BR0208053A - Sìntese de moléculas isoflavonas diméricas, composições contendo as mesmas e seus usos como agentes terapêuticos - Google Patents
Sìntese de moléculas isoflavonas diméricas, composições contendo as mesmas e seus usos como agentes terapêuticosInfo
- Publication number
- BR0208053A BR0208053A BR0208053-2A BR0208053A BR0208053A BR 0208053 A BR0208053 A BR 0208053A BR 0208053 A BR0208053 A BR 0208053A BR 0208053 A BR0208053 A BR 0208053A
- Authority
- BR
- Brazil
- Prior art keywords
- therapeutic agents
- compositions containing
- dimeric
- molecules
- isoflavones
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
- C07D311/38—2,3-Dihydro derivatives, e.g. isoflavanones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Pregnancy & Childbirth (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
Abstract
"SìNTESE DE MOLéCULAS ISOFLAVONAS DIMéRICAS, COMPOSIçõES CONTENDO AS MESMAS E SEUS USOS COMO AGENTES TERAPêUTICOS". Um composto da fórmula geral (I) ou (II) onde X é o, NR~ 4~ ou S e R~ 1~-R~ 8~ são conforme definidos na especificação.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPR3633A AUPR363301A0 (en) | 2001-03-08 | 2001-03-08 | Dimeric isoflavones |
PCT/AU2002/000264 WO2002070502A1 (en) | 2001-03-08 | 2002-03-08 | Dimeric isoflavones |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0208053A true BR0208053A (pt) | 2004-02-25 |
Family
ID=3827642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0208053-2A BR0208053A (pt) | 2001-03-08 | 2002-03-08 | Sìntese de moléculas isoflavonas diméricas, composições contendo as mesmas e seus usos como agentes terapêuticos |
Country Status (15)
Country | Link |
---|---|
US (1) | US7312344B2 (pt) |
EP (1) | EP1373242A4 (pt) |
JP (1) | JP2004529900A (pt) |
CN (1) | CN100436439C (pt) |
AU (1) | AUPR363301A0 (pt) |
BR (1) | BR0208053A (pt) |
CA (1) | CA2440642A1 (pt) |
CZ (1) | CZ20032396A3 (pt) |
HK (1) | HK1066797A1 (pt) |
HU (1) | HUP0303463A3 (pt) |
IL (2) | IL157750A0 (pt) |
MX (1) | MXPA03008076A (pt) |
NO (1) | NO20033898L (pt) |
NZ (1) | NZ528067A (pt) |
WO (1) | WO2002070502A1 (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0656786T3 (da) * | 1992-05-19 | 2004-11-08 | Novogen Res Pty Ltd | Anvendelse af isoflavonphytoöstrogenekstrakter af soja eller klöver |
WO1998050026A1 (en) * | 1997-05-01 | 1998-11-12 | Novogen Inc | Treatment or prevention of menopausal symptoms and osteoporosis |
AUPP112497A0 (en) * | 1997-12-24 | 1998-01-22 | Novogen Research Pty Ltd | Compositions and method for protecting skin from UV induced immunosupression and skin damage |
AUPQ520300A0 (en) * | 2000-01-21 | 2000-02-17 | Novogen Research Pty Ltd | Food product and process |
MXPA05003202A (es) * | 2002-09-23 | 2005-07-05 | Novogen Res Pty Ltd | Fotoenvejecimiento de la piel y tratamiento de dano actinico. |
US7790762B2 (en) | 2002-10-31 | 2010-09-07 | National Jewish Health | Compounds and methods for thiol-containing compound efflux and cancer treatment |
US20040087527A1 (en) * | 2002-10-31 | 2004-05-06 | Day Brian J. | Methods for treatment of thiol-containing compound deficient conditions |
JP5143993B2 (ja) * | 2003-03-26 | 2013-02-13 | 株式会社産学連携機構九州 | エストロゲン様活性剤 |
JP4668553B2 (ja) * | 2004-05-27 | 2011-04-13 | サントリーホールディングス株式会社 | リパーゼ阻害活性および/または抗酸化活性を有するエピガロカテキン二量体および三量体 |
EP2526941A1 (en) | 2005-03-24 | 2012-11-28 | Marshall Edwards, Inc. | Anti-inflammatory Modalities |
MY169554A (en) | 2005-12-06 | 2019-04-22 | Otsuka Pharma Co Ltd | Equal-containing fermentation product of soybean embryonic axis, and method for production thereof |
