조성물
TWI761372B (zh) * 2017-09-22 2022-04-21 日商東洋新藥股份有限公司 組合物
WO2020141083A1 (en) 2018-12-31 2020-07-09 Max Zeller Soehne Ag Combination of cimicifuga and petasites extracts for anticancer therapy and prophylaxis

Citations (1)

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DE10123503A1 (de) * 2001-05-15 2002-11-21 Bionorica Ag Verwendung von Extrakten und Zubereitungen aus Irisgewächsen und Tectorigenin als organselektives Arzneimittel zur Behandlung von sexualhormon-abhängigen Erkrankungen des Urogenitaltraktes
DE10127897A1 (de) * 2001-06-08 2002-12-19 Bionorica Ag Manteltablette mit Pflanzentrockenextraktkern
DE10127897B4 (de) * 2001-06-08 2006-04-20 Bionorica Ag Manteltablette mit Pflanzentrockenextrakten
US7629005B2 (en) 2001-06-08 2009-12-08 Bionorica Ag Pharmaceutical formulation consisting of a plant dry extract with a calcium coating
DE10146159A1 (de) * 2001-09-19 2003-04-10 Bionorica Ag Verwendung von Extrakten aus Cimicifuga-Arten als organselektives Arzneimittel zur Behandlung von sexualhormonabhängigen Erkrankungen des Urogenitaltraktes
DE10206390A1 (de) * 2002-02-15 2003-08-28 Bionorica Ag Verwendung von selektiv den Estrogenrezeptor beta modulierenden phytoestrogenhaltigen Extrakten

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