DE602004020463D1 - Isoflavonderivative von tectoridin, deren herstellung und antivirale medikamente, die diese als wirksame bestandteile enthalten - Google Patents
Isoflavonderivative von tectoridin, deren herstellung und antivirale medikamente, die diese als wirksame bestandteile enthaltenInfo
- Publication number
- DE602004020463D1 DE602004020463D1 DE602004020463T DE602004020463T DE602004020463D1 DE 602004020463 D1 DE602004020463 D1 DE 602004020463D1 DE 602004020463 T DE602004020463 T DE 602004020463T DE 602004020463 T DE602004020463 T DE 602004020463T DE 602004020463 D1 DE602004020463 D1 DE 602004020463D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- tectoridine
- effective ingredients
- medicaments containing
- isoflavone derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 229930012930 isoflavone derivative Natural products 0.000 title abstract 2
- 150000002515 isoflavone derivatives Chemical class 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000004615 ingredient Substances 0.000 title 1
- XKNZYDKRYPYTHS-UHFFFAOYSA-N irisolidone-7-O-alpha-D-glucoside Natural products COc1ccc(cc1)C2=COc3cc(OC4OC(CO)C(O)C(O)C4O)c(OC)c(O)c3C2=O XKNZYDKRYPYTHS-UHFFFAOYSA-N 0.000 title 1
- FHFSSMDJUNVMNY-UHFFFAOYSA-N tectoridin Natural products COc1c(O)c2C(=O)C(=COc2cc1OC3OC(CO)C(O)C(O)C3O)c4cccc(O)c4 FHFSSMDJUNVMNY-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000470 constituent Substances 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- UYLQOGTYNFVQQX-UHFFFAOYSA-N psi-tectorigenin Natural products COC1=C(O)C=C(O)C(C2=O)=C1OC=C2C1=CC=C(O)C=C1 UYLQOGTYNFVQQX-UHFFFAOYSA-N 0.000 abstract 1
- OYUJPVCKGSEYDD-UHFFFAOYSA-N tectorigenin Natural products COc1c(O)cc2OCC(C(=O)c2c1O)c1ccc(O)cc1 OYUJPVCKGSEYDD-UHFFFAOYSA-N 0.000 abstract 1
- OBBCRPUNCUPUOS-UHFFFAOYSA-N tektorigenin Natural products O=C1C2=C(O)C(OC)=C(O)C=C2OC=C1C1=CC=C(O)C=C1 OBBCRPUNCUPUOS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
- C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN03117865 | 2003-05-15 | ||
| PCT/CN2004/000481 WO2004111027A1 (fr) | 2003-05-15 | 2004-05-14 | Derives isoflavoniques de tectoridine, preparation de ces derives et medicaments antiviraux contenant ces derives comme ingredients efficaces |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602004020463D1 true DE602004020463D1 (de) | 2009-05-20 |
Family
ID=33546175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004020463T Expired - Lifetime DE602004020463D1 (de) | 2003-05-15 | 2004-05-14 | Isoflavonderivative von tectoridin, deren herstellung und antivirale medikamente, die diese als wirksame bestandteile enthalten |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7902253B2 (de) |
| EP (1) | EP1630160B1 (de) |
| JP (1) | JP4654187B2 (de) |
| KR (1) | KR101099967B1 (de) |
| CN (1) | CN1285586C (de) |
| AT (1) | ATE427944T1 (de) |
| DE (1) | DE602004020463D1 (de) |
| RU (1) | RU2332410C2 (de) |
| WO (1) | WO2004111027A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100448450C (zh) * | 2005-04-01 | 2009-01-07 | 四川省中药研究所 | 鸢尾总黄酮提取物的用途 |
| CN100431581C (zh) * | 2006-01-20 | 2008-11-12 | 丽珠医药集团股份有限公司 | 治疗禽流感的中药组合物、制备方法及其用途 |
| CN1907979B (zh) * | 2006-08-18 | 2010-05-12 | 山东省医学科学院药物研究所 | 8-亚甲基-甲胺-尼泊尔鸢尾异黄酮和以该化合物为活性成分的药物组合物 |
| CN101723926B (zh) * | 2008-10-10 | 2012-02-22 | 四川省中医药科学院 | 一种异黄酮衍生物及其制备方法和用途 |
| MX2012007305A (es) * | 2009-12-22 | 2012-07-04 | Procter & Gamble | Composicion liquida de limpieza y/o lavado. |
| EP2560652A4 (de) | 2010-04-23 | 2013-08-14 | Kineta Inc | Antivirale verbindungen |
| CN101863870B (zh) * | 2010-06-03 | 2012-07-25 | 中国药科大学 | 一种鸢尾苷元衍生物、其制法及其治疗前列腺疾病的应用 |