US8242100B2 (en) * | 2006-02-28 | 2012-08-14 | Nestec Sa | Compositions and methods for inducing bone growth and inhibiting bone loss |
JP5172913B2 (ja) * | 2010-09-03 | 2013-03-27 | サントリーホールディングス株式会社 | リパーゼ阻害活性および/または抗酸化活性を有するエピガロカテキン二量体および三量体 |
EP3439642A4 (en) * | 2016-04-06 | 2019-11-13 | Noxopharm Limited | IMPROVEMENTS IN RADIATION THERAPY |
JP2019513828A (ja) | 2016-04-06 | 2019-05-30 | ノクソファーム リミティド | 改善された薬物動態を有するイソフラボノイド組成物 |
WO2019051562A1 (en) * | 2017-09-15 | 2019-03-21 | Norbio No. 1 Pty Ltd | TREATMENT OF EXCITOTOXICITY |
CN109985055B (zh) * | 2019-04-03 | 2021-07-09 | 广州中医药大学(广州中医药研究院) | 一种抗脑缺血再灌注损伤的药物组合物及其应用 |
AU2021247415A1 (en) | 2020-03-30 | 2022-09-29 | Noxopharm Limited | Methods for the treatment of inflammation associated with infection |
WO2023107507A1 (en) * | 2021-12-06 | 2023-06-15 | University Of Kentucky Research Foundation | Diaminobutoxy-substituted isoflavonoids as mitochondrial complex i inhibitors for cancer treatment |
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DE1543749A1 (de) * | 1966-02-16 | 1969-12-11 | Merck Ag E | Verfahren zur Herstellung von 3,4-cis-4-Aryl-isoflavanen |
JPS54734B2 (pt) | 1973-05-14 | 1979-01-16 | ||
US3973608A (en) * | 1973-08-01 | 1976-08-10 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Microbial production of certain isoflavones |
JPS576427B2 (pt) | 1974-01-25 | 1982-02-04 | ||
HU168753B (pt) | 1974-05-03 | 1976-07-28 | ||
JPS50160483A (pt) | 1974-06-19 | 1975-12-25 | ||
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-
2001
- 2001-03-08 AU AUPR3633A patent/AUPR363301A0/en not_active Abandoned
-
2002
- 2002-03-08 CN CNB028090195A patent/CN100436439C/zh not_active Expired - Fee Related
- 2002-03-08 CA CA002440642A patent/CA2440642A1/en not_active Abandoned
- 2002-03-08 IL IL15775002A patent/IL157750A0/xx unknown
- 2002-03-08 EP EP02704471A patent/EP1373242A4/en not_active Withdrawn
- 2002-03-08 CZ CZ20032396A patent/CZ20032396A3/cs unknown
- 2002-03-08 MX MXPA03008076A patent/MXPA03008076A/es active IP Right Grant
- 2002-03-08 BR BR0208053-2A patent/BR0208053A/pt not_active IP Right Cessation
- 2002-03-08 US US10/469,957 patent/US7312344B2/en not_active Expired - Fee Related
- 2002-03-08 HU HU0303463A patent/HUP0303463A3/hu unknown
- 2002-03-08 WO PCT/AU2002/000264 patent/WO2002070502A1/en active IP Right Grant
- 2002-03-08 JP JP2002569822A patent/JP2004529900A/ja active Pending
- 2002-03-08 NZ NZ528067A patent/NZ528067A/en unknown
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2003
- 2003-09-03 NO NO20033898A patent/NO20033898L/no not_active Application Discontinuation
- 2003-09-04 IL IL157750A patent/IL157750A/en not_active IP Right Cessation
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2004
- 2004-12-07 HK HK04109694.6A patent/HK1066797A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL157750A (en) | 2009-08-03 |
NO20033898L (no) | 2003-10-30 |
HK1066797A1 (en) | 2005-04-01 |
US7312344B2 (en) | 2007-12-25 |
IL157750A0 (en) | 2004-03-28 |
CZ20032396A3 (cs) | 2004-02-18 |
EP1373242A1 (en) | 2004-01-02 |
AUPR363301A0 (en) | 2001-04-05 |
CN100436439C (zh) | 2008-11-26 |
JP2004529900A (ja) | 2004-09-30 |
EP1373242A4 (en) | 2005-08-24 |
WO2002070502A1 (en) | 2002-09-12 |
NZ528067A (en) | 2005-09-30 |
NO20033898D0 (no) | 2003-09-03 |
CN1505618A (zh) | 2004-06-16 |
HUP0303463A3 (en) | 2005-02-28 |
HUP0303463A1 (hu) | 2004-01-28 |
US20040152761A1 (en) | 2004-08-05 |
CA2440642A1 (en) | 2002-09-12 |
MXPA03008076A (es) | 2004-03-16 |
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