| EP2678019A4 (de) | 2011-02-25 | 2015-05-13 | Kineta Inc | Verfahren und zellen zur identifizierung von rig-i-pfadregulatoren |
| CN102603834B (zh) * | 2012-01-17 | 2014-03-12 | 武汉回盛生物科技有限公司 | 一种从川射干中提取、分离射干苷的方法 |
| CN102525907B (zh) * | 2012-02-22 | 2013-06-05 | 四川省中医药科学院 | 鸢尾苷元磺酸钠注射液 |
| CN103202807B (zh) * | 2013-04-25 | 2014-10-01 | 四川省中医药科学院 | 射干苷元注射液 |
| CN104606148B (zh) * | 2014-12-29 | 2017-10-27 | 重庆药友制药有限责任公司 | 一种注射用炎琥宁制剂及其制备方法 |
| CN106554339B (zh) * | 2016-11-01 | 2019-03-08 | 四川省中医药科学院 | 一种异黄酮衍生物及其制备方法和用途 |
| CN109666015B (zh) * | 2018-12-13 | 2021-04-16 | 四川省中医药科学院 | 一种射干苷元Mannich碱衍生物及其制备方法和应用 |
| WO2020185620A1 (en) * | 2019-03-08 | 2020-09-17 | Microbiotix, Inc. | Inhibition of adenovirus with filociclovir |
| CN110396077B (zh) * | 2019-04-19 | 2021-02-12 | 四川省中医药科学院 | 一种射干苷元磺酸钠的制备方法 |
| CN115819391A (zh) * | 2021-09-17 | 2023-03-21 | 中国科学院上海药物研究所 | 一类黄芩素衍生物、其制备方法和用途 |
| CN115093388B (zh) * | 2022-07-27 | 2023-12-05 | 湖南正清制药集团股份有限公司 | 一种黄酮类化合物及其制备方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ193316A (en) * | 1979-04-10 | 1984-07-31 | Hoffmann La Roche | 3-alkoxyflavone derivatives and pharmaceutical compositions |
| US4352782A (en) * | 1981-02-20 | 1982-10-05 | Rocket Research Company | Catalytic gas generator |
| US4342753A (en) * | 1981-06-15 | 1982-08-03 | American Cyanamid Company | Carboxyalkyl derivatives of rutin poly(H-)sulfate |
| JPS6112A (ja) * | 1984-06-08 | 1986-01-06 | Takeda Chem Ind Ltd | 混合粉砕物 |
| DE3485000D1 (de) * | 1983-06-28 | 1991-10-10 | Takeda Chemical Industries Ltd | Gemahlene mischung. |
| DE19812204A1 (de) * | 1998-03-19 | 1999-11-04 | Plantamed Arzneimittel Gmbh | Verwendung von Extrakten aus Cimicifuga racemosa und Belamcanda sinensis als estrogenartiges organselektives Arzneimittel ohne uterotrope Wirkung |
| US20050037100A1 (en) * | 1998-03-19 | 2005-02-17 | Bionorica Ag | Utilization of extracts from iris plants, cimicifuga racemose and tectorigenin as an estrogen-like organ-selective medicament without uterotropic |
| US6541613B2 (en) * | 2000-12-15 | 2003-04-01 | Uyrex Corporation | Isoflavone derivatives |
| PL205635B1 (pl) * | 2001-04-09 | 2010-05-31 | Inst Farmaceutyczny | Nowe pochodne genisteiny i zawierające je środki farmaceutyczne |
-
2004
- 2004-05-14 EP EP04732921A patent/EP1630160B1/de not_active Expired - Lifetime
- 2004-05-14 RU RU2005138163/04A patent/RU2332410C2/ru not_active IP Right Cessation
- 2004-05-14 JP JP2006529555A patent/JP4654187B2/ja not_active Expired - Fee Related
- 2004-05-14 DE DE602004020463T patent/DE602004020463D1/de not_active Expired - Lifetime
- 2004-05-14 US US10/556,776 patent/US7902253B2/en not_active Expired - Fee Related
- 2004-05-14 AT AT04732921T patent/ATE427944T1/de not_active IP Right Cessation
- 2004-05-14 WO PCT/CN2004/000481 patent/WO2004111027A1/zh active Application Filing
- 2004-05-14 KR KR1020057021814A patent/KR101099967B1/ko not_active IP Right Cessation
- 2004-05-14 CN CNB2004100444846A patent/CN1285586C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20070123566A1 (en) | 2007-05-31 |
| CN1594308A (zh) | 2005-03-16 |
| KR20060034221A (ko) | 2006-04-21 |
| ATE427944T1 (de) | 2009-04-15 |
| EP1630160A4 (de) | 2008-01-16 |
| CN1285586C (zh) | 2006-11-22 |
| JP2007515389A (ja) | 2007-06-14 |
| RU2332410C2 (ru) | 2008-08-27 |
| JP4654187B2 (ja) | 2011-03-16 |
| WO2004111027A1 (fr) | 2004-12-23 |
| EP1630160A1 (de) | 2006-03-01 |
| EP1630160B1 (de) | 2009-04-08 |
| US7902253B2 (en) | 2011-03-08 |
| KR101099967B1 (ko) | 2011-12-28 |
| RU2005138163A (ru) | 2007-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |